Articles tagged with Osteoporosis
Collaboration between physicians and dentists is essential for improving the early detection and treatment of patients with osteoporosis. Oral health maintenance plays a vital role in managing osteoporosis, and healthcare professionals should discuss patient care decisions with the physician.
The American College of Physicians has released a new clinical practice guideline on screening for osteoporosis in men. Osteoporosis is expected to affect nearly 50% more men over the next 15 years due to increasing rates among older adults.
The International Osteoporosis Foundation is urging EU countries to continue seeking government recognition and action to address the growing burden of osteoporosis. Despite progress in management, important care gaps remain, including limited access to bone mineral density machines and evidence-based treatments.
A landmark observational study is tracking the management of osteoporosis in 60,000 postmenopausal women from around the world. The Global Longitudinal Registry of Osteoporosis in Women (GLOW) aims to improve diagnosis and treatment standards, with data collected over five years.
A study published in the Journal of the American Society Nephrology found that raloxifene increases bone mineral density and reduces vertebral fractures in postmenopausal women with mild to moderate chronic kidney disease. The medication is safe and effective for this patient population, reversing bone loss and fracture risk.
A recent study discovered that variants of the LRP5 gene are linked to a significant increase in fracture risk by up to 20 percent and lower levels of bone mineral density, particularly in the spine and hip. The research, conducted on a large-scale evidence base, suggests that genetic factors play a major role in determining bone health.
The International Osteoporosis Foundation (IOF) welcomes the ESCEO European guidance for the diagnosis and management of osteoporosis in postmenopausal women. The guidance provides a roadmap for implementing the new FRAX tool based on the WHO technical report, offering case-finding strategies supported by health economic data.
A recent study published in Osteoporosis International found that up to 50% of postmenopausal women with osteoporosis stop their treatment within a year due to side effects. The study showed that fractures have significant physical, psychological, and social implications on patients' quality of life.
Researchers at Baylor College of Medicine found that Notch stimulates early proliferation of osteoblastic cells responsible for bone formation. However, when Notch function is abolished in these cells, osteoporosis occurs due to an imbalance between bone formation and resorption.
A study of over 7,000 patients found that bisphosphonate therapy for osteoporosis has little to no effect on the risk of bone necrosis. However, clinicians face significant challenges in treating bone necrosis when it presents itself in patients.
Research finds gastric cancer patients post-gastrectomy have high prevalence of osteoporosis (38.3%) and vertebral deformities. Screening by Dual-energy X-ray absorptiometry is recommended for those over 60 or with anemia/back pain.
A specially developed carrot has been produced to help people absorb more calcium, with a net increase in calcium absorption found in humans who ate the carrot. Adding this carrot to the diet can help prevent diseases like osteoporosis.
Researchers at Texas A&M AgriLife's Vegetable and Fruit Improvement Center developed a special carrot to increase calcium absorption in humans. The study found a two-fold increase in calcium intake, which can help prevent diseases like osteoporosis.
Researchers found that oral osteoporosis medications appear to reduce the risk of jaw degradation in patients. The study analyzed medical claims data from over 714,000 individuals and showed a protective association between oral bisphosphonates and adverse bone outcomes.
A bone mineral density test given 15 years earlier predicted a woman's risk of developing fractures to her spine over time. More than half of the women with low BMD and existing spinal fractures developed new fractures over the 15-year study period, highlighting the importance of BMD testing for women over 50.
The International Osteoporosis Foundation (IOF) applauds the National Osteoporosis Society's (NOS) success in appealing the National Institute for Health and Clinical Excellence's (NICE) Guidance on osteoporotic fracture prevention. IOF calls for continued efforts to ensure clinically appropriate treatments are made available.
A 15-year study found women with low bone mineral density and a previous vertebral fracture had a higher risk of new vertebral fractures compared to those with normal bone density and no previous fracture. Women who experienced a new fracture were more likely to have a positive fracture history, weigh less, and report lower estrogen use.
Researchers found a significant relationship between bone mineral density and fracture risk, regardless of trauma severity. Women who experienced high-trauma fractures were at increased risk for future fractures.
A study found that high-trauma nonspine fractures in older women and men are associated with low bone mineral density and an increased risk of a subsequent fracture. The researchers analyzed data from two U.S. studies and found that low bone mineral density was strongly associated with high-trauma nonspine fractures.
Geisinger's rheumatology department redesigned osteoporosis and rheumatoid arthritis care by simplifying the ordering process for bone density scans. As a result, 88% of patients received the scan, compared to 18% previously, with quadrupling the number of patients who underwent testing.
Researchers, led by Liyun Wang, aim to shed light on how osteocytes sense external stimuli and communicate with surface cells. This study may lead to effective drug therapies for treating debilitating bone diseases.
A new study found that Forteo significantly increased bone density measurements, particularly in the lumbar spine and hip, compared to Fosamax. The findings suggest Forteo may be a valuable treatment option for secondary osteoporosis caused by glucocorticoid use.
A Kaiser Permanente study found that electronic medical records and outreach programs significantly improved osteoporosis diagnosis and management in older women. The study, which analyzed data from 3,588 women aged 67 and older, showed a significant increase in bone density screening and osteoporosis medication after a fracture.
A new study from the University of Missouri-Columbia found that men engaging in predominantly low-impact forms of exercise have an increased incidence of osteopenia, a condition resulting in two times the risk of bone fracture. Regular weight-bearing activities can mitigate this risk and maintain healthy bones.
Researchers at Hebrew SeniorLife's Institute for Aging Research have examined nearly 100,000 genetic markers to determine which genes are responsible for osteoporosis and longevity. The studies found associations between specific genetic variants and traits such as bone mineral density and age at death.
Researchers found that universal bone densitometry followed by oral bisphosphonate therapy may be cost-effective for certain older men with or without prior fractures. The study suggested that this strategy could reduce the absolute 10-year incidence of clinical fractures among older men with a prior fracture.
A study by Dr. Michael Holick reveals that vitamin D deficiency is common and problematic, increasing the risk of chronic diseases such as osteopenia, osteoporosis, and certain cancers. The author suggests increasing recommended Adequate Intakes for vitamin D to 800-1000 IU/d.
Researchers found that COPD patients exhibit greater arterial stiffness, especially those with osteoporosis. This early sign of aging may contribute to the increased risk of cardiovascular disease in these patients.
New research reveals that active estrogen metabolites are a strong predictor of bone mineral density in men. Higher levels of these hormones tend to result in higher bone density, while lower levels increase the risk of osteoporosis.
A Phase III clinical study involving over 7,700 women found that Reclast reduced the frequency of all types of osteoporotic bone fractures by 70%, including a significant reduction in spine fractures. Bone mineral density also increased significantly in women on Reclast compared to placebo.
A new study has found that a once-a-year treatment for osteoporosis can be as effective as monthly or weekly regimens at reducing bone fractures. The treatment, zoledronic acid, was shown to reduce the risk of spinal fractures by 70% and hip fractures by 40% over three years.
A study of 372 men with prostate cancer found that 49% had osteoporosis, with those receiving hormone therapy and having undergone radical prostatectomy being at highest risk. The authors suggest that daily calcium intake could be used as a prognostic factor for osteoporosis in these patients.
A retrospective analysis found patients taking risedronate (Actonel) had a lower incidence of hip fractures compared to those taking alendronate. The REAL study used a health service utilization database and provided valuable insights into the clinical effectiveness of these osteoporosis treatments.
The National Institute of Clinical Studies (NICS) has awarded six Fellowships to support the development of experts and leaders in evidence implementation. The fellows will work on projects addressing gaps between evidence and practice in areas such as stroke rehabilitation, mental health, and Indigenous health.
Researchers identified a candidate gene called DARC that may underlie differences in bone density between African-Americans and Caucasians. The study found that the DARC gene negatively regulates bone density in mice, and inhibiting its function could lead to therapies for osteoporosis.
Researchers have developed a software-based approach to detecting osteoporosis using routine dental x-rays, analyzing specific trabecular bone pattern features. This technique can predict osteoporotic conditions with the same accuracy as Bone Mass Density measurements.
Researchers at NIAID have discovered a protein that appears to regulate bone mass loss, which is a key factor in osteoporosis. The study, conducted on patients with X-linked Hyper IgM Syndrome, found that the loss of this protein accelerates bone loss.
Children with cancer are vulnerable to bone fragility, exacerbated by sedentary behaviors and treatment side effects. Early management through exercise and bisphosphonates can mitigate this risk.
A McMaster University researcher is warning men about osteoporosis, a bone-wasting disease that can severely affect them. One in eight men over 50 years old has osteoporosis, with higher risk groups identified.
A study of 4,124 older women found that repeat bone mineral density scans offered little predictive benefit for fractures. Initial BMD measurements remained highly predictive of fracture risk, suggesting that such tests are unnecessary for healthy older women.
A unique clinical study under way at FSU means to find out if daily prunes can help keep the doctor away by reversing bone loss in postmenopausal women. Researchers are expanding treatment options for osteoporosis, a debilitating disease affecting 10 million Americans.
Researchers have developed an automated method to identify osteoporosis sufferers in routine dental x-rays, which could help diagnose the disease earlier. The software measures jaw cortex widths, alerting dentists to potential cases, with a success rate comparable to specialist consultants.
A new study found that postmenopausal women who stop taking the osteoporosis drug alendronate after 5 years do not increase their risk of nonvertebral fractures, suggesting a lasting effect. The research also shows that BMD and bone marker levels remain at or above pretreatment levels 10 years after discontinuation.
A study by Geisinger Health System researchers found that EHR-based programs tripled the rate of osteoporosis screenings in at-risk women. High-risk women accounted for about half of those screened, highlighting the potential of EHRs to identify and prevent fractures related to osteoporosis.
A retrospective study of 33,000 women with osteoporosis found that Actonel significantly reduced the risk of hip fractures compared to alendronate. The results showed a 46% lower incidence of hip fractures at six months and a 43% reduction at 12 months.
A study published in the American Journal of Clinical Nutrition found that cola consumption is associated with lower bone mineral density in older women, regardless of age, menopausal status, or diet. This may be due to phosphoric acid's potential to promote calcium loss from bones.
A mathematic formula has been developed to predict a woman's risk of osteoporotic fracture, accurately identifying 75% of fractures two years after initial measurements were taken. The equation takes into account various risk factors beyond bone mineral density, allowing physicians to tailor treatment strategies to prevent fractures.
A study on liver transplant patients found that those with low bone density before transplant showed significant improvement afterwards. Bone loss immediately following transplant was common and several risk factors were identified, including PSC, younger age at transplant, and smoking.
A new study questions the use of estrens as estrogen-like molecules for treating osteoporosis. Estrens improved bone strength in mice, but also caused adverse effects on reproductive organs and human breast cancer cells. Further clinical trials are needed to determine their safety.
A new study recruiting up to 2,000 people from the remote Isles of Orkney aims to discover genes that predispose individuals to osteoporosis. The research will utilize a unique population isolated from the UK mainland, allowing for easier tracking and identification of genetic factors.
Researchers reveal that glucocorticoids, commonly used for inflammatory disorders, can cause osteoporosis by delaying osteoclast death and suppressing bone formation. Prolonged GC use affects bone health in mice with normal and disrupted GC receptors.
A study by family doctors found that women taking a monthly tablet of ibandronate and receiving telephone support showed a 47% greater persistence with their medication than those on weekly alendronate. This improved compliance is crucial in treating osteoporosis, which affects one in three women over 50 worldwide.
Researchers have identified a protein in mice that regulates bone formation, finding that augmented osteoblast activity leads to elevated bone mass. The discovery could lead to new treatments for osteoporosis by targeting the Shn3 and WWP1 proteins.
The number of hip fractures worldwide is projected to rise from 1.7 million in 1990 to 6.3 million in 2050, with estimated annual costs reaching $131.5 billion globally and $30 billion in the EU.
A new study by Stanford Medicine researchers found that the first osteoporosis medication, teriparatide, is not cost-effective compared to alendronate. The researchers suggest that teriparatide should be given only to high-risk patients who don't tolerate standard treatments.
Researchers found that orange and grapefruit juice can increase antioxidants in rats' systems, leading to enhanced bone density. The study suggests a potential link between citrus consumption and improved bone health.
Significant studies presented at the World Congress on Osteoporosis highlight the importance of calcium, vitamin D, and protein in building bones, as well as the impact of space travel, obesity, and smoking on bone health. The congress also emphasized the need for improved screening and treatment options for osteoporosis patients.
Seven young researchers from six countries have been awarded the IOF-Novartis Young Scholars' Award for outstanding contributions to osteoporosis research. The award aims to support and encourage careers in osteoporosis research, a field that has seen significant progress in understanding and treating this debilitating disease.
Studies in Sweden, China, and the US find strong links between smoking and osteoporosis, with smoking hastening bone erosion and increasing fracture risk. Second-hand smoke also significantly increases risk for osteoporosis and fractures in both men and women.
Dr Elise Feng-I Morgan, a researcher at Boston University, has been awarded the 2005 IOF-Servier Young Investigator Award for her innovative research on osteoporosis. This prestigious award aims to promote awareness and understanding of osteoporosis among young scientists.