Articles tagged with Traumatic Injury
Researchers at SwRI and Trinity University are working on a new prodrug to mitigate ischemia/reperfusion injury (IRI), which causes permanent cellular and tissue damage. The team aims to protect against IRI by targeting protein misfolding during cellular stress.
Researchers at Pitt and UPMC Children's Hospital discovered a biomarker of complicated pediatric traumatic brain injury, which may serve as dynamic indicators of post-injury recovery. The study found that children with TBI had a different epigenetic profile compared to those with orthopaedic injuries.
A new study analyzing over 5,000 homicide victim autopsies in Maryland found that a small but significant number of deaths could have been prevented with Stop the Bleed training. The program teaches bystanders how to apply pressure, pack wounds, and use tourniquets to control bleeding.
A new study found that fragmented sleep worsens symptoms of traumatic brain injury and decreases rapid-eye-movement (REM) sleep. Injured mice failed to compensate for lost REM sleep, leading to increased fatigue and decreased activity. The research highlights the critical role of uninterrupted sleep in brain injury recovery.
Victims of intimate partner violence with suicidal behavior show distinct injury patterns on medical imaging, including head, face, neck and upper limb injuries. The study aims to improve screening and intervention for vulnerable populations.
Creating a safe space free from body shaming is key to minimising female athletes' future risks of injury and protecting their health. The FAIR Consensus Statement provides practical recommendations for promoting gender-specific supportive environments in sports.
The study found significant differences in injury patterns between men and women, with men experiencing more ACL tears and women more frequent meniscal and MCL tears. These findings can help radiologists tailor imaging protocols and risk assessments to optimize patient outcomes.
Researchers found that treatment within one week of a serious head injury can reduce the risk of developing Alzheimer's disease. A study analyzing health records from over 100 million US patients showed a significant reduction in Alzheimer's risk at three and five years for those who received immediate treatment.
An international team led by Lehigh University researcher Hannah Dailey is building predictive models to understand and eventually prevent bone healing complications. The team aims to incorporate biological differences into the model, using a library of imaging data from Switzerland's AO Research Institute Davos.
Researchers at the University of Virginia Health System are exploring the role of the neurovascular unit in maintaining healthy brain function and how damage can cause chronic health conditions. The studies aim to identify new biomarkers for blast-related brain injury and develop strategies for prevention and treatment.
The European Society of Endocrinology has published a revised clinical practice guideline for the treatment of chronic hypoparathyroidism in adults, featuring a new definition and treatment algorithm. The guidelines aim to provide practical guidance for healthcare providers involved in diagnosing and managing the condition.
Researchers have summarized recent breakthroughs in theranostic nanomaterials, engineered nanoparticles that can both diagnose and treat TBI. These materials can deliver drugs precisely where damage occurs while monitoring biological changes inside the brain.
Researchers at UTA are exploring the potential of zinc to protect and regenerate muscle tissue damaged by trauma, with a focus on reducing secondary damage. The study uses a zinc-infused gel to promote muscle regeneration following blast injuries and aims to identify a safe and convenient way to apply zinc directly to muscle tissue.
The URI team developed a cost-effective, easy-to-use tabletop device to generate pressure waves mimicking blasts that cause neurodegeneration. The device helps researchers study the development and progression of neurodegenerative diseases, including TBI-related neurodegenerative disease.
A conservative dialysis approach resulted in faster and more complete kidney function recovery in patients with acute kidney injury. The study's findings suggest that this strategy could be a viable option for treating dialysis-requiring AKI, warranting further investigation.
The updated guidelines call for structured follow-up, early referral to rehabilitation, and attention to cognitive, mood, and functional changes after TBI. Health professionals are urged to screen all TBI patients for health-related social needs, such as food, housing, transportation, and financial insecurity.
A new study published in Science finds CTE shares genetic similarities with Alzheimer's disease, including DNA damage and tau protein buildup in the brain. Researchers used single-cell genome sequencing to identify somatic mutations in neurons from patients with CTE, revealing abnormal patterns of damage similar to those seen in AD.
Researchers found distinct brain features in football players, including shallower left superior frontal sulci and wider left occipitotemporal sulci, which may indicate increased risk of chronic traumatic encephalopathy (CTE). The study's findings could lead to the development of early detection tests and therapies.
Researchers from USC Neurorestoration Center and Caltech created a simple, noninvasive device using laser technology to measure brain blood flow. The tool has already been tested with humans in small proof of concept studies demonstrating its utility for assessing stroke risk and detecting brain injury.
Post-traumatic vasospasm (PTV) is a sudden narrowing of brain arteries that can lead to stroke and long-term neurological damage. Early diagnosis using tools like transcranial Doppler ultrasound and S100 protein blood tests is crucial to prevent secondary brain injury.
Researchers found that nearly all patients (94.8%) had at least one legal need, with income support being the most frequent. The Recovery Legal Care program helped secure $1.2 million in payments to patients, aiming to disrupt cycles of violence by stabilizing housing, food access, and employment.
A significant increase in pickleball-related ocular injuries has been reported among patients presenting to emergency departments. Eye protection guidelines are not currently in place, highlighting the need for standardized measures to reduce the risk of such injuries.
Researchers discovered that triggering a reversible, hibernation-like hypothermic state in male mice improved motor performance and preserved neural health following brain injury. The study found less neuroinflammation and improved neuron survival in the injured brain area.
A study of 40 women with PTSD following recent sexual assault trauma found a marked reduction in brain synchronization between the amygdala and prefrontal cortex. This disruption may be a biological signature of the disorder rather than a state-dependent marker, potentially leading to personalized treatment response.
Researchers introduced refinements to a rarely used surgical method, the reverse homodigital dorsoradial flap, for radial thumb defects. The key refinements preserved subcutaneous tissue for venous drainage and left a buffer zone at the arterial pivot point to reduce stress on blood vessels.
A cohort study found that early extracranial surgery was associated with adverse outcomes in function, cognition, and disability after moderate-severe traumatic brain injury. The study suggests that further research is needed to determine if surgical timing or other interventions can improve long-term deficits.
Researchers have made significant strides in understanding post-traumatic epilepsy (PTE), but a therapy to prevent its development remains elusive. Studies identify key barriers, including collaboration, funding, and standardization, and propose eight recommendations to advance PTE research. Potential therapies include disease modifica...
Two studies reveal that adult pedestrians suffer more severe injuries than children in motor-vehicle accidents, with adults experiencing higher mortality rates and complications. Researchers hope to identify 'hotspots' of accidents using geocoding and advocate for community changes to prevent future crashes.
Death rates from unintentional injury related to drug use increased by nearly 60% from 2018 to 2023. Middle-aged adults, particularly those aged 35-44, were found to be at higher risk of death from drug-induced accidental injuries.
A study by the American College of Surgeons found that AI enhanced evacuation efficiency, optimized routes, and prioritized patients by injury severity. AI also accelerated drug delivery, identified new treatments for injuries, and supported artificial limb selection.
A recent study published in the British Journal of Sports Medicine found that vision therapy can effectively treat concussion-related eye coordination disorders, including convergence insufficiency and accommodation insufficiency. Nearly 90% of patients in the treatment group were able to see normally after 12 weeks of therapy.
A new study examines the radiology department's experience during a mass casualty terror attack in southern Israel. Researchers found that rapid staff mobilization, versatile imaging resources management, and AI-enabled safety checks were crucial in guiding clinical decisions.
Research presented at the American Academy of Pediatrics 2025 National Conference & Exhibition found nearly half of pediatric golf cart injuries occurred in children under 12. The most common injuries were superficial lacerations and abrasions, with younger children experiencing head, face, and neck injuries.
The study, published in The BMJ, provides detailed data on traumatic injuries and medical conditions seen by healthcare workers in Gaza. It highlights the urgent need for resilient surveillance systems to inform tailored interventions.
A new study in mice found that concussions sustained early in life can lead to subtle brain changes that re-emerge later in life. The research highlights the importance of long-term monitoring and care following head injuries in children, as even mild symptoms may not be immediately apparent.
A new study proposes a deep learning framework that integrates multiple wavelet bases for recognizing motor imagery EEG signals in spinal cord injury patients. The model achieves high prediction accuracy and demonstrates good stability and individual convergence.
A new review from the University of Victoria suggests that psilocybin and 5-MeO-DMT may help treat concussions and traumatic brain injuries by increasing neuroplasticity and reducing inflammation. The compounds have shown promise in treating depression, anxiety, and other conditions in clinical research.
A study published in The Lancet Global Health reveals stark global inequalities in survival after emergency abdominal surgery for traumatic injuries. Patients in the world's least developed countries are more than three times likely to die within 30 days of surgery compared to those in the most developed nations.
Researchers developed an autoinjector device delivering TXA, a proven treatment for severe bleeding, with comparable effectiveness to traditional IV methods. The device can be used by paramedics and first responders to administer treatment quickly and easily, potentially saving lives in emergency situations.
Researchers found that an astrocytic 'brake' mechanism, fueled by the neurotransmitter GABA, blocks spinal cord repair after injury. Inhibiting this pathway with the MAOB inhibitor KDS2010 enables recovery of spinal cord function in animal models.
Researchers at UVA Health System are testing a cutting-edge MRI scanner to identify brain scarring caused by blast exposures in soldiers. If successful, the technology could lead to a new imaging test to diagnose brain changes caused by repeated blasts.
Researchers create a device that prints bone grafts directly onto fractures and defects using a modified glue gun. The tool enables rapid creation of complex implants without pre-fabrication and demonstrates high structural flexibility, anti-inflammatory properties, and natural bone regrowth.
Researchers Theresa Rienmüller and Robert Winkler from Graz University of Technology have been awarded prestigious funding prizes for their innovative projects. Rienmüller is investigating electrical stimulation as a therapy for traumatic brain injury, while Winkler is developing micro-robots that could treat diseases in the human body...
The system uses magnetoelectric power-transfer technology to deliver precise electrical stimulation to organs like the heart and spinal cord. The more devices in the network, the more efficient it is, offering a less invasive alternative to traditional implantable medical devices. This technology has potential for treating conditions s...
A nationwide study analyzed data from over 2019 trauma patients treated at Level III or non-trauma centers and found that older age, public insurance, and lower designations are strong predictors of non-transfer to necessary higher-level care. The study highlights the need for strengthened trauma systems to ensure all patients receive ...
Research reveals neuroglia play active role in brain function, driving disease progression through atrophy and functional decline. Therapeutic strategies targeting neuroglial signaling may prevent damage following brain injury or protect against neurodegenerative processes.
A recent study by Mass General Brigham researchers found that adults with a history of moderate-to-severe traumatic brain injuries are at a higher risk of developing malignant brain tumors. The study evaluated data from over 75,000 people and discovered a significant association between TBI and increased tumor development.
Researchers from Kessler Foundation will share insights on spinal cord injury recovery, technological innovation, and caregiver support. The conference highlights the Foundation's leadership in rehabilitation science and commitment to advancing outcomes for individuals with SCI.
Dr. Mary Jo Pugh has made significant contributions to understanding the full range of TBI's effects, including dementia, substance use disorder, and cardiovascular disease. Her research uses big data integration to analyze patterns hidden in health data and inform preemptive interventions for veterans with TBI.
Researchers from FAU and the Sensing Institute created a detailed computer model of the mouse brain's vasculature, simulating how brain blood vessels respond to hemodynamics and vasodynamics. The model shows that transitional vessels play a critical role in regulating flow and protecting the brain during increased activity.
A recent study reveals that surgeons in the United States have a disproportionately high mortality rate compared to other highly educated professionals, including nonsurgeon physicians. The study suggests that factors such as work environment and lifestyle may contribute to this disparity.
Researchers found that taking blood thinners like warfarin does not significantly increase the risk of brain bleeding after blunt head trauma, contradicting previous assumptions. In fact, patients with poorly controlled warfarin activity had the highest bleeding risk.
A recent study by Florida Atlantic University reveals that up to 40% of hospital transfers from nursing homes can be avoided. The study identified common medical conditions linked to unnecessary hospitalizations, including feeding tube complications and urinary tract infections.
The Center for BrainHealth has received a new $1 million match gift from retired Admiral William McRaven to enhance its Optimal BrainHealth for Warfighters program. This program provides critical training for proactive brain health and introduces essential tools to measure and track change over time.
A recent Northwestern University study analyzed brain tissue from 174 donated brains, including some from former amateur football players. The researchers found no elevated levels of phosphorylated tau (p-tau) protein in the CA2 region of the hippocampus, which is often associated with CTE and normal aging.
A randomized clinical trial found that SMART training improved cognitive gains in active-duty service members with mTBI, with significant benefits seen after just one-third of the training time compared to traditional SCORE protocols. The study suggests that SMART brain training can contribute to faster return to mission readiness and ...
A randomized clinical trial found that cannabidiol (CBD) administration led to liver enzyme level elevations in 5.6% of participants and potential drug-induced liver injury in 4.9%. Hepatic enzymes returned to normal within weeks after discontinuation. Further research is needed on CBD's long-term effects and safety.
Researchers at UTA and UT Southwestern Medical School developed an adaptive spine board overlay that redistributes pressure more effectively than traditional evacuation surfaces. The device features sensor-driven pressure modulation and autonomously adjusts air-cell pressure to maintain optimal distribution for each patient.
A Rutgers Health study has discovered a way to precisely identify and target trauma sites in the body within minutes of injury. The 'traumome' is a unique protein signature that can be detected after an injury, enabling real-time diagnostics and site-specific treatments.
A new study found that slower arm movements in older adults increase the risk of falls, which can lead to hip fractures. The research team discovered that faster arm corrections can limit whole-body movement during a slip, highlighting the importance of strengthening targeted muscles.