Articles tagged with Osteoporosis
Professor Socrates Papapoulos has made significant contributions to advancing osteoporosis research and advocacy worldwide. He is a renowned researcher at the Leiden University Medical Center and IOF Board member, with over 300 publications and several awards.
Professor Harry Genant has been recognized with the first IOF Olof Johnell Science Award for his influential work in noninvasive imaging methods, clinical advances, and best practice guidelines. He is a distinguished researcher, author, and educator, with extensive contributions to bone science and policy implementation.
A Kaiser Permanente study found that nearly 30% of women with osteoporosis fail to pick up their bisphosphonate prescriptions within 60 days. The study identified patient and physician characteristics, such as age, emergency department utilization, and prescription medication use, that contribute to nonadherence.
A recent study found that zoledronic acid, a common osteoporosis drug, not only slows bone loss but also increases levels of sclerostin, a biomarker that inhibits bone formation. This suggests that combination treatments may be needed to effectively treat osteoporosis and increase bone mass.
Professor Maria Luisa Brandi was awarded the prestigious ESCEO-IOF Servier Pierre D. Delmas Prize for her major scientific contributions to bone and mineral diseases. She is a renowned researcher with numerous patents and publications, recognized nationally and internationally.
The European Union faces a significant burden of osteoporosis, with 22 million women and 5.5 million men affected. The annual economic cost of new and prior fragility fractures is €37 billion, with costs expected to increase by 25% by 2025.
Dr. Mary Bouxsein has been recognized with the ESCEO-IOF Herbert Fleisch Medal for her outstanding contributions to understanding skeletal fragility through biomechanics. Her work focuses on predicting fracture risk using novel non-invasive imaging techniques.
A recent study found that simple educational strategies targeting doctors and patients after a fracture significantly improved osteoporosis testing rates, reducing fractures by two fewer per 1,000 patients. Mail-based notice interventions were effective and cost-efficient, with projected savings of $18,000 for every 1,000 patients.
A new EU scorecard highlights significant inequalities in osteoporosis care across European countries. Despite marked differences in fracture risk and services, approximately 57% of high-risk individuals remain untreated, with inadequate access to testing, treatment, and effective medications.
Researchers found that smoking and depressive symptoms in adolescent girls negatively impact bone accrual and may be associated with lower bone mass or osteoporosis. The study suggests these factors have a negative impact on bone health, increasing the risk of fractures in postmenopausal years.
The new Guidance emphasizes the importance of early diagnosis and treatment for postmenopausal osteoporosis, citing high fracture rates and low treatment adherence. The report provides updated guidelines for assessing fracture risk, management algorithms, and nutritional recommendations to prevent fractures.
Scientists at Michigan State University found that a natural probiotic supplement can enhance bone density in male mice, but not female mice. The study suggests a possible new treatment for osteoporosis without the risks of traditional medications.
Researchers found that higher dairy intake, particularly from milk and yogurt, is associated with improved bone mineral density in the hip. However, cream consumption was linked to lower bone density. The study suggests choosing low-fat dairy products can increase nutrient intake and reduce saturated fat consumption.
Five young investigators from the Asia-Pacific region were awarded prestigious grants for their top-ranking abstracts. The IOF Young Investigator Award valued at USD 1,000 and invited them to present their work in oral presentations during a special plenary session.
Researchers found that Vietnamese women who received nutrition education counselling showed significant increases in calcium intake and stable bone mass. In contrast, the control group experienced decreased bone mass. The study suggests community-based education programmes can improve bone health in postmenopausal women.
A new study reveals how tiny holes in bones can weaken them, but also shows that strengthening osteocalcin could lead to stronger bones. Researchers suggest that increasing vitamin K intake through foods like spinach and broccoli may help prevent bone fractures.
Researchers found that teenage girls who smoke accumulate less bone during a critical growth period and carry a higher risk of developing osteoporosis later in life. The study suggests that strategies to help prevent osteoporosis should focus on preventing smoking, particularly among adolescent girls.
A genetic variation in the vitamin D receptor has been linked to a decreased risk of developing osteoporosis, according to a meta-analysis of 26 studies. The study suggests that individuals with this variation may have a significantly lower risk of bone mineral density loss.
A new study from Karolinska Institutet in Sweden suggests that digital X-ray radiogrammetry (DXR) used on standard hand radiographs can help identify patients at higher risk of hip fracture. DXR is a technique comparable to more costly methods and may be used preventively to identify people at risk for osteoporosis.
A new health-economic model shows that increasing dairy food consumption can prevent osteoporotic fractures and reduce healthcare costs. The study found that France, Sweden, and the Netherlands could potentially save millions of euros in healthcare costs by boosting dietary calcium intake.
A study by University of Alberta researchers found that providing educational information to physicians and patients improved osteoporosis treatment rates. The intervention led to a significant increase in follow-up testing and treatment, especially among men who are often overlooked as having the condition.
A new report by IOF calls for the implementation of coordinator-based post-fracture care to prevent secondary fractures. The report highlights a significant care gap in diagnosing osteoporosis and assessing falls risk among fracture patients.
A new approach for assessing fracture risk combines bone density measures with body size and bone size, predicting risk accurately regardless of race or ethnicity. The study found that this composite bone strength index performed just as well as traditional methods in a group of nearly 2,000 women.
A new report by the International Osteoporosis Foundation highlights the alarming rate of unaddressed osteoporosis and related falls in clinics and hospitals worldwide. The 'Capture the Fracture' campaign urges concerted global efforts to implement proven models of care, aiming to break the cycle of secondary fractures.
Researchers at Mount Sinai School of Medicine have shown that large doses of vitamin C can stimulate bone formation and prevent bone loss in animal models. The study suggests that vitamin C may be a promising therapeutic agent for treating osteoporosis, particularly in developing nations where treatment options are limited.
Researchers have developed a new computerized technique to diagnose osteoporosis using X-rays, which estimates bone porosity and improves accuracy over visual examination. The system has shown high accuracy rates of less than 2% in detecting osteoporosis in elderly Asian patients.
The International Osteoporosis Foundation (IOF) presented annual Young Investigator Awards to top five ranking abstracts at its regional meeting. The award recipients received USD 1,000 and were invited to present their work during a special plenary session.
The International Osteoporosis Foundation has published new guidelines to help doctors assess treatment efficacy in patients who experience a fracture while on medication for osteoporosis. The guidelines outline a checklist of pragmatic criteria that can be used to define treatment failure and take appropriate action.
A new study suggests that a dual-action polyclonal antibody may offer more effective protection against osteoporosis by slowing bone destruction and building bone. This novel approach has the potential to be safer than existing treatments.
A new study published in the Journal of Clinical Endocrinology and Metabolism found that even minor physical activity can benefit bone health in premenopausal women by reducing sclerostin and enhancing IGF-1 levels. The study involved 1,235 premenopausal women who were followed for eight weeks, with those engaging in more than two hour...
Researchers have identified two related oncogenes, FAM83A and B, which enable breast cancer cells to survive treatment with EGFR TKIs. Expression of these genes in human tumors is correlated with decreased overall survival.
A task force report calls for routine osteoporosis testing and medication treatment for all adults over 50 who experience a fracture, with the goal of reducing hip fractures by 20% by 2020. Fracture liaison services have been shown to significantly improve follow-up assessment and treatment, reducing repeat occurrences.
Researchers found that cigarette smoke produces large amounts of two proteins that stimulate the production of osteoclasts, cells responsible for breaking down old bone. This process weakens bones and increases the risk of fractures and disability among older people.
A new study suggests that moderate drinking as part of a healthy lifestyle may benefit postmenopausal women's bone health by reducing the risk of osteoporosis. The researchers found an increase in blood markers of bone turnover after just two weeks of abstinence, but this effect reversed shortly after resumption of normal drinking habits.
Researchers found two key epigenetic regulating genes that govern cell-fate determination of human bone marrow stem cells. The discovery may allow stem cells to differentiate specifically into bone cells while inhibiting fat cell differentiation, paving the way for therapies in regenerative medicine and osteoporosis treatment.
New research finds that epilepsy patients taking antiepileptic drugs are up to four times more likely to suffer fractures and have osteoporosis compared to non-users. The study also showed a significant increase in falls among female patients taking the medication.
The International Osteoporosis Foundation provides guidance on screening strategies for osteoporosis in young adults, emphasizing the need for caution in diagnosis and treatment. The review highlights the importance of distinguishing between low bone mass and skeletal fragility in this age group.
The Endocrine Society has released new clinical practice guidelines for managing osteoporosis in men, highlighting the importance of bone density testing for those at risk. The guidelines estimate that one in five men aged 50 will experience an osteoporosis-related fracture in their lifetime, with mortality rates higher in men than women.
The International Osteoporosis Foundation predicts a significant rise in hip fractures in Brazil, projected to increase by 32% by 2050. This is largely attributed to the aging of the Brazilian population, with over 37% expected to be over 50 years old and 14% over 70 years old by then.
The International Osteoporosis Foundation reports a significant increase in osteoporosis-related fractures and diagnoses in Latin America, driven by the region's aging population. The projected rise in fragility fractures poses a substantial socio-economic burden on healthcare systems.
A recent study found that male patients with pulmonary disease have a very high risk of osteopenia/osteoporosis, which can be reduced by routine screening and early intervention. The study included 46 patients, most of whom were male, and showed that those with more severe lung disease are more likely to also have bone disease.
The American Society for Bone and Mineral Research (ASBMR) emphasizes the need for further research to improve treatment guidelines for osteoporosis patients taking bisphosphonates. The organization suggests that more research is necessary to determine the optimal length of therapy, as current recommendations may not be suitable for al...
A study reevaluating the long-term effects of alendronate on bone fractures found that patients with low bone density at high risk of spine fractures can benefit from continuing therapy. However, for other types of fractures, there is limited data on continued treatment benefits.
A large-scale study found that young men who engaged in load-bearing sports for four hours a week or more increased bone mass and gained larger bones compared to sedentary individuals. This is thought to offer protection against osteoporosis, which affects men and women alike, leading to porous and weak bones that fracture over time.
Researchers identified 56 genetic regions controlling bone density and found 14 variants increasing fracture risk in women. The study, involving 80,000 participants, reveals a significant link between genetic variations and osteoporosis.
Researchers at the University of Sheffield have identified three new ways to tackle bone diseases like osteoporosis. By understanding how individual cells respond to mechanical loading and stress, they've discovered that controlling ATP release during exercise could help build stronger bones.
Hebrew SeniorLife researchers have identified 56 genetic variants associated with osteoporosis and bone mineral density. The study found that these variants can increase the risk of bone fractures, with women over 65 facing a higher risk. The findings may lead to personalized gene-based treatments for osteoporosis.
Researchers have identified 32 previously unidentified genetic regions associated with osteoporosis and fracture, suggesting the combined contributions of dozens of genes. The study also highlights the complexity of the genetic architecture of disease and the need for larger studies to identify genes important in disease.
Common osteoporosis medications may increase the risk of scleritis and uveitis, two inflammatory eye diseases that can severely impact vision. First-time users of oral bisphosphonates are at a higher risk compared to non-users.
The International Osteoporosis Foundation (IOF) and the European Calcified Tissue Society (ECTS) have published a guidance document outlining management strategies to prevent bone loss and related fractures in high-risk patients. The guidelines provide a framework for developing national assessment and treatment guidelines, emphasizing...
Long-term oral glucocorticoid therapy is associated with a significant risk of bone loss and fractures, particularly in older adults and those with higher doses. To mitigate this risk, patients should take preventive measures such as maintaining adequate calcium and protein intake, exercising regularly, and getting enough vitamin D.
Research suggests that early growth in the womb and first few years of life is positively related to total hip bone size and mineral content. Stronger hips can protect against future hip fractures, leading to optimized early growth strategies to reduce osteoporotic fracture risk.
The grant will support research on the relationships between body composition, muscle and bone strength. Dr Edwards' project aims to clarify uncertainties with regard to these relationships and assess their impact on fracture risk.
Professor Cyrus Cooper was awarded the IOF Medal of Achievement for advancing knowledge of osteoporosis through original and outstanding scientific contributions. He has led research programs on epidemiology, bone mineral accrual, and preventive strategies against hip fracture.
A new study has found a significant variation in hip fracture risk across the globe, with countries experiencing a 10-fold difference in incidence rates. The study's findings indicate that higher risk countries for both men and women are located in North Western and Central Europe.
Dr. Claus Christiansen received the ESCEO-IOF Medal for his groundbreaking work on calcium metabolism in postmenopausal women. He has published extensively over 900 articles and book chapters, and has been a leading figure in osteoporosis research for over three decades.
René Rizzoli receives the award for his major scientific contributions to osteoporosis research and advocacy. He is recognized for both his clinical achievements and long-term impact as an educator and advocate in the field.
Researchers at the Academy of Finland have developed a new, laser-based ultrasound technique to accurately assess osteoporosis. This method uses photo-acoustic methods to produce an ultrasound pulse that propagates along the bone, providing a more accurate measurement than current X-ray methods.
Osteoporosis experts advocate for shorter intervals between DXA scans for high-risk women, patients with low bone mineral density, and those receiving osteoporosis medication. This approach can prevent debilitating fractures and reduce healthcare costs.
The clinical guide highlights the benefits of selective estrogen receptor modulators (SERMs) in reducing fracture risk for postmenopausal women. SERMs, such as bazedoxifene and lasofoxifene, offer a new therapeutic option with potential anti-fracture effects.