Articles tagged with Cancer Patients
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A new study published in the Journal of the National Cancer Institute found that prostate cancer patients treated by experienced surgeons have a lower risk of recurrence five years after surgery. The study analyzed data from over 7,700 patients and found that surgeons with more experience had better outcomes, with nearly 70% fewer recu...
A study published in the Journal of the National Cancer Institute found that experienced surgeons perform more successful prostate cancer surgeries, with a steeper learning curve. As surgeons gain experience, patient outcomes improve, but beyond 250 operations, additional experience has little influence on cancer recurrence rates.
A new study published by the American College of Cardiology found an association between low cholesterol levels and increased cancer risk. The research suggests that patients with high doses of statins may be at a higher risk of developing certain types of cancer.
A Stanford University School of Medicine researcher led by David Spiegel showed that support groups improved quality of life for participants with metastatic breast cancer, but didn't extend overall survival. However, a subgroup of patients with an aggressive form of breast cancer did experience a survival benefit from the therapy.
Researchers found adult leukemia survivors are less active than the general population, with those who received cranial radiotherapy showing the lowest levels of physical activity. This decreased physical activity increases the risk of obesity, cardiovascular disease, and mortality in these patients.
Researchers have developed an algorithm that can match any tumor cells with the most effective anti-cancer treatments, predicting clinical responses and identifying new compounds. This 'coexpression extrapolation (COXEN) system' has been successfully tested on bladder cancer cell lines and shows promise for other types of cancer.
A recent study by McMaster University shows that sperm banking can preserve fertility in adolescents and young adult males with cancer. The study found a 36% success rate using intrauterine insemination and a 50% success rate using in vitro fertilization.
A retrospective study published in The Lancet found no excess risk of cancer among individuals who received blood products from donors with previously diagnosed cancers. The study included over 12,000 exposed individuals and 342,082 unexposed individuals, concluding that long-term cancer survivors might be a safe donor group.
A study estimates that radiation exposure from cardiac CT scans increases the lifetime risk of cancer, with higher risks for women and younger individuals. The study suggests using alternative diagnostic modalities for young individuals and weighing the risks and benefits of each test.
Researchers suggest taking oral targeted cancer therapies like lapatinib with food to increase absorption and reduce dosage, resulting in significant cost savings. This approach could cut the needed dose of lapatinib by at least 60% and lower its monthly cost from $2,900 to $1,740.
The Case Comprehensive Cancer Center has received a $25.5 million award from the National Cancer Institute, representing a 10% increase in funding. The center, one of only 40 nationwide to receive an increase, will allocate $5.1 million annually for five years.
A recent study found that nodal status is the strongest determinant of outcome after neoadjuvant therapy for esophageal cancer. Patients with complete pathological responses had better survival rates, but only if they also had no nodal involvement.
Researchers at Biodesign Institute have received nearly $9 million in grants to develop a preventive vaccine against breast cancer. The team aims to identify common signatures across various breast tumors using genomics, proteomics, and immunology.
A review of published literature found that delays in childhood cancer diagnosis are short but the impact on prognosis remains unclear. The study suggests that delays can be attributed to gatekeeper-type healthcare systems, clinical presentation, stage of disease, and parent/patient factors.
Pawel Walewski, a health editor with Poland's biggest selling weekly magazine Polityka, has been awarded the European School of Oncology's Best Cancer Reporter Award for 2007. The award recognizes his outstanding cancer reporting and aims to promote better quality media coverage of cancer.
A landmark study finds that HIV/AIDS patients are 11 times more likely to develop Hodgkin's lymphoma, while transplant recipients face a similar increased risk for several types of cancer. Immune deficiency is the common factor driving these higher cancer rates in both groups.
Researchers identified promising biomarkers in urine samples, including one linked to liver and ovarian cancer. The goal is to create a simple, fast, and noninvasive test for early detection, potentially avoiding painful procedures.
Cancer is a major cause of disease and mortality worldwide, requiring a strong political signal for alliance and concerted actions. The Round Table on Health Strategies in the European Union will focus on creating capacity building for effective policies and programs to address cancer.
Dr. Insoo Bae receives $2 million Komen Award to develop novel prevention strategies for women with BRCA1 mutations. His research focuses on identifying environmental carcinogens that increase the risk of breast cancer in genetically predisposed individuals.
The Netherlands Cancer Institute received the ESMO Lifetime Achievement Award for its outstanding contributions to translational research in breast cancer. The team's discovery of a gene-signature has led to improved prognostic testing and reduced adjuvant chemotherapy in pre-menopausal patients.
Patients treated with Tarceva who develop a moderate to severe rash experience longer survival without disease progression compared to those with mild rashes or none. The analysis found that more severe rashes were associated with improved clinical outcomes.
Scientists successfully extracted and froze eggs from ovarian tissue of girls as young as 5 years old, a breakthrough in preserving fertility in young cancer patients. The study found an average of 8.5 eggs per patient, with a 32% success rate in maturing the eggs in vitro.
Researchers have developed a new tool that uses patient characteristics such as age, gender, race, and tumor site to estimate conditional survival. This will enable personalized predictions of prognosis for head and neck cancer patients.
Scientists, oncologists, and critics explore the use of ESAs, which can boost oxygen-carrying red blood cells and improve quality of life, but may be overprescribed due to cost and drug company influence. The debate highlights the need for fair and balanced review of data to ensure patients' needs are met.
Researchers at Georgetown University Medical Center have found a new molecular mechanism that may cause spontaneous liver cancer, but also identified a potential cure. By reintroducing the ELF gene to cancer cells, proteins driving cell division and growth can be kept in check, suggesting an effective new therapy.
The Damon Runyon Cancer Research Foundation has renewed its investment in young clinical cancer investigators, providing $2.25 million to support the development of their cancer research programs. Five new awardees will receive funding to investigate various types of cancer, including leukemia, lymphoma, and esophageal cancer.
The National Cancer Institute has launched a three-year pilot program to enhance cancer care in community hospitals across the US. The program aims to improve patient outcomes by facilitating collaboration between private-practice oncologists and NCI research, as well as exploring ways to share medical information electronically.
Patients with advanced-stage cancer struggle with maintaining both sleep and waking states, experiencing reduced nocturnal sleep quantity and quality. Demographic factors, such as age, education level, and marital status, may play a role in poor sleep outcomes among this population.
BRCA2 mutation carriers have a higher risk of developing aggressive and lethal prostate cancer, with younger onset and advanced-stage disease, according to a study published in the Journal of the National Cancer Institute. The study suggests that studying gene expression patterns in prostate cancers may help predict progression.
A 12-year review of skin cancer data in Northern Ireland found that wealthy individuals and older adults are disproportionately affected. The study also shows a significant increase in skin cancer rates, with malignant melanoma being the most common serious form of skin cancer.
A special publication from the University of Rochester Medical Center aims to improve understanding and management of cancer-related fatigue. Studies show that exercise and support groups are effective in helping people cope with this challenging side effect.
Two research teams developed models to predict NSCLC patient outcomes based on protein patterns. The new models, validated in independent groups, could help physicians decide treatment options for patients with NSCLC. Researchers identified a 25-signature proteomic signature associated with increased survival among NSCLC patients.
A review of nine randomized trials shows that patients treated with cisplatin lived slightly longer than those treated with carboplatin, with a median survival of 9.1 months compared to 8.4 months. However, the difference in survival was not statistically significant for all patient groups.
Four-year data from two large clinical trials found that trastuzumab significantly improves disease-free survival and overall survival rates in women with HER2-positive breast cancer. The study showed a 52% decrease in the risk of disease recurrence and a 35% reduction in mortality rates compared to chemotherapy alone.
Researchers have confirmed that arsenic trioxide significantly improves patient survival in newly diagnosed acute promyelocytic leukemia (APL) patients. Nearly 600 patients participated in a six-year phase III study, showing improved disease-free rates and longer survival compared to standard chemotherapy alone.
Women with early-stage breast cancer who reported hot flashes while on tamoxifen therapy had a lower risk of recurrent breast cancer than those without hot flashes. Hot flashes were a stronger predictor of outcome than age or hormone receptor status.
A recent study found that antidepressant sertraline does not improve symptoms or survival in advanced cancer patients without major depression. The researchers concluded that the overmedicalisation of these patients should be avoided, and treatment with sertraline should be reserved for cases with a proven indication.
The OHSU Cancer Institute study found that sipuleucel-T vaccine slowed the rate of rise of serum PSA in exploratory analyses, but did not significantly delay cancer progression. The treatment also showed a favorable safety profile with common side effects like fatigue and chills.
A multicenter Phase II study of enzastaurin as a second- or third-line treatment for NSCLC found a median progression-free survival of 1.9 months and an overall survival rate of 46.3% at 12 months. The most common toxicity was fatigue.
A pilot study by Mayo Clinic researchers found that high-dose American ginseng improves fatigue and vitality in cancer patients. Patients receiving the highest dose showed significant improvements in overall energy levels, mental, physical, spiritual, and emotional well-being.
A new study published by Duke University Comprehensive Cancer Center found that patients with chronic illnesses like diabetes or heart disease are no more likely to receive an early cancer diagnosis due to frequent healthcare interactions. Screening is still crucial regardless of medical management.
A new study by Duke University Comprehensive Cancer Center researchers shows that E Tables may be useful in collecting patient history data and conducting clinical research. Patients report being satisfied with the tablets and finding them comparable to paper forms in terms of data quality.
A large Phase III study found that shark cartilage extract AE-941 has no benefit when combined with chemotherapy and radiation for patients with advanced non-small cell lung cancer. The study did not meet its primary endpoint: survival, and the researchers cast major skepticism on the efficacy of shark cartilage products.
Patients with stage four cancer have less quality sleep, which is linked to functional performance, mental health, and pain status. Poor sleep quality can be a critical factor in cancer treatment, highlighting the need for effective symptom management.
Researchers have identified C-reactive protein (CRP) as a strong indicator of survival for men with advanced prostate cancer. The study found that higher levels of CRP are associated with shorter survival and lower response to chemotherapy.
The partnership aims to create programs and provide grants that support tangible improvements in access to and delivery of cancer care, particularly for disparities and clinical trials. The initiative also focuses on solutions to the projected shortfalls of the oncology workforce and addresses the unique needs of cancer survivors.
A blood test detecting tumor-related proteins may help monitor treatment effectiveness and predict cancer recurrence. Patients with low protein levels were more likely to remain in remission, while those with high increases were at higher risk of cancer return.
A new study found that only 9% of breast cancer specialists adhere to guidelines for follow-up care, with varying frequencies of mammograms and discharge times. The research highlights the need for improved coordination between specialists and general practitioners to provide better patient care.
A study of 666 head and neck cancer patients found that 38.1% discontinued work due to cancer and treatment, with fatigue being the leading factor. The study highlights the need for interventions to minimize disability after treatment and provide more information about employment to patients.
A new study found that cancer survivors are more likely to attend support groups compared to people with other chronic conditions. However, few survivors receive referrals to such programs from their physicians. The study also revealed that predictors of use include female gender, Caucasian race, and symptoms of depression or anxiety.
Reolysin works synergistically with standard anti-cancer drugs, providing stronger responses than either agent alone. It also primes patients' immune systems against their particular cancer, leading to additional cancer cell killing and long-term remissions.
A report by European Society for Medical Oncology reveals stark inequalities in access to cancer treatment globally. Key findings include that Austria, France, and the US have high uptake of new cancer drugs, while countries like New Zealand, Poland, and South Africa have low uptake.
Two studies by Dartmouth Medical School researchers reveal that US movies deliver billions of smoking impressions to American teens, with youth-rated movies delivering 61% of the total images. The studies also found that high-impact movies, mostly rated PG-13, deliver over 100 million smoking impressions each.
A recent study found that MR imaging can predict prostate cancer recurrence in patients with extracapsular extension. The study, which analyzed 74 men with biopsy-proven prostate cancer, identified features on imaging that indicated a higher risk of metastasis.
Researchers at the University of Illinois Chicago are studying fatigue in cancer patients undergoing stem cell transplants using ecological momentary assessment. Patients use a wearable device to record their fatigue intensity, providing an instant measurement of symptoms that can interfere with daily functioning.
Research grants aim to reduce suffering for seriously ill patients and their caregivers, with studies focusing on communication, treatment advances, and caregiving support. The initiative supports clinician investigators conducting patient-oriented research in palliative care.
A recent study by researchers at the University of Pennsylvania School of Medicine found no evidence linking psychotherapy to increased survival rates among cancer patients. Despite previous studies suggesting a potential benefit, the authors conclude that psychotherapy can improve quality of life without extending lifespan.
Using erythropoiesis-stimulating agents (ESAs) to treat non-chemotherapy-related anemia in cancer patients may increase the risk of death, thromboembolic events, and potentially even cancer growth. Researchers recommend a cautious approach until further scientific data is available.
Patients with metastatic colorectal cancer treated with EGFR-targeted monoclonal antibodies experience significant magnesium loss, affecting up to 97% of patients. The study suggests that identifying high-risk patients through patient characteristics could aid early intervention to prevent severe hypomagnesaemia.
A new stent has been shown to relieve GI upper cancer distress by incorporating an anti-reflux valve, which reduces backflow of intestinal contents into the bile duct. The study found that patients with the Dua stent had a longer median of 145 days without complications compared to those with standard stents.