Articles tagged with Cancer Patients
A Mayo Clinic study shows cryoablation can provide durable pain relief for patients with bone metastases. Eighty percent of patients experienced significant pain reduction after the treatment, which also improved their quality of life.
The Institute of Genetics and Molecular Medicine (IGMM) brings together researchers in human biology to develop non-toxic cancer treatments that could prevent tumours from spreading. The institute aims to learn lessons from each condition to inform others and develop personalized medical treatment.
A study found that many prostate cancer patients receive treatment contraindicated by pre-existing conditions, such as urinary or bowel dysfunction. This 'mismatched' therapy can lead to worsened symptoms and outcomes.
A study found that over 89% of men with early prostate cancer received inappropriate therapies due to pre-existing problems. The mismatched treatments may be attributed to patients' reluctance to discuss symptoms with their physicians.
A review of 62 Mayo Clinic patients who underwent cryoablation to treat cancerous kidney tumors found that all patients remained cancer-free for up to two and a half years after the procedure. The treatment's effectiveness was demonstrated by the successful elimination of 89 out of 91 tumors in a single treatment session.
Researchers found unprecedented survival for patients with multiple myeloma when treated with lenalidomide and dexamethasone, achieving a median survival of nearly three years. The study shows promise for early treatment and has changed official guidelines to add REVLIMID as an initial treatment.
A study found a 150% increase in women choosing contralateral prophylactic mastectomy when cancer is confined to one breast. Despite this, researchers caution that the procedure may not improve overall survival and raise concerns about unnecessary invasive treatment.
A structured support program improved prostate cancer patients' and their spouses' lives by addressing symptom management, hope, and couples' communication. The intervention also reduced mental health distress and increased physical quality of life.
A new study from the University of Michigan Comprehensive Cancer Center shows that targeted interventions for caregivers can significantly improve their physical and emotional quality of life. The FOCUS Program, a family-based intervention, provided benefits for spouses of prostate cancer patients, including reduced uncertainty and imp...
A rare hereditary disorder, Li-Fraumeni syndrome, has been identified in an Asian female with early onset breast cancer. Genetic testing may help diagnose LFS in young women with a family history of the condition, which increases the risk of developing multiple primary tumors.
BioDelivery Sciences International has submitted its New Drug Application for BEMA Fentanyl, a treatment for breakthrough cancer pain, to the FDA. The application is based on positive results from clinical trials, including a Phase III efficacy trial that demonstrated significant pain reduction and low discontinuation rates.
A study of over 11,000 men found that those receiving radiation seed implants had a significant reduction in mortality risk compared to those on watchful waiting/active surveillance within six months of diagnosis. Brachytherapy was shown to be as effective as radical prostatectomy and surgery in extending life expectancy.
Men with low-risk prostate cancer who miss two or more radiation treatments in an eight-week course face a higher chance of their cancer recurring. The study of nearly 1,800 patients found that controlling cancer within the prostate and preventing its spread outside makes the greatest difference for these patients.
The Seneca Valley Virus shows promise as a treatment for some metastatic cancers. Cervical cancer survivors are at greater risk of second cancers due to radiation exposure. A novel trial design identifies promising treatments in clinical trials.
An international panel of researchers developed guidelines to prevent and treat venous thromboembolism, a deadly complication of cancer. The new guidelines recommend the use of anticoagulants in hospitalized cancer patients and suggest treating blood clots for at least six months afterwards.
Researchers are investigating vinflunine as a potential treatment for advanced bladder cancer patients who cannot receive standard cisplatin and gemcitabine chemotherapy due to kidney problems. The Phase II study aims to determine if vinflunine can effectively treat the disease while minimizing side effects.
A study found that nearly a quarter of cancer patients receiving radiation therapy are not getting vaccinated against flu and pneumonia, posing a significant risk to their health. Oncologists can play a key role in informing patients about recommended vaccines during regular interactions.
OHSU researchers found that combining surgery and radiation therapy increases early survival rates in patients with locoregional extrahepatic cholangiocarcinoma. The study analyzed 2,591 cases of bile duct cancer diagnosed between 1973 and 1998.
A study found that nearly two-thirds of low-income and minority cancer patients accepted patient navigator assistance to reduce barriers to care. LPNs helped patients access clinical trials, resulting in faster timeframes for reducing barriers to treatment.
Researchers at Oregon Health & Science University found that positioning pelvic cancer patients on their stomachs rather than their backs improves the delivery of radiation therapy, reducing toxicity and improving precision. This method allows for more accurate targeting of tumors while sparing healthy tissues.
Demand for Spanish-language cancer web materials has quadrupled, with OncoLink en español seeing a significant increase in unique visitors. However, limited internet access and different search patterns among Spanish-speaking users highlight the need for tailored content to meet their needs.
An education program for African-Americans showed significant improvement in cancer knowledge and attitudes, with 36% of participants demonstrating better understanding after four months. Younger participants showed greater improvement than older adults, highlighting the crucial role of education in addressing cancer disparities.
A new integrated approach to intensity-modulated radiation therapy (IMRT) has been shown to provide high-quality care for head and neck cancer patients in community centers. The study found no significant differences in treatment outcomes or survival rates between academic and community centers.
In a Phase I/II clinical trial, ECO-4601 demonstrated safety and efficacy in treating advanced solid tumors. The drug targets the RAS/MAPK signaling pathway and peripheral benzodiazepine receptor, offering a unique mechanism of action.
A systematic review found that 44% of activity-based trials and 50% of psychological studies reported significant results in reducing fatigue among cancer patients. However, the effects were considered modest, and more research is needed to determine their effectiveness.
Researchers found that quantitative index adds accurate information about patients' responses to first-line chemotherapy, improving tumor response prediction. This method can also identify disease transformation and shorten treatment for favorable responders.
GSK923295A, a first-in-class targeted therapy, demonstrates broad activity and potential for enhanced tolerability in preclinical studies. The experimental drug inhibits the mitotic kinesin CENP-E, leading to apoptosis and misaligned chromosomes in cancer cells.
A study by University of Pennsylvania researchers found that emotional well-being has no influence on cancer survival, contrary to long-held beliefs. The study examined 1,093 patients with head and neck cancers and found no correlation between emotional status and overall survival.
A large-scale study published in CANCER journal found that a patient's emotional state has no direct or indirect effect on cancer survival or disease progression. The research analyzed data from over 1,000 patients with head and neck cancer, concluding that psychological factors are not independently prognostic in cancer management.
The Institute of Medicine report outlines an action plan to ensure that cancer patients receive necessary psychosocial health services. Key findings include the need to address psychological and social side effects, increasing patient suffering and treatment adherence.
A new study provides insight into trastuzumab resistance in breast cancer by identifying the PI3K pathway as a key factor. The research found that tumor suppressor PTEN and activating mutations of the PIK3CA gene contribute to trastuzumab resistance, suggesting a potential strategy for treating resistant patients.
Dr. Gregory J. Hannon is a recipient of the Memorial Sloan-Kettering Cancer Center's 2007 Paul Marks Prize for Cancer Research. His work on RNA interference has led to significant contributions in understanding and treating cancer.
A study published in Journal of the National Cancer Institute found that androgen deprivation therapy used to treat localized prostate cancer increases the risk of death from heart disease. The therapy can lead to metabolic syndrome, which raises the risk of type II diabetes or coronary artery disease.
A study of 1,421 cancer patients found no difference in treatment location or wait times between pre- and post-Medicare reimbursement cuts. Patient satisfaction with care remained high, with similar levels of satisfaction reported by patients treated before and after the changes.
Penn researchers have found a new way Kaposi's Sarcoma-associated Herpes Virus (KSHV) causes cancer by interfering with the degradation of a crucial signaling molecule called Notch. This finding sheds light on how KSHV subverts normal cell growth, potentially leading to new treatments for viral-associated cancers.
A study aims to identify genetic variations associated with radiotherapy side effects, enabling individualized treatment. The research hopes to reduce toxicity while maintaining tumour control.
A new survey reveals that 14-45% of cancer patients suffer from severe cognitive deficits, leading to a 'loss of self' and significant problems at home and in the workplace. The study also found that doctors are often dismissive or indifferent to patients' concerns.
Researchers found that patients with large polyps or adenomas may need more frequent follow-up, while those with only a few small polyps can be screened less often. Relatives of patients with large polyps should also be targeted for screening.
A study of 215 cancer patients found that acupuncture did not reduce nausea caused by radiotherapy, but patients believed it helped. The treatment had no statistically significant effect on nausea duration or intensity.
A new study suggests that an ultrasound-guided fine needle biopsy technique can accurately detect cancer in lymph nodes with a false positive rate of only one percent. The method has been shown to be highly accurate and may reduce the need for unnecessary sentinel node operations.
A new study has found that adolescents may suffer from severe post-traumatic stress symptoms when a parent is recently diagnosed with cancer. Parents tend to underestimate the problems, and healthcare professionals should be aware of the prevalence of PTSS in children of a parent with cancer.
In a surprising study, married esophageal cancer patients reported worsening physical wellbeing and increasing pain frequency over time. However, they showed less improvement in their legal worries compared to single patients.
A randomized trial found that vaginal brachytherapy significantly improves quality of life for women with endometrial cancer, reducing bowel symptoms and fatigue. Quality of life scores were higher in the brachytherapy group after six months, but did not differ at initial surgery.
Researchers found that personalized behavioral intervention services significantly improved colorectal cancer screening rates in primary care practices. The tailored interventions resulted in increased screenings among patients who were not up-to-date with guidelines, with rates reaching as high as 48%.
The increasing elderly population will pose significant challenges in cancer care, including inadequate training of healthcare professionals and inappropriate ageist attitudes. Improved technology may help address some issues, but a digital divide and escalating costs threaten the accessibility of cancer treatment.
A new study from the University of Michigan Comprehensive Cancer Center finds that cancer patients and their spouses experience similar physical and emotional quality of life. The study, which analyzed data from 263 men with prostate cancer and their spouses, found significant differences in quality of life based on the phase of illness.
Effective communication is essential for good cancer care, according to a new report by the National Cancer Institute. The report highlights the need for patients to have access to clear information about their treatment options and outcomes, as well as the importance of patient-centered communication in managing uncertainty and anxiety.
A new study used gene chip data to improve treatment outcomes for patients with advanced, incurable cancer. Four out of seven patients showed a better response than expected when their tumor's gene expression was analyzed and used to guide treatment.
Researchers at Memorial Sloan-Kettering Cancer Center have developed a new therapy using re-engineered human T cells that can recognize and kill cancerous B cells. The treatment showed promising results in mice, eradicating cancer in 44% of those with human ALL tumors.
A long-term study found that stem cell transplant patients experience decreased sexual function and activity, particularly in females. While males recover partially over time, females remain compromised. The study suggests systemic therapies and chronic graft-versus-host disease contribute to sexual dysfunction.
Researchers developed an acoustic sensor that can detect small amounts of mesothelin, a biomarker associated with several cancers. The device uses electrodes and antibodies to identify changes in frequency caused by the presence of mesothelin.
A pilot study found that patients with head and neck cancer exhibited inferior performance in some driving skills, including longer brake reaction times and greater steering variability. However, there was no significant difference in average speed or total collisions between the patient group and community control group.
Researchers found that cervical tumors with high glucose uptake (SUV) on PET scans had higher recurrence rates, persistent disease, and lower survival rates. The study suggests that SUV is a more sensitive indicator of tumor aggressiveness than standard staging protocols.
The Oregon Health & Science University School of Medicine is part of a national team researching ways to preserve or restore fertility in women with cancer. Researchers are studying methods to freeze and store ovary tissue and grow follicles in culture, aiming to help young cancer patients have children.
Emory researchers identify Ribosomal S6 kinase 2 (RSK2) as a critical downstream signaling protein effector of FGFR3 in myeloma cells. RSK2 plays a key role in regulating cell cycle and survival, and targeting it with drugs may be effective in treating multiple myeloma.
Researchers will present novel findings on personalized medicine, including new biomarkers for early detection, advanced imaging technologies, and proteomics applications. Key advances include a blood test for liver cancer and a protein target for lung cancer diagnosis.
Studies show that up to 50% of patients with advanced cancer suffer from major psychiatric disorders, including adjustment disorders, anxiety disorders, and depressive disorders. Effective communication, emotional support, and screening can help manage these conditions, reducing psychological distress and improving quality of life.
A new study finds breast cancer survivors who received both chemotherapy and radiotherapy reported the most severe and prolonged fatigue. The study, published in CANCER, a peer-reviewed journal of the American Cancer Society, found women who received both treatments experienced more days with reported fatigue at each assessment.
The Oncofertility Consortium seeks to alter the medical world's approach to female cancer patients, promoting a new consciousness to protect their reproductive health. Researchers will investigate fertility threats posed by cancer treatment and develop strategies to improve communication with newly diagnosed patients.
Researchers at Johns Hopkins Kimmel Cancer Center have identified a genetic signature associated with aggressive melanomas. The study found that certain genes are linked to an aggressive profile, which could be used to predict patient outcomes and develop tailored therapies.