Articles tagged with Organ Donation
Researchers at Kanagawa University have invented a technique to store human organs for up to 10 days using the natural preservative trehalose. The method involves flushing organs with trehalose solution and storing them in silica gel, allowing for longer-term preservation without significant tissue damage.
A new study by Harvard Medical School provides a reliable method to assess current donor potential and organ procurement performance in regional and national levels. The study shows that accurate estimates of donor potential can be generated based on five key hospital variables, helping OPOs and policymakers target areas for improvement.
A study at Temple University Health System investigates whether donor bone marrow can coax recipients' immune systems to coexist without rejection of the transplanted hearts. If successful, it could lead to longer survival and reduced need for re-transplantations.
A study found that nearly one in five organ donor families would reconsider donating organs if given the chance. Factors such as prior discussion with family members, education level, and religion influenced satisfaction with donation decisions.
A study of 7,422 records found that women waited an average of 110 days to receive a liver transplant, 19 days longer than men. Minority groups also faced significantly longer wait times, with foreign nationals waiting 61 days and Asian-Americans and Hispanic-Americans waiting 138 and 107 days, respectively. The study's findings highli...
A new hybrid antibody developed at National Jewish Medical and Research Center can selectively turn off only the CD4 T cells attacking transplanted organs, allowing the immune system to fight other illnesses without suppression. Clinical trials are estimated to take approximately two years.
Researchers have developed a gene therapy technique that makes recipient's immune system tolerant of newly engrafted organs, eliminating the need for lifelong immunosuppressive drug therapy. The approach involves introducing a vector carrying the CTLA4Ig protein into an organ preservation solution before transplant surgery.
Researchers are working on a strategy to overcome hyperacute rejection by removing sugars from pig cells, targeting the GAL trigger and developing O-type blood. The goal is to produce pigs suitable for human transplantation within five years.
Researchers at UT Southwestern Medical Center have developed an oral vaccine that may prevent rejection of corneal transplants. The vaccine involves feeding processed corneal cells from donor corneas to recipients over time, training their immune system to accept donated corneas without the need for powerful immunosuppressive drugs.
A new clinical model has been developed to accurately predict survival among groups of patients with moderate to severe heart failure. The model, based on seven readily obtainable measurements, enables the efficient use of scarce donor hearts and identifies high-risk patients for enrollment in clinical trials.
A novel surgical technique developed at the UPMC has improved graft survival rates in patients receiving combined pancreas and kidney transplants. The technique protects the pancreas from injury during removal and transport, resulting in higher patient survival rates.
A Duke University Medical Center study reveals that early marrow transplants can cure nearly all cases of severe combined immune deficiency (SCID), a previously fatal disorder. The research found that treating the disease within three months of birth and using 'half-matched' parental marrow can significantly improve survival rates.
Researchers at Northwestern University have developed an implantable artificial lung that preserves lung function for 24 hours in animal models. The device is intended as a 'bridge to transplant' for patients awaiting lung transplants and as treatment for acute lung failure.