Articles tagged with Pain
A recent study published in Archives of Internal Medicine found that 29% of chronic angina patients experience angina chest pain at least once a week. Despite treatment options, many patients report limited enjoyment of life due to the symptom.
A head-to-head study confirms Instanyl's superiority over oral transmucosal fentanyl citrate (OTFC) in managing breakthrough cancer pain. Instanyl demonstrated significant pain relief at all time points, with patients preferring its ease of administration and faster onset of action.
Researchers found that the endothelin receptor plays a role in vaso-occlusive pain in sickle cell disease, with males more sensitized to pain. Females have more of the ETB receptor, which may explain better pain control and reduced sensitivity.
A University at Buffalo researcher has found that people who live through traumatic experiences can bounce back and even grow stronger, thanks to certain qualities such as emotional expression, social support, and a positive outlook. These factors are crucial in predicting levels of distress and resilience among trauma survivors.
Dr. Paul Flecknell, a renowned expert in laboratory animal pain management, has been recognized with the 2009 Charles River Laboratories' Excellence in Refinement Award. His work focuses on developing methods of pain assessment and alleviation for various species.
A surgically implanted capsule-sized pump has been developed to provide continuous pain relief for big cats, reducing the need for daily injections. The pump was successfully used on two leopards at a Tennessee sanctuary, demonstrating its effectiveness in delivering pain medication quickly and efficiently.
Two novel biomarkers, sensitive cardiac troponin assays and copeptin, significantly improve early detection of acute myocardial infarction. These markers enable doctors to diagnose AMI in the vast majority of patients presenting with chest pain, reducing complications and costs.
Researchers at Duke University Medical Center found that mice deficient in Type IX collagen develop osteoarthritis and degenerative disc disease, leading to impaired physical abilities and increased pain sensitivity. The study provides valuable insights into the effects of collagen deficiency on musculoskeletal disorders.
A recent report from the University of Western Ontario warns that codeine use after tonsillectomy can be deadly for some children due to ultra-rapid metabolism genotypes. The study highlights the need for cautious prescribing and monitoring of pain relief medication in these cases.
A recent study by the Medical College of Wisconsin found that ibuprofen is as effective as acetaminophen with codeine in treating pain in children with arm fractures. The study showed that children treated with ibuprofen reported better functional outcomes and higher satisfaction rates than those receiving acetaminophen with codeine.
A study published in Proceedings of the National Academy of Sciences has identified a genetic link between physical pain sensitivity and social rejection. Researchers found that individuals with a rare form of the OPRM1 gene are more sensitive to rejection and experience increased brain activity in response to rejection.
A study published in Archives of Otolaryngology–Head & Neck Surgery found that post-treatment pain in head and neck cancer patients is associated with a lower five-year survival rate and increased risk of recurrence. Pain was also linked to age, general health conditions, and treatment modality.
Uterine fibroid embolization is a minimally invasive treatment that cuts off blood flow to painful fibroids, killing tumors and subsiding symptoms. This procedure can significantly decrease the hysterectomy rate in the United States, benefiting over 300,000 women annually.
Patients with primary sclerosing cholangitis (PSC) have significantly larger fasting and postprandial gallbladder volumes compared to healthy controls. However, there is no correlation between gallbladder size or emptying and the occurrence of abdominal pain in PSC patients.
Researchers found that professionals influenced executions by emphasizing propriety and efficiency, leading to modern, rational execution events. The scientific gaze has been turned onto itself, prompting innovations to reduce pain and suffering.
In a breakthrough study, researchers identified itch-specific neurons in mice that can be targeted to alleviate chronic itching. The discovery suggests that itch and pain signals are transmitted through different pathways in the spinal cord, offering new hope for treatments.
A new study found that relief of pain and improvement in function were similar in patients treated with vertebroplasty and simulated vertebroplasty without cement injections. The study raises questions about the procedure's long-term efficacy, suggesting that other factors may contribute to its benefits.
Adding anesthetic lidocaine to radiocolloid injection improves patient comfort without compromising SLN identification, reducing pain and discomfort for patients with early breast cancer. The study concludes that this practice should be introduced as standard.
A study led by Abhinav Chandra found that emergency physicians' estimates of risk for chest pain patients correlate with actual outcomes. The researchers suggest trusting the physician's gut instinct and counseling against discharge when strongly advised, even without compelling data.
A new project called PROMIS aims to establish a common scientific vocabulary for measuring pain, fatigue, depression, anxiety, and physical/social functioning. This will help researchers compare results and evaluate treatment benefits more effectively, enabling better care for patients with chronic diseases.
A new treatment method, Vesselplasty, has been shown to reduce pain and improve mobility in patients with vertebral compression fractures. The study, which included 29 patients, found significant improvements in pain scores and mobility, with no clinical complications reported.
Researchers found that counting money reduced social distress and physical pain compared to counting paper, while thinking about finances increased these negative reactions. The study suggests that the mere idea of money has considerable psychological power.
Researchers have found that a simple bar and strengthening exercise may provide a practical and effective means of treating tennis elbow. The study, which randomized 21 patients with tennis elbow into two groups, showed that the eccentric training group had vastly better results on all scales, especially related to strength.
A study found that cardiac CT workups are more cost-effective than traditional care for low-risk chest pain patients, reducing hospital stays by up to 20 hours and lowering charges by 44%. This innovative approach has the potential to significantly reduce costs in emergency departments.
Researchers at Tufts University developed a tissue regeneration application that maintains complete root coverage after three years with minimal pain and recovery time. This innovative approach uses platelet concentrate gel instead of traditional grafting methods, resulting in improved esthetics and patient satisfaction.
Researchers found that perceiving others in pain activates a part of the brain associated with empathy and emotion more if the observer and the observed are the same race. This study confirms an in-group bias in empathic feelings, which has significant implications for understanding real-life social behaviors and interactions.
A new minimally invasive procedure has been shown to provide immediate symptom relief for patients with rotator cuff tendonitis. The treatment uses ultrasound-guided percutaneous therapy to break up calcium deposits and restore mobility. Results showed significant improvement in pain and mobility, even at long-term follow-up.
A study found that MDCT with prospective ECG triggering reduces chest radiation dose by 71% compared to retrospective gating, delivering a lower dose of 9mSv. Image quality was also slightly better with prospective triggering.
A study published in Academic Emergency Medicine found that patients with heart attacks and chest pain are three to five times more likely to experience serious complications when treated in a crowded ER. The authors attribute the increased risk to poorer care coordination, delays in testing, and overburdened doctors and nurses.
Researchers present latest advances in Natural Orifice Translumenal Endoscopic Surgery (NOTES), eliminating incisions and reducing recovery time. Studies show promising results for procedures like cholecystectomy, appendectomy, and gastrectomy with fewer complications.
A systematic review and meta-analysis found that Tai Chi decreases pain in people with arthritis, improving physical function and quality of life. Additionally, it is an inexpensive, convenient, and enjoyable form of exercise that conveys psychological and social benefits.
A study suggests air pollution may contribute to non-specific abdominal pain in young women, while another study shows that moderate alcohol intake can reduce the risk of gallstones. The findings highlight the importance of environmental factors and lifestyle choices on GI health.
Research suggests music can reduce pain and encourage better oral feeding in premature babies, leading to calmer infants and parents. The studies found preliminary evidence of therapeutic benefits, including improved physiological measures and behavioral states.
Researchers developed a strategy to improve both depression and pain management by closely monitoring antidepressant therapy and providing pain self-management training. The study found that this approach led to substantial improvements in both conditions, with benefits lasting six months after treatment was completed.
A combined pharmacological and behavioral intervention improved depression and pain in patients with musculoskeletal pain and co-existing depression. The intervention significantly reduced symptoms of both conditions at 12 months.
Scientists have directly elucidated the emergence of mechanosensitivity in mice, finding it arises during specific developmental phases with the growth of neuronal pathways. The study suggests a genetic program drives this process, which is distinct from pain sensitivity development.
A new survey reveals that post-menopausal women are reluctant to discuss vaginal dryness and pain due to embarrassment, affecting up to 47% who prefer discussing symptoms with a female physician. Despite this, 67% of those treated experience improvements in quality of life and sexual activity.
A new study by the University of Pennsylvania School of Medicine found that women with chest pain are less likely to receive recommended treatments, such as aspirin and nitroglycerin, from paramedics. This disparity in care may be due to differences in symptom interpretation or patient communication, emphasizing the importance of direc...
A long-term study confirms the efficacy of CT scans in ruling out serious cardiovascular disease in patients with chest pain, with no cases of heart attacks or cardiac stents needed within a year after negative scans. The test streamlines the process, providing faster and less expensive evaluation options.
The American College of Radiology has reaffirmed its support for clinical patient management by vascular and interventional radiologists. These specialists provide minimally invasive treatment options with less risk, pain, and recovery time compared to open surgery. With this extension, interventional radiologists are formalizing their...
A new study published in Archives of Internal Medicine finds that women with chest pain but no coronary artery disease are at an elevated risk for cardiovascular events such as heart attack or stroke. The study suggests that these patients require a different treatment regimen and highlights the need to reevaluate their risk assessment.
A recent study found that infants who receive the pneumococcal conjugate vaccine (PCV) after the DPTaP-Hib vaccine experience less pain than those who receive it first. The authors suggest varying the order of vaccine administration to reduce pain.
Researchers developed an animal model for sciatica, a painful nerve condition characterized by numbness, pain, and leg difficulties. The study found that immune system activation contributes to symptoms, with elevated IL-17 levels linked to physical symptoms.
A study at the University of Washington found that cardiac CT is a cost-effective approach to diagnose low-risk chest pain patients, reducing costs by 44% and shortening hospital stays by up to 20 hours. The new technique uses lower-dose cardiac CT options, allowing for faster evaluation and discharge in under six hours.
Patients with vertebral compression fractures experience prolonged intense pain, with over two-thirds reporting severe pain one year after injury. Current treatment and advice are deemed insufficient, requiring revised approaches to improve patient outcomes.
Researchers found that demand for pain relief is almost completely dependent on recent past pain experience and available cash. The study's results suggest that the value of pain relief is flexible and cannot be predicted by individual behavior, with significant economic implications.
Researchers at Duke University Medical Center used new imaging technology to discover nearly 200,000 people in the US suffer 'silent' heart attacks each year. These unrecognized myocardial infarctions are linked to a surprisingly high risk of untimely death and may be more common than previously believed.
A study by Queen's University researchers found that pelvic pain symptoms occur as frequently in adolescent boys as in adult men. Chronic pelvic pain syndrome has a significant negative impact on quality of life, including depression and social relationships.
A study of 1970 patients found a strong association between gastroesophageal reflux disease and linked angina. Patients with GERD had a higher prevalence of linked angina than those without GERD symptoms, suggesting that GERD may be misclassified as non-GERD heartburn.
A study published in the Journal of Clinical Sleep Medicine suggests that sleep problems lead to increased ratings of pain and fatigue in cancer patients. The research indicates that addressing sleep issues may improve pain management for this patient population.
Researchers have made a groundbreaking discovery in the treatment of bone injuries, using teriparatide to jumpstart the body's natural healing process. The study shows significant healing and pain control in patients with unhealed bone fractures, offering new hope for those with no effective treatment options.
Researchers found a specialized nerve fiber in skin that transmits stroking signals directly to the brain, potentially explaining why touching can relieve pain. The study used microneurography to analyze nerve signals and found that increased frequency of these signals led to increased pleasantness.
A new study led by USC neuroscientists found that admiring others' virtues or feeling compassion for physical or social pain takes time to fully respond to, unlike faster reactions to fear and pain. The research suggests a need to allow for reflective moments in digital media culture.
A study by University of Illinois professor Robert Motl found that caffeine reduces muscle pain during high-intensity exercise in both caffeine-naïve individuals and habitual users. The study suggests that pain during exercise may not show tolerance effects to caffeine.
The study found that delivering a potent form of autologous adult stem cells into the heart muscle of patients with severe angina improved exercise tolerance and reduced episodes of chest pain. Six months after the procedure, treated patients were able to walk longer on a treadmill than those in the placebo group.
A recent study published in Animal Behaviour has shown that crabs suffer from pain and retain a memory of it. The research found that shocked crabs were more likely to move towards new shells, indicating they recall the experience.
A study by Oregon Health & Science University found that patients requesting physician-assisted death cite concerns about future suffering as a leading motivator. The study surveyed 56 patients and ranked factors influencing their requests, highlighting the importance of symptom control and patient sense of control.
Osteoplasty provides immediate and substantial pain relief for metastatic bone disease patients, often referred to as the 'Lazarus effect'. The procedure involves injecting bone cement into weakened bones, improving quality of life and allowing patients to resume daily activities.
A new device, CPSM, measures continuous real-time pain scores, providing detailed information on patients' pain perception and improving pain management. The study used thirty-two healthy volunteers to test the CPSM's reliability.
A new study found that patients who underwent rotator cuff repair surgery experienced continued pain relief and improved shoulder function, even after a tear recurrence. The study of 15 patients eight years after surgery showed that those with recurrent tears were better off in terms of pain, function, and strength than before.