Articles tagged with Osteoporosis
A study at the University of Eastern Finland found that abnormal bone properties in children with vertebral fractures and after solid organ transplantation can predict fracture risk. Bone histomorphometry revealed changes in bone composition that could explain increased fracture risk.
A new study found that patients who understand their potential risk for another fracture are more likely to take action. Knowing bone health and osteoporosis is pivotal in preventing future fractures.
Distal radius fractures, a common elderly fracture, require standardized measurement of clinical outcomes to inform evidence-based practice and research. ISFR-ISOF recommendations promote international consensus on core domains for assessment, including pain, function, and participation.
The National Osteoporosis Guideline Group (NOGG) Update 2013 provides updated guidance on the diagnosis and management of osteoporosis. The new recommendations cover glucocorticoid-induced osteoporosis, calcium and vitamin D therapy, and long-term bisphosphonate therapy.
A study published in the Journal of Clinical Endocrinology & Metabolism found that probiotic Lactobacillus reuteri NCIMB 30242 increased circulating vitamin D levels by 25.5 percent in hypercholesterolemic adults over a nine-week intervention.
Researchers found reversal cells covering 80% of resorbed bone surfaces that gradually mature into osteoblasts during the reversal phase. Biopsies from postmenopausal patients with osteoporosis showed a high proportion of arrested cells, associated with bone loss.
A combination of two FDA-approved osteoporosis drugs, denosumab and teriparatide, was found to increase bone density more effectively than single-drug therapy in a small clinical trial. The treatment produced significant improvements in bone mineral density at multiple measured sites, including the lumbar spine and hip.
A new osteoporosis treatment combination of denosumab and teriparatide was found to be more effective than individual therapies, increasing bone density in women with osteoporosis. The study showed significant improvements in BMD at the spine, hip, and femoral neck in women treated with the combination therapy.
A study of 32,383 participants found that prolonged surgical delay after hip fracture significantly increases long-term mortality risk in older adults. The researchers suggested that early surgery may help mitigate this risk and improve patient outcomes.
A new report sets 13 achievable standards for best practice in implementing fracture liaison services worldwide to identify and treat patients at high risk of secondary fractures. The initiative aims to provide essential resources, establish mentoring programs, and promote global recognition for fracture liaison services.
A recent study from India reveals that patients with hip fractures experience high mortality and functional impairment rates, with 30.4% of patients passing away within a year of the fracture, and only 21.9% regaining normal motor function.
A Kaiser Permanente study found that nearly 30% of women with osteoporosis fail to pick up their bisphosphonate prescriptions within 60 days. The study identified patient and physician characteristics, such as age, emergency department utilization, and prescription medication use, that contribute to nonadherence.
Professor Diez-Perez has advanced understanding of osteoporosis through original scientific contributions, including epidemiology and clinical care. He is recognized for promoting medical innovation and improving patient outcomes.
Professor Socrates Papapoulos has made significant contributions to advancing osteoporosis research and advocacy worldwide. He is a renowned researcher at the Leiden University Medical Center and IOF Board member, with over 300 publications and several awards.
Professor Harry Genant has been recognized with the first IOF Olof Johnell Science Award for his influential work in noninvasive imaging methods, clinical advances, and best practice guidelines. He is a distinguished researcher, author, and educator, with extensive contributions to bone science and policy implementation.
A recent study found that simple educational strategies targeting doctors and patients after a fracture significantly improved osteoporosis testing rates, reducing fractures by two fewer per 1,000 patients. Mail-based notice interventions were effective and cost-efficient, with projected savings of $18,000 for every 1,000 patients.
A new EU scorecard highlights significant inequalities in osteoporosis care across European countries. Despite marked differences in fracture risk and services, approximately 57% of high-risk individuals remain untreated, with inadequate access to testing, treatment, and effective medications.
A recent study found that zoledronic acid, a common osteoporosis drug, not only slows bone loss but also increases levels of sclerostin, a biomarker that inhibits bone formation. This suggests that combination treatments may be needed to effectively treat osteoporosis and increase bone mass.
Professor Maria Luisa Brandi was awarded the prestigious ESCEO-IOF Servier Pierre D. Delmas Prize for her major scientific contributions to bone and mineral diseases. She is a renowned researcher with numerous patents and publications, recognized nationally and internationally.
The European Union faces a significant burden of osteoporosis, with 22 million women and 5.5 million men affected. The annual economic cost of new and prior fragility fractures is €37 billion, with costs expected to increase by 25% by 2025.
Dr. Mary Bouxsein has been recognized with the ESCEO-IOF Herbert Fleisch Medal for her outstanding contributions to understanding skeletal fragility through biomechanics. Her work focuses on predicting fracture risk using novel non-invasive imaging techniques.
Researchers found that smoking and depressive symptoms in adolescent girls negatively impact bone accrual and may be associated with lower bone mass or osteoporosis. The study suggests these factors have a negative impact on bone health, increasing the risk of fractures in postmenopausal years.
The new Guidance emphasizes the importance of early diagnosis and treatment for postmenopausal osteoporosis, citing high fracture rates and low treatment adherence. The report provides updated guidelines for assessing fracture risk, management algorithms, and nutritional recommendations to prevent fractures.
Scientists at Michigan State University found that a natural probiotic supplement can enhance bone density in male mice, but not female mice. The study suggests a possible new treatment for osteoporosis without the risks of traditional medications.
Researchers found that higher dairy intake, particularly from milk and yogurt, is associated with improved bone mineral density in the hip. However, cream consumption was linked to lower bone density. The study suggests choosing low-fat dairy products can increase nutrient intake and reduce saturated fat consumption.
Five young investigators from the Asia-Pacific region were awarded prestigious grants for their top-ranking abstracts. The IOF Young Investigator Award valued at USD 1,000 and invited them to present their work in oral presentations during a special plenary session.
Researchers found that Vietnamese women who received nutrition education counselling showed significant increases in calcium intake and stable bone mass. In contrast, the control group experienced decreased bone mass. The study suggests community-based education programmes can improve bone health in postmenopausal women.
A new study reveals how tiny holes in bones can weaken them, but also shows that strengthening osteocalcin could lead to stronger bones. Researchers suggest that increasing vitamin K intake through foods like spinach and broccoli may help prevent bone fractures.
Researchers found that teenage girls who smoke accumulate less bone during a critical growth period and carry a higher risk of developing osteoporosis later in life. The study suggests that strategies to help prevent osteoporosis should focus on preventing smoking, particularly among adolescent girls.
A genetic variation in the vitamin D receptor has been linked to a decreased risk of developing osteoporosis, according to a meta-analysis of 26 studies. The study suggests that individuals with this variation may have a significantly lower risk of bone mineral density loss.
A new study from Karolinska Institutet in Sweden suggests that digital X-ray radiogrammetry (DXR) used on standard hand radiographs can help identify patients at higher risk of hip fracture. DXR is a technique comparable to more costly methods and may be used preventively to identify people at risk for osteoporosis.
A new health-economic model shows that increasing dairy food consumption can prevent osteoporotic fractures and reduce healthcare costs. The study found that France, Sweden, and the Netherlands could potentially save millions of euros in healthcare costs by boosting dietary calcium intake.
A study by University of Alberta researchers found that providing educational information to physicians and patients improved osteoporosis treatment rates. The intervention led to a significant increase in follow-up testing and treatment, especially among men who are often overlooked as having the condition.
A new approach for assessing fracture risk combines bone density measures with body size and bone size, predicting risk accurately regardless of race or ethnicity. The study found that this composite bone strength index performed just as well as traditional methods in a group of nearly 2,000 women.
A new report by IOF calls for the implementation of coordinator-based post-fracture care to prevent secondary fractures. The report highlights a significant care gap in diagnosing osteoporosis and assessing falls risk among fracture patients.
A new report by the International Osteoporosis Foundation highlights the alarming rate of unaddressed osteoporosis and related falls in clinics and hospitals worldwide. The 'Capture the Fracture' campaign urges concerted global efforts to implement proven models of care, aiming to break the cycle of secondary fractures.
Researchers at Mount Sinai School of Medicine have shown that large doses of vitamin C can stimulate bone formation and prevent bone loss in animal models. The study suggests that vitamin C may be a promising therapeutic agent for treating osteoporosis, particularly in developing nations where treatment options are limited.
Researchers have developed a new computerized technique to diagnose osteoporosis using X-rays, which estimates bone porosity and improves accuracy over visual examination. The system has shown high accuracy rates of less than 2% in detecting osteoporosis in elderly Asian patients.
The International Osteoporosis Foundation (IOF) presented annual Young Investigator Awards to top five ranking abstracts at its regional meeting. The award recipients received USD 1,000 and were invited to present their work during a special plenary session.
The International Osteoporosis Foundation has published new guidelines to help doctors assess treatment efficacy in patients who experience a fracture while on medication for osteoporosis. The guidelines outline a checklist of pragmatic criteria that can be used to define treatment failure and take appropriate action.
A new study suggests that a dual-action polyclonal antibody may offer more effective protection against osteoporosis by slowing bone destruction and building bone. This novel approach has the potential to be safer than existing treatments.
A new study published in the Journal of Clinical Endocrinology and Metabolism found that even minor physical activity can benefit bone health in premenopausal women by reducing sclerostin and enhancing IGF-1 levels. The study involved 1,235 premenopausal women who were followed for eight weeks, with those engaging in more than two hour...
Researchers have identified two related oncogenes, FAM83A and B, which enable breast cancer cells to survive treatment with EGFR TKIs. Expression of these genes in human tumors is correlated with decreased overall survival.
Researchers found that cigarette smoke produces large amounts of two proteins that stimulate the production of osteoclasts, cells responsible for breaking down old bone. This process weakens bones and increases the risk of fractures and disability among older people.
A task force report calls for routine osteoporosis testing and medication treatment for all adults over 50 who experience a fracture, with the goal of reducing hip fractures by 20% by 2020. Fracture liaison services have been shown to significantly improve follow-up assessment and treatment, reducing repeat occurrences.
A new study suggests that moderate drinking as part of a healthy lifestyle may benefit postmenopausal women's bone health by reducing the risk of osteoporosis. The researchers found an increase in blood markers of bone turnover after just two weeks of abstinence, but this effect reversed shortly after resumption of normal drinking habits.
Researchers found two key epigenetic regulating genes that govern cell-fate determination of human bone marrow stem cells. The discovery may allow stem cells to differentiate specifically into bone cells while inhibiting fat cell differentiation, paving the way for therapies in regenerative medicine and osteoporosis treatment.
New research finds that epilepsy patients taking antiepileptic drugs are up to four times more likely to suffer fractures and have osteoporosis compared to non-users. The study also showed a significant increase in falls among female patients taking the medication.
The International Osteoporosis Foundation provides guidance on screening strategies for osteoporosis in young adults, emphasizing the need for caution in diagnosis and treatment. The review highlights the importance of distinguishing between low bone mass and skeletal fragility in this age group.
The Endocrine Society has released new clinical practice guidelines for managing osteoporosis in men, highlighting the importance of bone density testing for those at risk. The guidelines estimate that one in five men aged 50 will experience an osteoporosis-related fracture in their lifetime, with mortality rates higher in men than women.
The International Osteoporosis Foundation reports a significant increase in osteoporosis-related fractures and diagnoses in Latin America, driven by the region's aging population. The projected rise in fragility fractures poses a substantial socio-economic burden on healthcare systems.
The International Osteoporosis Foundation predicts a significant rise in hip fractures in Brazil, projected to increase by 32% by 2050. This is largely attributed to the aging of the Brazilian population, with over 37% expected to be over 50 years old and 14% over 70 years old by then.
A recent study found that male patients with pulmonary disease have a very high risk of osteopenia/osteoporosis, which can be reduced by routine screening and early intervention. The study included 46 patients, most of whom were male, and showed that those with more severe lung disease are more likely to also have bone disease.
A study reevaluating the long-term effects of alendronate on bone fractures found that patients with low bone density at high risk of spine fractures can benefit from continuing therapy. However, for other types of fractures, there is limited data on continued treatment benefits.
The American Society for Bone and Mineral Research (ASBMR) emphasizes the need for further research to improve treatment guidelines for osteoporosis patients taking bisphosphonates. The organization suggests that more research is necessary to determine the optimal length of therapy, as current recommendations may not be suitable for al...
A large-scale study found that young men who engaged in load-bearing sports for four hours a week or more increased bone mass and gained larger bones compared to sedentary individuals. This is thought to offer protection against osteoporosis, which affects men and women alike, leading to porous and weak bones that fracture over time.
Researchers identified 56 genetic regions controlling bone density and found 14 variants increasing fracture risk in women. The study, involving 80,000 participants, reveals a significant link between genetic variations and osteoporosis.
Researchers at the University of Sheffield have identified three new ways to tackle bone diseases like osteoporosis. By understanding how individual cells respond to mechanical loading and stress, they've discovered that controlling ATP release during exercise could help build stronger bones.
Researchers have identified 32 previously unidentified genetic regions associated with osteoporosis and fracture, suggesting the combined contributions of dozens of genes. The study also highlights the complexity of the genetic architecture of disease and the need for larger studies to identify genes important in disease.
Hebrew SeniorLife researchers have identified 56 genetic variants associated with osteoporosis and bone mineral density. The study found that these variants can increase the risk of bone fractures, with women over 65 facing a higher risk. The findings may lead to personalized gene-based treatments for osteoporosis.