Articles tagged with Cancer Patients
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A study assessing H-pylori status in patients with gastric adenocarcinoma found that positive individuals had improved survival rates compared to those negative for the bacteria. The results suggest that H-pylori status can be a useful tool in clinical practice to distinguish between high and low risk patients.
Scientists have identified a second molecular pathway that enables cells to adapt to low-oxygen environments, reducing protein synthesis to conserve energy. This finding sheds light on the physiology of cancer and cardiovascular disease, where oxygen levels are often abnormally low.
A study led by Vanderbilt-Ingram Cancer Center aims to determine the risk level for birth defects and other adverse outcomes in children of cancer survivors. Researchers analyze data from Denmark and Finland, where extensive patient information is available, to quantify risks based on chemotherapy and radiation exposure.
Researchers analyzed 28,689 cases of non-small cell lung cancer, finding a stronger association between tumor size and metastasis for solid tumors. The study suggests that smaller tumor sizes are associated with higher curability rates, even for micrometastases undetectable by current techniques.
Researchers from Georgetown University Medical Center have discovered that certain vegetables, such as broccoli and soy beans, can increase the levels of BRCA1 and BRCA2 proteins in damaged DNA. This could explain how eating vegetables cuts a person's risk of developing cancer.
A large study published in JAMA Network found that a low-fat diet had no significant impact on the incidence of invasive breast cancer in postmenopausal women. The Women's Health Initiative Dietary Modification Trial involved 48,835 women and followed their dietary habits over an 8.1-year period.
A recent study suggests that lung cancer survival rates may be tied to access to standard cancer care, rather than racial disparities. Researchers analyzed data from 995 patients with advanced small cell lung cancer and found that equal treatment yielded the same outcomes for black and non-black patients, regardless of stage or ethnicity.
PET imaging has shown to be a valuable tool in improving cancer care management by accurately assessing treatment outcomes and monitoring tumor response. Studies have demonstrated that PET can detect residual scar tissue rather than viable tumor, leading to changes in how PET is used in cancer care.
Researchers found that early identification of patients who would benefit from non-surgical treatment improved survival rates. The study, published in the Journal of Clinical Oncology, showed a significantly better cure rate when matching the right treatment to the patient's tumor biology.
Research found no significant association between hospital case volume and short-term mortality after ovarian cancer surgery. However, patients treated by gynecologic oncologists had the best outcomes and lowest mortality rates. Long-term outcomes were slightly more favorable for high-volume hospitals, but this difference was modest.
A large-scale analysis of stage I endometrial cancer patients reveals that adjuvant radiation therapy significantly improves overall and relative survival. Adjuvant RT shows particular benefits for patients with stage IC/grade 1 and grades 3 and 4 disease, resulting in lower death rates.
A study of 2337 lung cancer patients with advanced disease found that nearly 1% survived for five years after receiving low-dose palliative radiation therapy, including 18 who achieved an apparent cure. Prognostic factors were not found to predict survival in these patients.
Researchers found that bexarotene reduced tumor burden by almost 50% and inhibited malignant tumor progression by about 50% in mice. The study suggests bexarotene is a potentially viable lung cancer prevention candidate.
A non-invasive urine test, NMP22, can detect recurrent bladder cancer more effectively than traditional cytology methods. This assay detected 99% of malignancies when combined with cystoscopy, improving patient surveillance and outcomes. Cystoscopy alone identified only 91.3% of cancers.
A new point-of-care test has been shown to detect recurrent bladder cancer more effectively than traditional lab tests. The NMP22 assay detected 49.5% of recurrences, while urine cytology detected only 12.2%, resulting in a significantly higher detection rate when used with cystoscopy.
A new urine test, BladderChek, detected nearly all recurrences of bladder cancers with a higher accuracy rate than conventional tests. The test, used in conjunction with a diagnostic scope, detected 99 percent of recurring bladder cancers.
A study of 200 patients with head and neck cancer found that those with lower quality of life one year after treatment were more likely to die. The researchers discovered a correlation between steady-state QOL and long-term survival, suggesting that adjusting to the diagnosis and treatment may be crucial for better outcomes.
A study of 257 breast cancer patients aged 55+ found that Hispanic women were more likely to identify a family member as the final decision-maker for treatment. This led to lower rates of breast-conserving surgery compared to mastectomy in these patients. The study highlights the importance of acknowledging patients' family members in ...
A team of scientists has found that artificially increasing the activity of the p53 protein in laboratory mice with a hereditary predisposition for cancer significantly reduces tumor development. The study suggests that giving p53 just enough slack in its leash could help patients avoid developing cancer.
A study found that nearly half of patients treated with the PC combination experienced a clinical benefit, including stable disease and tumor size reduction. Researchers believe this combination has a beneficial role, especially for patients with poor treatment outcomes.
Two new studies uncover significant associations between certain autoimmune disorders and an increased risk of non-Hodgkin lymphoma. Meanwhile, a separate study suggests that consuming carbonated soft drinks may decrease the risk of esophageal adenocarcinoma, contrary to previous findings.
A four-month study found that art therapy sessions improved eight out of nine symptoms in cancer patients, with significant reductions in pain, tiredness, and anxiety. Patients reported feeling energized and benefited from the creative process as a form of expression.
The study reveals that the EBNA3C protein recruits a complex to degrade the retinoblastoma protein (Rb), leading to uncontrollable cell proliferation. This finding holds promise for developing new treatments for EBV-associated B cell lymphomas and other blood cancers.
A study by Washington University psychologist Teresa L. Deshields found that most breast cancer survivors adjust well to survivorship within two weeks, with depressive symptoms dropping significantly after treatment. The study suggests that oncologists can reassure patients that their quality of life will improve quickly.
A study found that informational campaigns alone may not be enough to increase participation in cancer clinical trials among black and Asian American patients. Lack of awareness about trial costs being covered by insurance is a significant barrier to participation, especially among those with lower incomes and education levels.
Researchers propose a three-step process for cancer development, where epigenetic changes occur first, followed by genetic mutations. This new understanding may lead to earlier detection and treatment of cancer, similar to cholesterol-lowering drugs preventing heart disease.
A study by Northwestern University found that postmenopausal white women with a history of non-melanoma skin cancer are twice as likely to develop cutaneous melanoma. Regular skin checkups are crucial for these high-risk individuals to reduce the incidence of deadly melanoma.
A study of 71 smokers found that guided imagery techniques increased smoking abstinence rates by 14 percentage points. The results suggest that clinicians can use these techniques to aid patients in quitting smoking, contributing to the country's goal of reducing smoking prevalence to 12% by 2010.
Researchers found that a structured psychoeducational intervention improved caregiver quality of life and reduced distress for those caring for terminally ill cancer patients. The study suggests expanding end-of-life care studies to include other populations.
A new study found that radiotherapy significantly reduces breast cancer mortality and local recurrence rates, particularly in women with lymph node involvement. Radiotherapy can improve long-term survival, especially for those with a history of breast-conserving surgery or mastectomy.
A new programmable chip has been developed to accelerate the production of molecular imaging molecules for PET, with a 93% accuracy in detecting Alzheimer's disease. The technology enables mass production of diverse imaging molecules and applications for PET in biology and pharmaceutical research.
Researchers found marked improvement in chronic myeloid leukemia and acute lymphocytic leukemia patients treated with AMN107. The drug, taken in pill form, outperforms Gleevec by up to 50 times in shutting down cancer-causing tyrosine kinase.
The Mayo Clinic Cancer Center has reported significant advancements in quality of life assessments for cancer patients. The researchers tackled philosophical and statistical issues to develop practical methods for capturing QOL data. They emphasized the importance of including patient perspectives to provide personalized care.
A randomized clinical trial of dose-dense chemotherapy in early-stage breast cancer found the regimen to be safe, with a 13% reduced risk of death. However, the dose-dense treatment increased acute toxic effects such as anemia and bone pain, but these were mild and easy to manage.
Researchers developed a new treatment that reverses traditional treatment steps, reducing tumor size and increasing surgical removal options. The treatment has shown significant success in shrinking tumors, with no progression or recurrence observed after surgery.
A new study suggests that video-assisted thoracoscopic surgery can be a viable option for older patients with early-stage non-small cell lung cancer. The procedure has been shown to have low risk and good success rates, allowing patients to avoid the consequences of widespread cancer.
Researchers found that chemotherapy with doxorubicin and cisplatin extended disease-free survival by 50% and overall survival by 13% compared to radiation therapy. Serious side effects were more common in the chemotherapy group, but a new regimen may be less toxic.
A new Stanford tool helps identify subtypes of kidney tumors based on gene activity, potentially leading to more targeted and effective treatments. The approach minimizes setbacks in clinical relevance by identifying relevant genes across multiple studies.
Patients who quit smoking around cancer diagnosis have improved disease outcomes, better QOL, and prolonged survival compared to continuing smokers. Targeted interventions combining behavioral therapy and pharmacotherapy show promise in addressing individual barriers to cessation.
New research suggests that smoking after cancer diagnosis can lead to poorer treatment outcomes, with up to one-half of patients continuing to smoke or relapsing. Tobacco use is now recognized as a critical variable in clinical trial results, and addressing it through cessation efforts can improve success rates and quality of life.
Researchers at Duke University Medical Center successfully tested eliminating CD25-expressing regulatory T cells using immunotoxin DAB389IL-2. This strategy improved tumor-specific T cell responses in cancer patients, enhancing vaccine efficacy.
Researchers found that megestrol acetate reduced weight loss and improved quality of life in patients with lung cancer and head and neck cancers undergoing radiation treatment. The study showed significant weight gain in the group receiving megestrol acetate compared to those on a placebo.
Researchers have discovered a novel bacterial protein azurin that can selectively target and kill cancer cells, while also using electric pulses to deliver a gene therapy that stimulates an immune system attack. Additionally, a small nanoparticle has been developed to reduce side effects of radiation and chemotherapy treatment.
Researchers link muscular dystrophy and cancer-associated muscle wasting to dysfunctional dystrophin glycoprotein complex. Cachectic patients with gastrointestinal cancers show dramatic reductions in dystrophin levels, highlighting the shared mechanism of DGC dysfunction as a critical characteristic.
A study of advanced cancer patients found that 12% met criteria for a major psychiatric disorder, while 28% received treatment and 17% discussed emotional complaints with providers. Notably, over half of those with psychiatric complaints had not accessed mental health services.
A terminal cancer patient, D.H., has seen his cancerous tumors shrink to 10% of their original size after increasing his intake of omega-3 fatty acids. The nutritional intervention was part of a case study published in the Nutrition and Cancer journal, showing promising results for cancer treatment.
Researchers found that drugs inhibiting MEK selectively inhibit growth of cancer cells with BRAF and RAS mutations, leading to clinical trials for patients with melanoma, colon, breast, and lung cancers. The study identifies a novel class of targeted therapies, which may be more effective and less toxic than traditional chemotherapies.
A Phase III trial demonstrated a significant increase in average time to progression with sunitinib treatment compared to placebo, leading to improved overall survival. Treatment with sunitinib was well-tolerated, with common side effects including fatigue and diarrhoea.
A study assessing anxiety, depression, and quality of life in Greek patients with cancer undergoing chemotherapy found that nearly a third experienced severe emotional distress. Routine screening for emotional distress is recommended to identify patients in need of psychological or pharmaceutical intervention. Additionally, research on...
A study of 304 recently diagnosed cancer patients found that 57% of pre-diagnosis CAM users continued to use it after diagnosis, with post-diagnosis use being almost universally helpful. The study highlights the importance of addressing psychosocial needs and communication barriers in cancer care.
A study of Chernobyl children with thyroid cancer found no association between ret rearrangement and radiation exposure. Instead, the age of diagnosis may be a significant factor in understanding the molecular biology of thyroid cancer.
A recent study found that post-treatment conception was successful in 71% of testicular cancer survivors within 15 years and 76% within 20 years. The success rate varied by type of treatment, with men treated with higher doses of chemotherapy having lower fertility rates.
Researchers followed nearly 1.7 million offspring and siblings of almost 850,000 people with cancer diagnoses to investigate familial cancer risks. The study found that daughters of breast cancer patients were more likely to be diagnosed with in situ breast cancer within a year of their mother's diagnosis.
Researchers have created an animal model of an immunotherapy approach that uses tumor cells and 'danger' signals to stimulate tumor immunity. The discovery enables further understanding and development of the approach, which has shown promising results in cancer patients.
Alcohol consumption is linked to increased ER-positive breast cancer risk in postmenopausal women. Tamoxifen treatment for 5 years reduces death from coronary heart disease compared to 2-year treatment, according to a new study. The gamma-linolenic acid found in herbal medicine has been shown to affect the expression of the Her-2/neu o...
Researchers found that IBS patients often believe it causes cancer, is caused by food allergies or intolerance, or changes in daily routine. Patients also reported significant concerns and effects on daily life, indicating a need for improved education and support.
Key decision-making tools were highlighted to improve patient outcomes, while patients and healthcare professionals stressed the importance of timely access to quality screening, diagnostic tests, and treatment. Experts emphasize the need for a unified voice to address systemic inequalities in cancer care across Europe.
Dr. Lippman's work has uncovered new means of treating and preventing several types of cancer through his research on molecular biology and carcinogenesis. His studies have also led to the development of molecular targeted drugs for cancer prevention, including trials for high-risk populations.
A hospital research team and a leading cancer professor express serious concerns about the effectiveness of the two-week wait target, which has not improved survival rates. They urge the Government to rethink the target and focus on targeting all stages of the cancer pathway for earlier diagnosis and treatment.
Researchers found that early vaccination with pneumococcus and T-cell vaccine can rebuild immunity in cancer patients after chemotherapy, with protection developing within a month. This study paves the way for personalized therapy using engineered T-cells to boost the immune system against tumors.