Articles tagged with Cancer Patients
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Researchers at the National Cancer Institute found that children and young adults with sarcoma are at increased risk of developing thromboembolic events (blood clots) in their veins. The study found that patients whose cancer had spread beyond the original site were more likely to develop a blood clot.
A randomized controlled trial of high-risk gastric cancer patients showed no significant difference in survival between two treatment groups. The five-year survival rate was around 50%, higher than previous studies, suggesting that the quality of surgery and potential toxicity of postoperative chemotherapy may be factors.
A novel cell culture technique could lead to the discovery of new drugs for preventing DCIS recurrence or progression. Breast cancer cells expressing a shortened form of the HER2 gene can be treated with lapatinib, but are resistant to trastuzumab.
Researchers found that cetuximab improved overall survival by 23% and reduced disease progression risk by 32%. The drug targets the EGFR receptor on cancer cells, preventing cell growth and triggering an immune response.
Researchers found that Hodgkin's disease survivors with higher chromosomal aberrations are two-and-a-half times more likely to develop another type of cancer. Chromosomal breaks, particularly those on one chromosome arm, may serve as a biomarker for predicting second primary tumor risk.
Researchers found that early age at first birth protects against ERPR-positive breast cancer, but not receptor-negative. Breastfeeding was protective for both subtypes, regardless of when a woman gave birth. Women who delay childbearing may benefit from breastfeeding to reduce their risk.
The American Association for Cancer Research (AACR) and Susan G. Komen for the Cure have launched a partnership to address cancer disparities and promote prevention. The $2M pledge will support educational outreach, public forums, and research initiatives.
Researchers at Virginia Commonwealth University Massey Cancer Center have induced cell death in leukemia cells using a combination of bortezomib and romidepsin or belinostat. The findings suggest potentiated lethality and additive effects in human CLL cells.
Research found that individuals with melanoma diagnosed by a dermatologist tend to have thinner tumors, leading to improved five-year survival rates. The study analyzed data from Medicare and cancer databases, comparing outcomes between dermatologist- and non-dermatologist-diagnosed patients.
A phase III trial of darbepoetin alfa found that the drug did not reduce blood transfusion risk in non-chemotherapy patients, but increased overall patient mortality. Patients with certain types of cancer saw better survival outcomes when treated with the drug.
Researchers have developed tests that diagnose, predict or monitor cancer risks without invasive tissue sampling, benefiting underserved populations. DNA methylation mapping from exhaled breath can identify early-stage lung cancer, while an oral rinse test detects head and neck squamous cell carcinoma
Researchers found that approximately 97% of patients who received imatinib after surgery did not experience cancer recurrence, compared to 83% of those who received placebo. Gleevec was well-tolerated by most patients and showed significant benefits in decreasing cancer recurrence.
Researchers found that patients who received Gleevec after surgery were significantly less likely to have cancer recurrence compared to those who didn't receive it. The study showed a 97% survival rate for patients on Gleevec, with only mild side effects reported.
The American Association for Cancer Research will present the AACR Distinguished Service Award and the AACR Public Service Award to Dr. Andrew C. von Eschenbach, Dr. Harold P. Freeman, and Dr. LaSalle D. Leffall, Jr., recognizing their outstanding contributions to leadership, education, and advocacy in cancer research. The awards will ...
A new study examines partners of cancer survivors who underwent blood and marrow transplant, finding equal levels of mental health impairment, but with differing treatment outcomes and social support
The American Association for Cancer Research (AACR) is honoring world-class cancer researchers who have made significant contributions to the fight against cancer. The winners of the 2007 AACR research achievement awards include Dr. Janet S. Butel, Dr. Harold P. Freeman, and Dr. Alexander Varshavsky.
The Wesley Research Institute Tissue Bank has collected its first batches of cancer tissue, providing a valuable resource for researchers to study the cause, progression, and potential treatment of cancer. This step forward in cancer research is expected to lead to significant advancements in diagnosis and treatment.
Testicular cancer survivors have a higher risk of dying from noncancer causes, including infections and circulatory diseases. Chemotherapy treatment in the 1970s also increases this risk. Researchers highlight the need for additional long-term follow-up studies to better understand secondary complications.
A new study reveals that recent declines in breast cancer mortality rates have been most significant among women with estrogen receptor (ER)-positive tumors and women younger than 70. These groups experienced a 38% decline in mortality from breast cancer, compared to a 19% decline for ER-negative tumors.
Donald Metcalf is recognized for his groundbreaking research on blood cell formation and colony-stimulating factors, which revolutionized cancer treatment. His work led to the development of therapies accelerating hematopoietic regeneration in patients, reducing infection risk and shortening hospital stays.
A study found that only one quarter of general surgeons refer eligible patients for breast reconstruction consultations, resulting in low rates of the procedure in the US. Factors such as surgeon attitudes and patient knowledge play a significant role in referral practices.
Researchers found that immune response to SOX2 protein protects against myeloma development in patients with monoclonal gammopathy of undetermined significance. This discovery suggests targeting cancer stem cells may be key to preventing or treating myeloma.
A new light-based probe built by researchers at Duke University has successfully detected the earliest signs of cancer in cells lining internal organs. The device uses changes in laser light scattering to identify pre-cancerous conditions, offering a promising alternative for early diagnosis and treatment.
A new study by the University of Wisconsin-Madison's Center of Excellence in Cancer Communications Research found that accessing high-quality health information online can improve breast cancer patients' opinions about their doctors. The study also discovered a positive correlation between using online services and patient satisfaction...
Researchers at the University of Alberta found that advanced cancer patients experience unique and persistent taste and smell abnormalities, leading to malnutrition and poor quality of life. A personalized diet tailored to an individual's needs may improve their quality of life.
Scientists have found a way to activate EBV inside tumors, allowing them to identify patients whose infection can be manipulated to destroy their tumors. The technique uses two agents already on the market to light up tumor viruses, offering a novel approach to treating cancers associated with Epstein-Barr.
Patients with RA have double the risk of death from cancer compared to the general population. However, RA patients do not have an increased risk of developing cancer. A long-term study found a 40% increase in mortality among those who suffered both RA and cancer.
Researchers found that those with three or more cancer biomarkers who used aspirin had a 30% risk of esophageal cancer after 10 years, compared to 79% without NSAIDs. The study identified four genetic abnormalities predictive of esophageal cancer progression.
A study found that childhood cancer survivors are at a higher risk of developing secondary sarcomas, such as soft tissue sarcomas and osteosarcoma, with an average latency period of 11 years after primary diagnosis. Radiation therapy is associated with this increased risk.
Researchers found that telomere length shortens with every successive generation in families with Li-Fraumeni syndrome, resulting in more severe cancers at an earlier age. This discovery could represent the first biological marker for clinical monitoring in these families.
A phase III clinical trial found that the first antisense drug, oblimersen, improved response rates in CLL patients who remained sensitive to chemotherapy drug fludarabine. The study showed a four-fold increase in 'CR/nPR' in these patients compared to those no longer responding to fludarabine.
Researchers at Dana-Farber Cancer Institute and Broad Institute develop a practical method for screening tumors for cancer-related gene abnormalities, paving the way for personalized medicine. The technique uses high-throughput genotyping to detect important mutations in oncogenes with high accuracy and sensitivity.
People with advanced cancer reported better quality of life when receiving spiritual support from religious communities and medical service providers. The study suggests that making a 'spiritual history' routine part of patient care can improve patients' well-being at the end of life.
A new study found that hairy cell leukemia survivors have an increased risk of developing certain cancers, including Hodgkin lymphoma and thyroid cancer. Meanwhile, a new test may be able to identify patients with a specific type of gene mutation that indicates an inherited form of colorectal cancer or potential response to certain drugs.
Scientists have linked telomere loss to both cancer and aging by visualizing chromosomes of cells from patients with Werner Syndrome. Rebuilding structures called telomeres significantly blocks genetic damage seen in cells of patients with Werner Syndrome.
Researchers at UT Southwestern Medical Center have found a new biomarker test that can predict the recurrence of bladder cancer in patients. The test uses molecular biomarkers to identify patients who are more likely to experience cancer recurrence, allowing for personalized treatment options.
Researchers investigate fatigue in various populations, finding distinct definitions for tiredness, fatigue, and exhaustion. The study aims to prevent progression from tiredness to exhaustion, emphasizing the importance of recognizing changes consistent with fatigue and exhaustion.
Researchers at Georgetown University Medical Center found that young cancer survivors are at risk of developing unhealthy behaviors, including smoking, lack of exercise, and inadequate sun protection. The study suggests that these behaviors can increase the risk of cancer recurrence and chronic disease in adulthood.
Researchers at University of Texas M. D. Anderson Cancer Center found that aspirin significantly improves survival rates among cancer patients with low platelet counts who experience heart attacks, even when taking anticoagulants. Aspirin also showed benefits for patients with normal platelet counts.
A new surgical technique, 'beavertail' surgery, has given back the ability to swallow to patients with tongue cancer. The procedure involves modifying an existing technique by adding a 'jellyroll' of fat and connective tissue to replace diseased tongue tissue.
A study found that chemotherapy with gemcitabine significantly delayed cancer recurrence in patients following pancreatic cancer surgery. The estimated median disease-free survival was 13.4 months for the gemcitabine group compared to 6.9 months for those without chemotherapy.
Researchers found that a drug blocking nitric oxide synthesis significantly reduced tumor blood volume in patients, providing early clinical evidence of its anti-vascular activity. The study's results suggest potential for the use of this agent as a novel vascular targeting agent in cancer treatment.
A new study by Herman Suit and colleagues reveals great heterogeneity in radiation-associated cancer risk between species, strains, and organs. The researchers conclude that dose reductions to less than 2 Gy can lead to substantial gains in reducing secondary cancer risks.
A survey of 54 cancer centers found few organizations have standardized prescribing practices for oral chemotherapy, with variations in prescription generation and required information. The study highlights the importance of forging a consensus on standardized safeguards and practices for prescribing and monitoring oral chemotherapies.
A new study published in CANCER journal reveals that patients with pancreatic cancer are more likely to receive radiotherapy if the treating hospital has it available, while rectal cancer patients have equal access regardless of hospital radiation capacity. The findings suggest adjuvant radiotherapy for pancreatic cancer may be over-ut...
Researchers at MGH Cancer Center identified a novel gene mutation associated with Wilms tumor in 30% of cases. The mutated gene, WTX, is located on the sex-determining X chromosome and plays a key role in embryonic kidney development.
A new study by the University of Wisconsin-Madison found that breast cancer patients who pray in online support groups experience lower levels of negative emotions and higher self-efficacy. The study analyzed message transcripts from 97 patients and discovered a positive correlation between prayer and improved mental well-being.
A new study estimates the patient time costs associated with cancer care, finding that hospitalizations were the largest component of patient time costs in both initial year after diagnosis and last year of life. The estimated net patient time costs ranged from $271 for melanoma to $7,799 for gastric cancer.
A cost-utility analysis found that long-course palliative radiotherapy improved survival and quality of life in late-stage non-small-cell lung cancer patients. The study showed a $5,326 difference in lifetime societal costs between the two treatment regimens.
A University of Washington-led team has identified a mutated form of the Palladin gene as the cause of familial pancreatic cancer. The discovery reveals that this genetic abnormality causes cancer cells to move abnormally, invading surrounding healthy tissue.
Researchers at M.D. Anderson Cancer Center report clinical activity of MK-0457 against T315I BCR-ABL mutation in CML and ALL, and JAK-2 mutation in myeloproliferative disorders. The drug shows minimal side effects and has potential to benefit patients with these rare and aggressive cancers.
A new bile duct stent called Dua Anti-Reflux Valve has been shown to improve the quality of life for patients with pancreatic and bile duct cancers. The stent's anti-reflux valve reduces backflow of intestinal contents, resulting in fewer repeat procedures and better outcomes.
A study presented at the American Society of Hematology Meeting shows Revlimid can provide long-term durable results in MDS patients, helping them achieve blood transfusion independence. After over two years of follow-up, two-thirds of patients were completely freed from the need for blood transfusions.
Researchers at Mayo Clinic Cancer Center found that tipifarnib can stall or reverse disease progression for patients with relapsed aggressive non-Hodgkin lymphoma. The study showed a partial response in 18% of patients and stable disease in 21%, while also improving quality of life.
A study found that close to half of smokers who underwent early-stage lung cancer surgery resumed smoking within 12 months, with 60% resuming in the first two months. Patients' self-efficacy and perceived pleasure from smoking drove their relapse rates.
A novel regimen of three chemotherapy drugs resulted in a significant clinical response in patients with previously untreated chronic lymphocytic leukemia (CLL). The treatment showed promise for high-risk patients, with no age restrictions, and minimal side effects.
A study from Michigan Medicine found that over half of breast cancer patients who sought a second opinion received a change in their recommended treatment plan. Changes were often made based on reinterpreted imaging results or differing diagnoses, leading to new treatment recommendations.
Researchers found significant regions of the brain associated with memory, analysis, and cognitive functions were smaller in breast cancer patients who received chemotherapy compared to those who did not. However, these structural changes were not sustained after three years.
Researchers found that a radical prostatectomy can be a viable option for select octogenarian patients with localized prostate cancer. The 10-year survival rate was similar to that observed in healthy patients 60-79 years old undergoing a radical prostatectomy.
A new study found that hematopoietic stem cell transplant (HSCT) recipients face a significant long-term risk of developing a second cancer, with the risk almost doubling within 10 years. The study also identified specific risk factors, including age at transplant and donor cell type.