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When is dead really dead?

A new international study documents the physiology of dying and confirms that death is an irreversible process. The DePPaRT study found that cardiac activity often stops and restarts several times during the dying process, but no one regained sustained circulation or consciousness. This provides evidence to support the current standard...

SourceChildren's Hospital of Eastern Ontario Research Institute·JournalNew England Journal of Medicine·DateJan 27, 2021

To increase organs available for transplant, reassess organ procurement organizations' metrics

Researchers analyzed national organ transplant data from 2008 to 2017 and found a wide variation in organ procurement organizations' efficiency. They proposed three new metrics that would give a more accurate and equitable representation of performance, highlighting the need for improved evaluation of the organ donation system.

How opt-out organ donation could affect US waiting lists

A new study from the University of Michigan suggests that an opt-out organ donation policy could alleviate some of the burden on US waiting lists, but its impact would be marginal. The researchers found that such a policy could potentially translate to large gains in life years for thousands of patients awaiting organ transplantation.

SourceUniversity of Michigan·JournalJAMA Network Open·DateOct 2, 2019

New research offers solution to reduce organ shortage crisis

A new study in INFORMS journal Management Science proposes a two-part method combining the donor-priority rule and freeze-period to increase organ quality and quantity. The solution is estimated to boost social welfare by $235 million a year and add 18 years to patient life expectancy, while increasing organ availability by 13%.

Organ and tissue donation in patients considering MAiD: new guidance helps navigate emerging area

A new publication provides recommendations for policy makers to support organ and tissue donation in patients who choose medical assistance in dying or withdrawal of life-sustaining measures. The guidelines emphasize the importance of protecting patient autonomy, ensuring consent is informed and withdrawn at any time.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateJun 3, 2019

What does 'dead' mean?

A new special report explores the definition of death, including the controversy over brain death and its implications for organ transplantation. Leading experts discuss areas of ongoing debate, such as whether brain-dead organ donors are truly dead.

SourceThe Hastings Center·JournalHastings Center Report·DateJan 4, 2019

Organ donation in Ontario increased 57 percent since 2006 after new Canadian donation policy

A new study published in CMAJ found that organ donation in Ontario rose 57% since 2006, primarily due to the introduction of a policy allowing donation after circulatory functions cease. The study suggests that this increase has led to a positive impact on transplant activity and the overall number of donors.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateSep 25, 2017

How Spain achieved a remarkably high rate of deceased organ donation

The Spanish system has made organ donation a routine consideration when a patient dies, with professionals exploring patients' wishes regarding organ donation. The model's success lies in its coordination and organization, making it applicable to other countries with adaptations depending on the healthcare system and factors.

SourceWiley·JournalAmerican Journal of Transplantation·DateJan 9, 2017

Criteria to ID those who won't survive cardiac arrest,could be referred for organ donation

Researchers have identified three objective criteria to quickly identify patients with zero chance of survival from out-of-hospital cardiac arrest (OHCA) who can be considered for organ donation. These criteria include lack of witness emergency medical services personnel, nonshockable initial cardiac rhythm, and failure to return spont...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateSep 12, 2016

Giving HOPE: US has nearly 400 HIV-positive potential organ donors

A study published in the American Journal of Transplantation found that there are nearly 400 HIV-positive potential organ donors in the US who could provide life-saving organs for HIV-positive patients. The study estimates that these donors could reduce the waiting time for transplants, but the quality of their organs is a concern.

SourceUniversity of Pennsylvania School of Medicine·JournalAmerican Journal of Transplantation·DateMay 14, 2015

Study investigates the quality of organs from potential donors with HIV

A study explores the quality of organs from HIV-positive donors for potential transplant use in the US, finding that donor kidneys may be of reduced quality. The study suggests nearly 400 potential organ donors might be available annually, but long-term viability and hepatitis C virus infection could impact organ health.

SourceWiley·JournalAmerican Journal of Transplantation·DateMay 14, 2015

Innovative strategies needed to address the US transplant organ shortage

The US transplant organ shortage continues to grow, with thousands on waiting lists for 5 years or more. Medical leaders propose removing financial disincentives and exploring incentives like health insurance post-donation to ensure donor safety. However, there is ongoing debate about the ethics of introducing financial payments.

SourceWiley·JournalAmerican Journal of Transplantation·DateMar 31, 2015

First successful organ donation from newborn carried out in UK

A UK hospital performed the world's first successful organ donation from a newborn, involving kidney and liver cell transplants. The donor was just over 3 kg at birth and had poor brain oxygenation, leading to her death; however, her parents agreed to donate her organs for other patients in need.

SourceBMJ Group·JournalArchives of Disease in Childhood·DateJan 19, 2015

US policy that gives priority to prior organ donors who need a transplant is working

A US policy giving priority to prior organ donors has been shown to significantly reduce waiting times and improve the quality of organs received. Living donors who later need a transplant experience much shorter waits and receive higher-quality kidneys compared to those on the waiting list without donation history.

SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateNov 20, 2014

Stand-alone facility for organ retrieval is more efficient, less costly than hospital

A new study by transplant surgeons at Washington University School of Medicine found that moving organ donors from hospitals to a regional stand-alone facility significantly reduces costs and improves efficiency. The average cost of retrieving a liver dropped 37% after the change, while travel time for surgeons was reduced from 8 hours...

SourceWashU Medicine·JournalAmerican Journal of Transplantation·DateFeb 25, 2014

Social media initiative may help increase organ donations

A new social media initiative helped boost organ donor registration rates in the US, with a 21.1-fold increase on the first day of the campaign. The study suggests that social media can be an effective tool for tackling public health problems related to communication and education.

SourceWiley·JournalAmerican Journal of Transplantation·DateJun 18, 2013