Articles tagged with Cancer Patients
A new study by Duke University Comprehensive Cancer Center researchers shows that E Tables may be useful in collecting patient history data and conducting clinical research. Patients report being satisfied with the tablets and finding them comparable to paper forms in terms of data quality.
A large Phase III study found that shark cartilage extract AE-941 has no benefit when combined with chemotherapy and radiation for patients with advanced non-small cell lung cancer. The study did not meet its primary endpoint: survival, and the researchers cast major skepticism on the efficacy of shark cartilage products.
Patients with stage four cancer have less quality sleep, which is linked to functional performance, mental health, and pain status. Poor sleep quality can be a critical factor in cancer treatment, highlighting the need for effective symptom management.
Researchers have identified C-reactive protein (CRP) as a strong indicator of survival for men with advanced prostate cancer. The study found that higher levels of CRP are associated with shorter survival and lower response to chemotherapy.
The partnership aims to create programs and provide grants that support tangible improvements in access to and delivery of cancer care, particularly for disparities and clinical trials. The initiative also focuses on solutions to the projected shortfalls of the oncology workforce and addresses the unique needs of cancer survivors.
A blood test detecting tumor-related proteins may help monitor treatment effectiveness and predict cancer recurrence. Patients with low protein levels were more likely to remain in remission, while those with high increases were at higher risk of cancer return.
A new study found that only 9% of breast cancer specialists adhere to guidelines for follow-up care, with varying frequencies of mammograms and discharge times. The research highlights the need for improved coordination between specialists and general practitioners to provide better patient care.
A study of 666 head and neck cancer patients found that 38.1% discontinued work due to cancer and treatment, with fatigue being the leading factor. The study highlights the need for interventions to minimize disability after treatment and provide more information about employment to patients.
A new study found that cancer survivors are more likely to attend support groups compared to people with other chronic conditions. However, few survivors receive referrals to such programs from their physicians. The study also revealed that predictors of use include female gender, Caucasian race, and symptoms of depression or anxiety.
Reolysin works synergistically with standard anti-cancer drugs, providing stronger responses than either agent alone. It also primes patients' immune systems against their particular cancer, leading to additional cancer cell killing and long-term remissions.
A report by European Society for Medical Oncology reveals stark inequalities in access to cancer treatment globally. Key findings include that Austria, France, and the US have high uptake of new cancer drugs, while countries like New Zealand, Poland, and South Africa have low uptake.
Two studies by Dartmouth Medical School researchers reveal that US movies deliver billions of smoking impressions to American teens, with youth-rated movies delivering 61% of the total images. The studies also found that high-impact movies, mostly rated PG-13, deliver over 100 million smoking impressions each.
A recent study found that MR imaging can predict prostate cancer recurrence in patients with extracapsular extension. The study, which analyzed 74 men with biopsy-proven prostate cancer, identified features on imaging that indicated a higher risk of metastasis.
Researchers at the University of Illinois Chicago are studying fatigue in cancer patients undergoing stem cell transplants using ecological momentary assessment. Patients use a wearable device to record their fatigue intensity, providing an instant measurement of symptoms that can interfere with daily functioning.
Research grants aim to reduce suffering for seriously ill patients and their caregivers, with studies focusing on communication, treatment advances, and caregiving support. The initiative supports clinician investigators conducting patient-oriented research in palliative care.
A recent study by researchers at the University of Pennsylvania School of Medicine found no evidence linking psychotherapy to increased survival rates among cancer patients. Despite previous studies suggesting a potential benefit, the authors conclude that psychotherapy can improve quality of life without extending lifespan.
Using erythropoiesis-stimulating agents (ESAs) to treat non-chemotherapy-related anemia in cancer patients may increase the risk of death, thromboembolic events, and potentially even cancer growth. Researchers recommend a cautious approach until further scientific data is available.
Patients with metastatic colorectal cancer treated with EGFR-targeted monoclonal antibodies experience significant magnesium loss, affecting up to 97% of patients. The study suggests that identifying high-risk patients through patient characteristics could aid early intervention to prevent severe hypomagnesaemia.
A new stent has been shown to relieve GI upper cancer distress by incorporating an anti-reflux valve, which reduces backflow of intestinal contents into the bile duct. The study found that patients with the Dua stent had a longer median of 145 days without complications compared to those with standard stents.
Researchers at the National Cancer Institute found that children and young adults with sarcoma are at increased risk of developing thromboembolic events (blood clots) in their veins. The study found that patients whose cancer had spread beyond the original site were more likely to develop a blood clot.
A randomized controlled trial of high-risk gastric cancer patients showed no significant difference in survival between two treatment groups. The five-year survival rate was around 50%, higher than previous studies, suggesting that the quality of surgery and potential toxicity of postoperative chemotherapy may be factors.
A novel cell culture technique could lead to the discovery of new drugs for preventing DCIS recurrence or progression. Breast cancer cells expressing a shortened form of the HER2 gene can be treated with lapatinib, but are resistant to trastuzumab.
Researchers found that cetuximab improved overall survival by 23% and reduced disease progression risk by 32%. The drug targets the EGFR receptor on cancer cells, preventing cell growth and triggering an immune response.
Researchers found that Hodgkin's disease survivors with higher chromosomal aberrations are two-and-a-half times more likely to develop another type of cancer. Chromosomal breaks, particularly those on one chromosome arm, may serve as a biomarker for predicting second primary tumor risk.
Researchers found that early age at first birth protects against ERPR-positive breast cancer, but not receptor-negative. Breastfeeding was protective for both subtypes, regardless of when a woman gave birth. Women who delay childbearing may benefit from breastfeeding to reduce their risk.
The American Association for Cancer Research (AACR) and Susan G. Komen for the Cure have launched a partnership to address cancer disparities and promote prevention. The $2M pledge will support educational outreach, public forums, and research initiatives.
Researchers at Virginia Commonwealth University Massey Cancer Center have induced cell death in leukemia cells using a combination of bortezomib and romidepsin or belinostat. The findings suggest potentiated lethality and additive effects in human CLL cells.
Research found that individuals with melanoma diagnosed by a dermatologist tend to have thinner tumors, leading to improved five-year survival rates. The study analyzed data from Medicare and cancer databases, comparing outcomes between dermatologist- and non-dermatologist-diagnosed patients.
A phase III trial of darbepoetin alfa found that the drug did not reduce blood transfusion risk in non-chemotherapy patients, but increased overall patient mortality. Patients with certain types of cancer saw better survival outcomes when treated with the drug.
Researchers have developed tests that diagnose, predict or monitor cancer risks without invasive tissue sampling, benefiting underserved populations. DNA methylation mapping from exhaled breath can identify early-stage lung cancer, while an oral rinse test detects head and neck squamous cell carcinoma
Researchers found that approximately 97% of patients who received imatinib after surgery did not experience cancer recurrence, compared to 83% of those who received placebo. Gleevec was well-tolerated by most patients and showed significant benefits in decreasing cancer recurrence.
Researchers found that patients who received Gleevec after surgery were significantly less likely to have cancer recurrence compared to those who didn't receive it. The study showed a 97% survival rate for patients on Gleevec, with only mild side effects reported.
The American Association for Cancer Research will present the AACR Distinguished Service Award and the AACR Public Service Award to Dr. Andrew C. von Eschenbach, Dr. Harold P. Freeman, and Dr. LaSalle D. Leffall, Jr., recognizing their outstanding contributions to leadership, education, and advocacy in cancer research. The awards will ...
A new study examines partners of cancer survivors who underwent blood and marrow transplant, finding equal levels of mental health impairment, but with differing treatment outcomes and social support
The American Association for Cancer Research (AACR) is honoring world-class cancer researchers who have made significant contributions to the fight against cancer. The winners of the 2007 AACR research achievement awards include Dr. Janet S. Butel, Dr. Harold P. Freeman, and Dr. Alexander Varshavsky.
The Wesley Research Institute Tissue Bank has collected its first batches of cancer tissue, providing a valuable resource for researchers to study the cause, progression, and potential treatment of cancer. This step forward in cancer research is expected to lead to significant advancements in diagnosis and treatment.
Testicular cancer survivors have a higher risk of dying from noncancer causes, including infections and circulatory diseases. Chemotherapy treatment in the 1970s also increases this risk. Researchers highlight the need for additional long-term follow-up studies to better understand secondary complications.
A new study reveals that recent declines in breast cancer mortality rates have been most significant among women with estrogen receptor (ER)-positive tumors and women younger than 70. These groups experienced a 38% decline in mortality from breast cancer, compared to a 19% decline for ER-negative tumors.
Donald Metcalf is recognized for his groundbreaking research on blood cell formation and colony-stimulating factors, which revolutionized cancer treatment. His work led to the development of therapies accelerating hematopoietic regeneration in patients, reducing infection risk and shortening hospital stays.
A study found that only one quarter of general surgeons refer eligible patients for breast reconstruction consultations, resulting in low rates of the procedure in the US. Factors such as surgeon attitudes and patient knowledge play a significant role in referral practices.
Researchers found that immune response to SOX2 protein protects against myeloma development in patients with monoclonal gammopathy of undetermined significance. This discovery suggests targeting cancer stem cells may be key to preventing or treating myeloma.
A new light-based probe built by researchers at Duke University has successfully detected the earliest signs of cancer in cells lining internal organs. The device uses changes in laser light scattering to identify pre-cancerous conditions, offering a promising alternative for early diagnosis and treatment.
A new study by the University of Wisconsin-Madison's Center of Excellence in Cancer Communications Research found that accessing high-quality health information online can improve breast cancer patients' opinions about their doctors. The study also discovered a positive correlation between using online services and patient satisfaction...
Researchers at the University of Alberta found that advanced cancer patients experience unique and persistent taste and smell abnormalities, leading to malnutrition and poor quality of life. A personalized diet tailored to an individual's needs may improve their quality of life.
Scientists have found a way to activate EBV inside tumors, allowing them to identify patients whose infection can be manipulated to destroy their tumors. The technique uses two agents already on the market to light up tumor viruses, offering a novel approach to treating cancers associated with Epstein-Barr.
Patients with RA have double the risk of death from cancer compared to the general population. However, RA patients do not have an increased risk of developing cancer. A long-term study found a 40% increase in mortality among those who suffered both RA and cancer.
Researchers found that those with three or more cancer biomarkers who used aspirin had a 30% risk of esophageal cancer after 10 years, compared to 79% without NSAIDs. The study identified four genetic abnormalities predictive of esophageal cancer progression.
A study found that childhood cancer survivors are at a higher risk of developing secondary sarcomas, such as soft tissue sarcomas and osteosarcoma, with an average latency period of 11 years after primary diagnosis. Radiation therapy is associated with this increased risk.
Researchers found that telomere length shortens with every successive generation in families with Li-Fraumeni syndrome, resulting in more severe cancers at an earlier age. This discovery could represent the first biological marker for clinical monitoring in these families.
A phase III clinical trial found that the first antisense drug, oblimersen, improved response rates in CLL patients who remained sensitive to chemotherapy drug fludarabine. The study showed a four-fold increase in 'CR/nPR' in these patients compared to those no longer responding to fludarabine.
Researchers at Dana-Farber Cancer Institute and Broad Institute develop a practical method for screening tumors for cancer-related gene abnormalities, paving the way for personalized medicine. The technique uses high-throughput genotyping to detect important mutations in oncogenes with high accuracy and sensitivity.
People with advanced cancer reported better quality of life when receiving spiritual support from religious communities and medical service providers. The study suggests that making a 'spiritual history' routine part of patient care can improve patients' well-being at the end of life.
A new study found that hairy cell leukemia survivors have an increased risk of developing certain cancers, including Hodgkin lymphoma and thyroid cancer. Meanwhile, a new test may be able to identify patients with a specific type of gene mutation that indicates an inherited form of colorectal cancer or potential response to certain drugs.
Scientists have linked telomere loss to both cancer and aging by visualizing chromosomes of cells from patients with Werner Syndrome. Rebuilding structures called telomeres significantly blocks genetic damage seen in cells of patients with Werner Syndrome.
Researchers at UT Southwestern Medical Center have found a new biomarker test that can predict the recurrence of bladder cancer in patients. The test uses molecular biomarkers to identify patients who are more likely to experience cancer recurrence, allowing for personalized treatment options.
Researchers investigate fatigue in various populations, finding distinct definitions for tiredness, fatigue, and exhaustion. The study aims to prevent progression from tiredness to exhaustion, emphasizing the importance of recognizing changes consistent with fatigue and exhaustion.
Researchers at Georgetown University Medical Center found that young cancer survivors are at risk of developing unhealthy behaviors, including smoking, lack of exercise, and inadequate sun protection. The study suggests that these behaviors can increase the risk of cancer recurrence and chronic disease in adulthood.
Researchers at University of Texas M. D. Anderson Cancer Center found that aspirin significantly improves survival rates among cancer patients with low platelet counts who experience heart attacks, even when taking anticoagulants. Aspirin also showed benefits for patients with normal platelet counts.
A new surgical technique, 'beavertail' surgery, has given back the ability to swallow to patients with tongue cancer. The procedure involves modifying an existing technique by adding a 'jellyroll' of fat and connective tissue to replace diseased tongue tissue.
A study found that chemotherapy with gemcitabine significantly delayed cancer recurrence in patients following pancreatic cancer surgery. The estimated median disease-free survival was 13.4 months for the gemcitabine group compared to 6.9 months for those without chemotherapy.