Articles tagged with Pain
A long-term study confirms the efficacy of CT scans in ruling out serious cardiovascular disease in patients with chest pain, with no cases of heart attacks or cardiac stents needed within a year after negative scans. The test streamlines the process, providing faster and less expensive evaluation options.
The American College of Radiology has reaffirmed its support for clinical patient management by vascular and interventional radiologists. These specialists provide minimally invasive treatment options with less risk, pain, and recovery time compared to open surgery. With this extension, interventional radiologists are formalizing their...
A new study published in Archives of Internal Medicine finds that women with chest pain but no coronary artery disease are at an elevated risk for cardiovascular events such as heart attack or stroke. The study suggests that these patients require a different treatment regimen and highlights the need to reevaluate their risk assessment.
A recent study found that infants who receive the pneumococcal conjugate vaccine (PCV) after the DPTaP-Hib vaccine experience less pain than those who receive it first. The authors suggest varying the order of vaccine administration to reduce pain.
Researchers developed an animal model for sciatica, a painful nerve condition characterized by numbness, pain, and leg difficulties. The study found that immune system activation contributes to symptoms, with elevated IL-17 levels linked to physical symptoms.
A study at the University of Washington found that cardiac CT is a cost-effective approach to diagnose low-risk chest pain patients, reducing costs by 44% and shortening hospital stays by up to 20 hours. The new technique uses lower-dose cardiac CT options, allowing for faster evaluation and discharge in under six hours.
Patients with vertebral compression fractures experience prolonged intense pain, with over two-thirds reporting severe pain one year after injury. Current treatment and advice are deemed insufficient, requiring revised approaches to improve patient outcomes.
Researchers found that demand for pain relief is almost completely dependent on recent past pain experience and available cash. The study's results suggest that the value of pain relief is flexible and cannot be predicted by individual behavior, with significant economic implications.
Researchers at Duke University Medical Center used new imaging technology to discover nearly 200,000 people in the US suffer 'silent' heart attacks each year. These unrecognized myocardial infarctions are linked to a surprisingly high risk of untimely death and may be more common than previously believed.
A study of 1970 patients found a strong association between gastroesophageal reflux disease and linked angina. Patients with GERD had a higher prevalence of linked angina than those without GERD symptoms, suggesting that GERD may be misclassified as non-GERD heartburn.
A study by Queen's University researchers found that pelvic pain symptoms occur as frequently in adolescent boys as in adult men. Chronic pelvic pain syndrome has a significant negative impact on quality of life, including depression and social relationships.
A study published in the Journal of Clinical Sleep Medicine suggests that sleep problems lead to increased ratings of pain and fatigue in cancer patients. The research indicates that addressing sleep issues may improve pain management for this patient population.
Researchers have made a groundbreaking discovery in the treatment of bone injuries, using teriparatide to jumpstart the body's natural healing process. The study shows significant healing and pain control in patients with unhealed bone fractures, offering new hope for those with no effective treatment options.
Researchers found a specialized nerve fiber in skin that transmits stroking signals directly to the brain, potentially explaining why touching can relieve pain. The study used microneurography to analyze nerve signals and found that increased frequency of these signals led to increased pleasantness.
A new study led by USC neuroscientists found that admiring others' virtues or feeling compassion for physical or social pain takes time to fully respond to, unlike faster reactions to fear and pain. The research suggests a need to allow for reflective moments in digital media culture.
A study by University of Illinois professor Robert Motl found that caffeine reduces muscle pain during high-intensity exercise in both caffeine-naïve individuals and habitual users. The study suggests that pain during exercise may not show tolerance effects to caffeine.
The study found that delivering a potent form of autologous adult stem cells into the heart muscle of patients with severe angina improved exercise tolerance and reduced episodes of chest pain. Six months after the procedure, treated patients were able to walk longer on a treadmill than those in the placebo group.
A recent study published in Animal Behaviour has shown that crabs suffer from pain and retain a memory of it. The research found that shocked crabs were more likely to move towards new shells, indicating they recall the experience.
A study by Oregon Health & Science University found that patients requesting physician-assisted death cite concerns about future suffering as a leading motivator. The study surveyed 56 patients and ranked factors influencing their requests, highlighting the importance of symptom control and patient sense of control.
Osteoplasty provides immediate and substantial pain relief for metastatic bone disease patients, often referred to as the 'Lazarus effect'. The procedure involves injecting bone cement into weakened bones, improving quality of life and allowing patients to resume daily activities.
A new device, CPSM, measures continuous real-time pain scores, providing detailed information on patients' pain perception and improving pain management. The study used thirty-two healthy volunteers to test the CPSM's reliability.
A new study found that patients who underwent rotator cuff repair surgery experienced continued pain relief and improved shoulder function, even after a tear recurrence. The study of 15 patients eight years after surgery showed that those with recurrent tears were better off in terms of pain, function, and strength than before.
Researchers found that artificial disc replacement is as effective as, or even better than, spinal fusion surgery in treating damaged discs in the neck. Patients who received an artificial disc lost less motion and recovered faster than those who had a disc removed and the bones of the spine fused.
Researchers found that spasm of the esophageal smooth muscle may trigger myocardial ischemia, leading to chest pain. The combination of these tests is significant for differential diagnosis, especially with foregut symptoms, and is cost-effective for patients from developing countries.
A recent study published in The Lancet found that a short period of immobilization with a below-knee cast results in faster recovery from severe ankle sprains compared to other treatments. The authors recommend using a 10-day below-knee cast or an Aircast brace for management.
A meta-analysis of randomized controlled trials found no significant differences between immediate imaging and usual clinical care for patients with acute or sub-acute low-back pain. The authors recommend refraining from routine imaging unless serious underlying conditions are suspected, to reduce unnecessary tests and improve patient ...
A study published in Pediatric Blood & Cancer found significant variation in end-of-life care practices among children's hospitals, with substantial differences in opioid prescriptions and pain management. The findings highlight the need for individualized interventions to improve pediatric end-of-life care.
A new technique combining CT with fiber-coated surgical microcoils successfully locates and removes small lung nodules using video-assisted thoracoscopic surgery. The procedure results in less pain and faster recovery times compared to traditional thoracotomy, allowing patients to return to work within two to three days.
A randomized, double-blind, placebo-controlled study found that long-term administration of chondroitin sulfate can prevent joint structure degradation in patients with knee OA. The study also showed significant reductions in joint space loss, pain, and adverse events in the treatment group compared to the placebo group.
Individuals with chronic back and neck pain are less likely to receive exercise prescriptions, with physical therapists prescribing it most frequently. Exercise is a moderately effective therapy for this highly disabling illness, but its underutilization may hinder treatment outcomes.
Researchers found that patients who received telephone support had 35% fewer complaints of pain and discomfort compared to those in the control group. They also reported fewer anxiety, depression, and mobility problems.
A clinical trial from Northwestern University's Feinberg School of Medicine found that supervised exercise can improve walking endurance for people with peripheral arterial disease. Participants were able to walk an average of 69 feet further after six months of supervised treadmill walking, and reported a better quality of life.
A new study found that stronger quadriceps muscles protect against cartilage loss in the lateral compartment of the patellofemoral joint, a site of frequent cartilage loss and pain in patients with knee OA. Greater quadriceps strength also showed to have less knee pain and better physical function than those with weaker muscles.
Patients with PAD who participated in supervised treadmill exercise showed significant improvements in walking endurance and quality of life. The exercise program also improved walking performance for those without classic symptoms of pain in the leg muscles.
Researchers at Massachusetts General Hospital and University of Pennsylvania found that COX2 in mouse nerve cells plays a crucial role in pain caused by physical insult, while PDE5 inhibition may prevent hypertrophy in the mouse heart. These findings have implications for treating conditions such as postoperative and arthritic inflamma...
COX2 in brain and spinal cord nerve cells plays a crucial role in pain caused by inflammation, particularly mechanical inflammatory pain. Mice lacking COX2 in nerve cells have impaired hypersensitivity to pain caused by physical insult, suggesting COX2 is central to this type of pain.
A study found that antioxidant supplementation reduced painful days and analgesic use in patients with chronic pancreatitis. The benefits were seen as early as three months and suggest a state of heightened free radical-mediated injury in the disease.
A new screening test using barium meal follow through with pneumocolon has been proposed for chronic abdominal pain of luminal origin. The test can detect both small and large bowel lesions, reducing the need for separate colonoscopy procedures.
Adult cystic fibrosis patients can accurately predict their mortality based on their own reported quality of life. Patient-reported pain was found to be a critical factor in determining survival rates, highlighting the importance of using patient-reported measures in clinical trials.
Researchers identified clinical characteristics of Fitz-Hugh-Curtis syndrome in 22 female patients, noting pain in the upper right abdomen and lower abdomen. Antibiotic treatment cured 20 patients, highlighting the importance of abdominal CT scans for diagnosis.
Research at UCL found premature infants who required intensive care or surgery have reduced sensitivity to temperature and pain later in life. This study, published in the journal Pain, suggests that early medical interventions may alter how children respond to painful stimuli.
A commonly-prescribed drug for men suffering from pelvic pain failed to significantly reduce symptoms in a 12-week international study. Researchers can now focus on more promising therapies.
A recent clinical trial sponsored by NIH found that alfuzosin, a commonly prescribed drug for chronic prostatitis, did not significantly reduce symptoms in newly diagnosed men. The study showed no significant differences between the treatment and placebo groups in terms of symptom improvement.
A new study published in the Spine journal found that manual physical therapy and exercise significantly improves neck pain, reducing mechanical neck pain and disability. Physical therapists can provide a conservative solution to musculoskeletal pain without expensive surgery or medication side effects.
A study by Kurt Gray and Daniel Wegner found that participants who believed they were getting an electrical shock from another person on purpose rated the shock as more painful. In contrast, those given shocks unintentionally habituated to the pain over time.
New research shows regular exercise can significantly improve peripheral artery disease (PAD) symptoms by increasing collateral blood flow and enhancing vascular efficiency. Exercise training can delay pain onset and increase mobility in people with PAD.
A recent study published in Redox Report reveals that Pycnogenol significantly lowers plasma levels of C-reactive protein (CRP) in osteoarthritis patients. This finding suggests that Pycnogenol's anti-inflammatory potency may be potent enough to arrest the spread of inflammation from osteoarthritic joints to the whole organism.
A new ultrasound-guided technique combined with steroid injection has been shown to be 95% effective in relieving plantar fasciitis symptoms within three weeks. This treatment is a viable option for patients who have tried conservative treatments and are experiencing persistent pain.
A study published in the World Journal of Gastroenterology found that almost 30% of patients with CSX no longer exhibited typical chest pain after gastroenterological workup. Treatment with proton pump inhibitors significantly improved symptoms, suggesting a strong link between acid-related disorders and CSX.
The study found that CAPHOSOL results in a low incidence of oral mucositis, moderate to severe pain, and dysphagia. Patient satisfaction rates were high, with 79% describing themselves as satisfied or very satisfied with the treatment.
A Japanese research team discovered that the wasabi receptor can sense and respond to ammonia, a base known to cause pain. The study, published in Journal of Clinical Investigation, reveals the molecular entity responsible for this phenomenon, providing insight into the mechanisms behind sushi-induced discomfort.
New research reveals that alkaline pH activates TRPA1 protein in human cell lines and mouse nerve cells, leading to pain sensation. The study suggests that activation of this protein might be the mechanism underlying some human alkaline pH-related pain sensations.
A study found that doctors are unsure about the legality of deactivating an implantable cardioverter-defibrillator (ICD) in terminally-ill patients, leading to unnecessary pain. The researchers recommend educating physicians on managing end-of-life care for ICD patients.
Research using brain scans at the University of Chicago found that aggressive youth activated neural circuits underpinning pain processing when watching pain inflicted on others. The study suggests some aggressive youths' natural empathetic impulse may be disrupted, increasing aggression.
A GSU study confirms that administering morphine prior to a painful procedure in infancy blocks long-term negative consequences of pain in adult rodents. Infant rodents who did not receive preemptive pain medication were less sensitive to morphine in adulthood, highlighting the need for pain relief in newborns.
A national survey found that patients generally satisfied with their care but identified areas for improvement in pain management and discharge instructions. Hospitals with higher nurse-to-patient ratios and more satisfied patients tend to provide better quality care.
A Université de Montréal study discovered that facial expressions of intense pain are a genuine reflection of the brain's response to painful stimulation. The research, led by Miriam Kunz, found that individuals with more intense facial reactions had lower pain thresholds.
Adults with arthritis who received exercise interventions with educational components experienced significant improvements in physical functioning and pain reduction. These patients also reported increased muscle strength and better mental health, compared to those without such interventions.
A study published in The Lancet Neurology found that patients in a minimally conscious state may experience pain perception similar to healthy individuals. This suggests that these patients could benefit from painkilling treatment, which is currently challenging due to limited awareness of their condition.
A randomized clinical trial found that changing dosing and administration of an anthrax vaccine to intramuscular injection resulted in fewer adverse events while maintaining comparable effectiveness. The study also discovered that a reduced 3-dose schedule was noninferior to the licensed regimen.