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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Turmeric extract suppresses fat tissue growth in rodent models

Researchers found that curcumin, a compound in turmeric, suppresses angiogenic activity in mice fed high-fat diets, leading to reduced fat tissue growth and lower blood cholesterol levels. The study suggests potential benefits for preventing fat tissue growth in humans.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

On a high-fat diet, protective gene variant becomes bad actor

A gene variant that protects against weight gain and insulin resistance becomes a bad actor on high-fat diets, new research suggests. Mice with the Ala12 variant show improved insulin sensitivity and better plasma lipid profiles on balanced diets but worsen these outcomes when fed a diet high in fat.

New research suggests diabetes transmitted from parents to children

A new study found that exposing fetal mice to high saturated fats can cause them and their offspring to develop type 2 diabetes. This unusual form of inheritance, known as metabolic programming, has implications for human health, particularly for children born to malnourished mothers.

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Age at puberty linked to mother's prenatal diet

A study published by The Endocrine Society found that a mother's prenatal diet high in fat can lead to an early onset of puberty in her child, increasing the risk of adulthood obesity. The research also showed alterations in sex hormones and higher body fat levels in adult offspring.

Scientists find high-fat diet disrupts body clock

A Northwestern University study found that a high-fat diet disrupts the body's internal clock, causing animals to eat during their natural rest periods. The study suggests that this disruption can lead to negative effects on metabolism and increase the risk of obesity and diabetes.

High-fat diet throws off the body's internal clock

Researchers found that high-fat diets can shift mice's activity patterns, causing them to eat more during the day and altering molecular components of the circadian clock. The study suggests that metabolic processes, like nutrient status, may influence the internal body clock.

Gene deficiency is a protective barrier to obesity

Researchers found that mice without CD38 were protected from high-fat diet-induced obesity and glucose intolerance. The study suggests that a CD38 deficiency has a protective effect against obesity, highlighting the importance of genes in regulating body weight.

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Clock gene plays role in weight gain, study finds

A study by University of Virginia researchers found that mice lacking the Nocturnin gene were resistant to weight gain on a high-fat diet and had normal liver fat levels. This discovery may lead to new treatments for inhibiting obesity and its effects on health.

Air pollution, high-fat diet cause atherosclerosis in laboratory mice

Researchers found that exposure to fine particle air pollution and a high-fat diet together contribute to the development of atherosclerosis in laboratory mice. The study suggests that even low concentrations of air pollution may accelerate the progression of atherosclerosis, particularly among those with risk factors.

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Researchers show how air pollution can cause heart disease

Researchers found that air pollution can cause atherosclerosis, the hardening of arteries, when combined with a high-fat diet. Mice exposed to polluted air developed more plaque and high blood pressure, indicating a clear cause-and-effect relationship between PM2.5 exposure and cardiovascular disease.

Rats' response to 'stop snacking' signal diminished by high fat diet

A study by Dr. Mihai Covasa and colleagues found that a high-fat diet can reduce the body's sensitivity to cholecystokinin, a hormone that helps regulate appetite, in rats. This reduced sensitivity leads to increased overconsumption of highly palatable foods high in dietary fat.

High-fat diets hammer memory, more than a waistline worry

Recent animal studies suggest that high-fat diets can impair memory and cognitive function, increasing the risk of age-related cognitive impairment. Diets rich in saturated fats and sugar may worsen cognitive losses due to stress and sleep apnea.

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High-fat diet protects newborn brain from seizure damage, study suggests

A study on infant rats suggests that high-fat diets and increased production of uncoupling protein 2 (UCP2) may protect the newborn brain from seizure-induced cell injury. The ketogenic high-fat diet is shown to work in human children to prevent or reduce seizures, sparking new research into its potential benefits.

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Genetics, not just diet, influence cholesterol levels

A study found that genetic variations can cause individuals to be more resistant to a cholesterol-lowering diet or at greater cardiovascular risk from a high-fat diet. Apolipoprotein B gene polymorphisms were associated with increased plasma total cholesterol concentrations in certain genotypes.

Female Soccer Players Perform Best On A High-Fat Diet, UB Study Finds

A new study published in UB's School of Health Related Professions found that female collegiate soccer players performed longer at a higher intensity on a diet composed of 35% fat than on lower-fat diets. The women showed no increase in weight, body fat, or blood pressure despite consuming a higher amount of fat.