Articles tagged with Sleep Disorders
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Researchers found abnormal 12-hour gene activity cycles in postmortem brains of patients with schizophrenia. The study identified altered timings of neural connections and mitochondrial function, suggesting potential underlying causes for behavioral abnormalities.
Insufficient sleep during teenage years is linked to a higher risk of developing multiple sclerosis (MS). Short sleep duration and poor sleep quality are associated with a 40% and 50% increased risk, respectively. The study suggests that sufficient restorative sleep may be an important preventive factor against MS.
A recent study published in Science Advances has deepened the understanding of circadian rhythm regulation in mammals. The research found that intracellular cyclic adenosine monophosphate (cAMP) is controlled by a neural network, whereas calcium ions are regulated by intracellular mechanisms.
Long COVID is a systemic condition with over 100 reported symptoms, including fatigue, anxiety, and breathing issues. Treatment focuses on symptom management through structured programs and guideline-directed mental health supports.
The American Thoracic Society will host ATS 2023 in Washington, DC from May 21-24. The event will cover the latest developments in pulmonary, critical care, and sleep medicine. Register now to attend or access recorded sessions.
Researchers at Osaka Metropolitan University found that closed-eye perception of brightness is remarkably stronger than previously reported, with values up to 10 times higher. The color of the light also affects perception, with red being perceived as brighter and blue as darker.
A nasal spray has shown promising results in treating obstructive sleep apnea by preventing airway narrowing during sleep. The treatment, which targets specific receptors on the upper airways, improved airway stability and was well-tolerated in a small clinical trial.
Wild geese in Germany, Denmark, and the Netherlands experience significant changes in their behavior after fireworks, including flying further and foraging more, even after the disturbances end. The effects persist for up to two weeks, with birds leaving their sleeping sites and flying hundreds of kilometers non-stop.
A recent study found that benzodiazepine treatment for sleep disorders is associated with an increased risk of drug overdose among young people aged 10-29, particularly those with recent opioid prescriptions. This highlights the importance of considering alternative pharmacologic treatments to minimize safety risks.
Researchers found that people living with HIV have a significantly delayed internal body clock, consistent with the symptoms of jet lag. This disruption may contribute to increased health problems experienced by those with HIV. The study suggests a strong need for further research on younger people living with HIV in other countries.
Recent studies have shed light on the biological mechanisms that connect sleep and anxiety, highlighting the importance of sleep in regulating stress responses. Research has shown that inadequate sleep can lead to increased anxiety and stress, while also exacerbating mental distress.
A study by Beth Israel Deaconess Medical Center found that divisive political events negatively influence factors related to public mood, well-being, and alcohol consumption. Participants reported reduced sleep quality, increased stress, negative mood, and higher alcohol use in the days leading up to the election.
A randomized controlled trial found that oral ENT-01 significantly improves constipation and possibly neurological symptoms in persons with Parkinson disease. The treatment is safe for up to 25 days, with a dose-dependent effect that persists beyond the treatment period.
A new study from the University of Ottawa reveals that morning types tend to have superior verbal ability, contrary to previous research suggesting that evening types have an advantage. The study found that accounting for factors like bedtime and age, morning individuals outperformed their evening counterparts in verbal intelligence.
A new study published in PLOS ONE found that chronic pain at age 44 is associated with poor mental health outcomes, joblessness, and general health issues in later decades. The research also suggests a link between chronic pain and COVID-19 infection, highlighting the need for attention to chronic pain as a public health concern.
A study by Ural Federal University found that daytime naps and wakefulness both reinforce the formation of fear memories in response to emotional trauma. This research has significant implications for developing strategies for rehabilitating individuals with anxiety disorders.
Researchers found that playing a sound associated with a positive daytime experience during sleep can reduce nightmare frequency and increase emotional positivity in dreams. The study's findings support the development of new therapies for treating nightmares, which affect up to 4% of adults.
Researchers found that autistic women are more vulnerable to psychiatric conditions and hospitalization than men, with a higher risk of depression, anxiety disorders, and self-harm. The study suggests that healthcare needs to be expanded for young adults, especially autistic women, to detect mental illness in time.
A new study found that sleeping five hours or less per night is associated with a higher risk of developing at least two chronic diseases over a 25-year period. This includes heart disease, cancer, and diabetes. The study analyzed data from over 7,000 men and women aged 50, 60, and 70.
A two-week intervention targeting the circadian system helped shift teens' bedtime by an hour and a half earlier, increasing total sleep time by approximately an hour. The study also found improved concentration, reduced irritability, and better morning alertness in participants.
A machine learning model developed by Carnegie Mellon University can accurately predict how stay-at-home orders affect people with multiple sclerosis. The model uses passively gathered smartphone and fitness tracker data to identify factors that signal changes in health.
Researchers found that getting enough sleep influences the environment where monocytes form, develop, and get primed to support immune function. This process, hematopoiesis, occurs in the bone marrow and can accelerate clonal hematopoiesis, an age-related condition linked to cardiovascular disease.
Researchers used data from over 400,000 individuals to model genetic and environmental factors influencing common neuropsychiatric disorders. Gene-environment interactions accounted for a significant proportion of variability in some disorders, while others showed more substantial contributions.
A new study published in Frontiers found that excessive blue light exposure can alter cellular functions in fruit flies, potentially leading to accelerated aging. The researchers discovered changes in metabolites essential for cell function and communication between neurons.
The American Heart Association offers important guidance on sleep-disordered breathing and its association with cardiac arrhythmia, highlighting the potential benefits of SDB treatment on patient outcomes. The statement emphasizes the need for more randomized data to confirm the link between SDB and reduced atrial fibrillation recurrence.
A study by Tel Aviv University researchers found a unique oral microbiotic signature in the saliva of veteran soldiers with PTSD, which may help diagnose post-traumatic stress disorder objectively. The study also showed that people with PTSD exhibit the same picture of bacteria in their saliva as those who have experienced combat stres...
The August issue of the CHEST journal features 47 articles on clinically relevant topics such as asthma, COPD, and pulmonary vascular disease. A highlighted article examines barriers to palliative care in interstitial lung disease.
A new study published in Neurobiology of Sleep and Circadian Rhythms found that shift work can lead to long-lasting health effects, including increased severity of strokes. The research, led by Texas A&M University, suggests that disrupted internal body clocks can alter gut and brain interactions, leading to worse stroke outcomes.
A study led by Imperial College London researchers discovered that certain types of stress induce sleep in mice, which subsequently relieves anxiety. The findings suggest that a specific set of neurons detected and responded to stress hormone levels, inducing both NREM and REM sleep.
A first-of-its-kind study from the University of Pennsylvania School of Nursing investigated the use of novel graduate-level sleep education curriculum for primary care nurse practitioners. The program positively impacted a range of learning outcomes, including improved recognition and evaluation of sleep disturbances and disorders.
The study found increases in screen time, alcohol use, and poor sleep among Australian girls during the pandemic. However, overall sleep improved, and some dietary choices improved during lockdown.
Research suggests that during deep sleep, neurons representing related items fire in close temporal order, triggering synaptic plasticity and forming strong connections. This process strengthens or creates new relational memories, which can be essential for learning connections between objects or people.
A study conducted at Brigham and Women's Hospital found that a higher dose of melatonin (5mg) increased total sleep time compared to placebo in healthy older adults. The high-dose melatonin group showed significant improvements in both nighttime and daytime sleep episodes.
Researchers at the University of Bern have identified how the brain processes emotions during dream sleep. During REM sleep, the brain favors the discrimination of safety versus danger in the dendrites, but blocks the over-reaction to emotion, particularly danger. This decoupling is essential for optimizing survival and stability.
Researchers found that neuronal ensembles in the amygdala and prefrontal cortex existed before memory acquisition, but developed through experience in the hippocampus. The study also revealed that ensemble synchrony across brain regions was particularly strong during transient bursts of activity, suggesting a role in memory consolidation.
Researchers found high levels of mood disturbances and sleep disorders among COVID-19 patients, with increased fatigue increasing the risk of anxiety and depression. The study emphasizes the importance of addressing mental health issues in COVID-19 recovery.
Researchers at UCLA found that premenopausal women with low levels of anti-Mullerian hormone are at a higher risk of experiencing significant bone loss within two to three years. The study suggests that measuring AMH levels could help physicians identify women at risk and provide targeted treatment.
A study found that 25.3% of children with mild head injuries continue to suffer from persistent post-concussion syndrome for years, often misdiagnosed as ADHD or sleep disorders. The syndrome causes chronic symptoms like forgetfulness, memory problems, and sensitivity to light and noise.
Researchers found that a temporary increase in dopamine levels in the basolateral amygdala initiates transitions from non-rapid eye movement (NREM) to rapid eye movement (REM) sleep. This discovery may have important implications for understanding changes in sleep state and treating conditions like cataplexy and narcolepsy.
A recent study found that sleep bruxism can lead to temporomandibular joint disorders due to increased mechanical loading. The research discovered that specific combinations of tooth shape and location during grinding significantly impact the risk of TMJ problems.
The SynGAP Research Fund has developed a pre-screening tool to identify potential SYNGAP1 patients through a free online survey. The partnership with Probably Genetic aims to screen undiagnosed patients and provide them with genetic testing resources, ultimately advancing treatment development for SYNGAP1.
Researchers found that the master clock and slave clock operate via distinct molecular mechanisms, allowing for robustness and flexibility in regulating bodily rhythms. The master clock's ability to adapt to environmental changes enables quick adjustment to new time zones after international flights.
Research reveals that people who have had COVID-19 are more likely to experience mental health problems, including anxiety, depression, and substance use disorders, within a year after recovery from the virus. The study found that COVID-19 survivors were 60% more likely to suffer from mental health problems than those who were not infe...
A VA research team found increased risks of mental health disorders, including depression, anxiety, and sleep disorders, in individuals who had COVID-19 infection. The study analyzed medical records of nearly 154,000 patients with COVID-19 and compared them to over 11 million people without COVID-19.
Researchers at GIST demonstrate that ultrasound pulses can reduce β-amyloid plaque concentration and tau protein levels in AD-model mice, suggesting a promising non-invasive therapeutic strategy. The treatment also improves brain connectivity without causing harm to brain tissue.
Researchers found that prenatal exposure to nicotine and its by-products produces long-term effects on sleep and stress-response in mice. This early-life exposure can lead to alterations in the hippocampus, a sensitive structure that develops after birth.
New research by Northwestern University found that reactivating memories during sleep significantly improves face-name learning. The study also discovered that uninterrupted deep sleep is crucial for this improvement.
Researchers found that EEG arousal intensity varies by respiratory event type and severity in OSA, affecting sleep disruption. The study reveals distinct patterns of gamma power during arousals from different types of respiratory events, such as obstructive apnoeas and hypopnoeas with varying degrees of blood oxygen desaturation.
Researchers at the University of Eastern Finland have developed simpler measurement technologies for diagnosing sleep disorders, enabling more accurate analyses. The new methods use reusable sensors in home environments, reducing costs and increasing patient comfort.
A study published in the European Respiratory Journal found that people with both insomnia and obstructive sleep apnoea are at a higher risk of heart problems and mortality. Participants with co-morbid insomnia and sleep apnoea were two times more likely to have high blood pressure and 70% more likely to have cardiovascular disease.
A study by Brigham and Women's Hospital found that eating during the nighttime can lead to glucose intolerance due to a misalignment between central and peripheral circadian clocks. In contrast, limiting meals to the daytime maintains internal circadian alignment and prevents glucose intolerance in shift workers.
A small clinical trial found that eating during the nighttime increased glucose levels, while restricting meals to the daytime prevented this effect. The study suggests that better alignment between internal and external circadian rhythms may drive these benefits.
A new study published in Diabetologia found that later bedtime routines and poor quality of sleep are associated with higher blood glucose levels and poorer control of blood sugar following meals. Longer sleep periods were linked to better control, while more efficient sleep was also beneficial.
The study found that people with sleep disorders had the highest rates of type 2 diabetes, with 40% of subjects having the disease. Prevalence of T2D was lower among individuals with intellectual disability, with only 8% having the disease.
A new Cleveland Clinic study found that patients with certain sleep disorders have a 31% higher rate of hospitalization and mortality from COVID-19. The research team analyzed retrospective data from 5,400 patients and found that sleep-related hypoxia translates to worse COVID-19 outcomes.
The November issue of CHEST journal includes 69 articles on topics such as asthma, COPD, critical care and thoracic oncology. The journal also offers complementary web and multimedia activities to expand the reach of its research.
Research suggests COVID-19 pandemic has adverse effects on women's menstrual cycles due to stress and sleep disturbance. Women are experiencing increased rates of depression, anxiety, and poor sleep.
Researchers at Skoltech propose a method for interpreting brain activity data that is up to five times more accurate than the conventional technique. This method can help treat drug-resistant epilepsy and understand cognitive processes in the healthy brain.
A study of 75 FIFO shift workers found significant sleep loss and reduced alertness, with up to 60% at risk of developing sleep disorders. The research highlights the need for companies to reassess roster designs to ensure adequate rest and provide education on good sleep health practices.
Scientists have identified specific peptides in milk that relieve stress and enhance sleep. The study found that one of these peptides, YPVEPF, increased sleep duration by over 400% in mice.