Articles tagged with Pain
Researchers found that pain signals from arthritic joints worsen and expand the disease by transferring inflammation to the spinal cord. New treatments aim to interrupt 'crosstalk' between joints and the spinal cord to treat osteoarthritis.
University of Iowa researchers are investigating the roles of the pituitary gland and sympathetic nervous system in interstitial cystitis inflammation. The study aims to identify potential causes of the painful bladder condition, which affects over 1 million Americans.
The study found that CAPHOSOL treatment significantly limits the occurrence and severity of oral mucositis, with high levels of medication compliance and patient/physician satisfaction reported. Compliance was very high, with nearly all patients rinsing with CAPHOSOL at least once daily.
A study of 55 gastrointestinal endoscopists found that 89.1% reported musculoskeletal pain, with severe pain affecting 47.3%. The study suggests different ergonomic mechanisms for symptom development based on experience level, highlighting the need for prevention and management strategies.
A recent study found that women and South Asians with typical pain were more likely to receive an incorrect diagnosis of angina pectoris. Despite this, they had lower rates of angiography and coronary interventions compared to men and white people. Patients with atypical chest pain also faced significant risks for cardiac disease.
A systematic review and meta-analysis found potential benefits of continuous wound infusions of local anaesthetics in reducing opioid consumption after laparotomy for major colorectal surgery. The study highlights the need for future research on this topic, including addressing methodological heterogeneity and cost-effectiveness analysis.
A study published in Annals of Internal Medicine found that massage therapy provided immediate benefits on pain and mood among patients with advanced cancer. The treatment improved symptoms greater than simple touch, offering a safe and effective way to provide immediate relief.
A study of 402 Parkinson's disease patients found that 69.9% experienced pain, compared to 62.8% in healthy controls. Pain types included cramping and central neuropathic pain, suggesting a link between brain structures and pain processing.
According to a landmark government study, nearly half of adults will develop painful knee osteoarthritis over their lifetime, with obesity being a major risk factor. The Arthritis Foundation recommends techniques such as weight control, exercise, and self-management programs to reduce pain and disability associated with arthritis.
A study published in Psychological Science found that socially painful experiences can be revisited through memory recall, causing increased emotional pain. In contrast, physically painful events tend to fade with time. The study's findings suggest an evolutionary aspect of human brain development, particularly in the cerebral cortex, ...
A US study found numerous errors in the testing process at family medicine clinics, with adverse consequences more common for minority patients. The research highlights the need for office-by-office improvements to mitigate these errors and reduce harm.
Despite a median waiting time of 8 months, 63% of patients preferred to stay with their current surgeon due to trust, reputation, and personal experience. This highlights the importance of addressing patient concerns in setting waiting-time guarantees.
A study of quarter of a million patients found epidural anaesthesia to be safe for intermediate to high-risk surgery, but only slightly improving survival rates. The procedure offers better postoperative pain relief and reduces surgical stress response.
A recent study by Harvard researchers found that coronary CTA is more cost-effective than current tests for diagnosing low-risk women with acute chest pain. The study suggests that CT angiography can reduce total healthcare costs by $380 and emergency department costs by $410 compared to standard care.
The Life Sciences Discovery Fund has awarded $5 million in grants to six Washington State-based organizations for innovative health research projects. These projects focus on prostate cancer imaging, safer in-home environments, recovery from brain damage, and more.
A recent study published in Academic Emergency Medicine found that using a 64-slice CT scanner to evaluate low-risk chest pain patients in the emergency room is more cost-effective than current standard of care. The study shows improved patient outcomes and reduced costs by avoiding overnight stays in observation units and cardiac stre...
A PhD study found that foreign wives in Taiwan often suffer low mental and physical health, as well as domestic violence and enter prostitution to make ends meet. The women, mostly from Vietnam and Indonesia, were difficult to reach due to their husbands' efforts to hide them from public view.
Researchers used fMRI scans to study children's responses to pain and found that their brains showed similar activation patterns to adults. The study also discovered additional brain regions activated when children saw someone intentionally hurt by another individual.
A study of newborn intensive care found that many painful procedures are performed without pain medication or therapy. Neonates experience high rates of repeated and prolonged pain exposure, which can alter their subsequent pain processing and behavior.
A topical spray has been shown to reduce pain in children undergoing intravenous procedures by 34%, improving success rates and procedure times. The study's findings have significant clinical implications, particularly for busy office practices or emergency departments.
Researchers found that sucrose reduces overall pain in newborns during painful medical procedures, but not for intramuscular injections or heel-lancing. The study's results will help update pain management guidelines to better reduce pain responses in newborns.
Researchers found that general anesthetics activate and sensitize specific receptors on neurons in the peripheral nervous system, increasing post-operative pain. The study suggests that this mechanism may be the reason why patients often experience increased discomfort after waking up from surgery.
A recent study found that nearly one in five patients experiences chest pain one year after having a heart attack. Patients who experienced chest pain were more likely to be younger, non-white males with prior chest pain, and had poorer health outcomes.
Currently used pain assessment tools may not accurately reflect the pain experience in infants. A study published in PLOS Medicine found that changes in brain activity correlated with clinical pain scores, but were more strongly linked to behavioral components such as facial expression than physiological components like heart rate. The...
Research shows that patients need to re-learn the sit-to-stand position technique after TKA, relying on a larger hip extensor movement. Physical therapists can help by teaching correct techniques, potentially preventing future knee osteoarthritis.
Researchers at the University of Montreal have established the cause of hereditary sensory and autonomic neuropathy type II, a severe disorder characterized by loss of sensation in limbs. The WNK1/HSN2 isoform has been identified as the underlying gene mutation, allowing for the development of animal models and potential pain treatments.
A study of ongoing randomized clinical trials in diabetes reveals that only 20% have primary outcomes important to patients, such as illness, pain, or death. The researchers emphasize the need for a standard set of patient-important outcomes in diabetes trials to improve their informativeness.
A randomized clinical trial found that oral prednisolone is clinically equivalent to naproxen in reducing pain and inflammation in patients with gout. The study suggests that prednisolone could be a safer alternative for treating gout, with potential economic benefits due to reduced healthcare costs.
Lubiprostone has been shown to significantly improve all IBS-C symptoms in women, including abdominal pain, bloating, and constipation severity. The drug is also effective in treating IBS-C for up to one year, with improved stool consistency and reduced nausea and diarrhea.
CAPHOSOL, an advanced electrolyte solution, has been shown to relieve oral mucositis and improve quality of life for cancer patients. The study found that 95% of patients reported favorable OM scores and high levels of patient and practitioner satisfaction with CAPHOSOL.
Researchers at Johns Hopkins Medicine have identified a gene, Pirt, that regulates a heat-activated molecular sensor, leading to variable pain sensitivity. The study found that mice lacking Pirt responded slower to heat and were less sensitive to capsaicin, suggesting Pirt's specific role in pain perception.
Researchers have discovered a timing mechanism in the brain of fruit fly larvae that controls their avoidance of food and could lead to new pain relief methods. This mechanism has counterparts in mammalian models involved in psychological processes such as food response, anxiety suppression, and pain perception.
Researchers found that using a cane significantly reduced the peak knee adduction moment, alleviating destructive load on affected knees. The study suggests that canes may be an effective short-term solution for knee OA patients.
A study published in Arthritis Care & Research reveals that obese patients undergoing revision total hip arthroplasty (THA) are at a higher risk of complications, including surgical site infections and dislocations. The research found a strong correlation between obesity and adverse events after revision THA.
A new study reveals that women are more likely to experience atypical symptoms such as nausea and jaw pain during a heart attack, leading to delayed treatment. Women were also less likely to receive life-saving treatments like beta blockers, statins, and angioplasty compared to men.
A study published in The Lancet found that nearly 30% of men and women reported feeling some level of pain at sampled times. People with lower incomes or less education spent more time in pain and had higher average pain ratings. Pain also imposes significant costs on the healthcare system, economy, and lost productivity.
A Princeton University survey found that 28% of Americans experience pain at any given moment, with those with less education and lower income spending more time in pain. The study also showed that pain can be a barrier to socializing, working, and overall well-being.
Researchers at NIMH found that brain activity responds to social hierarchy, influencing motivation and health. The ventral striatum activates equally for monetary rewards and changes in rank.
Research shows that preterm babies can recover from pain faster when given kangaroo mother care, reducing facial expressions of pain and recovery time. This approach could also have benefits for mothers whose parental role diminishes while their baby is in intensive care.
A study published in the April 2008 edition of the journal Phytotherapy Research found that Pycnogenol, an antioxidant plant extract from pine bark, significantly reduced osteoarthritis symptoms by 56% and joint pain by 55%. The treatment also improved physical function by 56% and increased patient mobility almost three-fold.
A recent study published in Arthritis Care and Research journal found that regular exercise, specifically the Arthritis Foundation Exercise Program, significantly improves and manages arthritis pain. Participants reported a decrease in pain and fatigue, an increase in upper and lower extremity function, and increased strength after par...
A recent survey of over 13,000 shoppers reveals that tightwads are more prevalent than spendthrifts due to the emotional pain associated with spending. Tightwads tend to save because forking out money is too painful an experience.
A review of published literature on women's expectations and experience of pain and pain relief in labour reveals a gap between expectations and reality. Most women underestimate the intensity of pain they will experience and may not be prepared for the possibility that they might need pain relief.
A provocative study by Dan Ariely found that a 10-cent pill is less effective at killing pain than a $2.50 pill, even when they are identical placebos. The study suggests that patients' subjective ratings of pain are influenced by the perceived quality and cost of medications.
A study by Ohio State University found no improvement in immune status, wound healing, or pain control among participants exposed to aromatherapy oils. However, lemon oil showed a positive effect on moods, while lavender oil had no impact.
Klaus Keller's research suggests that the North Atlantic meridional overturning circulation (MOC) may respond to human-made greenhouse gas emissions in a threshold response. Improved MOC observation systems could provide an early warning of an approaching collapse, enabling more effective climate policies.
Patients with larger social networks report less pain and anxiety before surgery, which can positively impact their recovery. Clinicians should be aware of the link between social networks and patient recovery after major operations.
A new study published in Arthritis Care & Research found that taking two NSAIDs was associated with lower scores on a health-related quality of life assessment. Dual use was also linked to worse physical functioning and symptoms, highlighting the need for better pain management and patient communication.
Women with irritable bowel syndrome (IBS) who experienced sexual and/or physical abuse may have a heightened brain response to pain, making them more sensitive to abdominal discomfort. Researchers found that patients with IBS background of abuse were less effective in turning off a pain modulation mechanism in the brain.
The American College of Physicians has issued new guidelines to improve palliative care at the end of life, focusing on pain, shortness of breath, and depression. The guidelines recommend regular assessment and use of proven therapies to manage these symptoms, with a focus on improving quality of care for patients with serious illnesses.
Recent studies in Annals of Internal Medicine reveal significant advancements in palliative care and insights into sickle cell disease's prevalence. Researchers also discovered a new strain of antibiotic-resistant Staphylococcal Infections primarily affecting men who have sex with men, emphasizing the need for targeted prevention measu...
Research at the University of Delaware found women with osteoarthritis in their knees have significantly reduced mobility and function compared to men. Women may need to become more educated about knee-replacement surgery risks and benefits to preserve their mobility and quality of life.
The study evaluated the Arthritis Foundation Exercise Program's effects on managing arthritis through exercise. The results showed significant improvements in pain, fatigue, and physical function, with continued benefits when participants maintained program participation at home.
A 20-minute evening back massage was found to decrease pain intensity and unpleasantness, as well as anxiety, in patients undergoing major surgery. The study suggests that massage may act through multiple mechanisms, including relieving anxiety and generating mood-boosting endorphins.
A new study by University of Iowa researcher Vera Loening-Baucke found that acute and chronic constipation accounted for nearly half of all cases of acute abdominal pain in children. The study recommends that physicians perform a simple rectal examination to diagnose constipation as a cause of abdominal pain.
A study found that many cancer patients with metastatic disease incorrectly believe opioids are only for dying patients. Morphine can improve pain management and quality of life for living patients. Experts stress the importance of professional confidence in opioid use to change these beliefs.
Researchers found that stress hormone noradrenaline suppresses pain inputs from the brainstem, reducing neurotransmitter launch and triggering nerve impulses. The study provides important mechanistic clues to understanding stress-induced analgesia.
A review of six knee osteoarthritis treatment guidelines found significant differences in recommended treatments, with a focus on acetaminophen, NSAIDs, and exercise. The study highlights the need for more detailed educational interventions to improve guideline applicability.
A double-blind study published in Nutrition Research reveals Pycnogenol improves physical function by 52 percent in patients suffering from OA. The antioxidant plant extract also controls inflammation and complements existing strategies for treating osteoarthritis.
A study led by Ronald Epstein found that doctors voiced empathy in only 15% of office visits, despite repeated prompting from patients. Patients reported high satisfaction when doctors empathized with them, especially in challenging situations.