Children of depressed mothers who show increased pupil dilation to sad faces are at higher risk of developing depressive symptoms and diagnoses over two years. The study suggests pupillometry could be used as a low-cost tool for pediatricians to identify children at highest risk.
Researchers used genetic sequencing to trace the 2010 measles outbreak, linking it back to two visitors who brought separate genotypes of measles to Vancouver. The D8 and H1 strains spread across the province, resulting in 82 cases of measles.
A new meta-analysis of 11,000 healthy volunteers in 394 phase I trials found that serious adverse events were rare, occurring in only 34 (0.31%) cases, and half of these were unrelated to the study drug or procedures. The majority of adverse events were mild, with nearly a quarter being judged as unrelated to the study.
As Medicaid approaches middle age, it will increasingly exercise its buying power to shape healthcare trends, including care management and population health. Despite low rates and stigma, Medicaid is a critical player in the US healthcare system, with potential for growth over the next 50 years.
A study found an inverse association between the risk of endometrial cancer in women with Lynch syndrome and later age of first menstrual cycle, increased parity, and hormonal contraceptive use. Women with the genetic condition may be counseled like the general population regarding hormonal influences on endometrial cancer risk.
A high-fat diet changes the populations of bacteria residing in the gut, altering signaling to the brain and leading to overeating. The study found that this shift can cause inflammation in brain regions responsible for feeding behavior, resulting in gut-brain miscommunication and obesity.
Researchers at Duke University Medical Center found that a nutritional supplement can improve exercise tolerance and reduce fatigue in mice by optimizing energy use in exercising muscles. The study suggests that carnitine and its enzyme CrAT work together to enhance muscle energy metabolism during exercise.
A new study published in Journal of Immunotherapy demonstrates that T cells derived from lymph nodes can be expanded and activated to attack melanoma. This innovative approach, called adoptive immunotherapy, is being tested in a human clinical trial at UH Seidman Cancer Center.
A study by Massachusetts General Hospital researchers reveals a distinctive EEG pattern associated with high-dose nitrous oxide anesthesia. This finding may help explain the drug's mechanisms and provide insights into the development of new anesthetics.
Scientists have developed a new technique to genetically engineer cells by inserting large DNA sequences at specific genomic sites. This method may be useful for producing high levels of proteins in mammalian cells.
A team from Duke University has developed a new method to measure the aging process in young adults, finding that signs of aging can appear as early as age 26. The study used 18 biological measures to determine an individual's pace of aging, with some participants aging at rates of three years per year.
Researchers exploring strategies in biology to create different mechanical properties, such as draglines and pheromonal trails, reveal principles that inform new material designs. By understanding nanoconfinement and the role of mechanics in biological systems, scientists can speed up discovery and develop innovative materials.
Researchers have discovered thousands of new peptide toxins in the venom of a single type of Queensland cone snail, opening up promising leads for new pain and cancer treatments. The study's innovative method allows for deeper analysis of venom toxins than ever before.
Scientists at UC Davis have identified endoplasmic reticulum stress as the significant driver of neuropathic pain. The discovery opens new avenues for treating chronic pain from various conditions, such as diabetes and multiple sclerosis.
Typhoon Nangka's infrared data showed cold cloud top temperatures indicating strong thunderstorms and a good circulation. The storm intensified from a tropical storm to a typhoon after NASA's Aqua satellite passed overhead on July 6.
Faith-based organisations have played critical roles in delivering education, health, and social services, particularly in hard-to-reach areas. Religious leaders provide a much-needed complement to public health messages, inspiring congregations to adopt healthy behaviours.
Researchers found key differences between people receiving hospice care in ALFs versus those cared for at home. People in ALFs were more likely to be older and female, and received help from the hospice team earlier, leading to a higher quality of life before death.
Researchers at Rice University are developing gas-releasing microbial sensors to study microbe-driven processes that regulate Earth's environment. The sensors will allow researchers to test hypotheses about how microbes control environmental processes and build model ecosystems in the lab.
Researchers found that intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events triggered by cellular senescence, providing proof-of-principal for a new treatment paradigm. The study shows that once disrupted, it takes time for the inflammatory loop to reestablish, offering hope for a safer and more effe...
Researchers used OCT to study brain vascular imaging during real-time experimental stroke, revealing high-resolution images of in vivo vascular networks and biologically initiated rescue mechanisms. This could provide guidance for clinicians treating stroke patients.
Researchers discovered that dengue virus adapts by interacting with host RNA and proteins, allowing it to bypass the immune response. This finding explains the 1994 Puerto Rico epidemic and may help predict future outbreaks.
A new study reveals that almost one in four psychiatric patients in Ontario hospitals are restrained using control interventions. This can damage therapeutic relationships and stigmatize patients, with health-care providers administering medication to manage dangerous situations.
Ticks carrying Lyme disease are increasingly found in new areas of the US, with a study suggesting southern ticks migrated northwards. Understanding these movements is crucial to identifying factors driving population shifts and reducing public health risks.
A study of 1159 males who illicitly used amphetamines found that half reported no impact on sexual functions, while the other half experienced reduced erectile rigidity, enhanced orgasmic intensity, and delayed ejaculation. Amphetamine users were also twice as likely to experience erectile dysfunction compared to matched controls.
Research published in BMJ Quality & Safety found a heightened risk of death after hospital admission at weekends in several developed countries. Patients admitted for planned surgery were more likely to die within 30 days, with a 'Friday effect' observed in Dutch hospitals.
A team of Pitt scientists has developed consensus guidelines for thyroid cancer molecular testing to help clinicians make informed decisions about diagnosing the condition. The new guidelines incorporate newly available tests that better incorporate personalized medicine into diagnosing thyroid cancer.
Children with long QT syndrome who take ADHD medications are at increased risk of experiencing heart-related problems, including syncope. Researchers call for cautious prescribing and close follow-up to mitigate this risk.
A rollator improves walking distance and time for patients with COPD, while a draisine has detrimental effects. Researchers found that unaided walking resulted in the longest distance walked by COPD patients.
A new ASU project will leverage social media to monitor and analyze conversations to determine significant dangers. The goal is to develop a logic-based framework to understand extremist mindset and motivations, supporting counter-messaging strategies.
Researchers at KU Leuven have developed a method to produce bioplastics, such as polylactic acid (PLA), more efficiently and with less waste. This breakthrough could lead to cheaper and more sustainable production of biodegradable plastics.
Researchers developed a lightweight system to produce therapeutic nitric oxide from the air using an electric spark, overcoming size and cost limitations of existing equipment. The device shows promise for treating conditions like pulmonary hypertension, chronic lung diseases, and certain types of heart failure.
A new RAND Corporation study found that adolescents who saw medical marijuana ads were twice as likely to use the substance or report plans to use it in the future. The study suggests a need to revise prevention programming for youth as legalization and visibility surrounding marijuana change.
Researchers found that an extra set of guanines in our DNA may function like a spare tire to repair damage and prevent cancer. This 'factory-installed safety feature' could be a key to understanding why some people don't develop cancer despite high levels of oxidative stress
A new study reveals how synchronized gene activation is achieved in developing neurons through a TTP/miR-9 regulatory pair, which limits messenger destabilization and ensures coordinated accumulation of neuronal proteins.
Ezrin regulates osteosarcoma's spread by acting as an air traffic controller, coordinating multiple functions within cancer cells and allowing them to survive stress conditions. Researchers have developed molecules that block ezrin's function, preventing osteosarcoma spread in mouse models.
The updated ecoprofile data assesses energy, water, and resource usage, as well as air and water emissions and solid waste. Ingeo biopolymers replace petroleum-derived materials in various products, offering positive lifecycle benefits.
A study examines the effect of DEHHP on PVC flexibility, revealing molecular-level interaction between hydrogen bonds and improving polymer-solvent interactions. The research shows that temperature and concentration affect the strength of these interactions.
New research reconstructs beetle family tree, showing diversification over nearly 300 million years. The success of beetles attributed to low extinction rates and interactions with plants, fungi, and microorganisms.
Research suggests differences in oil-secreting glands and dermis thickness contribute to wrinkle formation. The study, published in Clinical Anatomy, found shallower wrinkles on the forehead compared to the outer eye area.
Biologists from Penn University analyzed genetic data to track blacklegged tick migrations. The study reveals that ticks moved into new areas through short-distance local moves, shedding light on patterns of disease spread and controlling strategies.
Researchers at UCSF found that frequent premature ventricular contractions (PVCs) are associated with heart failure incidents and increased mortality. PVCs can be prevented through medical or ablation therapy, suggesting they may be a modifiable risk factor for congestive heart failure and death.
A recent Arctic tundra study found that climate warming is driving dramatic changes in the region's vegetation, with shrubs growing more in warmer temperatures. This increase in shrub growth can lead to more warming in tundra ecosystems and globally.
The project aims to improve food environments and increase physical activity in southwest Atlanta's target neighborhoods. Over three years, it will work to increase healthy food access for at least 75% of the communities.
A newly discovered human protein called intelectin has the ability to selectively identify and distinguish between human cells and those of disease-causing microbes. This discovery could lead to the development of new antibiotics and strategies to combat infectious diseases.
Typhoon Chan-Hom strengthened over three days, peaking as a Category 4 typhoon with maximum sustained winds nearing 130 knots. The storm is forecast to pass between Ishigakjima and Kadena islands on July 9 before making landfall in eastern China.
Researchers discovered a link between autoimmune diseases and Long QT syndrome, a potentially life-threatening heart condition. Screening and counseling are now recommended for patients with certain medications or abnormal electrolytes.
A new study reveals that older patients with traumatic spinal cord injuries are less likely to receive surgery and experience longer wait times for treatment. The delay in diagnosis and treatment may be due to age-related biases or delayed recognition of less severe injuries.
Researchers found an enzyme called LSD1 turns off genes required to maintain cancer stem cell properties in glioblastoma. Drugs modifying LSD1 levels could provide a new approach to treating the disease.
A new study published in Nature Climate Change suggests that climate change will not lead to widespread interbreeding among closely related species. Only about 6 percent of species with non-overlapping ranges are likely to come into contact by the end of this century.
A recent study found that approximately 1 in 6 aging individuals would be reclassified as having 'at goal' blood pressure under the new guidelines, despite frequent use of antihypertensive medications. The study suggests that less stringent blood pressure goals may increase the risk for heart attacks and strokes among older adults.
Researchers at Cedars-Sinai Medical Center tested two methods to preserve cognition in laboratory mice with Alzheimer's disease. Immune cells from bone marrow and a drug for multiple sclerosis were found to travel into the brain, resisting abnormalities associated with the condition. The study showed measurable benefits in mice.
A new study reveals that smooth muscle cells play a more complex role in the formation and stability of atherosclerotic plaques than previously thought. The researchers found that 82% of smooth muscle cells within advanced lesions cannot be identified using traditional methods, leading to confusion about cell identity.
A recent study from Michigan State University found that perennial biofuel crops use a comparable amount of water as traditional corn crops in the Midwest. This discovery has significant implications for cellulosic biofuel production and understanding the impact of climate change on water balances.
Rice University's HERC will explore new areas of education research in HISD, linking data with other sectors like early childcare and the workforce. The funding supports HERC's connection between research and policy/practice to improve educational services.
A previously unknown leafhopper species has been found in the New Jersey Pine Barrens, threatening a listed threatened pinebarren smokegrass species. This discovery highlights the impact of climate change and human activities on ecosystems.
A blood-borne molecule called beta-2 microglobulin increases with age and blocks brain cell regeneration, leading to cognitive decline. Administering the molecule to young mice reverses this effect, suggesting a potential therapeutic target for age-related cognitive diseases.
Researchers found that coronary artery calcification scans can accurately predict all-cause mortality up to 15 years in asymptomatic patients. The study's findings suggest that CAC scanning could help physicians identify patients at risk for early death and advise them to adopt healthier lifestyles.
A new study found that over 750 popular music songs reference weather, with a range of emotions conveyed through multiple weather types in some songs. Popular artists like Bob Dylan, John Lennon, and Paul McCartney have written or sung about weather-related topics.
A study by Leuphana University and George Mason University found that preschoolers with a good understanding of their emotions experienced fewer attention problems. The research suggests that emotion knowledge is a key factor in the development of attention skills, alongside executive functions.
A new investigational vaccine designed to protect against West Nile Virus infection is being tested in a Phase 1 clinical trial. The vaccine was developed with a novel, hydrogen peroxide-based process that renders the virus inactive while maintaining key immune-system triggering surface structures.