Articles tagged with Traumatic Injury
A new study published in the Canadian Medical Association Journal found that older adults discharged from hospital with a new prescription for sedatives are at increased risk of falls, further need for acute hospital care, and death within 30 days. The study looked at over 1.86 million adults aged 66 years and older and found a 20% hig...
Researchers developed a pH-triggered nanocomposite that synchronizes the release of therapeutic agents, combating bacterial biofilms and oxidative stress. The platform accelerates healing and promotes tissue repair in infected wounds.
A new study by Northwestern Medicine found that patients with severe injuries from car crashes are 70% less likely to be transferred to another hospital in states with no-fault insurance laws. This is because policies guarantee reimbursement for trauma care, incentivizing hospitals to keep and treat seriously injured patients.
Researchers discovered biomarkers indicating overactivity and dysfunction in the immune system, which can lead to chronic critical illness. Identifying these markers could allow doctors to intervene earlier, leading to shorter ICU stays and improved patient outcomes.
A new study by UC San Francisco found that women with HIV are more likely to die from preventable trauma-related conditions like substance use and mental illness. The researchers say these causes are largely missing from official death records, highlighting the need for broader goals in HIV care beyond just controlling the virus.
Researchers at UC Riverside link immune signaling to disrupted brain function and cognition after concussion, finding a crucial link between TLR4 and MMP-9. Blocking these pathways may limit changes in brain circuits and improve long-term neurological outcomes.
A recent study published in JAMA found that high-dose intravenous vitamin C did not reduce mortality and persistent organ dysfunction in patients with severe burn injury. Instead, the treatment may be harmful, suggesting alternative approaches for managing burn-related complications.
Adults with lower measured glomerular filtration rates had a higher risk of all-cause mortality, kidney failure, and major adverse cardiovascular events. Lower GFR values were also associated with increased hospitalization for heart failure and acute kidney injury.
A new monitoring system, NeuroSense, tracks cerebrospinal fluid at the bedside for faster intervention in intensive care units. The system detects biomarkers of infection and flow rate, enabling early warning of complications and better treatment decisions.
A cohort study found that introducing immunity in US nursing homes was associated with lower overall staffing and staff-to-resident time. During the COVID-19 pandemic, many states adopted immunity from tort liability for harms to nursing home residents.
Scientists have created a miniature circuit that mimics the brain and spinal cord connection, showing that previously thought irreversible nerve damage can be reversed. The researchers found that blocking specific genes in mature neurons restored axon regrowth ability.
Researchers found that a high arm slot and torso tilt put the most demand on the UCL, but make mechanical changes could help pitchers reduce injury risk. The study reveals that controlled pitching delivery can minimize elbow stress and produce lower speeds.
Researchers from Zhejiang University present a comprehensive overview of stem cell-based strategies for treating traumatic brain injury. The study explores the therapeutic effects of stem cells, exosomes, and biomaterial scaffolds in promoting brain repair and functional recovery.
A national analysis found that robotic-assisted cholecystectomy remained linked to increased bile duct injury risks despite growing use. The study suggests small differences in overall complication rates between approaches.
A new study published in the British Journal of Sports Medicine found that children who received early, tailored care experienced significant improvements in recovery from concussion. The intervention combined education, physiotherapy, and psychological support, resulting in a 62.5% full recovery rate compared to 37% for those receivin...
Researchers develop an AI framework to accurately predict RNA splicing and isoform usage, addressing the need for better management strategies in patients with Hutchinson-Gilford Progeria Syndrome. The study highlights the importance of multidisciplinary coordination and prompt decision-making in this high-risk population.
A nationwide trial found that giving whole blood or its component parts to patients with severe bleeding before arriving at the hospital is equally effective. The study, which included over 1,000 patients, also showed no difference in outcomes between newer and older blood within a certain time frame.
A novel antibody, NG101, accelerates the regeneration of damaged spinal cord tissue by neutralizing a protein that blocks nerve fiber growth. This therapy enables new nerve fibers to form functional connections, allowing patients to become more independent and potentially recover arm and hand function.
Researchers tracked six NCAA Division I football players over a season and found that non-concussive head impacts correlated with changes to the gut microbiome. The study suggests that even sub-symptomatic head impacts might affect the gut microbiome, both in the immediate aftermath of injury and over a longer time course.
Scientists created hybrid macrophages that can simultaneously promote blood vessel and bone growth, potentially improving outcomes for patients with bone fractures. The discovery could lead to new cell-derived therapies that speed up recovery and improve healing.
A new study found that nearly 1,200 TBI respondents used psychedelics to treat or manage physical health conditions, with 208 participants using them to manage brain injury-related symptoms. Researchers reported a 90% self-reported symptom improvement rate.
A new study by Florida Atlantic University researchers highlights the role of urban planning in increasing pedestrian and bicyclist fatalities in the US. The study reveals that everyday destinations like grocery stores and pharmacies along busy roads significantly increase risk of serious injury or death.
A new freeze-dried blood product called Thrombosomes has shown promise in treating traumatic brain injuries by reducing swelling and bleeding. The product, derived from platelets with trehalose preservation, has been tested on mice and found to be effective in stabilizing damaged blood vessels.
Researchers at Saarland University are developing smart implants that can continuously monitor and visualize the healing process of fractures. These customized implants can dynamically adapt to the healing process by becoming stiffer or more compliant as required, promoting bone regeneration through micromechanical stimulation.
The US is not prepared for a mass disaster with multiple burn casualties, experts say. Gaps in everyday burn care for children must be addressed before it will be considered ready.
A video game developed to improve trauma triage decision making in emergency doctors has shown promising results. The game reduced under-triage rates for older patients by 49% compared to those who did not play the game, suggesting improved diagnostic abilities and adherence to guidelines.
Research shows that nine weeks of Nordic hamstring exercise training increases eccentric knee flexor strength and allows participants to control the exercise through a greater range of motion. The study found that muscle fibers can stretch to longer lengths during exercise without overstretching, reducing injury risk.
A study of young adults treated in emergency departments found that a firearm-specific risk screening tool, SaFETy score, can predict the risk of interpersonal firearm violence. The findings support the value of the SaFetY score for screening young adults for firearm risk who present to emergency departments.
A new study reveals that blocking the aryl hydrocarbon receptor (AHR) helps neurons regrow damaged axons and recover motor and sensory function. AHR acts as a key regulator that determines how neurons respond after injury, slowing down axon growth.
A new study reveals US and UK volunteer fighters in Ukraine experience high levels of mental and physical health difficulties, including PTSD, moral injury, and poor quality of life. Many struggle to access healthcare after deployment, instead relying on fellow volunteers for support.
In Ghana, Pakistan, Rwanda, and South Africa, more than half of seriously injured patients failed to reach medical care within an hour. Patients using informal means arrived quicker than those traveling by ambulance.
Researchers analyzed Oregon Medicaid case data and found that severe burns requiring hospital-level care are a growing threat in the overdose epidemic. People who smoke drugs like fentanyl and methamphetamine account for most of these cases, with butane torches posing a significant risk due to locking mechanisms.
A systematic review of 42 studies reveals a rising trend in self-injury among children and youth in high-income countries, with significant variability across countries. The findings highlight the need for effective, contextually informed prevention strategies to curb this growing concern.
A Chinese Neurosurgical Journal study developed a radiomics-based machine learning model to identify high-risk patients with traumatic brain injury who require emergency decompressive surgery. The model accurately distinguished patients who later required secondary surgery, suggesting its potential to complement clinical judgment.
A comprehensive review synthesizes the science behind vagus nerve modulation therapies, which use controlled signals to influence brain circuits and inflammation. The authors identify key mechanisms and propose next-generation treatments tailored to individual patients and conditions.
Tundra tongue is a common childhood experience where kids freeze their tongues to metal, leading to mild or no consequences. However, in 18% of cases, it results in avulsion, a piece of the tongue being torn off. Researchers found that most cases had no serious harm and suggest warming the metal with water or air to loosen the tongue.
Youth football is associated with nearly 1 in 5 traumatic brain injuries (TBIs) in children and young adults. Football players are also more likely to experience repeat TBIs, with 37% of cases occurring in athletes who participated in the sport.
The GOAL-Trauma study found significant variation in blood transfusion strategies for patients undergoing emergency abdominal surgery following trauma, with higher-resource settings using component therapy and lower-resource settings relying on whole blood transfusions.
Researchers found that veterans with prior concussions showed slower and less accurate eye movements, along with reduced performance on attention-based tasks. These subtle brain changes can be measured more than a decade after the original injury.
A study published by the American College of Surgeons found that repealing universal motorcycle helmet laws resulted in a 26% increase in average inpatient costs per motorcycle crash patient. The policy change led to more severe and expensive injuries, putting pressure on trauma centers and taxpayers.
A strategic trauma center placement was associated with reduced firearm mortality in Chicago's high-violence areas. The study highlights the importance of equitable access to trauma care, particularly in communities with limited resources.
A meta-analysis of 55 studies found a significant protective association between spirituality and hazardous alcohol and drug use. The study suggests that spiritual practices may be effective in preventing or reducing the risks associated with these substances.
Research by University of Pittsburgh surgeon-scientists reveals that EMS clinicians who treat a high number of trauma patients have improved survival rates. The study found a 10% decrease in mortality for every five additional trauma patients treated annually, with no association between years on the job and patient outcomes.
Researchers found that computerized cognitive games improved neuroplasticity in adults with chronic traumatic brain injuries, leading to better cognitive performance. The study revealed changes in white matter associated with improved processing speed, attention, and working memory.
A population-based study reveals that rotator cuff abnormalities are common after age 40 and often represent normal age-related changes. The findings challenge the clinical value of routine imaging for atraumatic shoulder pain, questioning the need for regular scans in this demographic.
A new study published in The Lancet Respiratory Medicine found that prehospital emergency intubation of high-risk trauma patients improves 30-day survival by 10.3% and could save 170 lives each year in the UK. Prehospital intubation needs to be administered by an advanced critical care team.
A new testing method uses omics markers to reveal the trajectory of recovery from trauma, enabling more-tailored care. The approach shows that organ failure and mortality can be predicted with high accuracy using biological signals found in blood.
A recent study published in Neurology suggests that individuals with traumatic brain injuries (TBI) are more likely to qualify for work disability, regardless of the severity of their injury. The study found that people with TBI had a higher likelihood of having work disability during a five-year follow-up period.
Researchers developed an advanced organoid model for human spinal cord injury and tested a promising regenerative therapy. The treatment triggered neurite growth and reduced scarring in injured organoids, offering validation for its potential to work in humans.
A study reveals that two key proteins, TSP1 and TSP2, play a central role in shaping the healing environment after injury, leading to abnormal bone growth. The findings suggest targeting these proteins may reduce harmful bone formation without interfering with healthy development.
A new software tool developed by MIT researchers can reliably and finely resolve eight distinct nerve bundles in live diffusion MRI scans, shedding light on neurodegenerative diseases like Parkinson's and Alzheimer's. The BrainStem Bundle Tool (BSBT) reveals distinct patterns of structural changes in patients with these conditions.
A clinical prediction model called the Goliat score can estimate the risk of acute complications in patients with minor and moderate traumatic brain injuries. The model, developed by researchers at UOC and IRBLleida, uses easily accessible variables to predict neurological or cardiorespiratory complications and mortality within 48 hours.
A study by Mass General Brigham found that individuals with traumatic brain injury and their caregivers consider recovery of basic communication an 'acceptable' outcome, challenging traditional assumptions about what constitutes a 'favorable' recovery. The study highlights the need for person-centered approaches to TBI outcome research.
Adverse experiences throughout life increase dementia and stroke risks, with depression as a mediating factor. Implementing life-course interventions addressing psychological trauma and mental health can reduce neurovascular disease burden.
A study published in Neurology found that taking antidepressants after a traumatic brain injury (TBI) is not associated with an increased risk of death, brain surgery, or longer hospital stays. The study included over 54,000 participants and found that antidepressant users had an 11% lower risk of needing emergency brain surgery.