Articles tagged with Traumatic Injury
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Researchers found that an astrocytic 'brake' mechanism, fueled by the neurotransmitter GABA, blocks spinal cord repair after injury. Inhibiting this pathway with the MAOB inhibitor KDS2010 enables recovery of spinal cord function in animal models.
Researchers at UVA Health System are testing a cutting-edge MRI scanner to identify brain scarring caused by blast exposures in soldiers. If successful, the technology could lead to a new imaging test to diagnose brain changes caused by repeated blasts.
Researchers create a device that prints bone grafts directly onto fractures and defects using a modified glue gun. The tool enables rapid creation of complex implants without pre-fabrication and demonstrates high structural flexibility, anti-inflammatory properties, and natural bone regrowth.
Researchers Theresa Rienmüller and Robert Winkler from Graz University of Technology have been awarded prestigious funding prizes for their innovative projects. Rienmüller is investigating electrical stimulation as a therapy for traumatic brain injury, while Winkler is developing micro-robots that could treat diseases in the human body...
The system uses magnetoelectric power-transfer technology to deliver precise electrical stimulation to organs like the heart and spinal cord. The more devices in the network, the more efficient it is, offering a less invasive alternative to traditional implantable medical devices. This technology has potential for treating conditions s...
A nationwide study analyzed data from over 2019 trauma patients treated at Level III or non-trauma centers and found that older age, public insurance, and lower designations are strong predictors of non-transfer to necessary higher-level care. The study highlights the need for strengthened trauma systems to ensure all patients receive ...
Research reveals neuroglia play active role in brain function, driving disease progression through atrophy and functional decline. Therapeutic strategies targeting neuroglial signaling may prevent damage following brain injury or protect against neurodegenerative processes.
A recent study by Mass General Brigham researchers found that adults with a history of moderate-to-severe traumatic brain injuries are at a higher risk of developing malignant brain tumors. The study evaluated data from over 75,000 people and discovered a significant association between TBI and increased tumor development.
Researchers from Kessler Foundation will share insights on spinal cord injury recovery, technological innovation, and caregiver support. The conference highlights the Foundation's leadership in rehabilitation science and commitment to advancing outcomes for individuals with SCI.
Dr. Mary Jo Pugh has made significant contributions to understanding the full range of TBI's effects, including dementia, substance use disorder, and cardiovascular disease. Her research uses big data integration to analyze patterns hidden in health data and inform preemptive interventions for veterans with TBI.
Researchers from FAU and the Sensing Institute created a detailed computer model of the mouse brain's vasculature, simulating how brain blood vessels respond to hemodynamics and vasodynamics. The model shows that transitional vessels play a critical role in regulating flow and protecting the brain during increased activity.
A recent study reveals that surgeons in the United States have a disproportionately high mortality rate compared to other highly educated professionals, including nonsurgeon physicians. The study suggests that factors such as work environment and lifestyle may contribute to this disparity.
Researchers found that taking blood thinners like warfarin does not significantly increase the risk of brain bleeding after blunt head trauma, contradicting previous assumptions. In fact, patients with poorly controlled warfarin activity had the highest bleeding risk.
A recent study by Florida Atlantic University reveals that up to 40% of hospital transfers from nursing homes can be avoided. The study identified common medical conditions linked to unnecessary hospitalizations, including feeding tube complications and urinary tract infections.
The Center for BrainHealth has received a new $1 million match gift from retired Admiral William McRaven to enhance its Optimal BrainHealth for Warfighters program. This program provides critical training for proactive brain health and introduces essential tools to measure and track change over time.
A recent Northwestern University study analyzed brain tissue from 174 donated brains, including some from former amateur football players. The researchers found no elevated levels of phosphorylated tau (p-tau) protein in the CA2 region of the hippocampus, which is often associated with CTE and normal aging.
A randomized clinical trial found that SMART training improved cognitive gains in active-duty service members with mTBI, with significant benefits seen after just one-third of the training time compared to traditional SCORE protocols. The study suggests that SMART brain training can contribute to faster return to mission readiness and ...
A randomized clinical trial found that cannabidiol (CBD) administration led to liver enzyme level elevations in 5.6% of participants and potential drug-induced liver injury in 4.9%. Hepatic enzymes returned to normal within weeks after discontinuation. Further research is needed on CBD's long-term effects and safety.
Researchers at UTA and UT Southwestern Medical School developed an adaptive spine board overlay that redistributes pressure more effectively than traditional evacuation surfaces. The device features sensor-driven pressure modulation and autonomously adjusts air-cell pressure to maintain optimal distribution for each patient.
A Rutgers Health study has discovered a way to precisely identify and target trauma sites in the body within minutes of injury. The 'traumome' is a unique protein signature that can be detected after an injury, enabling real-time diagnostics and site-specific treatments.
A new study found that slower arm movements in older adults increase the risk of falls, which can lead to hip fractures. The research team discovered that faster arm corrections can limit whole-body movement during a slip, highlighting the importance of strengthening targeted muscles.
A new study by the University of Maryland School of Medicine found that soldiers with sleep apnea are at increased risk of post-traumatic stress disorder (PTSD) and traumatic brain injury compared to those without the condition. The study also shows a higher risk of musculoskeletal injuries among service members with sleep apnea.
Research found that athletes with a BMI equal to or above 30 have increased inflammatory biomarkers, more severe concussion symptoms, and worse cognition following a concussion. The study suggests that body composition should be considered when determining the best recovery protocol after a concussion.
Research found that ADHD medication was associated with lower risks of self-harm, unintentional injury, and crime, but the magnitude of these associations decreased as prescription rates rose. The study highlights the need to regularly assess medication use in different patient populations.
A new poll reveals significant variation in older adults' preparations to age in place, with 46% having taken steps to make their home more age-friendly. However, differences persist based on health, disability, and home ownership status, highlighting opportunities for policymakers and families.
The USPSTF recommends screening for intimate partner violence in women of reproductive age. Screening for caregiver abuse is not recommended due to insufficient evidence. Abuse can result in significant injury and long-term health consequences.
Researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine aim to reduce falls and adverse drug events among older adults by using personalized approach tailored to individual genetic profiles.
A new study reveals that states with permissive firearm laws have significantly higher rates of pediatric mortality due to gun accidents. The research highlights the need for stricter regulations to prevent such tragedies and determine which laws are most effective in reducing harm.
A team of researchers has received a $3.2 million grant to upgrade the Generalized Blast Exposure Value (GBEV) tool, which assigns a numerical score to service members' blast exposure history to assess potential health outcomes.
A new study suggests that a drug used to prevent alcohol abuse can also interrupt runaway cell death and inflammation triggered by severe trauma, particularly in female mice. The findings may lead to therapies that could shorten hospital stays and improve survival rates if administered promptly after traumatic injuries.
New research reveals complex challenges Aboriginal people face when seeking support after a road traffic injury, including lack of awareness and culturally insensitive systems. The study calls for a national overhaul of compensation and return-to-work programs centered on Indigenous knowledge and cultural determinants of health.
The study analyzed 14.7 million excess US deaths from 1980 to 2023, finding that rates remained higher than pre-pandemic levels. Excess deaths during and after the pandemic were largely driven by pre-existing causes such as drug overdose, firearm injury, and cardiometabolic disease.
A study found that universal helmet laws in North Carolina resulted in higher helmet use rates (94%) compared to South Carolina (47%), leading to less severe injuries. The study also highlighted the human toll of not wearing helmets, including longer ICU stays and more ventilator support.
A new framework for assessing traumatic brain injuries (TBI) will provide more accurate diagnoses and treatments, leading to better patient outcomes. The framework incorporates clinical symptoms, biomarkers, imaging scans, and modifiers to determine the severity of injury and predict recovery.
Researchers analyzed a skeleton with a severe knee injury to uncover the complexities of social attitudes towards individuals with disabilities in medieval Europe. The study found that despite negative cultural views, some individuals with disabilities received long-term care and prominent burials.
Dr. Tarek Hanna joins UMSOM from Emory University School of Medicine with expertise in emergency and trauma imaging, clinical operations optimization, and faculty development. He will advance clinical excellence and expand radiology services across central Maryland.
A prospective clinical study found that early chest tube removal (≤3 days post-insertion) is feasible with comparable complication rates and interventions to late tube removal. The study's results support the implementation of an early removal protocol in high-volume trauma centers.
Researchers investigated the efficacy of a combination of atorvastatin and dexamethasone in treating patients with subacute subdural hematoma (sASDH). The study found significant symptom improvement and no recurrence or progression of symptoms in all five patients treated with this regimen. Non-surgical interventions for sASDH are ofte...
Researchers developed MuSICCA, a music therapy tool that uses musical stimulation to assess levels of consciousness in children with brain injuries. The study found high agreement among participants that the tool is suitable for use with children, providing guidance for caregivers and supporting clinical teams.
Researchers discovered a promising new approach to treating hemorrhagic shock, which tripled survival rates and maintained healthy organ function. Activating Protein Kinase C epsilon (PKC-ε) significantly improved early survival rates and physiological stability following severe hemorrhage.
A large US cohort study found SARS-CoV-2 infection associated with adverse postacute kidney outcomes in children and adolescents, especially those with chronic or acute kidney disease. Long-term monitoring is recommended for these patients.
Researchers at The University of Texas at San Antonio are working on a new AI tool to improve lives after brain injury. They plan to analyze data from 3,000 veterans and develop an interactive dashboard for clinicians to use, providing insights that could revolutionize treatment.
The American College of Chest Physicians' CHEST Critical Care and CHEST Pulmonary journals have been indexed in Elsevier's Scopus database. This achievement is a testament to the high-quality research published in these journals, which provide open access content in pulmonary and critical care medicine.
A qualitative study reveals that migration has a complex influence on border-region emergency medical services, leading to more injuries and deaths. Increased federal funding is needed to support the work of local EMS clinicians, who are struggling with unsustainable strain.
Researchers found that prior stress exposure impacts TBI outcomes differently in male and female rats, with males showing increased anxiety but protected social motivation, while females exhibit opposite effects on social motivation.
A new study reveals that nearly 7% of US adults have been present at the scene of a mass shooting, while over 2% have been injured during one. Younger generations are significantly more likely to have been exposed than their parents or grandparents were.
Research reveals nearly 10% of individuals with disabilities misused prescription drugs in the past year, compared to 4.4% without disabilities. Young adults and those with cognitive disabilities are particularly vulnerable to prescription drug misuse.
The Texas Tech University Health Sciences Center is conducting a randomized controlled trial to investigate the effectiveness of calcium and vasopressin in treating severely injured patients who experience significant blood loss. The study, known as CAVALIER, will enroll approximately 1,050 participants aged 18-90.
This study found that handguns were the most common firearm present in publicly targeted fatal mass shootings. Assault weapons' presence during such incidents was associated with slightly increased injuries and deaths.
Hannah Dailey, an associate professor of mechanical engineering at Lehigh University, has been recognized with the Presidential Early Career Award (PECASE) for her innovative research on fracture healing. Her virtual mechanical test can identify nonunions early in the healing process, allowing for earlier surgical intervention.
Researchers found that addressing overall mental health can contribute to maximizing recovery potential among older women recovering from hip fractures. Lower scores on the Geriatric Depression Scale (GDS) were associated with higher psychological resilience.
A significant increase in firearm-related hospital admissions was observed during the COVID-19 pandemic, with a 34% rise reported between 2020 and 2021. This surge had a disproportionate impact on vulnerable populations, including children, Medicaid patients, and Black individuals.
A new analysis of US mortality data shows men are most likely to die from traumatic brain injuries (TBI), with rates over three times higher than women. Older adults and specific racial and ethnic groups, such as American Indian or Alaska Native people, also face a higher risk of fatal TBI-related deaths.
A new study by the London School of Hygiene & Tropical Medicine estimates 64,260 traumatic injury deaths in Gaza between October 2023 and June 2024. The analysis found that approximately 3% of Gaza's population has died due to violence, with women, children, and the elderly disproportionately affected.
A clinical trial showed that an antibody blocking Nogo-A protein improves motor function in patients with incomplete spinal cord injuries. The treatment led to significant improvements in voluntary muscle activation and everyday life functional independence. Further studies are needed to confirm the findings.
A new study comparing early restrictive vs liberal oxygen for trauma patients found no significant reduction in death and/or major respiratory complications within 30 days. The study suggests that the choice of oxygen strategy may not be as critical in trauma care.
The InteReg project aims to create interactive biomaterials that instruct cells to regenerate after brain or spinal cord injuries, potentially treating MS and other neurological disorders. The project, funded by the Carl Zeiss Foundation, brings together experts in biology, chemistry, medicine, and polymer research.
Researchers developing standardized approach for ACJ reconstruction, evaluating three surgical techniques to restore stability and minimize complications. The study aims to identify most effective technique for long-term shoulder health in young athletes.
A study found that soccer heading causes structural brain abnormalities similar to those seen in CTE, affecting the frontal lobe and verbal learning. The research suggests repeated head impacts may harm brain health even without serious injury.
A new project at the University of Kansas aims to examine medical ableism and its effects on health outcomes among people with disabilities. The study will gather information directly from individuals with disabilities through the National Survey on Health and Disability.