Articles tagged with Cancer Patients
Researchers at Memorial Sloan-Kettering Cancer Center discovered a novel mechanism that can enhance the function of AML1, a protein frequently impaired in acute leukemia. The study identified the methyltransferase enzyme controlling normal AML1 activity and demonstrated its ability to regulate transcription factors.
A recent study published in the Psychological Bulletin found that when couples face a cancer diagnosis, women are consistently and severely distressed. The researchers analyzed data from 43 studies worldwide and concluded that gender plays a greater role than who the patient is in coping with cancer.
The initiative aims to bring team-based science to bear on major cancer research questions, integrating expertise and resources to solve the most challenging problems. Twelve proposals were reviewed by an external scientific advisory panel, and four Keystone Programs were awarded $5 million in funding over five years.
Researchers developed artificial cell-like particles made of biodegradable material that can target specific diseases or infections. The new method enhances T cell activation by up to 45 times, addressing limitations of previous immunotherapy procedures.
Treating anemia with ESAs increases risk of VTE and death among cancer patients, according to a review of phase 3 trials. There was a significantly increased risk (57") of VTE among patients treated with ESA, while the risk of death was higher for ESA-treated patients compared to the control group.
A Northwestern University study found that cancer patients taking erythropoiesis-stimulating agents (ESAs) have a 10% increased risk of death compared to those who did not take the drugs. The study's findings suggest that ESAs may stimulate the growth of cancer cells, leading to shorter survival rates.
A study found that a single 20-minute expressive writing session can positively impact cancer patients' thoughts and feelings about their disease. Patients who reported changes in their thoughts and feelings after writing also experienced better physical quality of life three weeks later.
Optimal band imaging improves depression-type early gastric cancer diagnosis by clearly identifying contrasting demarcation lines between cancerous and noncancerous areas. This technology enhances capillary pattern and pit patterns in endoscopic images, leading to improved detection rates.
A new study found that uninsured patients are more likely to be diagnosed with advanced stage cancer compared to those with private insurance. The study, which analyzed over 3.5 million cancer patients, also showed that Medicaid-insured patients face similar risks, particularly for cancers with early detection methods.
A Dutch study found that only 17% of individuals who survive pediatric cancer receive follow-up care at age 35, highlighting the need for family doctors to be involved. The study suggests that shared care between dedicated clinics and family practitioners can increase surveillance for adverse effects.
Uninsured and Medicaid-insured US patients are more likely to present with advanced cancer at diagnosis than privately insured patients. The authors found that these disparities affect ethnic minorities and cancers with early detection potential, underscoring the need for adequate healthcare coverage.
Researchers found a biomarker that identifies men with a five-fold increased risk of prostate cancer recurrence if their tumors show silencing of the CDH13 gene. The study, which examined DNA methylation changes in 151 research subjects, suggests a potential tool to improve prediction accuracy and inform clinical practice.
A study published in the Journal of the National Cancer Institute found that HPV-positive head and neck cancer patients have higher response rates to chemoradiation therapy and better two-year overall survival rates compared to HPV-negative patients.
A study found that breast cancer survivors, especially older women, are at a greater risk of dying from non-cancer causes than from breast cancer. Factors such as pre-existing diseases like heart disease and osteoporosis are associated with this increased risk. The researchers also found that women with cancer cells in the lymph nodes ...
Researchers found 41 inaccurate statements on 18 websites, 5.2% of total analyzed web pages. Despite quality criteria, no combination could differentiate accurate from inaccurate content.
A study found that healthcare providers play a significant role in patients' likelihood of being screened for colorectal cancer. Patient barriers such as concerns about payment and fears of detection also impact screening rates. Interventions targeting both providers and patients are necessary to boost screening rates.
A new study found that 41 false statements appeared on 18 web pages (5.2%) and that websites with complementary or alternative medicine were 15.6 times more likely to have inaccuracies. The authors advise patients to be skeptical of online health information and consult a clinician before taking action.
The Simons Foundation's $10 million grant will support preclinical studies of new therapies for gliomas, a type of brain cancer. The goal is to develop treatments that target cancer cells and abnormal signaling pathways while sparing nearby sensitive tissues.
A comprehensive review of scientific literature found that cancer survivors use nutritional supplements at a higher rate than the general population, with breast cancer survivors reporting the highest use. However, research suggests that certain supplements may interfere with treatment or even accelerate cancer growth.
Researchers at UCLA's Jonsson Cancer Center have discovered biomarkers that can help personalize treatment for patients with advanced non-small cell lung cancer. These biomarkers may identify patients who will respond to the Celebrex and Tarceva combination therapy, sparing them from ineffective treatments.
Gas6 protein has proven successful in treating mice with anemia without causing side effects, while reinforcing EPO's effect. This could form the basis for a new treatment for patients where EPO is ineffective.
Researchers analyzed data from nearly 30,000 women with breast cancer and found that female surgeons were more likely to prescribe post-surgical radiation therapy. Women who received radiation had a surgeon trained in the US or with an M.D. degree compared to a D.O. degree.
A new study found significant racial and ethnic differences in the treatment and survival of patients with extremity soft-tissue sarcomas. Blacks had lower rates of surgeries that would have saved their arm or leg, higher death rates, and were least likely to receive additional treatments for improved survival.
A recent study by Beth Israel Deaconess Medical Center found that the majority of adverse events and device malfunctions associated with biliary stents occur during off-label use. Over 1 million patients received these devices for 'off-label' treatments between 2003 and 2006.
A systematic review found sorafenib significantly increases the risk of developing hypertension, particularly high-grade hypertension. Patients receiving sorafenib require close monitoring and effective management to prevent cardiovascular complications.
Research finds gastric cancer patients post-gastrectomy have high prevalence of osteoporosis (38.3%) and vertebral deformities. Screening by Dual-energy X-ray absorptiometry is recommended for those over 60 or with anemia/back pain.
A study found that two microRNAs, miR-191 and miR-199a, are associated with patient survival in high-risk acute-leukemia patients. These molecules may serve as targets for future therapies, offering hope for patients with limited treatment options.
A study published in Clinical Cancer Research demonstrates that a novel mass-spectrometry based proteomic profiling method is more accurate than traditional biomarkers in distinguishing liver cancer patients from patients with hepatitis C liver cirrhosis. The technique, SELDI-TOF MS, identified an 11-protein signature that accurately d...
A new study found that racial disparities in cancer care have persisted despite efforts to mitigate them. Black patients are significantly less likely than white patients to receive therapy for certain types of cancer, including lung, breast, colon, and prostate cancer.
A recent study by Yale researchers found significant racial disparities in cancer therapy, with black patients less likely than white counterparts to receive treatment for various cancers. Despite efforts to improve access to care, the disparities persisted, highlighting the need for continued work to address these issues.
Research identifies variations in cancer, enabling more precise treatment; childhood cancer experience differs from adults, with teens facing stigma and discrimination.
Researchers found a founder mutation in two large US families that may contribute to significant colon cancer cases. The mutation increases risk by 2-3 times by age 80, but can be prevented with proper screening and care.
A specific gene variation appears to significantly increase the risk of developing hepatocellular carcinoma (HCC) in patients with cirrhosis. Researchers found that elevated EGF levels and activation of the EGFR receptor were associated with a higher risk of HCC in patients with at least one copy of the G allele.
Researchers found a connection between TRAIL's receptor and cancer susceptibility, as well as inflammation and cancer via TRAIL. Mouse models with TRAIL receptor knock-out developed larger tumors after exposure to carcinogens or radiation.
Researchers warn that powerful molecular tools in cancer research can lead to misleading conclusions due to the complexity of generated data. The team highlights the need for better understanding of the challenges in analyzing these genomic and proteomic technologies.
A study by Indiana University researchers found that receiving primary care during cancer treatment improves cancer survival rates, especially in lung cancer patients. Primary care utilization increased median survival rates by over fourfold, highlighting the importance of comprehensive care for whole-person health.
Breast cancer patients who received tamoxifen or chemotherapy had a reduced risk of developing a second cancer in the other breast. Chemotherapy was associated with a 43% risk reduction, lasting up to 10 years, while tamoxifen use resulted in a 34% risk reduction that persisted for five years.
Cancer risk increases with age, yet elderly nursing home residents receive relatively few cancer care services. According to a recent study, only 28% of patients with late-stage cancer received hospice care, highlighting the need for further investigation into cancer care in this population.
Researchers at the University of Texas M. D. Anderson Cancer Center have developed a new scoring system that identifies Myelodysplastic Syndrome (MDS) patients with low-risk disease but poor prospects of survival. The system, applied to 856 patients treated between 1976 and 2005, found that older age, low platelet counts, anemia, and p...
The Medical College of Georgia has been designated as a Minority-Based Community Clinical Oncology Program by the National Cancer Institute, receiving a five-year $2.3 million grant to expand access to latest cancer treatment and prevention strategies for minority patients.
A new study found that outcomes of high-risk cancer operations in 80-year-olds are considerably worse than reported, with higher mortality rates and lower survival rates. This limited information may lead to unrealistic expectations about the safety of these operations in the elderly.
The study analyzed data from a national cancer registry and found that type of treatment, sex, race, and insurance status are significantly associated with survival rates among patients with advanced laryngeal cancer. Total laryngectomy was found to be the most effective treatment in increasing survival likelihood.
A new robotic surgery technique called transoral robotic surgery (TORS) has been shown to be effective in removing tonsil cancer with minimal complications and improved patient outcomes. In a study of 27 patients, surgeons successfully removed all cancerous tissues in 93% of cases, with an average surgery time of one hour and 43 minutes.
Researchers found that grade 2 and 3 tumors are more common in HER2+ and triple negative cancers, which have a higher risk of growth and relapse. Cancer came back frequently in these subtypes, with a death rate higher in triple negative breast cancer.
The ATAC trial confirms anastrozole's superior efficacy over tamoxifen, with increased disease-free survival and reduced cancer recurrence. Long-term benefits of anastrozole treatment persist even after completion.
A recent study found that postmenopausal women taking anastrozole after tamoxifen treatment had a 38% reduced risk of breast cancer recurrence. Additionally, research indicates that blood transfusions may slightly increase cancer risk in the months following the procedure, likely due to underlying undiagnosed cancer.
A new test, called RAPID, has been developed to identify proteins that drive cancer growth in acute myeloid leukemia. This breakthrough technology enables researchers to quickly compile a database of mutant genes and potentially match targeted drugs with patients.
A study found that Medicare beneficiaries are not receiving adequate colorectal cancer screening, with only 25% meeting guidelines. The investigation highlights the need for continued efforts to promote screening and reduce mortality from this common disease.
A study found that depression screening in cancer patients is inadequate, with only half of veterans with lung cancer receiving screening. Lung cancer has a high association with depression, and early detection can improve quality of life during treatment. Clinicians need to prioritize depression screening even for end-stage cancer cases.
A study found that many cancer patients with metastatic disease incorrectly believe opioids are only for dying patients. Morphine can improve pain management and quality of life for living patients. Experts stress the importance of professional confidence in opioid use to change these beliefs.
A new study found that immigrant patients in the US are less likely to report a family history of cancer, which may impact access to cancer prevention and screening services. The study's findings suggest that immigrants' cultural norms and communication barriers may inhibit reporting of family health histories.
Researchers announced new data showing Gleevec improves outcomes for children with Ph+ ALL, reversing the poor prognosis, and prevents disease progression in adults with CML. Continuous treatment with Gleevec has shown a declining rate of relapse over time, with no patients progressing to advanced phase in CML.
Abnormal stem cells with deletions of chromosome 7 or duplications of chromosome 8 have been found in some CML patients, suggesting new targets for therapy. The discovery opens a new window into understanding the roots of chronic myeloid leukemia.
Researchers at M.D. Anderson Cancer Center link diet and gardening to lung cancer risk reduction, finding that smokers and nonsmokers can reduce their risk by eating four or more servings of green salad a week and working in the garden once or twice a week.
Researchers found that diets rich in raw vegetables can prevent or slow the growth of some common cancers. Black raspberries may protect against esophageal cancer by reducing oxidative stress, while broccoli sprouts inhibit bladder cancer development through the delivery of cancer prevention agents.
In a study of 79 women with breast cancer, breast MRI revealed important diagnostic information altering treatment plans in 20 percent of cases. The imaging modality detected additional cancers, discovered cancer in the opposite breast, or determined tumors were larger than expected.
Researchers at UCLA used Atomic Force Microscopy to measure the softness of living cancer cells from patient samples, distinguishing them from normal cells. This method may aid in diagnosing cancer and personalizing treatments.
A new study finds that cancer patients are willing and able to self-report symptoms using the Internet, providing key data in real time to healthcare providers. This can fill gaps in clinicians' knowledge and improve patient safety and quality of care.
Researchers present findings on how poverty affects cancer prognosis, ethnicity influences medical care, and genetics impact survival rates among different groups of women. A study reveals African-American women face poorer disease-free survival rates due to racial-specific biology, prompting a reevaluation of screening guidelines. Mea...
A systematic review of recent studies suggests PET imaging can accurately diagnose and stage lung cancer, even in early stages. The imaging modality is found to be more accurate than CT imaging for treatment decisions in non–small-cell lung cancer patients.