Articles tagged with Osteoporosis
Researchers found that women with low bone density are seven times more likely to benefit from bisphosphonate drugs when their vitamin D levels are above the recommended threshold. Maintaining adequate vitamin D levels is crucial for optimizing osteoporosis treatment, particularly in postmenopausal women.
A lower dose of zoledronic acid has been found to increase bone density and decrease bone resorption, potentially reducing the risk of osteoporotic fractures. The study suggests that a one-fifth or one-half of the recommended dose may be sufficient for this effect.
Research shows bariatric surgery significantly increases fracture risk, with patients experiencing a 2.3-fold higher chance of bone fractures compared to the general population. Patients who underwent gastric bypass surgery had an increased risk of fractures at nearly all skeletal sites, including feet and hands.
A new IOF position paper advocates for coordinator-based systems to optimize outcome in fragility fracture patients, improving diagnosis and treatment of osteoporosis. This approach has been shown to reduce the risk of fractures and save money in healthcare systems.
A study of 1,030 patients with celiac disease found they were 4.5 times more likely to develop osteoporosis compared to healthy individuals. The bone mineral density loss was significantly pronounced in the lumbar spine but not the femoral neck.
Balicatib, a new osteoporosis treatment, causes skin hardening syndromes in patients. Researchers at Boston University School of Medicine found that the drug inhibits CathepsinK, leading to collagen and elastin degradation.
A Canadian study found that 12% of heart failure patients had moderate to severe vertebral compression fractures, a sign of osteoporosis. Only 15% of these patients were being treated for osteoporosis, despite having a higher risk for fractures.
A University of Illinois study suggests that increasing dietary calcium and vitamin D or taking supplements can significantly increase bone mineral density and reduce hip fracture risk. The researchers recommend a 'portfolio diet' with adequate protein, less sodium, and more magnesium and potassium for optimal bone health.
A recent study by American Academy of Orthopaedic Surgeons highlights the lack of knowledge about osteoporosis among certain patient groups, increasing their risk of fractures. Patients with fragility fractures, male individuals, and those who are unemployed or have limited English proficiency tend to know less about osteoporosis.
A review paper by IOF examines global hip fracture incidence trends, finding changes in age-specific rates in different regions. The study highlights the need for further research to understand the socio-economic burden of fragility fractures worldwide.
A study found that green tea and tai chi can enhance bone strength and reduce inflammation in postmenopausal women. The combination of moderate green tea consumption and tai chi practice showed significant benefits in bone markers, muscle strength, and quality of life.
Obese postmenopausal women are almost as likely to fracture as non-obese women, with specific sites like the upper arm, ankle, and lower leg being more prone to fractures in obese individuals. Poor mobility and a history of early menopause also play significant roles.
The ESCEO Young Investigators Awards were presented to Dr. Nick Harvey and Dr. Michaël Hiligsmann for their outstanding contributions to bone and mineral research. Their awards, valued at €2,500, recognize excellence in bone mineral research and are supported by a grant from MSD.
A new study reveals that hip fractures and vertebral fractures are major contributors to the economic cost, with Germany bearing the highest costs. The study estimates that prevention through early risk assessment is key to reducing these costs.
Researchers found that including falls history with clinical risk factors and bone mineral density values significantly enhances the accuracy of fracture prediction models. The study showed a 6% improvement in accuracy for men, with positive predictive values of 21.5% and 29.8% for women.
A recent study published in Osteoporosis International found substantial initial quality of life loss following osteoporotic fractures, particularly for hip and vertebral fractures. The study, part of the ICUROS international patient-based study, identified significant variations in quality of life loss between countries.
Dr. Helena Johansson and Dr. Maria-Belen Zanchetta receive $50,000 USD Fellowship to support their osteoporosis research at Sahlgrenska Academy and Instituto de Investigaciones Metabólicas, respectively. The award aims to promote research excellence in the bone field.
John A. Kanis, a leading expert in bone and mineral diseases, has made significant scientific contributions to the study of osteoporosis. He is currently President of the International Osteoporosis Foundation and WHO Advisor on Osteoporosis.
The Philippine Foundation was awarded a grant to establish an innovative bone health awareness program, promoting healthy nutrition and lifestyle habits to prevent osteoporosis. The program aims to raise awareness and make a real difference in communities, with a focus on education and community engagement.
The IOF-AMGEN/GSK Health Professionals Awareness Grants aim to improve knowledge of osteoporosis among clinicians and allied health professionals. The three grants support innovative projects by IOF member societies that focus on improving knowledge and diagnosis of osteoporosis.
The Association 'Women without Osteoporosis' of Bulgaria has received the 2011 IOF Linda Edwards Memorial Award for its outstanding campaigns to increase awareness, prevention, and treatment of osteoporosis. The award recognizes the organization's efforts to improve care for patients and its dedication to raising osteoporosis awareness.
Professor Gerard Karsenty is awarded the first Herbert A. Fleisch ESCEO-IOF Medal for his pioneering work in understanding skeletal development and physiology. The medal recognizes his outstanding achievements in basic bone science, including identifying Runx2 as a master gene of osteoblast differentiation.
Scientists have identified NOTCH2 as the causative gene for Hajdu-Cheney syndrome, a rare disorder characterized by progressive bone loss and osteoporosis. The study provides vital insight into possible causes of osteoporosis and highlights the gene as a potential target for treating the condition.
Researchers found that tomatoes contain powerful antioxidants like lycopene, which has greater bioavailability after cooking and processing. Tomatoes also have anti-inflammatory functions and a lower risk of certain cancers, cardiovascular disease, osteoporosis and cognitive dysfunction.
A new study found that women taking bisphosphonates for five years or more may be at higher risk of certain kinds of fractures of their thigh bone, but the drugs still prevent hip fractures. The overall risk is low, and researchers recommend continuing use for high-risk patients
Recent studies on PCSK enzymes have shed light on novel functions in diseases such as cardiovascular disorders, osteoporosis, and cancer. The research has revealed that these enzymes may play a crucial role in regulating cholesterol levels and bone formation, offering potential new treatments for dyslipidemia and osteoporosis.
A commonly prescribed osteoporosis drug is associated with a slightly elevated risk of developing osteonecrosis of the jaw, but the risk remains extremely low. Patients taking oral bisphosphonates were nine times more likely to develop the condition than those who didn't.
A recent study found that people taking bisphosphonates for osteoporosis treatment live an extra five years compared to those not receiving the medication. This significant benefit is attributed to bisphosphonates' ability to reduce toxic metal release, which may contribute to improved health outcomes.
Researchers found that people taking bisphosphonates lived longer than those without osteoporosis and even gained an extra five years of life. The study, published in the Journal of Clinical Endocrinology and Metabolism, suggests a possible link between bone health and toxic metal release.
African American patients with hypertension who viewed stories about real patients experienced better blood pressure control compared to usual care. High-volume hospitals for congestive heart failure showed improved patient outcomes but higher costs, contradicting previous studies that only focused on cost-effectiveness.
Key findings show that patients fear fractures but do not always adhere to treatment, while doctors underestimate their patients' adherence and concerns. Community-based online support programs have a great potential to fill information gaps and improve patient-doctor dialogue.
The IOF and IFCC have identified research priorities and recommended specific bone turnover markers (s-PINP and s-CTX) as reference analytes for clinical and observational studies. Standardized protocols would greatly increase the clinical and research potential of BTMs, improving patient management and treatment adherence.
A New Delhi study found that 76.7% of hip fracture patients were vitamin D deficient, with elevated PTH levels also common. The research suggests vitamin D levels may be a useful index for assessing hip fracture risk in elderly people.
The International Osteoporosis Foundation has presented its Young Investigators Awards to researchers from China, India, Japan, Sri Lanka, and Taiwan, highlighting the need for osteoporosis awareness in the region. The awards recognize outstanding research on hip fractures, falls, and vitamin D deficiency, promoting education, innovati...
Experts flag vitamin D deficiency as a major concern in the region, with severe deficiency across India and Pakistan. Interactive maps tracking vitamin D levels by region are being developed to identify problem areas and stimulate research studies.
A new study confirms a rapid rise in hip fractures in Beijing, with significant increases in rates for older adults. The research reveals that the growing elderly population and increasing sedentary lifestyles are major contributors to this trend, posing a serious socio-economic challenge for healthcare systems.
The WHO Fracture Risk Assessment Tool (FRAX) has been released for Singapore, enabling health professionals to accurately assess the absolute risk of osteoporotic fractures. The online calculator, available in 27 country models, provides a 10-year probability of hip fracture and major osteoporotic fractures based on clinical risk factors.
A study presented at the Radiological Society of North America found that excessive internal abdominal fat may harm bone health in women. Research revealed that women with more visceral fat had increased bone marrow fat and decreased bone mineral density.
The Position Paper examines the evidence and concludes that atypical fractures in association with bisphosphonate use are rare. Available evidence shows that the well-known benefits of bisphosphonate treatment outweigh the relatively low risk of these rare, atypical fractures.
A recent study found that bone density remained stable for three years in patients who took a drug holiday from bisphosphonates, a popular class of osteoporosis drugs. The researchers recommend taking drug holidays after four to five years, but the study suggests that this duration may be longer, potentially up to three years.
The FRAX tool was clarified for its use in clinical practice through international discussions, enabling its wider implementation. The tool predicts a patient's 10-year fracture risk based on scientifically validated risk factors.
A team of researchers aims to develop a biological treatment for compression fractures, the most common type of bone fracture in osteoporosis patients. The goal is to promote healing and stimulate normal bone production.
A new report highlights the severe impact of spinal fractures, which can lead to stooped back, acute and chronic back pain, loss of height, and premature death. The IOF calls on health professionals to recognize signs of these fractures in their patients.
A study by the University of Michigan found that teriparatide, a drug marketed for osteoporosis, can also heal bone wounds in gum disease patients. The treatment showed a 29% improvement in bone-level measurements on x-rays, compared to a 3% improvement in the placebo group.
A new study found that Vitamin D deficiency is associated with a higher rate of abnormal bone density and osteoporosis in IBD patients. The study, which included 161 patients, revealed that nearly half of those with IBD under age 50 had reduced bone density.
A new study found that women aged 67 and older with normal bone mineral density scores may not need re-screening in 10 years. The researchers calculated estimated times for 10 percent of the women to transition to osteoporosis, finding that it would take about 16 years for this group to develop osteoporosis.
A new report highlights the severe impact of spinal fractures caused by osteoporosis, with millions at risk of further fractures and long-term disability. Experts call for early diagnosis and treatment to prevent devastating consequences.
Spinal osteoporotic fractures often go undiagnosed and untreated, leading to severe repercussions such as stooped back, acute pain, loss of height, and premature death. The IOF campaign aims to raise awareness and promote prevention, diagnosis, and early treatment.
The new guidelines, published in CMAJ, focus on identifying and managing fractures and assessing risk. Current data indicate that many fracture patients are not appropriately assessed or treated, highlighting the need for improved management of osteoporosis and fragility fractures.
A new Cochrane Systematic Review found that vitamin D supplements have no effect on bone density in healthy children. However, children with low levels of vitamin D may benefit from supplementation.
Researchers at Hebrew University discover a group of substances in the body controlling bone density, leading to development of a new osteoporosis drug. Oleoyl serine increases bone density in both healthy and osteoporotic mice, offering a promising approach to reversing bone loss.
A team of researchers has identified a key player in maintaining bone balance, finding that the protein Maf promotes bone formation and prevents osteoporosis. By understanding this age-related switch in cell type generation, new approaches to treat age-related osteoporosis may be developed.
A new report by the International Osteoporosis Foundation reveals poor post-fracture care in the region, with high mortality rates after hip fractures. The report predicts a significant increase in osteoporotic fractures due to aging populations and limited access to diagnostic tests and medication.
Spanish researchers have discovered a genetic link between the 677C>T variant and osteoporotic vertebral fractures in post-menopausal women. This finding highlights the importance of genetic analysis in identifying individuals at high risk for bone-related illnesses.
A novel nano-CT imaging technique enables researchers to visualize the nano-structure of bone samples with high precision. This allows for better understanding of structural changes related to osteoporosis and development of new therapeutic approaches.
A validated new model can predict postmenopausal osteoporosis incidence and prevalence in different national settings, providing a powerful tool for health policy decision making. The model was developed using Swedish data and showed a 5% margin of error compared to published data.
The study found that spine, hip, and upper leg fractures resulted in the greatest decrease in quality of life. Nearly 40% of women over 50 will experience a fracture, with chronic pain and reduced mobility being common consequences.
Children with celiac disease are at risk for poor bone health, but adding vitamins K and D to their diets can reduce this risk. Incorporating physical activity into daily routines also boosts bone strength and Vitamin D intake through outdoor exercise.
Researchers have discovered that bone cells' spindly extensions can sense mechanical stimulation, signaling the release of bone-growth factors. This breakthrough could lead to therapies for osteoporosis and bone loss associated with aging.
A comprehensive Argentinean epidemiological study found that one out of three women aged 50 or over suffers from osteoporosis, with a prevalence of vertebral fractures in 16% of women aged 50 or older. The study estimated annual costs of hip fractures and vertebral fractures to exceed $250 million USD per year.