Articles tagged with Osteoporosis
A new study found that abaloparatide-SC increased bone mineral density in the spine and hip, reducing the risk of vertebral and nonvertebral fractures. The treatment also showed promise in a broad range of postmenopausal women with osteoporosis, regardless of baseline patient characteristics.
A study published in STEM CELLS Translational Medicine found that stem cell therapy can restore normal bone structure in mice with age-related osteoporosis. The treatment involves injecting healthy mesenchymal stem cells into the mice, which can then produce new bone tissue.
Men with fertility problems are at higher risk of metabolic diseases such as osteoporosis and diabetes. Researchers found that one-third of infertile men under 50 have biochemical signs of low sex hormone levels, which can lead to fractures and increased glucose levels.
Osteoporosis medications bisphosphonates have significantly reduced fracture risks but also increase the risk of atypical femur fractures. Treatment involves stopping the drug and supplementing with calcium and vitamin D.
A randomized controlled trial found that physical therapy significantly improves urinary incontinence in postmenopausal women with osteoporosis, reducing urine leaks by 75%. The treatment involved pelvic floor muscle exercise and retraining with biofeedback.
Research highlights early life factors influencing osteoporosis risk, emphasizing importance of prevention throughout life course. Early growth and nutrition play significant roles in determining bone mass and density.
A new report by a Task Force of the American Society for Bone and Mineral Research suggests that clinicians should reassess osteoporosis medication use after 5 years. Periodic evaluation and monitoring are key to weighing benefits and risks.
The International Osteoporosis Foundation is urging physicians to individualize treatment decisions based on patients' fracture risk, rather than automatically interrupting or stopping bisphosphonate therapy. The benefits of continued therapy in high-risk patients greatly exceed the risk of rare side effects.
Research studies presented at the IOF regional meeting found significantly low levels of vitamin D in different population groups across the Middle East. The studies revealed high prevalence of vitamin D deficiency, affecting all age groups, sexes and local/non-local populations.
Experts presented research on the complex relationship between diabetes and bone, highlighting increased risk of fragility fractures in people with type 2 diabetes. The studies found that diabetic patients may experience higher BMD but lower bone microstructure quality, leading to an increased risk of wrist fracture.
The IOF Young Investigator Research Award is offered to researchers aged 40 years or younger. The award includes a grant of 1000 USD and the opportunity to present at a special oral session during the Meeting.
A preliminary study found that soy protein and isoflavones can slow down bone loss and lower the risk of osteoporosis in early menopause. The study suggests that incorporating soy foods into a diet could be an effective option for improving bone health in women during this period.
Researchers from National Research Tomsk State University found that mammoths suffered from skeletal diseases due to chronic mineral hunger, leading to high traumatism and eventual extinction. The study suggests that geochemical stress caused by acidic landscapes may have played a crucial role in the demise of these majestic creatures.
A new study finds that low-weight, high-repetition resistance training increases bone mineral density in adults, with significant gains observed in osteopenic and postmenopausal individuals. The exercise regimen is a feasible option for older and inactive adults, and may help prevent hip fractures.
A study found that greater neighborhood access to fast-food outlets is associated with poorer bone development in early childhood, while increased exposure to healthy specialty stores is linked to higher bone mass. The research suggests that improving the food environment could optimize childhood bone development.
A new review emphasizes the significance of nutrition throughout life for maintaining a healthy skeleton, particularly in children and seniors who are at risk of osteoporosis. The study finds that adequate intake of calcium, vitamin D, and protein can help prevent premature bone loss and fractures.
A study projects that over 319 million people will be at high risk of fracture by 2040, doubling the current number. This increase is expected in all regions, but particularly marked in Africa and Latin America, with Asia bearing the highest proportion of the global burden.
The Hungarian Osteoporosis Prevention Society has been recognized for its exceptional efforts in promoting osteoporosis awareness and prevention, as well as supporting patients through various initiatives. The award acknowledges the society's commitment to reducing falls and osteoporotic fractures among the Hungarian population.
The new guideline focuses on preventing fractures among frail seniors, highlighting the importance of nutrition, exercise, and medication adherence. It also emphasizes the need for individually tailored interventions to reduce falls and promotes safe living environments.
A statewide study in Indiana found that fewer than a quarter of men and women with osteoporosis or fragility fracture received treatment between 2005 and 2012. The study also found disparities in treatment rates among different groups, including racial and ethnic minorities and individuals with multiple chronic conditions.
An international research team has identified a novel gene, EN1, associated with osteoporosis and bone mineral density. The study used extensive genetic data from the UK10K project to uncover a genetic variant near EN1 with the strongest effect on BMD and fracture.
A decade-long study shows growth hormone continues to reduce fracture risk and maintain bone density in postmenopausal women with osteoporosis. The treatment's effects were found to last for years after it was administered.
Doctors warn that commercial interests are driving the continued recommendation of calcium and vitamin D supplements for osteoporosis treatment, despite a lack of evidence showing their benefit. The authors argue that industry influence is fuelling enthusiasm for these supplements, which are highly profitable.
Middle-aged men with low bone mass can improve bone density through exercise-based interventions, such as weight-lifting and jumping programs. These exercises, completed for at least six months, increase bone mass in the whole body and lumbar spine, reducing the risk of osteoporosis.
Researchers found that postmenopausal women with kidney or bladder stones were not at increased risk for osteoporosis, contrary to previous findings in men. Women with a urinary tract stone were more likely to develop a second stone, however.
Researchers discovered a link between heart disease and lower bone mineral density, with women more affected. The study suggests that heart disease may weaken bones, increasing risk of fractures.
A new review by the International Osteoporosis Foundation confirms the success of the Capture the Fracture Best Practice Framework as a single set of quality standards for Fracture Liaison Services globally. The framework helps raise standards, reinforces international guidelines, and identifies common challenges faced by FLS worldwide.
A drug already FDA-approved for osteoporosis has been found to stimulate the production of cells controlling insulin balance in diabetic mice. This could lead to a potential new treatment for type 2 diabetes.
A comprehensive classification of rare genetic metabolic bone disorders has been developed, categorizing them into four major groups based on their metabolic pathway. This taxonomy provides valuable information for diagnosis, genetic testing, and the development of orphan drugs.
Use of bisphosphonates declined by 50% from 2008 to 2012 following media reports on rare fractures. The study published in Journal of Bone and Mineral Research reveals a dramatic drop in osteoporosis medication use.
A recent study found that one in four men over 50 will break a bone due to osteoporosis, surpassing prostate cancer incidence rates. The research suggests adding men to osteoporosis screening guidelines to address the high likelihood of vertebral fractures and low bone density.
A study found that osteoporosis screening rates increased among women at age 50, despite guidelines suggesting screening at age 65 unless risk factors are present. The presence of risk factors had a modest influence on screening decisions.
Up to 2 million American men suffer from osteoporosis, with worse health outcomes than women. Despite the severity of osteoporosis in men, fewer take preventive measures or undergo screening.
Patients with newly diagnosed and treated osteoporosis have an increased life expectancy of 15-26 years, depending on age and gender. Long-term management of osteoporosis is crucial to ensure optimal patient outcomes.
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that people with osteoporosis are at a 1.76-fold higher risk of developing sudden sensorineural hearing loss. Researchers analyzed medical records of over 10,600 individuals with osteoporosis and found that they were more likely to be diag...
A clinical trial found that zoledronic acid improved bone mineral density and reduced bone turnover in frail elderly women with osteoporosis. The treatment group showed significant increases in hip and spine bone mineral density at 12 and 24 months, while the placebo group showed decreases.
Osteoporosis-related fractures in China are expected to double by 2035, with costs rising to approximately US$25.58 billion by 2050. The study also found that women account for 73% of total costs, sustaining three times more fractures than men.
Sarcopenia, age-related muscle mass and strength loss, lacks a widely accepted clinical definition. A new review aims to develop refined criteria, addressing the need for a consensus definition.
A new study reveals UK hospital costs for hip fractures to be approximately £1.1 billion annually, highlighting the need for preventive measures. Fracture liaison services have been shown to reduce secondary fractures and improve quality of life.
A Canadian study found a significant treatment gap among high-risk patients with prior hip fractures or osteoporosis. The study suggests that those with prior hip fractures are least likely to receive osteoporosis therapy, emphasizing the need for better guidelines and knowledge transfer strategies.
A Swedish study shows that implementing Fracture Liaison Services can prevent a significant number of fractures, saving lives and reducing healthcare costs. The model predicts a reduction in fractures by 50% among patients identified with bone mineral testing, resulting in 19 quality-adjusted life years saved.
A recent study published in Osteoporosis International found that painful knee osteoarthritis in women is associated with a higher risk of early death compared to unaffected women. The study, which followed middle-aged women for 24 years, also found no link between hand osteoarthritis and excess mortality risk.
A phase 3 clinical trial found that abaloparatide reduces the rate of new spinal fractures by 86 percent and also significantly lowers the fracture rate at other parts of the body. The treatment also delays the time to the first nonvertebral fracture and increases bone mineral density.
A large study found that male smokers are more likely to develop osteoporosis and vertebral fractures compared to female smokers. Current guidelines do not recommend osteoporosis screening for men, but the researchers suggest that smokers of both genders should be screened for low bone density.
Recent articles in JBJS publications examine the relationship between bisphosphonates and atypical femoral fractures. Prodromal thigh pain, radiolucent lines on X-rays, and prolonged bisphosphonate use are indicators of an impending fracture. Conservative management with discontinuation and weight-bearing is recommended.
A new DNA vaccine targeting p62 has shown promising results in alleviating chronic inflammation and osteoporosis by exploiting the protein's role in autophagy. The vaccine, currently in phase I clinical trials, may offer a safe treatment for inflammatory bone loss.
New research from the University of Surrey found that potassium salts improve bone health by reducing bone resorption. The study showed a significant decrease in bone resorption and an increase in bone strength, potentially preventing osteoporosis.
A recent study published in Psychosomatic Medicine found that women with good life satisfaction had higher bone density and lower rates of osteoporosis compared to those with poor life satisfaction. Life satisfaction was positively associated with bone health, even after controlling for other risk factors.
A large cohort study found that women experiencing moderate to severe hot flashes and night sweats have lower bone mineral density and higher rates of hip fracture. Women with these symptoms are more likely to have issues with bone health than their peers, highlighting the need for healthy lifestyle habits to prevent osteoporosis.
A study found that prescriptions for bisphosphonates remain low even among men at high risk of fractures on androgen deprivation therapy. The study suggests limited awareness among clinicians about optimal bone health management, particularly in men with prior osteoporosis or fragility fracture.
A large study found no association between rosuvastatin statin therapy and reduced fracture risk in participants with elevated inflammatory biomarkers. Despite potential biological pathways linking cardiovascular disease and osteoporosis, the results contradict previous studies suggesting a protective effect of statins on fractures.
A new study has found that weight loss of 10 percent or more in seniors substantially increases the risk of hip fractures. The Singapore Chinese Health Study found that body weight changes were associated with a significant increase in hip fracture risk, whereas weight gain did not reduce risk significantly.
A recent study forecasts the immense economic cost of osteoporotic fractures in China, expected to double by 2035 and reach $25.58 billion by 2050 due to an aging population.
The International Osteoporosis Foundation has awarded young investigators from four countries for their groundbreaking studies on bone health. Researchers have shed light on the impact of sedentary time, moderate-to-vigorous physical activity, and body weight change on bone strength in adolescent girls.
A study found that older men are three times less likely than women to undergo osteoporosis screening and treatment after a broken wrist. This disparity increases the risk of future bone breaks and related complications in men, who already have twice the mortality rate of women following a hip fracture.
A new study from Beth Israel Deaconess Medical Center found that men with osteoporosis-related fractures are under-screened for bone density testing and treatment. The research highlights the importance of evaluating and treating older men for osteoporosis, as fracture rates among men are expected to increase dramatically by 2050.
The International Osteoporosis Foundation has published a succinct slide deck highlighting 60 original scientific abstracts presented at the ASBMR meeting in September 2014. The slide kit provides clinically focused research on various aspects of bone health, including osteoporosis treatment and new strategies.
A new study found that US osteoporosis screening guidelines failed to identify the majority of younger post-menopausal women who experienced major fractures. The guidelines recommended testing and treatment for women aged 65+, but only predicted fractures in around 25% of those aged 50-64.
The International Osteoporosis Foundation reports that one-third of all hip fractures worldwide occur in men, with mortality rates as high as 37% in the first year following fracture. Millions of men are left vulnerable to early death and disability due to osteoporosis.
A new study reveals that preosteoclasts, a previously overlooked group of cells, play a crucial role in maintaining bone health. The discovery explains the success of an experimental osteoporosis drug and opens up new avenues for research into designing future studies.