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Science News for October 24, 2004


Deciphering an autism mystery

Researchers have identified a specific gene, EN2, that contributes to autism spectrum disorder (ASD). Variations in this gene may affect brain development and behavior. The study also found changes in neurotransmitter systems, including acetylcholine and serotonin, which may disrupt communication between cells.

Infection, not lack of oxygen, plays larger role in premature infant brain injury

A study published in American Journal of Obstetrics and Gynecology found that infections occur around birth are associated with an increased risk of periventricular leukomalacia (PVL), a condition causing brain tissue death. PVL is the most common form of brain injury in premature infants, resulting in cerebral palsy.

SourceJohns Hopkins Medicine·JournalAmerican Journal of Obstetrics and Gynecology·DateOct 24, 2004

Promise of stem cells amplified

Scientists have successfully used stem cells to restore movement in paralyzed rats by transplanting oligodendrocytes, a type of cell that insulates nerve signals. Additionally, researchers have delivered GDNF, a factor aiding neuron survival, to patients with Parkinson's and Huntington's diseases using genetically modified astrocytes.

Secret tobacco industry documents show Philip Morris worked to preserve ties with academic medicine

Researchers analyzed secret internal tobacco industry documents to show how Philip Morris used similar arguments to oppose divestment at Johns Hopkins University and Yale University. The company emphasized its financial contributions while suggesting investments in tobacco stock profits to maintain research funding.

SourceUniversity of California - San Francisco·JournalAcademic Medicine·DateOct 24, 2004