Articles tagged with Osteoporosis
The new guidelines update Osteoporosis Canada's recommendations on vitamin D intake for Canadians, citing the need for more research into optimal doses and safe upper limits. The recommended daily supplements range from 400-1000 IU for adults under 50, with higher doses required for those over 50.
Researchers at Loyola University Health System found long-lasting disruptions in hundreds of genes involved in bone formation in rats exposed to binge drinking. The study suggests that lifestyle-related damage done during young adulthood may have repercussions lasting decades.
The new guidelines recommend daily supplements of 400 to 1000 IU for adults under 50 without osteoporosis, increasing to 800-2000 IU for those over 50. Canadians can safely take daily vitamin D supplements up to 2000 IU without medical supervision.
A study of 825 postmenopausal women found that those with low calcium intake were more likely to develop both osteoporosis and hypertension. Researchers suggest that a low calcium diet may be a risk factor for these conditions.
A study found that patients taking bisphosphonates are often uninformed about the drug's possible side effects on oral health, including bisphosphonate-associated osteonecrosis of the jaw (BON). The researchers interviewed 73 participants and discovered that 82% were unsure if their physicians had informed them about potential adverse ...
The International Osteoporosis Foundation recommends optimal vitamin D status through serum 25OHD levels and effective sun exposure. Vitamin D deficiency is associated with decreased muscle strength, increased risk of falls and osteoporotic fractures.
The IOF-Servier Young Investigator Research Grant was awarded to two young researchers, Dr. Frank DeVries and Dr. Davide Ruffoni, for their innovative projects on osteoporosis. The grant aims to estimate the risk of fracture in patients with bariatric surgery and understand the mechanisms of implant integration in osteoporotic bone.
Researchers found a relationship between time spent in vigorous physical activity and strength of the femoral neck, independent of diet and lifestyle. The study suggests increasing physical activity in childhood can improve skeletal bone development and reduce the risk of osteoporosis later in life.
The ESCEO-IOF-ABBH Young Investigator Award recognizes the work of young researchers who have made significant contributions to osteoporosis research. The award is presented to researchers under the age of 40 who have submitted high-quality abstracts to the IOF WCO-ECCEO10 congress.
The International Osteoporosis Foundation (IOF) has honored long-time associate Professor José Zanchetta with the prestigious Pierre Delmas Award. The award recognizes Dr. Zanchetta's commitment to advancing osteoporosis awareness and treatment in the Latin American region.
Research from the ICUROS study reveals that hospitalized vertebral fracture patients have a more substantial decrease in quality of life. This is attributed to co-morbidities and higher severity of fractures among hospitalized individuals.
The International Osteoporosis Foundation has announced the launch of new FRAX tools at the World Congress on Osteoporosis. The updated tools include a convenient iPhone application that allows for easy access to the fracture-risk calculator, and multilanguage tear sheets that can be completed in various languages.
John A. Kanis receives IOF Medal of Achievement for his long-standing and distinguished career advancing the field of osteoporosis research. He has published widely on disorders of skeletal metabolism, including osteoporosis, Paget's disease of bone, hyperparathyroidism, renal osteodystrophy and neoplasia.
Four ESCEO-AMGEN Osteoporosis Fellowships valued at $50,000 each were awarded to outstanding researchers in osteoporosis, with projects focusing on vitamin D status, osteoporosis treatment preferences, and ephrin B2 system. The Fellowship Programme aims to advance clinical care and prevention through training physicians and PhDs.
The study analyzed over 11,000 elderly men in Sweden, US, and Hong Kong, finding that age significantly impacts the risk of falling, while ethnicity and environment play a role. The proportion of frequent fallers varied across countries, with highest rates in the US, followed by Sweden, and lowest in Hong Kong.
A new study found that long-term use of DMPA injections increases the risk of bone fractures in women under 50, with a 50% higher risk for users of progestin-only contraceptives. The results suggest that combined estrogen-containing oral contraceptives do not increase fracture risk
Young people with inflammatory bowel diseases are at increased risk of fracture due to low bone mass and poor bone architecture. This is attributed to factors such as poor nutrient absorption, glucocorticoid medication use, and altered trabecular bone tissue microarchitecture.
A new study suggests that higher dietary protein intake can lower the risk of hip fractures in elderly individuals. The research, conducted on 946 seniors from the Framingham Osteoporosis Study, found that those consuming more protein had a significantly lower incidence of hip fractures compared to those with lower protein intake.
Professor Pierre Jean Meunier received the prestigious Pierre Delmas Prize at the World Congress on Osteoporosis 2010 for his major scientific contributions to the study of bone and mineral diseases. The award honors his influential work in osteoporosis research, mentorship, and education.
A team of international researchers has identified 20 genes associated with osteoporosis and bone weakness, including 13 genes never previously associated with the disease. The study, published in Nature Genetics, provides new insights into the genetic mechanisms that control bone strength.
A new study highlights the importance of osteoporosis screenings for fracture patients, who are at a high risk of future fractures. Women should ask their physicians questions about their bone health to educate themselves and receive timely treatment.
Researchers found that martial arts fall exercises can reduce hip impact forces, making them safe for older adults with osteoporosis if precautions are taken. The study suggests that martial arts training could be a viable option for preventing hip fractures in this population.
A recent international study on osteoporosis in women has found that most postmenopausal women are not aware of their actual risk of debilitating bone breaks. The study, which involved over 60,000 women aged 55 and older in 10 countries, highlights the need for public education about osteoporosis risk factors and treatment.
A landmark international study found that many postmenopausal women at high risk of fractures fail to recognize their risk factors. The study highlights the need for improved education about osteoporosis risk factors and treatment to prevent debilitating fractures.
A landmark international study of over 60,000 women found that many are unaware of their risk factors for debilitating fractures, which can lead to chronic pain, reduced mobility, and increased mortality. The study emphasizes the need for improved education on osteoporosis risk factors and treatment options.
A new study has discovered that the 'vegetable lamb' plant contains substances with promise as treatments for osteoporosis. The plant's compounds blocked the formation of bone-destroying osteoclasts in up to 97% of laboratory cultures without harming other cells.
A new study led by UCSF researchers found that unusual femur fractures are extremely rare in patients with osteoporosis, even those taking bisphosphonates for extended periods. The study's findings provide context to reports of these fractures and highlight the importance of weighing treatment benefits against potential risks.
A study of nearly 1,500 patients over seven years found that vertebroplasty significantly improves back pain within hours and provides long-term pain relief. Collaboration between interventional radiologists and medical experts is crucial for the best results.
Researchers found that bisphosphonate treatments can alter the material properties of bone, potentially affecting its mechanical integrity and contributing to atypical fractures. Long-term suppression of bone remodeling may lead to brittle bone prone to fractures.
A University of Alberta study found that pharmacist interventions led to a 200% increase in patients getting further assessment and diagnosis for osteoporosis. Pharmacists can help with education and screening, addressing the silent disease that often goes undiagnosed after age 50.
Researchers at Columbia University Irving Medical Center found that inhibiting serotonin synthesis in the gut effectively cured osteoporosis in mice and rats. The compound, LP533401, prevents bone breakdown while building new bone, offering a potential treatment for millions of osteoporosis sufferers.
A Swedish study of over 3,700 grandparents and their grandsons found that men with a male relative who suffered a hip fracture had up to 5% less bone density and 4% smaller bones than those without. This reduction in bone size increases the risk of fractures threefold.
Researchers are launching a human trial of a new osteoporosis drug, PTHrP, which may increase bone density more dramatically with fewer side effects than current treatments. The study aims to compare the efficacy of PTHrP with existing FDA-approved drugs for osteoporosis treatment.
In a study, oncostatin M was found to promote bone formation by blocking the production of a protein that inhibits bone growth when signaling through leukemia inhibitory factor receptor. This indicates the existence of a pathway for stimulating bone formation independently of bone destruction.
Researchers at Queen Mary University of London have discovered fundamental differences between skull and limb bones that could lead to new osteoporosis treatments. The study found significant variations in gene activity and behavior between the two types of bone cells.
Current UK guidelines limit postmenopausal women's treatment options due to bone mass T-score criteria. Alternative therapies are available but often require stricter conditions.
A new cause of osteoporosis has been identified: a mutation in the miR-2861 precursor that blocks expression of this crucial microRNA. This microRNA promotes bone formation and its absence is linked to primary osteoporosis in humans.
Researchers have identified a microRNA (miR-2861) that regulates bone formation, and its mutation is linked to primary osteoporosis. In addition, studies on Lyme disease transmission revealed a biphasic mode of dissemination by Borrelia burgdorferi microbes within ticks.
A large-scale meta-analysis has found a clear connection between depression and reduced bone density, increasing the risk of osteoporosis. The study, conducted by Hebrew University researchers, reveals that young women are particularly at risk, especially those with clinical depression.
A Kaiser Permanente study found that aggressively managing patients at risk for osteoporosis can reduce the hip fracture rate by 25%. The study, which followed 650,000 men and women over 50 years old, found a 38% drop in hip fractures and prevented 970 hip fractures in 2007.
A recent study found that patients treated with teriparatide for 36 months had a greater increase in bone mineral density (BMD) and fewer new vertebral fractures than those treated with alendronate. The study also observed higher levels of calcium concentrations in the teriparatide group.
A new study reveals that people with coeliac disease are at risk of developing osteoporosis due to an immune system attack on their bone tissue. Researchers have identified a protein called osteoprotegerin as the target of this attack, leading to rapid bone destruction and severe osteoporosis.
A study published in the Journal of Bone and Joint Surgery suggests that women over 50 with a wrist fracture are less likely to be evaluated and treated for osteoporosis compared to those with hip or spine fractures. The study highlights barriers to evaluation, including clinical inertia, cost concerns, and lack of clarity on responsib...
The International Osteoporosis Foundation's Health Professional Awareness Grants support innovative projects promoting osteoporosis knowledge among clinicians and allied health professionals. Five grants were awarded to patient societies in Armenia, Austria, Bulgaria, Hungary, and Singapore for their awareness programs targeting health...
The Arthritis Foundation of India Trust has won the prestigious IOF Linda Edwards Memorial Award for its innovative campaigns to raise awareness about osteoporosis. The organization, established in 2002, has been recognized for its efforts to improve bone health and patient care across India.
The International Osteoporosis Foundation reports a growing problem of osteoporosis in Asia, with hip fracture incidence increasing 2-to 3-fold over the past 30 years. Vitamin D deficiency and low calcium intake are widespread, resulting in significant personal suffering, lost productivity, and long-term dependence.
A Loyola University Health System study found that breast cancer patients can prevent bone loss by correcting secondary causes, such as vitamin D deficiency, and using bisphosphonate osteoporosis drugs. After one year, patients with secondary causes showed stable bone mineral density.
Researchers identify a link between high cholesterol and osteoporosis, with the immune system playing a key role in bone loss. The study found that oxidized LDL triggers an immune response, leading to excessive bone damage.
Hip fracture rates declined by 31.8% in females and 25% in males between 1985 and 2005, with the largest decrease among individuals aged 55-64 years. The reasons for this decline are unclear, but factors such as overweight and obesity may contribute.
A new UCLA study reveals the immune system plays a crucial role in bone loss, with high cholesterol levels contributing to the disease. The research identifies a new approach for treating osteoporosis using immune-based therapies.
A recent study found that the type 1 cannabinoid receptor is key to bone development and osteoporosis. Cannabis may reduce bone strength in young people but protect against osteoporosis in older age.
A new study published in CMAJ found that hip and back fractures in people aged 50 and older significantly increase mortality rates. Approximately 25% of individuals who develop a hip fracture and 16% who develop a spine fracture will die within 5 years.
A recent study published in the Canadian Medical Association Journal found that approximately 25% of men and women who develop hip fractures will die within five years, as well as 16% of those with spine fractures. The study also highlights the importance of fall prevention strategies, osteoporosis medications, and rehabilitation to re...
A new study suggests that an osteoporosis medication may be saving lives by strengthening the immune system. Researchers found that while the reduction in secondary fractures accounted for only 8% of the mortality benefit, the risk of mortality was still 23% lower in patients who received the drug.
The report reveals widespread vitamin D deficiency across six regions, with severe consequences for health and fracture rates. Prevention strategies must be initiated at a national level to address the issue.
Researchers studied postmenopausal women with RA, finding that hip bone mineral density correlated with bone erosion but not spine BMD. The study suggests that inflammation may play a role in both focal erosions and osteoporosis.
A recent study published in Annals of Internal Medicine found that elderly women with hyperkyphosis, or 'dowager's hump,' are at a higher risk for premature death. The study, which analyzed data from over 610 women, suggests that the increased spinal curvature itself may be predictive of adverse health outcomes.
Researchers have identified a potential new focus for treating osteoporosis and periodontitis by inhibiting nuclear factor-kB, a master protein controlling inflammation and immunity. This balance is crucial in bone formation and resorption.
A new study provides clear protocols for clinicians to follow, updating fracture risk algorithms and creating simple tables to guide doctors. The findings suggest that repeat bone density measurements can help prognosis of fracture in patients at risk due to age and other factors.
Patients with vertebral compression fractures experience prolonged intense pain, with over two-thirds reporting severe pain one year after injury. Current treatment and advice are deemed insufficient, requiring revised approaches to improve patient outcomes.