Articles tagged with Viremia
Public Health Alerts provide concise, data-driven information on disease outbreaks and urgent health events. The new series, launched by NEJM Evidence and CIDRAP, offers expert-reviewed reports to support public health evidence-based care.
Researchers compared HIV reservoirs between patients with early and late treatment initiation. Early treatment was associated with faster decay of virus reservoirs, indicating a more effective immune clearance mechanism. This study supports the potential for early interventions to combat HIV by enabling an eventual cure.
Researchers found large reservoirs of proviruses with mutations that help them evade detection, leading to low levels of residual viremia in individuals with HIV. Altered gene expression patterns also contributed to dampened immune responses and increased survival of infected cells.
A study of commercially insured adults with chronic noncancer pain found that state medical cannabis laws did not lead to a reduction in the use of opioid or nonopioid pain treatments. The researchers also suggested slow implementation and reluctance among healthcare leaders may have contributed to these findings.
Researchers found that Ebola virus blood levels are strong predictors of fatality, with case fatality ratios increasing with viremia levels. The study used laboratory and clinical data from 699 patients to model the association between viremia and CFR.
Scientists found that asymptomatic people can infect mosquitoes with dengue virus, representing three-quarters of all dengue infections. This challenges existing theories and highlights the potential for these individuals to contribute to the spread of the virus.
The study found that the proportion of patients on antiretroviral therapy (ART) has increased, with virologic suppression rising from 35.5% to 63%, among perinatally infected HIV patients now approaching adulthood. However, older patients are more likely to experience higher viremia and advanced immunosuppression.
A new study published in Epilepsia found that human herpesviruses (HHV)-6B and HHV-7 are associated with febrile status epilepticus (FSE) cases, accounting for one-third of FSE cases. The study suggests a possible link between these viruses and the development of epilepsy, particularly temporal lobe epilepsy.
Children exposed to nevirapine at birth who achieved viral suppression later switched to nevirapine showed better virologic suppression compared to those on protease inhibitors. This could lead to cost savings and improved adherence in low-resource settings.
A randomized controlled trial found that adding raltegravir to standard antiretroviral therapy had no effect on low-level viral load in HIV-positive individuals. The study suggests that residual viremia may be due to the release of HIV from stable reservoirs, requiring new therapeutic strategies to cure HIV infection.
Researchers found that most HIV 'blips' detected through intensive sampling were not associated with clinical significance or demographic factors. Blips were marginally linked to self-reported nonadherence, but no new drug resistance mutations were identified.