Articles tagged with Cancer Patients
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Researchers at the University of Pennsylvania School of Medicine have identified a new protein called Tribbles associated with acute myelogenous leukemia (AML). The study found that Tribbles induces AML by inactivating the C/EBPá protein, providing a potential therapeutic target.
A new procedure at UCLA's Jules Stein Eye Institute uses fine-needle aspiration to collect cancer cells from the living eye and predict high-risk tumors. The test has shown promise in reducing mortality rates among ocular melanoma patients.
Researchers identified 142 candidate indicators of quality care for colorectal cancer surgery, including surgical credentials, preoperative evaluation, and postoperative management. The expert panel rated 92 indicators as valid, suggesting these can be used to measure care quality and create improvement programs.
A new set of quality indicators has been created to evaluate the quality of care received by patients undergoing colorectal cancer surgery. The guidelines cover aspects of surgical care, including pre-operative evaluation and post-operative management, to provide a valuable tool for improving patient outcomes.
Research reveals that obese patients are one-third more likely to experience cancer recurrence, while underweight patients face a doubled risk of death from non-cancer causes. The study suggests that excess weight can lead to reduced treatment efficacy due to concurrent illnesses.
A new study found that colon cancer patients with a body mass index of 35 kg/m² and higher had a significantly increased risk of cancer recurrence or death from colon cancer. Underweight patients, on the other hand, had a higher risk of death from non-colon cancer causes.
A recent study found that nearly half of newly diagnosed breast cancer patients exhibit clinically significant emotional distress, including symptoms of major depression and post-traumatic stress disorder. The most common sources of distress were related to the cancer diagnosis, treatment uncertainty, and physical problems.
A study published in CANCER reveals that adolescent and young adult cancer patients value social connections with peers as a high priority, contrary to physician beliefs. Researchers found that meeting other young people who share a common experience helps address concerns such as coping with uncertainty and body changes.
Women cancer carers face unique challenges, including 24/7 caregiving responsibilities, isolation, and lack of emotional support. In contrast, male carers tend to view caring as a competency task with less emotional labor.
Researchers developed a potential vaccine targeting HER-2/neu overexpression in early stage breast cancer, yielding promising results for women at high-risk. The study found that nearly all patients exhibited an immune response and many developed protein antibodies to fight the cells.
A study published in the Society of Integrative Oncology's Third International Conference found that antioxidant therapies do not hinder the effectiveness of radiation therapy for prostate cancer. The study, conducted by Cancer Treatment Centers of America, reviewed PSA levels of prostate cancer patients after receiving radiation thera...
A MEK enzyme inhibitor has shown long-lasting stable disease in patients with advanced solid cancers, inhibiting key targets and reducing cell proliferation. Phase II trials have been initiated for melanoma, pancreatic, lung, and colon cancers.
Researchers at the University of Pennsylvania School of Medicine discovered how KSHV subverts a normal cell process to promote tumor growth. By tricking tumor suppressors VHL and p53 into being destroyed, KSHV allows cancer cells to grow unchecked.
A University of Pittsburgh study demonstrates that intensity-modulated radiation therapy (IMRT) can be uniformly delivered in a large health care system through centralized planning and treatment. This approach enables patients to receive consistent quality of care despite geographic distances.
A retrospective study found that three-dimensional treatment planning reduced feeding tube dependency in 62% of patients. Higher T stages and two-dimensional treatment planning were independent predictors of feeding tube dependency.
A consensus statement published in Annals of Surgical Oncology calls for heated chemotherapy after colon cancer surgery to optimize patient survival. The treatment, known as HIPEC, has shown promising results with a median survival of greater than 20 months compared to six-month survival with traditional intravenous chemotherapy.
Researchers at Thomas Jefferson University found that a specific gene, Dachshund, helps predict breast cancer prognosis. The study showed that higher expression of this gene is associated with better patient outcomes.
The use of videoconferencing in a twinning program between Jordan and Canada improved patient care, compliance, and trust. The program showed positive impacts on treatment changes, second opinions, and introduction of new concepts in pediatric oncology.
Rita Davis-Goldsberry, a breast cancer survivor, received the Survivor Circle Award for her advocacy work with uninsured patients. Barbara Knight-Meyers, Ph.D., was recognized as a Distinguished Honoree for her volunteer work at Insight Seminars. Both women have given back to their community after receiving treatment for cancer.
A study found that women with premenopausal breast cancer and 4+ positive lymph nodes may experience improved 10-year cancer-free survival with aromatase inhibitors. However, patients over 60 years old or those with advanced age, comorbidities, or fewer positive lymph nodes may not benefit from additional therapy.
A new study found that African-American patients with breast cancer have more aggressive tumors and poorer outcomes due to differences in tumor biology. The research controlled for healthcare access biases and found that African-American race was independently associated with poor survival rates.
A Canadian oncologist warned doctors to be aware of the potential risk of suicide among cancer patients. The study found that American cancer patients are more than twice as likely to kill themselves as the general population. The risk varies according to factors such as gender, prognosis, and type of cancer.
The University of Liverpool, Royal Liverpool University Hospital and Clatterbridge Centre for Oncology are merging to create a cancer research centre, enabling global clinical trials of new therapies. The centre will be funded by Cancer Research UK and will double the number of patients in early phase clinical trials.
A study of childhood cancer survivors found that their children were more likely to be born early or underweight compared to siblings of cancer-free individuals. The risk was highest for children whose mothers received pelvic radiation as treatment.
A study found that elderly women with breast cancer are often under-staged, under-treated, and miss out on life-saving treatments. The researchers analyzed data from a tumor registry database and found that 70% of patients were in early stages of cancer but missed out on lymph node evaluation.
Researchers at the University of Virginia are developing an office-based cancer screening test using biomarkers in urine to detect early signs of cancer. The goal is to improve detection and treatment outcomes, as current tests often rely on invasive procedures or delayed diagnoses.
Researchers discovered a new target for future colon cancer treatments, a molecule involved in 85% of colon cancer cases. CTBP's accumulation in tumor cells with APC mutations leads to low retinoic acid production, causing improper cell development.
A study by McGill University Health Centre researchers finds that sperm banks are unpopular with patients due to lack of accurate information and improved doctor-patient communication. Quebecers are less likely to choose sperm banking than patients of immigrant descent.
A Phase II trial of Revlimid found that over 75% of MDS patients reduced their need for transfusions, with two-thirds completely freed from transfusions. In 45% of cases, no detectable cancer was found after treatment.
Older women with breast cancer often receive inadequate care due to ageism, despite being half of new patients each year. Researchers call for considering overall health and frailty in treatment decisions.
Margaret Foti, AACR CEO, receives the Association of American Cancer Institutes Distinguished Service Award for her leadership and advocacy in advancing cancer research. The AACR has grown to over 24,000 members under her tenure, and she has launched several high-quality journals in the field.
The Geoffrey Beene Cancer Research Center will focus on two complementary programs at Memorial Sloan-Kettering, one in Cancer Biology and Genetics, the other in Human Oncology and Pathogenesis. The center aims to translate revolutionary advances in understanding cancer into dramatic progress in controlling it.
A study by Memorial Sloan Kettering Cancer Center found that high-dose intensity modulated radiation therapy (IMRT) achieved a 89% disease-free rate for patients with prostate cancer after an average of 8 years. The treatment also showed improved quality of life by reducing side effects and maintaining urinary continence.
A study found that less than one-third of gastric cancer patients had adequate lymph node assessments, leading to compromised survival. Median survival in regions with the highest ALNA rate was 33 months, while in regions with the lowest rate it was only 17 months.
A new study found that black patients with bladder cancer are 35 percent more likely to die of the disease than white patients. Black women in particular had more aggressive tumors and lower survival rates compared to white men and women and black men.
Researchers will develop new methods to evaluate and test tobacco products, providing information to smokers for informed choices. The study aims to determine if these 'safer' alternatives truly reduce health risks and exposure to carcinogens.
Radiation therapy significantly reduces risk of subsequent mastectomy and invasive breast cancer in both low- and high-risk patients with ductal carcinoma in situ (DCIS). Autoimmune conditions are also associated with increased risk of Hodgkin lymphoma, according to two new studies.
Researchers developed a new method to detect oncogene mutations in human cancers, which could be used in real-time to match patients with available targeted therapies. The technique uses high-throughput mass spectrometry-based genotyping and was validated in over 1,000 tumors, representing 15 different cancer types.
A new protocol using the protein tNOX has shown promise in detecting lung cancer early in smokers and nonsmokers. The test involves measuring levels of tNOX in the blood, with low false positive rates, making it a potential screening tool for early detection.
Researchers investigated association between TNF blocker use and cancer risk in RA patients. They found no increased risk of lymphoma or tumors associated with anti-TNF therapy over methotrexate use. The study used a large sample of patients and found an overall difference in estimated cancer risk less than 5 percent.
Finasteride increases PSA testing's ability to detect prostate cancer with higher sensitivity and accuracy, according to a study published in the Journal of the National Cancer Institute. The study found that men taking finasteride had improved PSA test performance compared to those taking a placebo.
The Jess and Mildred Fisher Center for Familial Cancer will expand clinical and research programs at Lombardi Comprehensive Cancer Center, providing automated cancer risk assessment and genetic predisposition research. The center also endows the Cecilia F. Rudman Arts and Humanities Program Fund, enhancing arts therapy and patient care.
A new study found that over half of men with lower-risk prostate cancer received aggressive treatment, despite active surveillance being a viable option. Men under 55 were more likely to receive surgery, while those aged 70-74 were more likely to receive radiation.
A new study suggests that low-risk prostate cancer patients are being overtreated with aggressive therapies such as radiation and surgery. Waiting for treatment to be necessary may improve patient outcomes and reduce unnecessary harm.
A new study reveals that racial disparities in cancer outcomes may be attributed to problems in doctor-patient communication. African-American patients tend to receive less information and are less actively involved in their medical decisions, leading to potential negative impacts on care.
A new study suggests that post-transplant lymphoproliferative disorder (PTLD) arises when immune cells called scout cells become weakened, allowing the Epstein-Barr virus to cause cancer. The study identifies a mechanism that may explain why some patients develop PTLD and others don't.
A new study suggests that women with endometrial cancer should be screened for inherited Lynch syndrome mutations, which are associated with a high risk of several cancers. The study found that 1.8% of newly diagnosed endometrial cancer patients have these mutations, highlighting the importance of genetic screening and early detection.
The study found that CAD increased cancer detection by 13.3% in screening-detected cancers and 14.2% for ductal carcinoma in situ (DCIS).CAD also improved recall rates and reduced false negatives, with the greatest impact on symptomatic patients.
A new study finds that hospice enrollment rates vary more by health center than individual patient characteristics. Additionally, a meta-analysis suggests that high processed meat consumption is associated with an increased risk of stomach cancer, while another study identifies a potential target for leukemia treatment and notes the pe...
Researchers found that combining chemotherapy with radiation therapy after surgery significantly improves survival rates for patients with advanced pancreatic cancer. The study showed a median survival time of 18.3 months, compared to the national average of 11 months.
A study found that cancer patients who used information services and online support groups experienced improved learning outcomes. The analysis revealed that interactive services also predicted improved learning outcomes, while interacting with an online expert did not contribute to benefits.
A meta-analysis of 59 trials found little evidence that diet affects cancer survival or prognosis, while a study on garlic and vitamin supplements showed no benefit in reducing precancerous gastric lesions to cancer. Long-term use of vitamins and garlic supplements had no effect on gastric cancer incidence.
Researchers have developed a non-invasive method to detect bladder cancer using DNA found in urine, while a study suggests high pesticide exposure increases the risk of liver cancer. Additionally, a growth factor has been found to inhibit lung tumor metastasis by stopping blood vessel growth and breaking down specific proteins.
Using mass spectrometry, researchers identified three activating mutations of the tyrosine kinase JAK3 in AML cells, leading to a potential new treatment target. The study's fast and affordable approach could help analyze cancer cells for mutations in just weeks.
Stanford University researchers developed a 3D PET/CT imaging technique that provides a visual navigation of organs, allowing for better detection and characterization of cancer. The technology has potential for presurgical visualization, guiding biopsies and identifying tumor 'hot spots', enabling more precise diagnosis and treatment.
Researchers at the University of Pennsylvania School of Medicine used molecular imaging techniques to discover small molecule compounds that can restore normal p53 function in cancer cells, killing human tumor cells. The findings emphasize the growing role of imaging technology in individualized cancer treatments.
A new study published in The Lancet Oncology reveals that boost radiotherapy is an effective strategy to prevent cancer recurrence in young women with ductal carcinoma in situ (DCIS). Researchers found that the most effective approach was radiotherapy with a boost, which significantly reduced the risk of cancer return.
The publication of consensus recommendations for FDG PET usage is expected to reduce variability in clinical trials, leading to shorter trials and improved treatment outcomes. The guidelines provide a valuable reference for incorporating PET into clinical trials and promoting drug development.
Researchers at Saint Louis University School of Medicine found that heated blankets can significantly reduce false-positives in cancer scans caused by brown adipose tissue. The blankets reduced the uptake of tracer by 62%, compared to 30% with traditional drugs.
A new approach to lymph node examination, called targeted lymph node examination, has been shown to improve staging of colon cancer. This technique uses blue dye to identify the sentinel node, which is the first node to receive lymphatic drainage from a primary tumor site.