Articles tagged with High Fat Diets
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Researchers at Vanderbilt University have found a probiotic that prevents obesity by inhibiting weight gain, insulin resistance, and fatty liver in mice. The study suggests manipulating the gut microbiota could treat obesity and other chronic diseases.
A Texas A&M-led study has found that body clock dysregulation plays a key role in the development of metabolic diseases, including obesity and diabetes. The researchers discovered that overnutrition causes circadian clock dysregulation, leading to pro-inflammatory activity in adipose tissue and worsening insulin resistance.
A genome comparison reveals polar bears' rapid evolution to cope with a high-fat diet, providing insight into fatty acid metabolism and cardiovascular function. The study's findings may offer tools to modulate human physiology and protect against the ill effects of high-fat diets.
A new study published in Cell found that mice offspring of mothers consuming a high-fat diet during lactation had abnormal neuronal circuits and altered insulin signaling, leading to lifelong obesity. The study suggests that proper nutrition during critical developmental periods can impact long-term metabolic health.
A new study published in The FASEB Journal suggests that an obese father's diet may contribute to his child's risk of developing obesity, type 2 diabetes, and chronic degenerative diseases. Researchers found altered gene expression in the pancreas and fat tissue of female offspring born to obese male rats on a high-fat diet.
A recent study published in the Journal of Nutrition & Metabolism found that algal extracts from Health Enhancement Products, Inc. improved plasma cholesterol profile despite a hypercholesterolemic state induced by a high fat diet. The extracts increased 'good' cholesterol levels and decreased 'bad' cholesterol concentrations.
UC Irvine researchers found that a high-fat diet disrupts circadian rhythms, which can lead to metabolic disorders. A balanced diet normalized the rhythms, suggesting the circadian clock's adaptability.
A new mouse strain has been developed to evaluate age-promoting compounds, including UV light and cigarette smoke. These findings demonstrate that UV light and cigarette smoke exposure increase p16INK4 expression, a key marker of aging.
New research suggests that childhood exercise can improve leptin sensitivity and reduce fat deposits, potentially staving off some bad effects of maternal obesity. Exercise as early as adolescence has been shown to have a persistent effect on the satiety centers of the brain, even years later.
A high-fat diet fed to pregnant rats for 20 days resulted in preeclampsia-like syndromes and increased expression of metabotropic glutamate receptor 1 in the rat hippocampus. This finding suggests that controlling fat intake may be crucial in preventing pregnancy-induced eclampsia.
Researchers found that food contaminants, including dioxin and PCB, worsened glucose intolerance and altered estrogen pathways in female mice, but had less of an impact on male mice. The study suggests that chronic exposure to low doses of contaminants can exacerbate metabolic problems in obese individuals.
A high-fat diet in pregnant monkeys resulted in permanently changed brain cells controlling food intake, leading to increased body weight and preference for fatty foods in their offspring. This study suggests a potential long-term impact on human health.
A new study in mice finds that low testosterone worsens obesity-related brain damage, increasing the risk of type 2 diabetes and Alzheimer's disease. Obese mice with low testosterone showed more body fat, higher blood sugar levels, and poorer glucose tolerance than those with normal testosterone.
A new Ohio University study reveals that male mice fed a high-fat diet and becoming obese are more likely to father offspring with similar higher levels of body fat. The study suggests epigenetic factors may be responsible for these inherited traits.
A new study in mice found that fathers' diets before conception impact their offspring's body weight and fat content. Male offspring of paternal mice with diet-induced obesity had higher body weight and increased body fat compared to control mice.
A new study in mice found that a high-fat diet in adolescence can lead to impaired spatial memory and learning in adulthood. The researchers also found long-lasting brain changes in the mice with memory deficits, including a partial loss of leptin, a hormone that supports cognitive function.
Researchers have discovered that medications used to treat heart failure and high blood pressure can also aid in reducing obesity by preventing weight gain and increasing the production of energy-burning fat cells. The study found that these drugs helped increase brown fat cells, which burn energy to prevent weight gain.
A recent study published in the Journal of Agricultural and Food Chemistry found that green coffee bean dietary supplements do not protect against obesity-related disorders when given at higher doses. The research linked chlorogenic acid to an unhealthy build-up of fat in the liver.
Research suggests fish oils can minimize the negative effects of junk food on brain function by stimulating areas that control feeding, learning, and memory. Omega-3s may also prevent refined sugars and saturated fats from inhibiting the brain's control over food intake.
Green tea extract was shown to reduce body weight gain and insulin resistance in mice, especially when combined with polyethylene glycol. This compound prolonged gallated catechin absorption, limiting glucose uptake and improving glucose tolerance.
A new study from Massachusetts General Hospital found that feeding intestinal alkaline phosphatase (IAP) to mice on a high-fat diet prevents the development of metabolic syndrome and reduces symptoms in those already affected. IAP blocks inflammatory factors, reducing systemic inflammation.
Researchers at Brigham and Women's Hospital found that restricting food intake to a lower-fat diet before surgery reduced the imbalance in fat tissue's chemical balance, leading to improved recovery outcomes. The study suggests that minimizing trauma during surgery can have a significant impact on fat tissue's response.
A University of Illinois study found a possible link between high-fat diets and childhood brain-based conditions like ADHD and memory-dependent learning disabilities. High-fat diets triggered anxious behaviors and learning deficiencies in juvenile mice, which were reversed by methylphenidate treatment.
Researchers found that a timed high-fat diet reduces body weight and alters metabolism to utilize ingested fats for energy between meals. The study suggests scheduling food consumption can be a therapeutic tool to prevent obesity in humans.
Researchers found a specific enzyme triggers chemical reactions in female mice, leading to increased visceral fat accumulation. Estrogen suppression of the enzyme's activity may explain why postmenopausal women tend to gain belly fat.
A new Johns Hopkins study found that early diet after birth plays a significant role in determining lifetime obesity risk, rather than prenatal nutrition. Rats exposed to high-fat diets post-birth were more likely to become obese and develop metabolic disorders.
A new MIT study suggests that the protein SIRT1 plays a crucial role in protecting against metabolic disorders linked to high-fat diets, including diabetes. When given a high-fat diet, mice lacking SIRT1 developed metabolic disorders much sooner than normal mice, highlighting its potential as a safeguard against obesity-linked diseases.
A new study published in Diabetologia found that overexpressing the c-Kit receptor increases insulin production and counteracts early diabetic effects of high-fat diets. This breakthrough research provides a promising lead for developing strategies to preserve and restore function to beta cells.
Research presented at the Society for the Study of Ingestive Behavior Annual Meeting finds that high-fat diets increase active-period sleep and sleep fragmentation in rats. Poor sleep quality is associated with reduced orexin sensitivity, a key brain chemical involved in regulating sleep and wake states.
Scientists at Salk Institute found that mice who ate for 8 hours a day were healthier than those who ate freely, regardless of diet quality. Regular eating times and extended fasting may help prevent obesity, diabetes, and liver disease.
Researchers found that mice on a high-fat diet who ate in restricted eight-hour windows gained less weight, suffered less liver damage, and had lower levels of inflammation compared to those with unrestricted access. The study suggests that our body clocks may be out of sync with our eating habits, leading to metabolic issues.
A study found that high-fat diets cause differences in gut flora between thin and diabetic mice, with certain bacteria linked to diabetes development. The research suggests that modifying the gut microbiota through dietary fibers may prevent metabolic diseases like diabetes.
Researchers found that small arteries showed signs of artery damage and reduced compliance after just six weeks on a high-fat diet, while large arteries remained unaffected. This early stage of damage may be the first step in developing high blood pressure.
A study found that catch-up growth with different diets and resveratrol intervention can improve bone status. Re-feeding with normal chow showed a greater degree of improvement in mineral density than high-fat diet, while resveratrol had protective effects on bone health.
Obese mice fed green tea supplement gained weight 45% more slowly than control group, suggesting EGCG limits fat absorption and enhances fat use. Green tea did not suppress appetite and a person would need to drink ten cups daily to match study amount.
Researchers found that exercise improves arthritis symptoms in obese mice without causing weight loss. Modest improvements could have a major impact on people affected by osteoarthritis. The study's findings contradict the long-held notion that excess weight is the primary cause of the condition.
A new study published in American Journal of Physiology and Endocrinology Metabolism found that mice born to mothers on a high-fat diet before and during pregnancy have higher fat mass and smaller livers. Switching to low-fat diet reduces risk, according to researchers at Oregon Health & Science University.
Researchers found that mice without the HDAC3 enzyme experience rapid thickening of the heart muscle and heart failure on a high-fat diet. This molecular link has implications for people on Western diets and combating heart disease.
Research suggests that dietary supplementation with molasses extract can reduce body weight and fat levels in mice. After 12 weeks on a high-fat diet supplemented with 4% molasses extract, mice had lower body weight, reduced body fat, and decreased leptin levels.
A new animal study finds that a high-fat diet can cause inflammation and injury to brain cells in the hypothalamus, leading to weight gain. The research suggests that this neuronal injury may be permanent, contributing to the difficulty of achieving sustained weight loss in obese individuals.
A recent study comparing yo-yo dieting to lifelong obesity found that weight fluctuations are better for health than remaining obese. Mice on a yo-yo diet regimen lived nearly 35% longer and had improved health measures compared to those on a high-fat diet.
A new study reveals that a high-fat diet during pregnancy can decrease blood flow from the mother to the placenta and increase the risk of stillbirth. Researchers found this effect regardless of whether the mother was obese or slender, and in monkeys with hyper-insulinemia.
A new University of Illinois study published in the Journal of Physiology found that a high-fat diet during pregnancy programs a woman's baby for future diabetes. Exposure to such a diet modifies gene expression in the livers of offspring, increasing the likelihood of early insulin resistance and diabetes.
Researchers found that a short-term high-fat diet reduced tissue damage in the heart after a heart attack by up to 70%. The study suggests that 'splurges' of high fat consumption may preserve cardiac function. Further research is needed to understand why this protection wears off over time.
Researchers found that short-term high-fat diets reduced cardiac tissue damage and improved function in animal models. A sudden switch to a regular diet after the 'splurge' period offered prolonged cardioprotection.
Researchers found that social isolation combined with a high-fat diet increases levels of a brain neurotransmitter called neuropeptide Y, promoting obesity, insulin resistance, and breast cancer risk in mice. The study's findings suggest a link between human social isolation and elevated cancer risk.
A recent study in fruit flies discovered a molecular connection between obesity and heart disease, with the protein TOR playing a key role. Researchers found that manipulating TOR protected the hearts of obese flies from damage caused by high-fat diets.
Researchers found a significant link between paternal weight, diet, and an increased risk of diabetes in offspring through epigenetic changes. The study, published in Nature, showed that high-fat diets in fathers can 'program' metabolic disease in their children.
A high-fat diet causes brain cells to become insulated, rendering them unable to detect signals of fullness. The insulation also creates a further complication in that the body is unable to detect signals to increase energy use and burn off calories.
Research at Michigan State University's Breast Cancer and the Environment Research Center found that a high-fat diet during puberty can lead to inflammation in the mammary glands, promoting breast cancer growth. The study suggests that this link may be independent of obesity.
A high-fat diet is found to activate nuclear factor kappa B (NF-κB) in the prostate, leading to inflammation, oxidative stress, and proliferation. The study provides direct evidence of a link between a high-fat diet and an increased risk of benign prostatic hyperplasia, prostatitis, and prostate cancer.
Animal research suggests that a high-fat diet consumed by nursing mothers increases the risk of obesity and pre-diabetes in their offspring. In contrast, consuming a high-fat diet during pregnancy only reduces the risk of obesity when combined with postnatal breastfeeding on a low-fat diet.
A high-fat diet is associated with reduced dopamine release and reuptake in the striatum of rats. This change in brain neurochemistry affects motivation and willingness to work for food reward, mirroring effects seen in humans with obesity.
Research suggests that a pregnant mother's diet can interact with her child's genetic predispositions to affect the type or severity of birth defects, including congenital heart disease. A high-fat diet has been shown to increase the risk of this condition in mice offspring, highlighting the importance of a balanced diet during pregnancy.
Researchers found that mice lacking the FIH protein process fat differently, resulting in improved health outcomes on a high-fat diet. The lean mice exhibit enhanced insulin sensitivity and lower cholesterol levels compared to their normal littermates.
A new study by Dr. Steven Hunter found that low-carbohydrate high-fat diets do not lead to greater weight loss and increase cardiovascular disease risks. The research highlights the potential dangers of these diets for people at risk of Type 2 diabetes and obesity.
Researchers at UT Southwestern Medical Center have found that the brain plays a vital role in mediating resveratrol's anti-diabetic actions. When injected into the brain, resveratrol alleviated inflammation and activated sirtuin proteins, which may help prevent diet-induced diabetes.
A high-fat diet impairs muscle health in adolescents with pre-diabetes, leading to initial adaptations but ultimately decreased ability to use fat or glucose as fuel. The study suggests early therapeutic interventions are needed to prevent long-term functional impairment.
A controversy surrounds Sweden's promotion of low-carb high-fat (LCHF) diets, sparking concern over national public health and individual well-being. Despite scientific evidence, a group of experts was removed from the Swedish National Board of Health and Welfare due to perceived conflicts of interest.
Rats fed high-fat diets for four days showed decreased muscle oxygen use, increased heart size, and impaired maze completion. After nine days, they made more mistakes and took longer to complete tasks compared to those on a low-fat diet.