Articles tagged with Sleep Disorders
Research suggests that during deep sleep, neurons representing related items fire in close temporal order, triggering synaptic plasticity and forming strong connections. This process strengthens or creates new relational memories, which can be essential for learning connections between objects or people.
A study conducted at Brigham and Women's Hospital found that a higher dose of melatonin (5mg) increased total sleep time compared to placebo in healthy older adults. The high-dose melatonin group showed significant improvements in both nighttime and daytime sleep episodes.
Researchers at the University of Bern have identified how the brain processes emotions during dream sleep. During REM sleep, the brain favors the discrimination of safety versus danger in the dendrites, but blocks the over-reaction to emotion, particularly danger. This decoupling is essential for optimizing survival and stability.
Researchers found that neuronal ensembles in the amygdala and prefrontal cortex existed before memory acquisition, but developed through experience in the hippocampus. The study also revealed that ensemble synchrony across brain regions was particularly strong during transient bursts of activity, suggesting a role in memory consolidation.
Researchers found high levels of mood disturbances and sleep disorders among COVID-19 patients, with increased fatigue increasing the risk of anxiety and depression. The study emphasizes the importance of addressing mental health issues in COVID-19 recovery.
Researchers at UCLA found that premenopausal women with low levels of anti-Mullerian hormone are at a higher risk of experiencing significant bone loss within two to three years. The study suggests that measuring AMH levels could help physicians identify women at risk and provide targeted treatment.
A study found that 25.3% of children with mild head injuries continue to suffer from persistent post-concussion syndrome for years, often misdiagnosed as ADHD or sleep disorders. The syndrome causes chronic symptoms like forgetfulness, memory problems, and sensitivity to light and noise.
Researchers found that a temporary increase in dopamine levels in the basolateral amygdala initiates transitions from non-rapid eye movement (NREM) to rapid eye movement (REM) sleep. This discovery may have important implications for understanding changes in sleep state and treating conditions like cataplexy and narcolepsy.
A recent study found that sleep bruxism can lead to temporomandibular joint disorders due to increased mechanical loading. The research discovered that specific combinations of tooth shape and location during grinding significantly impact the risk of TMJ problems.
The SynGAP Research Fund has developed a pre-screening tool to identify potential SYNGAP1 patients through a free online survey. The partnership with Probably Genetic aims to screen undiagnosed patients and provide them with genetic testing resources, ultimately advancing treatment development for SYNGAP1.
Researchers found that the master clock and slave clock operate via distinct molecular mechanisms, allowing for robustness and flexibility in regulating bodily rhythms. The master clock's ability to adapt to environmental changes enables quick adjustment to new time zones after international flights.
Research reveals that people who have had COVID-19 are more likely to experience mental health problems, including anxiety, depression, and substance use disorders, within a year after recovery from the virus. The study found that COVID-19 survivors were 60% more likely to suffer from mental health problems than those who were not infe...
A VA research team found increased risks of mental health disorders, including depression, anxiety, and sleep disorders, in individuals who had COVID-19 infection. The study analyzed medical records of nearly 154,000 patients with COVID-19 and compared them to over 11 million people without COVID-19.
Researchers at GIST demonstrate that ultrasound pulses can reduce β-amyloid plaque concentration and tau protein levels in AD-model mice, suggesting a promising non-invasive therapeutic strategy. The treatment also improves brain connectivity without causing harm to brain tissue.
Researchers found that prenatal exposure to nicotine and its by-products produces long-term effects on sleep and stress-response in mice. This early-life exposure can lead to alterations in the hippocampus, a sensitive structure that develops after birth.
New research by Northwestern University found that reactivating memories during sleep significantly improves face-name learning. The study also discovered that uninterrupted deep sleep is crucial for this improvement.
Researchers found that EEG arousal intensity varies by respiratory event type and severity in OSA, affecting sleep disruption. The study reveals distinct patterns of gamma power during arousals from different types of respiratory events, such as obstructive apnoeas and hypopnoeas with varying degrees of blood oxygen desaturation.
Researchers at the University of Eastern Finland have developed simpler measurement technologies for diagnosing sleep disorders, enabling more accurate analyses. The new methods use reusable sensors in home environments, reducing costs and increasing patient comfort.
A study published in the European Respiratory Journal found that people with both insomnia and obstructive sleep apnoea are at a higher risk of heart problems and mortality. Participants with co-morbid insomnia and sleep apnoea were two times more likely to have high blood pressure and 70% more likely to have cardiovascular disease.
A study by Brigham and Women's Hospital found that eating during the nighttime can lead to glucose intolerance due to a misalignment between central and peripheral circadian clocks. In contrast, limiting meals to the daytime maintains internal circadian alignment and prevents glucose intolerance in shift workers.
A small clinical trial found that eating during the nighttime increased glucose levels, while restricting meals to the daytime prevented this effect. The study suggests that better alignment between internal and external circadian rhythms may drive these benefits.
A new study published in Diabetologia found that later bedtime routines and poor quality of sleep are associated with higher blood glucose levels and poorer control of blood sugar following meals. Longer sleep periods were linked to better control, while more efficient sleep was also beneficial.
The study found that people with sleep disorders had the highest rates of type 2 diabetes, with 40% of subjects having the disease. Prevalence of T2D was lower among individuals with intellectual disability, with only 8% having the disease.
A new Cleveland Clinic study found that patients with certain sleep disorders have a 31% higher rate of hospitalization and mortality from COVID-19. The research team analyzed retrospective data from 5,400 patients and found that sleep-related hypoxia translates to worse COVID-19 outcomes.
The November issue of CHEST journal includes 69 articles on topics such as asthma, COPD, critical care and thoracic oncology. The journal also offers complementary web and multimedia activities to expand the reach of its research.
Research suggests COVID-19 pandemic has adverse effects on women's menstrual cycles due to stress and sleep disturbance. Women are experiencing increased rates of depression, anxiety, and poor sleep.
Researchers at Skoltech propose a method for interpreting brain activity data that is up to five times more accurate than the conventional technique. This method can help treat drug-resistant epilepsy and understand cognitive processes in the healthy brain.
A study of 75 FIFO shift workers found significant sleep loss and reduced alertness, with up to 60% at risk of developing sleep disorders. The research highlights the need for companies to reassess roster designs to ensure adequate rest and provide education on good sleep health practices.
Scientists have identified specific peptides in milk that relieve stress and enhance sleep. The study found that one of these peptides, YPVEPF, increased sleep duration by over 400% in mice.
A recent study published in PLOS Medicine found that people with mental illnesses have poorer sleep quality compared to the general population. The study analyzed data from 89,205 participants and discovered significant differences in sleep patterns, including increased waking frequency and duration.
Researchers will investigate hidden signs of brain damage in REM behavior disorder, aiming to identify biomarkers that predict impending neurological disease. The goal is to delay the onset or prevent dementia or Parkinsonism through clinical trials.
Researchers visualize key proteins in Drosophila brains, revealing their daily oscillations and spatial organization. The study highlights the importance of clock proteins in regulating circadian rhythms, which control sleep-wake cycles, metabolism, and cancer risk.
Researchers at Rice University and the US Army are developing a portable skullcap that analyzes cerebrospinal fluid flow during sleep to clear metabolic waste. The goal is to noninvasively measure and modulate brain health in soldiers, potentially treating sleep disorders in real time.
A study of nearly 12,000 kids found that screen time is only slightly linked to attention disorders, disturbed sleep, and lower grades. However, excessive screen time may have social benefits, with kids who spent more time with screens having more close friends.
A new study from Brigham and Women's Hospital found significant racial-ethnic differences in sleep health, with white adults having the best sleep outcomes and Black adults facing the worst. The research used data from over 1,700 adults and identified factors such as irregular timing and duration, insufficient sleep duration, and high ...
A recent study published in SLEEP found that teenagers who slept only five hours per night experienced significant depression, anger, and confusion. In contrast, those who slept ten hours reported increased happiness. The study highlights the importance of sufficient sleep for adolescents to mitigate mood deficits.
Researchers found that sleepwalkers show an elevated rest-and-digest response and a lower fight-or-flight response during deep sleep. This discovery paves the way for new understanding of the phenomenon and potential treatments for sleepwalking.
Researchers discovered that consuming concentrated chocolate in the morning can aid in burning fat and decreasing blood sugar levels. The study also found that eating chocolate at different times of day can influence hunger, appetite, microbiota composition, sleep, and metabolism.
Researchers detected changes in fractal motor activity regulation (FMAR) patterns in cognitively healthy adults, particularly among women, which were associated with preclinical Alzheimer's disease pathology. FMAR may serve as a non-invasive biomarker for testing and screening AD.
Dr. Charlene Gamaldo receives inaugural Diversity, Equity and Inclusion Leadership Award for her efforts to increase diversity in sleep medicine and close health disparities. The award is presented by the Associated Professional Sleep Societies, a joint initiative of American Academy of Sleep Medicine and Sleep Research Society.
A study of over 700,000 TBI patients found that those with sleep disorders had a 25% higher risk of developing dementia. The risk was similar for male and female patients, highlighting the importance of targeted awareness about sleep disorders in TBI patients.
Patients with REM sleep behavior disorder show signs of low blood flow and cognitive decline, suggesting a link between disrupted sleep and Parkinson's symptoms. The study aims to investigate the relationship between reduced blood flow and Parkinson's disease progression.
A new study reveals that sleep disorders are a common symptom of multiple system atrophy, with greater severity correlating to more neuronal damage. The research found specific associations between sleep-related symptoms and MSA severity, including the parkinsonism subtype.
Researchers from the University of Tsukuba found that vigorous exercise enhances sleep quality despite lack of subjective change. Exercise improves slow-wave sleep stability, which may lead to new treatment recommendations for sleep disorders.
A recent study published in eLife reveals that astrocytes, a type of glial cell, can independently promote longer or deeper sleep in mice by manipulating slow-wave activity. The findings suggest that targeting astrocytes could lead to new insights into sleep disorders and brain diseases linked to sleep disturbances.
Researchers investigated dynamic changes to DNA methylation in shift workers, finding that rest and recovery can restore gene function. The study suggests that insufficient sleep and related inflammatory consequences may mediate shift work disorder, highlighting the importance of sufficient rest for overall health.
Visually impaired athletes are at higher risk for sleep disorders due to stress from competition activities and late wake-up times. Researchers found that approximately one-third of respondents had sleep disorders, highlighting the need for strategies to improve relationships and adjust wake-up times.
Children with epilepsy experience poorer sleep quality, disruptions, and parasomnias compared to healthy peers. Integrating sleep assessments into diagnosis and management could reduce seizures' impact on sleep and overall quality of life.
Researchers found a significant association between sleep disorders and symptoms of burnout among faculty and staff. The study suggests that addressing sleep issues may be crucial to mitigating physician burnout.
A study by researchers at UC Santa Cruz reveals the molecular mechanisms behind the 'night owl' sleep disorder, which affects one in 75 people of European descent. The genetic mutation identified alters a key component of the biological clock, causing people to stay up late and sleep in late.
Researchers found a connection between contact sports participation and chronic traumatic encephalopathy (CTE) leading to sleep dysfunction. The study revealed that tau pathology in brainstem nuclei is more strongly associated with sleep symptoms than Lewy body pathology, suggesting a new link between CTE and REM sleep behavior disorder.
Research reveals that losing sleep leads to increased anger and frustration over time. Well-slept individuals adapt better to stressful situations, whereas sleep-restricted individuals exhibit higher anger in response to aversive stimuli.
Researchers found a statistically significant increase in adverse medical events following the spring time change, with a 18% rise in human error-related incidents. The study suggests that sleep loss caused by the time change may contribute to this risk.
A new study suggests that following an alternate Mediterranean or Alternative Healthy Eating Index diet pattern may be linked to fewer non-motor symptoms such as constipation, daytime sleepiness and depression. The researchers found a strong relationship between healthy diet adherence and reduced risk of these preceding symptoms.
Fruit flies sleep more when unable to fly, adapting to challenging situations. Sleep helps animals respond effectively, according to researchers at WashU Medicine.
Scientists at Duke-NUS Medical School have discovered a potential therapeutic target for treating sleep disorders. Targeted mutations in the PER2 protein can alter the balance of the biological clock and significantly lengthen the circadian period in preclinical models.
Researchers found that a genetic mutation in the KCC2 protein causes a glitch in brain activity suppression, leading to panic responses and seizures. The R952H variant has been linked to individuals with autism spectrum disorder, epilepsy, and schizophrenia.
Researchers often overlook comorbidities in Tourette syndrome, but it is an intersection of multiple medical conditions. A multidisciplinary approach is necessary for effective treatment and patient evaluation.
A study by Anglia Ruskin University found that sleep disturbance is common among young children with neurodevelopmental disorders, including Down's syndrome, Fragile X syndrome, and Williams syndrome. The research showed that improved sleep patterns were associated with better language skills in these children.
Research in rats reveals that brain-wave bursts, like earthquakes, are necessary for healthy sleep. These non-equilibrium dynamics and criticality underlie sleep micro-architecture, governing spontaneous transitions between sleep stages.