Articles tagged with Pain
A recent study found that nearly one in five patients experiences chest pain one year after having a heart attack. Patients who experienced chest pain were more likely to be younger, non-white males with prior chest pain, and had poorer health outcomes.
Currently used pain assessment tools may not accurately reflect the pain experience in infants. A study published in PLOS Medicine found that changes in brain activity correlated with clinical pain scores, but were more strongly linked to behavioral components such as facial expression than physiological components like heart rate. The...
Research shows that patients need to re-learn the sit-to-stand position technique after TKA, relying on a larger hip extensor movement. Physical therapists can help by teaching correct techniques, potentially preventing future knee osteoarthritis.
Researchers at the University of Montreal have established the cause of hereditary sensory and autonomic neuropathy type II, a severe disorder characterized by loss of sensation in limbs. The WNK1/HSN2 isoform has been identified as the underlying gene mutation, allowing for the development of animal models and potential pain treatments.
A study of ongoing randomized clinical trials in diabetes reveals that only 20% have primary outcomes important to patients, such as illness, pain, or death. The researchers emphasize the need for a standard set of patient-important outcomes in diabetes trials to improve their informativeness.
A randomized clinical trial found that oral prednisolone is clinically equivalent to naproxen in reducing pain and inflammation in patients with gout. The study suggests that prednisolone could be a safer alternative for treating gout, with potential economic benefits due to reduced healthcare costs.
Lubiprostone has been shown to significantly improve all IBS-C symptoms in women, including abdominal pain, bloating, and constipation severity. The drug is also effective in treating IBS-C for up to one year, with improved stool consistency and reduced nausea and diarrhea.
CAPHOSOL, an advanced electrolyte solution, has been shown to relieve oral mucositis and improve quality of life for cancer patients. The study found that 95% of patients reported favorable OM scores and high levels of patient and practitioner satisfaction with CAPHOSOL.
Researchers at Johns Hopkins Medicine have identified a gene, Pirt, that regulates a heat-activated molecular sensor, leading to variable pain sensitivity. The study found that mice lacking Pirt responded slower to heat and were less sensitive to capsaicin, suggesting Pirt's specific role in pain perception.
Researchers have discovered a timing mechanism in the brain of fruit fly larvae that controls their avoidance of food and could lead to new pain relief methods. This mechanism has counterparts in mammalian models involved in psychological processes such as food response, anxiety suppression, and pain perception.
Researchers found that using a cane significantly reduced the peak knee adduction moment, alleviating destructive load on affected knees. The study suggests that canes may be an effective short-term solution for knee OA patients.
A study published in Arthritis Care & Research reveals that obese patients undergoing revision total hip arthroplasty (THA) are at a higher risk of complications, including surgical site infections and dislocations. The research found a strong correlation between obesity and adverse events after revision THA.
A new study reveals that women are more likely to experience atypical symptoms such as nausea and jaw pain during a heart attack, leading to delayed treatment. Women were also less likely to receive life-saving treatments like beta blockers, statins, and angioplasty compared to men.
A study published in The Lancet found that nearly 30% of men and women reported feeling some level of pain at sampled times. People with lower incomes or less education spent more time in pain and had higher average pain ratings. Pain also imposes significant costs on the healthcare system, economy, and lost productivity.
A Princeton University survey found that 28% of Americans experience pain at any given moment, with those with less education and lower income spending more time in pain. The study also showed that pain can be a barrier to socializing, working, and overall well-being.
Researchers at NIMH found that brain activity responds to social hierarchy, influencing motivation and health. The ventral striatum activates equally for monetary rewards and changes in rank.
Research shows that preterm babies can recover from pain faster when given kangaroo mother care, reducing facial expressions of pain and recovery time. This approach could also have benefits for mothers whose parental role diminishes while their baby is in intensive care.
A study published in the April 2008 edition of the journal Phytotherapy Research found that Pycnogenol, an antioxidant plant extract from pine bark, significantly reduced osteoarthritis symptoms by 56% and joint pain by 55%. The treatment also improved physical function by 56% and increased patient mobility almost three-fold.
A recent study published in Arthritis Care and Research journal found that regular exercise, specifically the Arthritis Foundation Exercise Program, significantly improves and manages arthritis pain. Participants reported a decrease in pain and fatigue, an increase in upper and lower extremity function, and increased strength after par...
A recent survey of over 13,000 shoppers reveals that tightwads are more prevalent than spendthrifts due to the emotional pain associated with spending. Tightwads tend to save because forking out money is too painful an experience.
A review of published literature on women's expectations and experience of pain and pain relief in labour reveals a gap between expectations and reality. Most women underestimate the intensity of pain they will experience and may not be prepared for the possibility that they might need pain relief.
A provocative study by Dan Ariely found that a 10-cent pill is less effective at killing pain than a $2.50 pill, even when they are identical placebos. The study suggests that patients' subjective ratings of pain are influenced by the perceived quality and cost of medications.
A study by Ohio State University found no improvement in immune status, wound healing, or pain control among participants exposed to aromatherapy oils. However, lemon oil showed a positive effect on moods, while lavender oil had no impact.
Klaus Keller's research suggests that the North Atlantic meridional overturning circulation (MOC) may respond to human-made greenhouse gas emissions in a threshold response. Improved MOC observation systems could provide an early warning of an approaching collapse, enabling more effective climate policies.
Patients with larger social networks report less pain and anxiety before surgery, which can positively impact their recovery. Clinicians should be aware of the link between social networks and patient recovery after major operations.
A new study published in Arthritis Care & Research found that taking two NSAIDs was associated with lower scores on a health-related quality of life assessment. Dual use was also linked to worse physical functioning and symptoms, highlighting the need for better pain management and patient communication.
Women with irritable bowel syndrome (IBS) who experienced sexual and/or physical abuse may have a heightened brain response to pain, making them more sensitive to abdominal discomfort. Researchers found that patients with IBS background of abuse were less effective in turning off a pain modulation mechanism in the brain.
The American College of Physicians has issued new guidelines to improve palliative care at the end of life, focusing on pain, shortness of breath, and depression. The guidelines recommend regular assessment and use of proven therapies to manage these symptoms, with a focus on improving quality of care for patients with serious illnesses.
Recent studies in Annals of Internal Medicine reveal significant advancements in palliative care and insights into sickle cell disease's prevalence. Researchers also discovered a new strain of antibiotic-resistant Staphylococcal Infections primarily affecting men who have sex with men, emphasizing the need for targeted prevention measu...
Research at the University of Delaware found women with osteoarthritis in their knees have significantly reduced mobility and function compared to men. Women may need to become more educated about knee-replacement surgery risks and benefits to preserve their mobility and quality of life.
The study evaluated the Arthritis Foundation Exercise Program's effects on managing arthritis through exercise. The results showed significant improvements in pain, fatigue, and physical function, with continued benefits when participants maintained program participation at home.
A 20-minute evening back massage was found to decrease pain intensity and unpleasantness, as well as anxiety, in patients undergoing major surgery. The study suggests that massage may act through multiple mechanisms, including relieving anxiety and generating mood-boosting endorphins.
A new study by University of Iowa researcher Vera Loening-Baucke found that acute and chronic constipation accounted for nearly half of all cases of acute abdominal pain in children. The study recommends that physicians perform a simple rectal examination to diagnose constipation as a cause of abdominal pain.
A study found that many cancer patients with metastatic disease incorrectly believe opioids are only for dying patients. Morphine can improve pain management and quality of life for living patients. Experts stress the importance of professional confidence in opioid use to change these beliefs.
Researchers found that stress hormone noradrenaline suppresses pain inputs from the brainstem, reducing neurotransmitter launch and triggering nerve impulses. The study provides important mechanistic clues to understanding stress-induced analgesia.
A review of six knee osteoarthritis treatment guidelines found significant differences in recommended treatments, with a focus on acetaminophen, NSAIDs, and exercise. The study highlights the need for more detailed educational interventions to improve guideline applicability.
A double-blind study published in Nutrition Research reveals Pycnogenol improves physical function by 52 percent in patients suffering from OA. The antioxidant plant extract also controls inflammation and complements existing strategies for treating osteoarthritis.
A study led by Ronald Epstein found that doctors voiced empathy in only 15% of office visits, despite repeated prompting from patients. Patients reported high satisfaction when doctors empathized with them, especially in challenging situations.
Researchers found that patients over 60 years old, experiencing morning stiffness and groin pain, are at higher risk of undergoing total hip replacement. The study also revealed that obesity may decrease the risk of THR after three years.
A study of over 3,000 adults found that meniscal damage is often present in knees with osteoarthritis, but not directly responsible for pain. The researchers suggest that treating OA as a whole-joint disorder may help clarify the relationship between meniscal damage and knee symptoms.
A new minimally invasive procedure using ultrasound-guided percutaneous therapy significantly reduces pain and restores mobility in patients with calcific tendonitis of the rotator cuff. The procedure, which takes about an hour to perform, has been shown to provide long-lasting relief from symptoms.
A Mayo Clinic study shows cryoablation can provide durable pain relief for patients with bone metastases. Eighty percent of patients experienced significant pain reduction after the treatment, which also improved their quality of life.
A study published in CANCER found that non-white women with metastatic breast cancer experience poorer pain control, with a higher risk of severe pain. The researchers also found that inactive performance status and previous radiation treatment were associated with greater pain.
A rare case of antegrade bowel intussusception after pancreatic duct reconstruction was reported, leading to a diagnosis of severe variant of Roux-en-Y stasis syndrome. The patient had previous episodes of abdominal pain and vomiting suggesting altered intestinal motility.
The study found that children who received continuous peripheral nerve blockade (CPNB) for pain management after orthopaedic surgery had better pain control and a shorter hospital stay. The catheter system offers continuous relief for up to 100 hours, potentially cheaper than alternative treatments and long hospital stays.
BioDelivery Sciences International has submitted its New Drug Application for BEMA Fentanyl, a treatment for breakthrough cancer pain, to the FDA. The application is based on positive results from clinical trials, including a Phase III efficacy trial that demonstrated significant pain reduction and low discontinuation rates.
A new study by Mayo Clinic researchers found that massage therapy decreases pain levels for patients after heart surgery. In a pilot study of 58 patients, those who received massage had mean pain scores less than 1 on a scale of 1 to 10, compared to an average rating of 3 among the control group.
Researchers found that injecting a dextrose solution under ultrasound guidance can reduce pain in patients with chronic Achilles tendinosis. After treatment, 20 of 30 patients remained asymptomatic, while nine had only mild symptoms.
Research suggests that early intervention with angioplasty improves survival and reduces the risk of heart attack in women. Women are at higher risk of bleeding complications, but this does not justify withholding life-saving procedures.
Researchers found acid reflux was a significant factor in patients experiencing serious chest pain and persistent cough. A cost-effective diagnostic tool may help determine which patients benefit from anti-reflux surgery.
A small study found that eptifibatide, an intravenous blood thinner, appears to be well-tolerated in sickle cell patients and shows potential benefits in reducing inflammation. The results suggest that the drug may have anti-inflammatory effects without causing harm to these patients.
Scientists have successfully selectively blocked pain-sensing neurons in rats without interfering with other types of neurons, offering a new targeted approach to pain management. The method uses QX-314 and capsaicin to target only pain-sensing neurons, preventing them from sending signals to the brain.
Researchers found that doctors can learn to control their brain's automatic pain response, allowing them to better treat patients. The study showed that doctors activate the neural circuit related to emotion regulation and cognitive control when watching videos of people in pain.
A recent study suggests that an abnormal amount of inflammatory cells in the duodenum may be responsible for nonulcer dyspepsia, a condition characterized by chronic or recurrent abdominal pain. The researchers propose targeted anti-inflammatory medicine as a potential treatment option.
Researchers found that the widely-used numeric rating scale (NRS) fails to identify about a third of patients with pain serious enough to impair day-to-day functioning. The study highlights the limitations of universal pain screening and suggests that other methods may be more effective in addressing this common problem in primary care.
A study found that a specific tonsil removal technique associated with reduced postoperative heavy bleeding and pain. The intracapsular technique, which removes at least 90% of tonsil tissue while sparing the capsule, resulted in fewer complications compared to traditional tonsil removal surgery.
A recent study published in the Journal of the National Cancer Institute found that hypnosis prior to breast cancer surgery reduced the amount of anesthesia used during the operation, as well as levels of pain and other side effects reported afterwards. This resulted in shorter hospital stays, fewer readmissions, and lower surgical costs.
Patients with respiratory problems face a higher risk of death during longer ambulance journeys, which can range from 0 to 58 kilometres. The study found that the further the patient has to travel, the more likely they are to die, with a 13% increase in mortality for those with breathing problems over 20km distances.
Researchers found that whiplash trauma increases the risk of developing temporomandibular joint (TMJ) symptoms, which can be painful and affect daily life. In a study of 60 patients, 34% developed TMJ pain within a year after the accident, compared to 7% in uninjured controls.
A new study is expected to reveal the true cost of persistent pain in Australia, with an estimated 1 in 5 Australians suffering from relentless pain. The research aims to identify priority actions to ease suffering and save healthcare dollars.