Articles tagged with Traumatic Injury
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study by Mass General Brigham found that individuals with traumatic brain injury and their caregivers consider recovery of basic communication an 'acceptable' outcome, challenging traditional assumptions about what constitutes a 'favorable' recovery. The study highlights the need for person-centered approaches to TBI outcome research.
A clinical prediction model called the Goliat score can estimate the risk of acute complications in patients with minor and moderate traumatic brain injuries. The model, developed by researchers at UOC and IRBLleida, uses easily accessible variables to predict neurological or cardiorespiratory complications and mortality within 48 hours.
A study published in Neurology found that taking antidepressants after a traumatic brain injury (TBI) is not associated with an increased risk of death, brain surgery, or longer hospital stays. The study included over 54,000 participants and found that antidepressant users had an 11% lower risk of needing emergency brain surgery.
Adverse experiences throughout life increase dementia and stroke risks, with depression as a mediating factor. Implementing life-course interventions addressing psychological trauma and mental health can reduce neurovascular disease burden.
A comparative effectiveness study found that SGLT2 inhibitors were associated with a lower risk of chronic kidney disease and acute kidney injury compared to GLP-1 receptor agonists. These findings suggest that SGLT2 inhibitor treatment may be an effective strategy for preventing kidney disease in individuals with type 2 diabetes.
A study of over 500 survivors found severe psychological trauma with somatic symptoms persisting decades after the attack. The results highlight the need for culturally sensitive mental health services, compensation, and ongoing care for chemical attack survivors.
A fully biodegradable, self-powered implantable electrical stimulation system was developed to address the challenge of effective muscle regeneration. The device combines degradable materials and in situ electrical stimulation intervention, overcoming key limitations of conventional electrical stimulators.
A recent editorial cautions that Canada's health systems may struggle to cope with the influx of patients during the upcoming FIFA World Cup. The article highlights concerns about overburdened hospitals and emergency departments, as well as the need for a national plan to bolster capacity and train personnel.
Researchers developed a wearable Revoice device that decodes speech signals and emotional cues to enable seamless real-time communication in people with post-stroke dysarthria. The device achieved a word error rate of 4.2% and sentence error rate of 2.9%, showing promising results for stroke rehabilitation.
A cohort study found a 9-fold increased risk of suicide in Norwegian patients discharged alive after critical injury. Follow-up is recommended for possible psychological distress in this patient group.
Researchers seek to improve burn trauma care by targeting a signaling kinase enzyme with a new-generation inhibitor. The goal is to reduce opioids needed for pain relief and scarring, improving patient recovery from trauma injury.
The new program combines limb preservation, amputation care, and reconstructive solutions like osseointegration to improve identity, functional outcome, and quality of life for patients. Patients will receive coordinated, personalized, and expert care that supports their recovery and promotes sustained overall health.
A study analyzing personal injury claims data for England and Wales found that mental trauma succeeds 1 in 7 dog-related injuries, resulting in the need for time off work and/or loss of earnings. Most incidents occurred in public spaces, with unrestrained dogs being a common cause.
This cohort study found that exposure to Migrant Protection Protocols was associated with higher rates of trauma during migration among asylum seekers. The Migrant Protection Protocols may have potential downstream implications for U.S. public health and security, including adverse health outcomes for asylum seekers.
A simulation study forecasted potential injury reductions in the US with AV adoption, suggesting a possible decrease in road traffic injuries. However, predicted confidence intervals remain broad, and no scenario reduced injuries outside of these bounds.
A new UK-based study found that adults who experience a head injury face a substantially higher risk of attempting suicide compared to those without such injuries. The 20-year population-based matched cohort study analyzed data from over 1.8 million adults and found that people with head injuries were 21% more likely to attempt suicide.
Researchers found that early communication between three pairs of brain regions is associated with favorable six-month functional outcomes. The study identified signature patterns in resting-state functional MRI data that can strengthen standard prognostic methods for assessing outcomes after moderate-to-severe brain injury.
Scientists at Salk Institute find protein CCN1, secreted by astrocytes, maintains stable neural circuits in adult brains. The discovery could lead to new therapeutics for brain injury and stroke.
Researchers at UVA Health System discover how traumatic brain injury increases Alzheimer's risk and find a potential prevention strategy using a hollowed-out virus to deliver repair supplies. The approach could help limit neurodegeneration and potentially prevent other neurological diseases.
A new study using mice found that surviving cells compensate for cell death by sprouting extra branches to promote recovery in the visual brain system. However, female mice showed delayed or incomplete repair compared to males. This suggests a compensatory mechanism following brain injury that differs between sexes.
Research shows that 77% of severely injured children are transported or transferred to pediatric trauma centers, highlighting the need for improved access and evidence-based strategies. Variability in access exists across Canadian provinces, with some areas having higher access than others.
Researchers at SwRI and Trinity University are working on a new prodrug to mitigate ischemia/reperfusion injury (IRI), which causes permanent cellular and tissue damage. The team aims to protect against IRI by targeting protein misfolding during cellular stress.
Researchers at Pitt and UPMC Children's Hospital discovered a biomarker of complicated pediatric traumatic brain injury, which may serve as dynamic indicators of post-injury recovery. The study found that children with TBI had a different epigenetic profile compared to those with orthopaedic injuries.
A new study analyzing over 5,000 homicide victim autopsies in Maryland found that a small but significant number of deaths could have been prevented with Stop the Bleed training. The program teaches bystanders how to apply pressure, pack wounds, and use tourniquets to control bleeding.
A new study found that fragmented sleep worsens symptoms of traumatic brain injury and decreases rapid-eye-movement (REM) sleep. Injured mice failed to compensate for lost REM sleep, leading to increased fatigue and decreased activity. The research highlights the critical role of uninterrupted sleep in brain injury recovery.
Victims of intimate partner violence with suicidal behavior show distinct injury patterns on medical imaging, including head, face, neck and upper limb injuries. The study aims to improve screening and intervention for vulnerable populations.
Creating a safe space free from body shaming is key to minimising female athletes' future risks of injury and protecting their health. The FAIR Consensus Statement provides practical recommendations for promoting gender-specific supportive environments in sports.
The study found significant differences in injury patterns between men and women, with men experiencing more ACL tears and women more frequent meniscal and MCL tears. These findings can help radiologists tailor imaging protocols and risk assessments to optimize patient outcomes.
Researchers found that treatment within one week of a serious head injury can reduce the risk of developing Alzheimer's disease. A study analyzing health records from over 100 million US patients showed a significant reduction in Alzheimer's risk at three and five years for those who received immediate treatment.
An international team led by Lehigh University researcher Hannah Dailey is building predictive models to understand and eventually prevent bone healing complications. The team aims to incorporate biological differences into the model, using a library of imaging data from Switzerland's AO Research Institute Davos.
Researchers at the University of Virginia Health System are exploring the role of the neurovascular unit in maintaining healthy brain function and how damage can cause chronic health conditions. The studies aim to identify new biomarkers for blast-related brain injury and develop strategies for prevention and treatment.
The European Society of Endocrinology has published a revised clinical practice guideline for the treatment of chronic hypoparathyroidism in adults, featuring a new definition and treatment algorithm. The guidelines aim to provide practical guidance for healthcare providers involved in diagnosing and managing the condition.
Researchers have summarized recent breakthroughs in theranostic nanomaterials, engineered nanoparticles that can both diagnose and treat TBI. These materials can deliver drugs precisely where damage occurs while monitoring biological changes inside the brain.
The URI team developed a cost-effective, easy-to-use tabletop device to generate pressure waves mimicking blasts that cause neurodegeneration. The device helps researchers study the development and progression of neurodegenerative diseases, including TBI-related neurodegenerative disease.
Researchers at UTA are exploring the potential of zinc to protect and regenerate muscle tissue damaged by trauma, with a focus on reducing secondary damage. The study uses a zinc-infused gel to promote muscle regeneration following blast injuries and aims to identify a safe and convenient way to apply zinc directly to muscle tissue.
A conservative dialysis approach resulted in faster and more complete kidney function recovery in patients with acute kidney injury. The study's findings suggest that this strategy could be a viable option for treating dialysis-requiring AKI, warranting further investigation.
The updated guidelines call for structured follow-up, early referral to rehabilitation, and attention to cognitive, mood, and functional changes after TBI. Health professionals are urged to screen all TBI patients for health-related social needs, such as food, housing, transportation, and financial insecurity.
A new study published in Science finds CTE shares genetic similarities with Alzheimer's disease, including DNA damage and tau protein buildup in the brain. Researchers used single-cell genome sequencing to identify somatic mutations in neurons from patients with CTE, revealing abnormal patterns of damage similar to those seen in AD.
Researchers found distinct brain features in football players, including shallower left superior frontal sulci and wider left occipitotemporal sulci, which may indicate increased risk of chronic traumatic encephalopathy (CTE). The study's findings could lead to the development of early detection tests and therapies.
Researchers from USC Neurorestoration Center and Caltech created a simple, noninvasive device using laser technology to measure brain blood flow. The tool has already been tested with humans in small proof of concept studies demonstrating its utility for assessing stroke risk and detecting brain injury.
Post-traumatic vasospasm (PTV) is a sudden narrowing of brain arteries that can lead to stroke and long-term neurological damage. Early diagnosis using tools like transcranial Doppler ultrasound and S100 protein blood tests is crucial to prevent secondary brain injury.
Researchers found that nearly all patients (94.8%) had at least one legal need, with income support being the most frequent. The Recovery Legal Care program helped secure $1.2 million in payments to patients, aiming to disrupt cycles of violence by stabilizing housing, food access, and employment.
A significant increase in pickleball-related ocular injuries has been reported among patients presenting to emergency departments. Eye protection guidelines are not currently in place, highlighting the need for standardized measures to reduce the risk of such injuries.
Researchers discovered that triggering a reversible, hibernation-like hypothermic state in male mice improved motor performance and preserved neural health following brain injury. The study found less neuroinflammation and improved neuron survival in the injured brain area.
A study of 40 women with PTSD following recent sexual assault trauma found a marked reduction in brain synchronization between the amygdala and prefrontal cortex. This disruption may be a biological signature of the disorder rather than a state-dependent marker, potentially leading to personalized treatment response.
Researchers introduced refinements to a rarely used surgical method, the reverse homodigital dorsoradial flap, for radial thumb defects. The key refinements preserved subcutaneous tissue for venous drainage and left a buffer zone at the arterial pivot point to reduce stress on blood vessels.
A cohort study found that early extracranial surgery was associated with adverse outcomes in function, cognition, and disability after moderate-severe traumatic brain injury. The study suggests that further research is needed to determine if surgical timing or other interventions can improve long-term deficits.
Researchers have made significant strides in understanding post-traumatic epilepsy (PTE), but a therapy to prevent its development remains elusive. Studies identify key barriers, including collaboration, funding, and standardization, and propose eight recommendations to advance PTE research. Potential therapies include disease modifica...
Two studies reveal that adult pedestrians suffer more severe injuries than children in motor-vehicle accidents, with adults experiencing higher mortality rates and complications. Researchers hope to identify 'hotspots' of accidents using geocoding and advocate for community changes to prevent future crashes.
Death rates from unintentional injury related to drug use increased by nearly 60% from 2018 to 2023. Middle-aged adults, particularly those aged 35-44, were found to be at higher risk of death from drug-induced accidental injuries.
A study by the American College of Surgeons found that AI enhanced evacuation efficiency, optimized routes, and prioritized patients by injury severity. AI also accelerated drug delivery, identified new treatments for injuries, and supported artificial limb selection.
A recent study published in the British Journal of Sports Medicine found that vision therapy can effectively treat concussion-related eye coordination disorders, including convergence insufficiency and accommodation insufficiency. Nearly 90% of patients in the treatment group were able to see normally after 12 weeks of therapy.
A new study examines the radiology department's experience during a mass casualty terror attack in southern Israel. Researchers found that rapid staff mobilization, versatile imaging resources management, and AI-enabled safety checks were crucial in guiding clinical decisions.
Research presented at the American Academy of Pediatrics 2025 National Conference & Exhibition found nearly half of pediatric golf cart injuries occurred in children under 12. The most common injuries were superficial lacerations and abrasions, with younger children experiencing head, face, and neck injuries.
The study, published in The BMJ, provides detailed data on traumatic injuries and medical conditions seen by healthcare workers in Gaza. It highlights the urgent need for resilient surveillance systems to inform tailored interventions.
A new study in mice found that concussions sustained early in life can lead to subtle brain changes that re-emerge later in life. The research highlights the importance of long-term monitoring and care following head injuries in children, as even mild symptoms may not be immediately apparent.
A new study proposes a deep learning framework that integrates multiple wavelet bases for recognizing motor imagery EEG signals in spinal cord injury patients. The model achieves high prediction accuracy and demonstrates good stability and individual convergence.
A new review from the University of Victoria suggests that psilocybin and 5-MeO-DMT may help treat concussions and traumatic brain injuries by increasing neuroplasticity and reducing inflammation. The compounds have shown promise in treating depression, anxiety, and other conditions in clinical research.
A study published in The Lancet Global Health reveals stark global inequalities in survival after emergency abdominal surgery for traumatic injuries. Patients in the world's least developed countries are more than three times likely to die within 30 days of surgery compared to those in the most developed nations.
Researchers developed an autoinjector device delivering TXA, a proven treatment for severe bleeding, with comparable effectiveness to traditional IV methods. The device can be used by paramedics and first responders to administer treatment quickly and easily, potentially saving lives in emergency situations.