Articles tagged with Osteoporosis
Researchers used ECIS to track stem cell transformation into bone tissue cells, revealing age-related differences in conversion rates and calcium secretion. The study provides new insights into the potential of adipose-derived stem cells for osteoporosis treatment.
Scientists at University of Würzburg have crystallized an antibody effective against Sclerostin, a protein involved in bone metabolism. The findings offer a promising treatment option for osteoporosis, a condition that affects elderly women and increases the risk of fractures.
The systematic review concludes that fixed or age-dependent thresholds are more effective in identifying individuals at high risk of fracture than the use of bone mineral density (BMD) values alone. However, intervention thresholds must be country-specific, according to the report.
A new study published in JAMA found that daily injection of the drug abaloparatide significantly reduced the risk of new vertebral and nonvertebral fractures in postmenopausal women with osteoporosis. The treatment also showed a more pronounced anabolic effect on bone compared to other osteoporosis drugs.
Research by University of North Texas historian Constance Hilliard reveals that West African women living in regions without dairy farming have a lower rate of postmenopausal hip fractures caused by osteoporosis than their East African peers. This paradox is due to genetic adaptation to low-calcium diets, which disadvantage bone strength.
A new review published by the IFCC-IOF Working Group for Standardisation of Bone Marker Assays supports the potential for bone turnover markers to provide clinically useful information. The study highlights the importance of standardization and harmonization of units for reporting serum/plasma CTX and PINP concentrations.
Researchers at the University of Nottingham have secured £1.2m to develop injectable stem cell-carrying materials to treat osteoporosis and other bone-thinning diseases. The targeted therapy aims to promote bone regeneration through a quick, easy, and minimally-invasive treatment.
Elderly patients with wrist fractures are more likely to have poor balance, increasing the risk of future injuries. Researchers recommend evaluating and treating balance deficiencies after a fracture to prevent further complications.
High-risk osteoporosis patients often underdiagnosed and undertreated, despite effective fracture-preventing medications. The authors call for improved diagnosis and therapy to prevent fractures in this high-risk population.
A recent study found that approximately one-third of women taking oral bisphosphonates continue to be at elevated risk for bone fracture. Despite the medication being effective in reducing fracture risk, various factors such as other medical conditions and fall-related problems contribute to this increased risk.
A survey by Northwell Health found that nearly 7 in 10 older adults with hip fractures are not informed about osteoporosis, despite the disease being a common cause of hip fractures. The study suggests that improved education and treatment for osteoporosis could reduce re-fracture rates and improve patient outcomes.
A new analysis suggests that the moderate effect of calcium and vitamin D on fracture prevention is not large enough to outweigh the potential increased risk of cardiovascular disease. For 65-year-old women at low risk of bone fracture, the risks may outweigh the benefits.
A consensus report from the International Osteoporosis Foundation Fracture Working Group recommends that patients with recent fractures should start osteoporosis medications as soon as possible. The panel agreed that anabolic agents like teriparatide may have a beneficial effect on fracture healing, while bisphosphonates may delay it.
Professor Eugene McCloskey was recognized for his significant advancements in vertebral fracture definition, osteoporosis epidemiology, and non-invasive assessments of bone strength. He has contributed to the development of the FRAX tool and published over 250 peer-reviewed publications.
The IOF-ESCEO 2016 Pierre Meunier Young Scientist Awards were presented to Professors Elaine Dennison and Olivier Bruyère for their exceptional research on musculoskeletal ageing, osteoporosis, and osteoarthritis. The awards recognize their potential to become key opinion leaders in the field.
Professor Serge Ferrari has been recognized with the International Osteoporosis Foundation's 2016 Olof Johnell Science Award for his significant work in bone health, genetics of osteoporosis, and bone remodeling. He is a leading thought leader in the field, known for translating new research findings into improved patient care.
Dr. Elias Hanna Saba, Chief Executive Director of the Palestinian Osteoporosis Prevention Society, was awarded the International Osteoporosis Foundation's Committee of National Societies Medal for his over 26 years of experience in bone and muscle health and patient education. The medal recognizes his dedication to expanding IOF's mess...
A new study found that the risk of a second major osteoporotic fracture increases by 4% for each year of age and is 41% higher in women than men. The risk of subsequent fractures decreases over time, but remains elevated throughout follow-up.
A recent study reveals that sarcopenia is expected to significantly increase in Europe, affecting up to 19 million seniors. The prevalence of sarcopenia will rise from 11.1% in 2016 to 12.9% by 2045, with women accounting for a majority of cases.
A study by UK and Swedish researchers found that male Swedish farmers have a significantly lower risk of hip fracture, possibly due to their high levels of physical activity. The researchers analyzed data from Sweden's national registry and found that farming was associated with a 39% lower risk of hip fracture.
Research shows that patients with total knee replacement due to primary osteoarthritis have a low risk of hip and vertebral fractures before and after surgery. However, the risk increases by 19% for vertebral fracture and 4% for hip fracture in the years following surgery.
The IOF President's Award was presented to eight leading regional osteoporosis experts and advocates for their contributions to global osteoporosis awareness and education. The recipients were recognized for their outstanding work in the field, including Dr Ambrish Mithal, Prof Patricia Clark, and Prof Jorge Cannata Andia.
A UK study found no link between calcium supplementation, with or without vitamin D, and hospital admissions or mortality due to cardiovascular events. The analysis of the UK Biobank dataset showed that calcium supplementation did not increase the risk of future cardiac events.
Professor René Rizzoli, a leading Swiss investigator, has been awarded the ESCEO-IOF Medal for his groundbreaking work in basic bone science. The medal recognizes his contributions to understanding bone and mineral metabolism, with over 800 publications to his name.
Professor John A. Kanis has made significant contributions to advances in the field of osteoporosis and musculoskeletal disorders. He is the author of over 1200 papers, chapters, and books on bone disease and metabolism.
Researchers have identified new molecular targets for treating musculoskeletal diseases such as sarcopenia and osteoporosis. Several promising treatment options are expected to be available in the near future.
A recent study found that surgery to remove overactive parathyroid glands is associated with significantly fewer bone fractures compared to treatment with bisphosphonate medications. This suggests that medication may not be the most effective option for treating hyperparathyroidism, which is a leading cause of osteoporosis.
A new study found that abaloparatide-SC increased bone mineral density in the spine and hip, reducing the risk of vertebral and nonvertebral fractures. The treatment also showed promise in a broad range of postmenopausal women with osteoporosis, regardless of baseline patient characteristics.
A study published in STEM CELLS Translational Medicine found that stem cell therapy can restore normal bone structure in mice with age-related osteoporosis. The treatment involves injecting healthy mesenchymal stem cells into the mice, which can then produce new bone tissue.
Men with fertility problems are at higher risk of metabolic diseases such as osteoporosis and diabetes. Researchers found that one-third of infertile men under 50 have biochemical signs of low sex hormone levels, which can lead to fractures and increased glucose levels.
Osteoporosis medications bisphosphonates have significantly reduced fracture risks but also increase the risk of atypical femur fractures. Treatment involves stopping the drug and supplementing with calcium and vitamin D.
A randomized controlled trial found that physical therapy significantly improves urinary incontinence in postmenopausal women with osteoporosis, reducing urine leaks by 75%. The treatment involved pelvic floor muscle exercise and retraining with biofeedback.
Research highlights early life factors influencing osteoporosis risk, emphasizing importance of prevention throughout life course. Early growth and nutrition play significant roles in determining bone mass and density.
A new report by a Task Force of the American Society for Bone and Mineral Research suggests that clinicians should reassess osteoporosis medication use after 5 years. Periodic evaluation and monitoring are key to weighing benefits and risks.
The International Osteoporosis Foundation is urging physicians to individualize treatment decisions based on patients' fracture risk, rather than automatically interrupting or stopping bisphosphonate therapy. The benefits of continued therapy in high-risk patients greatly exceed the risk of rare side effects.
Experts presented research on the complex relationship between diabetes and bone, highlighting increased risk of fragility fractures in people with type 2 diabetes. The studies found that diabetic patients may experience higher BMD but lower bone microstructure quality, leading to an increased risk of wrist fracture.
Research studies presented at the IOF regional meeting found significantly low levels of vitamin D in different population groups across the Middle East. The studies revealed high prevalence of vitamin D deficiency, affecting all age groups, sexes and local/non-local populations.
The IOF Young Investigator Research Award is offered to researchers aged 40 years or younger. The award includes a grant of 1000 USD and the opportunity to present at a special oral session during the Meeting.
A preliminary study found that soy protein and isoflavones can slow down bone loss and lower the risk of osteoporosis in early menopause. The study suggests that incorporating soy foods into a diet could be an effective option for improving bone health in women during this period.
Researchers from National Research Tomsk State University found that mammoths suffered from skeletal diseases due to chronic mineral hunger, leading to high traumatism and eventual extinction. The study suggests that geochemical stress caused by acidic landscapes may have played a crucial role in the demise of these majestic creatures.
A new study finds that low-weight, high-repetition resistance training increases bone mineral density in adults, with significant gains observed in osteopenic and postmenopausal individuals. The exercise regimen is a feasible option for older and inactive adults, and may help prevent hip fractures.
A study found that greater neighborhood access to fast-food outlets is associated with poorer bone development in early childhood, while increased exposure to healthy specialty stores is linked to higher bone mass. The research suggests that improving the food environment could optimize childhood bone development.
A new review emphasizes the significance of nutrition throughout life for maintaining a healthy skeleton, particularly in children and seniors who are at risk of osteoporosis. The study finds that adequate intake of calcium, vitamin D, and protein can help prevent premature bone loss and fractures.
The Hungarian Osteoporosis Prevention Society has been recognized for its exceptional efforts in promoting osteoporosis awareness and prevention, as well as supporting patients through various initiatives. The award acknowledges the society's commitment to reducing falls and osteoporotic fractures among the Hungarian population.
A study projects that over 319 million people will be at high risk of fracture by 2040, doubling the current number. This increase is expected in all regions, but particularly marked in Africa and Latin America, with Asia bearing the highest proportion of the global burden.
The new guideline focuses on preventing fractures among frail seniors, highlighting the importance of nutrition, exercise, and medication adherence. It also emphasizes the need for individually tailored interventions to reduce falls and promotes safe living environments.
A statewide study in Indiana found that fewer than a quarter of men and women with osteoporosis or fragility fracture received treatment between 2005 and 2012. The study also found disparities in treatment rates among different groups, including racial and ethnic minorities and individuals with multiple chronic conditions.
An international research team has identified a novel gene, EN1, associated with osteoporosis and bone mineral density. The study used extensive genetic data from the UK10K project to uncover a genetic variant near EN1 with the strongest effect on BMD and fracture.
A decade-long study shows growth hormone continues to reduce fracture risk and maintain bone density in postmenopausal women with osteoporosis. The treatment's effects were found to last for years after it was administered.
Doctors warn that commercial interests are driving the continued recommendation of calcium and vitamin D supplements for osteoporosis treatment, despite a lack of evidence showing their benefit. The authors argue that industry influence is fuelling enthusiasm for these supplements, which are highly profitable.
Middle-aged men with low bone mass can improve bone density through exercise-based interventions, such as weight-lifting and jumping programs. These exercises, completed for at least six months, increase bone mass in the whole body and lumbar spine, reducing the risk of osteoporosis.
Researchers found that postmenopausal women with kidney or bladder stones were not at increased risk for osteoporosis, contrary to previous findings in men. Women with a urinary tract stone were more likely to develop a second stone, however.
Researchers discovered a link between heart disease and lower bone mineral density, with women more affected. The study suggests that heart disease may weaken bones, increasing risk of fractures.
A new review by the International Osteoporosis Foundation confirms the success of the Capture the Fracture Best Practice Framework as a single set of quality standards for Fracture Liaison Services globally. The framework helps raise standards, reinforces international guidelines, and identifies common challenges faced by FLS worldwide.
A drug already FDA-approved for osteoporosis has been found to stimulate the production of cells controlling insulin balance in diabetic mice. This could lead to a potential new treatment for type 2 diabetes.
A comprehensive classification of rare genetic metabolic bone disorders has been developed, categorizing them into four major groups based on their metabolic pathway. This taxonomy provides valuable information for diagnosis, genetic testing, and the development of orphan drugs.
Use of bisphosphonates declined by 50% from 2008 to 2012 following media reports on rare fractures. The study published in Journal of Bone and Mineral Research reveals a dramatic drop in osteoporosis medication use.
A recent study found that one in four men over 50 will break a bone due to osteoporosis, surpassing prostate cancer incidence rates. The research suggests adding men to osteoporosis screening guidelines to address the high likelihood of vertebral fractures and low bone density.
A study found that osteoporosis screening rates increased among women at age 50, despite guidelines suggesting screening at age 65 unless risk factors are present. The presence of risk factors had a modest influence on screening decisions.
Up to 2 million American men suffer from osteoporosis, with worse health outcomes than women. Despite the severity of osteoporosis in men, fewer take preventive measures or undergo screening.