Articles tagged with Cancer Patients
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Researchers at UCLA's Jonsson Cancer Center have discovered biomarkers that can help personalize treatment for patients with advanced non-small cell lung cancer. These biomarkers may identify patients who will respond to the Celebrex and Tarceva combination therapy, sparing them from ineffective treatments.
Gas6 protein has proven successful in treating mice with anemia without causing side effects, while reinforcing EPO's effect. This could form the basis for a new treatment for patients where EPO is ineffective.
Researchers analyzed data from nearly 30,000 women with breast cancer and found that female surgeons were more likely to prescribe post-surgical radiation therapy. Women who received radiation had a surgeon trained in the US or with an M.D. degree compared to a D.O. degree.
A new study found significant racial and ethnic differences in the treatment and survival of patients with extremity soft-tissue sarcomas. Blacks had lower rates of surgeries that would have saved their arm or leg, higher death rates, and were least likely to receive additional treatments for improved survival.
A recent study by Beth Israel Deaconess Medical Center found that the majority of adverse events and device malfunctions associated with biliary stents occur during off-label use. Over 1 million patients received these devices for 'off-label' treatments between 2003 and 2006.
A systematic review found sorafenib significantly increases the risk of developing hypertension, particularly high-grade hypertension. Patients receiving sorafenib require close monitoring and effective management to prevent cardiovascular complications.
Research finds gastric cancer patients post-gastrectomy have high prevalence of osteoporosis (38.3%) and vertebral deformities. Screening by Dual-energy X-ray absorptiometry is recommended for those over 60 or with anemia/back pain.
A study found that two microRNAs, miR-191 and miR-199a, are associated with patient survival in high-risk acute-leukemia patients. These molecules may serve as targets for future therapies, offering hope for patients with limited treatment options.
A study published in Clinical Cancer Research demonstrates that a novel mass-spectrometry based proteomic profiling method is more accurate than traditional biomarkers in distinguishing liver cancer patients from patients with hepatitis C liver cirrhosis. The technique, SELDI-TOF MS, identified an 11-protein signature that accurately d...
A new study found that racial disparities in cancer care have persisted despite efforts to mitigate them. Black patients are significantly less likely than white patients to receive therapy for certain types of cancer, including lung, breast, colon, and prostate cancer.
A recent study by Yale researchers found significant racial disparities in cancer therapy, with black patients less likely than white counterparts to receive treatment for various cancers. Despite efforts to improve access to care, the disparities persisted, highlighting the need for continued work to address these issues.
Research identifies variations in cancer, enabling more precise treatment; childhood cancer experience differs from adults, with teens facing stigma and discrimination.
Researchers found a founder mutation in two large US families that may contribute to significant colon cancer cases. The mutation increases risk by 2-3 times by age 80, but can be prevented with proper screening and care.
A specific gene variation appears to significantly increase the risk of developing hepatocellular carcinoma (HCC) in patients with cirrhosis. Researchers found that elevated EGF levels and activation of the EGFR receptor were associated with a higher risk of HCC in patients with at least one copy of the G allele.
Researchers found a connection between TRAIL's receptor and cancer susceptibility, as well as inflammation and cancer via TRAIL. Mouse models with TRAIL receptor knock-out developed larger tumors after exposure to carcinogens or radiation.
Researchers warn that powerful molecular tools in cancer research can lead to misleading conclusions due to the complexity of generated data. The team highlights the need for better understanding of the challenges in analyzing these genomic and proteomic technologies.
A study by Indiana University researchers found that receiving primary care during cancer treatment improves cancer survival rates, especially in lung cancer patients. Primary care utilization increased median survival rates by over fourfold, highlighting the importance of comprehensive care for whole-person health.
Breast cancer patients who received tamoxifen or chemotherapy had a reduced risk of developing a second cancer in the other breast. Chemotherapy was associated with a 43% risk reduction, lasting up to 10 years, while tamoxifen use resulted in a 34% risk reduction that persisted for five years.
Cancer risk increases with age, yet elderly nursing home residents receive relatively few cancer care services. According to a recent study, only 28% of patients with late-stage cancer received hospice care, highlighting the need for further investigation into cancer care in this population.
Researchers at the University of Texas M. D. Anderson Cancer Center have developed a new scoring system that identifies Myelodysplastic Syndrome (MDS) patients with low-risk disease but poor prospects of survival. The system, applied to 856 patients treated between 1976 and 2005, found that older age, low platelet counts, anemia, and p...
The Medical College of Georgia has been designated as a Minority-Based Community Clinical Oncology Program by the National Cancer Institute, receiving a five-year $2.3 million grant to expand access to latest cancer treatment and prevention strategies for minority patients.
A new study found that outcomes of high-risk cancer operations in 80-year-olds are considerably worse than reported, with higher mortality rates and lower survival rates. This limited information may lead to unrealistic expectations about the safety of these operations in the elderly.
The study analyzed data from a national cancer registry and found that type of treatment, sex, race, and insurance status are significantly associated with survival rates among patients with advanced laryngeal cancer. Total laryngectomy was found to be the most effective treatment in increasing survival likelihood.
A new robotic surgery technique called transoral robotic surgery (TORS) has been shown to be effective in removing tonsil cancer with minimal complications and improved patient outcomes. In a study of 27 patients, surgeons successfully removed all cancerous tissues in 93% of cases, with an average surgery time of one hour and 43 minutes.
Researchers found that grade 2 and 3 tumors are more common in HER2+ and triple negative cancers, which have a higher risk of growth and relapse. Cancer came back frequently in these subtypes, with a death rate higher in triple negative breast cancer.
The ATAC trial confirms anastrozole's superior efficacy over tamoxifen, with increased disease-free survival and reduced cancer recurrence. Long-term benefits of anastrozole treatment persist even after completion.
A recent study found that postmenopausal women taking anastrozole after tamoxifen treatment had a 38% reduced risk of breast cancer recurrence. Additionally, research indicates that blood transfusions may slightly increase cancer risk in the months following the procedure, likely due to underlying undiagnosed cancer.
A new test, called RAPID, has been developed to identify proteins that drive cancer growth in acute myeloid leukemia. This breakthrough technology enables researchers to quickly compile a database of mutant genes and potentially match targeted drugs with patients.
A study found that Medicare beneficiaries are not receiving adequate colorectal cancer screening, with only 25% meeting guidelines. The investigation highlights the need for continued efforts to promote screening and reduce mortality from this common disease.
A study found that depression screening in cancer patients is inadequate, with only half of veterans with lung cancer receiving screening. Lung cancer has a high association with depression, and early detection can improve quality of life during treatment. Clinicians need to prioritize depression screening even for end-stage cancer cases.
A study found that many cancer patients with metastatic disease incorrectly believe opioids are only for dying patients. Morphine can improve pain management and quality of life for living patients. Experts stress the importance of professional confidence in opioid use to change these beliefs.
A new study found that immigrant patients in the US are less likely to report a family history of cancer, which may impact access to cancer prevention and screening services. The study's findings suggest that immigrants' cultural norms and communication barriers may inhibit reporting of family health histories.
Researchers announced new data showing Gleevec improves outcomes for children with Ph+ ALL, reversing the poor prognosis, and prevents disease progression in adults with CML. Continuous treatment with Gleevec has shown a declining rate of relapse over time, with no patients progressing to advanced phase in CML.
Abnormal stem cells with deletions of chromosome 7 or duplications of chromosome 8 have been found in some CML patients, suggesting new targets for therapy. The discovery opens a new window into understanding the roots of chronic myeloid leukemia.
Researchers at M.D. Anderson Cancer Center link diet and gardening to lung cancer risk reduction, finding that smokers and nonsmokers can reduce their risk by eating four or more servings of green salad a week and working in the garden once or twice a week.
Researchers found that diets rich in raw vegetables can prevent or slow the growth of some common cancers. Black raspberries may protect against esophageal cancer by reducing oxidative stress, while broccoli sprouts inhibit bladder cancer development through the delivery of cancer prevention agents.
In a study of 79 women with breast cancer, breast MRI revealed important diagnostic information altering treatment plans in 20 percent of cases. The imaging modality detected additional cancers, discovered cancer in the opposite breast, or determined tumors were larger than expected.
Researchers at UCLA used Atomic Force Microscopy to measure the softness of living cancer cells from patient samples, distinguishing them from normal cells. This method may aid in diagnosing cancer and personalizing treatments.
A new study finds that cancer patients are willing and able to self-report symptoms using the Internet, providing key data in real time to healthcare providers. This can fill gaps in clinicians' knowledge and improve patient safety and quality of care.
Researchers present findings on how poverty affects cancer prognosis, ethnicity influences medical care, and genetics impact survival rates among different groups of women. A study reveals African-American women face poorer disease-free survival rates due to racial-specific biology, prompting a reevaluation of screening guidelines. Mea...
A systematic review of recent studies suggests PET imaging can accurately diagnose and stage lung cancer, even in early stages. The imaging modality is found to be more accurate than CT imaging for treatment decisions in non–small-cell lung cancer patients.
A Mayo Clinic study shows cryoablation can provide durable pain relief for patients with bone metastases. Eighty percent of patients experienced significant pain reduction after the treatment, which also improved their quality of life.
The Institute of Genetics and Molecular Medicine (IGMM) brings together researchers in human biology to develop non-toxic cancer treatments that could prevent tumours from spreading. The institute aims to learn lessons from each condition to inform others and develop personalized medical treatment.
A study found that many prostate cancer patients receive treatment contraindicated by pre-existing conditions, such as urinary or bowel dysfunction. This 'mismatched' therapy can lead to worsened symptoms and outcomes.
A study found that over 89% of men with early prostate cancer received inappropriate therapies due to pre-existing problems. The mismatched treatments may be attributed to patients' reluctance to discuss symptoms with their physicians.
A review of 62 Mayo Clinic patients who underwent cryoablation to treat cancerous kidney tumors found that all patients remained cancer-free for up to two and a half years after the procedure. The treatment's effectiveness was demonstrated by the successful elimination of 89 out of 91 tumors in a single treatment session.
Researchers found unprecedented survival for patients with multiple myeloma when treated with lenalidomide and dexamethasone, achieving a median survival of nearly three years. The study shows promise for early treatment and has changed official guidelines to add REVLIMID as an initial treatment.
A study found a 150% increase in women choosing contralateral prophylactic mastectomy when cancer is confined to one breast. Despite this, researchers caution that the procedure may not improve overall survival and raise concerns about unnecessary invasive treatment.
A structured support program improved prostate cancer patients' and their spouses' lives by addressing symptom management, hope, and couples' communication. The intervention also reduced mental health distress and increased physical quality of life.
A new study from the University of Michigan Comprehensive Cancer Center shows that targeted interventions for caregivers can significantly improve their physical and emotional quality of life. The FOCUS Program, a family-based intervention, provided benefits for spouses of prostate cancer patients, including reduced uncertainty and imp...
A rare hereditary disorder, Li-Fraumeni syndrome, has been identified in an Asian female with early onset breast cancer. Genetic testing may help diagnose LFS in young women with a family history of the condition, which increases the risk of developing multiple primary tumors.
BioDelivery Sciences International has submitted its New Drug Application for BEMA Fentanyl, a treatment for breakthrough cancer pain, to the FDA. The application is based on positive results from clinical trials, including a Phase III efficacy trial that demonstrated significant pain reduction and low discontinuation rates.
A study of over 11,000 men found that those receiving radiation seed implants had a significant reduction in mortality risk compared to those on watchful waiting/active surveillance within six months of diagnosis. Brachytherapy was shown to be as effective as radical prostatectomy and surgery in extending life expectancy.
Men with low-risk prostate cancer who miss two or more radiation treatments in an eight-week course face a higher chance of their cancer recurring. The study of nearly 1,800 patients found that controlling cancer within the prostate and preventing its spread outside makes the greatest difference for these patients.
The Seneca Valley Virus shows promise as a treatment for some metastatic cancers. Cervical cancer survivors are at greater risk of second cancers due to radiation exposure. A novel trial design identifies promising treatments in clinical trials.
An international panel of researchers developed guidelines to prevent and treat venous thromboembolism, a deadly complication of cancer. The new guidelines recommend the use of anticoagulants in hospitalized cancer patients and suggest treating blood clots for at least six months afterwards.
Researchers are investigating vinflunine as a potential treatment for advanced bladder cancer patients who cannot receive standard cisplatin and gemcitabine chemotherapy due to kidney problems. The Phase II study aims to determine if vinflunine can effectively treat the disease while minimizing side effects.
A study found that nearly a quarter of cancer patients receiving radiation therapy are not getting vaccinated against flu and pneumonia, posing a significant risk to their health. Oncologists can play a key role in informing patients about recommended vaccines during regular interactions.
OHSU researchers found that combining surgery and radiation therapy increases early survival rates in patients with locoregional extrahepatic cholangiocarcinoma. The study analyzed 2,591 cases of bile duct cancer diagnosed between 1973 and 1998.
A study found that nearly two-thirds of low-income and minority cancer patients accepted patient navigator assistance to reduce barriers to care. LPNs helped patients access clinical trials, resulting in faster timeframes for reducing barriers to treatment.