Articles tagged with Cancer Patients
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Researchers at Oregon Health & Science University found that positioning pelvic cancer patients on their stomachs rather than their backs improves the delivery of radiation therapy, reducing toxicity and improving precision. This method allows for more accurate targeting of tumors while sparing healthy tissues.
Demand for Spanish-language cancer web materials has quadrupled, with OncoLink en español seeing a significant increase in unique visitors. However, limited internet access and different search patterns among Spanish-speaking users highlight the need for tailored content to meet their needs.
An education program for African-Americans showed significant improvement in cancer knowledge and attitudes, with 36% of participants demonstrating better understanding after four months. Younger participants showed greater improvement than older adults, highlighting the crucial role of education in addressing cancer disparities.
A new integrated approach to intensity-modulated radiation therapy (IMRT) has been shown to provide high-quality care for head and neck cancer patients in community centers. The study found no significant differences in treatment outcomes or survival rates between academic and community centers.
In a Phase I/II clinical trial, ECO-4601 demonstrated safety and efficacy in treating advanced solid tumors. The drug targets the RAS/MAPK signaling pathway and peripheral benzodiazepine receptor, offering a unique mechanism of action.
A systematic review found that 44% of activity-based trials and 50% of psychological studies reported significant results in reducing fatigue among cancer patients. However, the effects were considered modest, and more research is needed to determine their effectiveness.
Researchers found that quantitative index adds accurate information about patients' responses to first-line chemotherapy, improving tumor response prediction. This method can also identify disease transformation and shorten treatment for favorable responders.
GSK923295A, a first-in-class targeted therapy, demonstrates broad activity and potential for enhanced tolerability in preclinical studies. The experimental drug inhibits the mitotic kinesin CENP-E, leading to apoptosis and misaligned chromosomes in cancer cells.
A study by University of Pennsylvania researchers found that emotional well-being has no influence on cancer survival, contrary to long-held beliefs. The study examined 1,093 patients with head and neck cancers and found no correlation between emotional status and overall survival.
A large-scale study published in CANCER journal found that a patient's emotional state has no direct or indirect effect on cancer survival or disease progression. The research analyzed data from over 1,000 patients with head and neck cancer, concluding that psychological factors are not independently prognostic in cancer management.
The Institute of Medicine report outlines an action plan to ensure that cancer patients receive necessary psychosocial health services. Key findings include the need to address psychological and social side effects, increasing patient suffering and treatment adherence.
A new study provides insight into trastuzumab resistance in breast cancer by identifying the PI3K pathway as a key factor. The research found that tumor suppressor PTEN and activating mutations of the PIK3CA gene contribute to trastuzumab resistance, suggesting a potential strategy for treating resistant patients.
Dr. Gregory J. Hannon is a recipient of the Memorial Sloan-Kettering Cancer Center's 2007 Paul Marks Prize for Cancer Research. His work on RNA interference has led to significant contributions in understanding and treating cancer.
A study published in Journal of the National Cancer Institute found that androgen deprivation therapy used to treat localized prostate cancer increases the risk of death from heart disease. The therapy can lead to metabolic syndrome, which raises the risk of type II diabetes or coronary artery disease.
A study of 1,421 cancer patients found no difference in treatment location or wait times between pre- and post-Medicare reimbursement cuts. Patient satisfaction with care remained high, with similar levels of satisfaction reported by patients treated before and after the changes.
Penn researchers have found a new way Kaposi's Sarcoma-associated Herpes Virus (KSHV) causes cancer by interfering with the degradation of a crucial signaling molecule called Notch. This finding sheds light on how KSHV subverts normal cell growth, potentially leading to new treatments for viral-associated cancers.
A study aims to identify genetic variations associated with radiotherapy side effects, enabling individualized treatment. The research hopes to reduce toxicity while maintaining tumour control.
A new survey reveals that 14-45% of cancer patients suffer from severe cognitive deficits, leading to a 'loss of self' and significant problems at home and in the workplace. The study also found that doctors are often dismissive or indifferent to patients' concerns.
Researchers found that patients with large polyps or adenomas may need more frequent follow-up, while those with only a few small polyps can be screened less often. Relatives of patients with large polyps should also be targeted for screening.
A study of 215 cancer patients found that acupuncture did not reduce nausea caused by radiotherapy, but patients believed it helped. The treatment had no statistically significant effect on nausea duration or intensity.
A new study suggests that an ultrasound-guided fine needle biopsy technique can accurately detect cancer in lymph nodes with a false positive rate of only one percent. The method has been shown to be highly accurate and may reduce the need for unnecessary sentinel node operations.
A new study has found that adolescents may suffer from severe post-traumatic stress symptoms when a parent is recently diagnosed with cancer. Parents tend to underestimate the problems, and healthcare professionals should be aware of the prevalence of PTSS in children of a parent with cancer.
In a surprising study, married esophageal cancer patients reported worsening physical wellbeing and increasing pain frequency over time. However, they showed less improvement in their legal worries compared to single patients.
A randomized trial found that vaginal brachytherapy significantly improves quality of life for women with endometrial cancer, reducing bowel symptoms and fatigue. Quality of life scores were higher in the brachytherapy group after six months, but did not differ at initial surgery.
Researchers found that personalized behavioral intervention services significantly improved colorectal cancer screening rates in primary care practices. The tailored interventions resulted in increased screenings among patients who were not up-to-date with guidelines, with rates reaching as high as 48%.
The increasing elderly population will pose significant challenges in cancer care, including inadequate training of healthcare professionals and inappropriate ageist attitudes. Improved technology may help address some issues, but a digital divide and escalating costs threaten the accessibility of cancer treatment.
A new study from the University of Michigan Comprehensive Cancer Center finds that cancer patients and their spouses experience similar physical and emotional quality of life. The study, which analyzed data from 263 men with prostate cancer and their spouses, found significant differences in quality of life based on the phase of illness.
Effective communication is essential for good cancer care, according to a new report by the National Cancer Institute. The report highlights the need for patients to have access to clear information about their treatment options and outcomes, as well as the importance of patient-centered communication in managing uncertainty and anxiety.
A new study used gene chip data to improve treatment outcomes for patients with advanced, incurable cancer. Four out of seven patients showed a better response than expected when their tumor's gene expression was analyzed and used to guide treatment.
Researchers at Memorial Sloan-Kettering Cancer Center have developed a new therapy using re-engineered human T cells that can recognize and kill cancerous B cells. The treatment showed promising results in mice, eradicating cancer in 44% of those with human ALL tumors.
A long-term study found that stem cell transplant patients experience decreased sexual function and activity, particularly in females. While males recover partially over time, females remain compromised. The study suggests systemic therapies and chronic graft-versus-host disease contribute to sexual dysfunction.
Researchers developed an acoustic sensor that can detect small amounts of mesothelin, a biomarker associated with several cancers. The device uses electrodes and antibodies to identify changes in frequency caused by the presence of mesothelin.
A pilot study found that patients with head and neck cancer exhibited inferior performance in some driving skills, including longer brake reaction times and greater steering variability. However, there was no significant difference in average speed or total collisions between the patient group and community control group.
Researchers found that cervical tumors with high glucose uptake (SUV) on PET scans had higher recurrence rates, persistent disease, and lower survival rates. The study suggests that SUV is a more sensitive indicator of tumor aggressiveness than standard staging protocols.
The Oregon Health & Science University School of Medicine is part of a national team researching ways to preserve or restore fertility in women with cancer. Researchers are studying methods to freeze and store ovary tissue and grow follicles in culture, aiming to help young cancer patients have children.
Emory researchers identify Ribosomal S6 kinase 2 (RSK2) as a critical downstream signaling protein effector of FGFR3 in myeloma cells. RSK2 plays a key role in regulating cell cycle and survival, and targeting it with drugs may be effective in treating multiple myeloma.
Researchers will present novel findings on personalized medicine, including new biomarkers for early detection, advanced imaging technologies, and proteomics applications. Key advances include a blood test for liver cancer and a protein target for lung cancer diagnosis.
Studies show that up to 50% of patients with advanced cancer suffer from major psychiatric disorders, including adjustment disorders, anxiety disorders, and depressive disorders. Effective communication, emotional support, and screening can help manage these conditions, reducing psychological distress and improving quality of life.
A new study finds breast cancer survivors who received both chemotherapy and radiotherapy reported the most severe and prolonged fatigue. The study, published in CANCER, a peer-reviewed journal of the American Cancer Society, found women who received both treatments experienced more days with reported fatigue at each assessment.
The Oncofertility Consortium seeks to alter the medical world's approach to female cancer patients, promoting a new consciousness to protect their reproductive health. Researchers will investigate fertility threats posed by cancer treatment and develop strategies to improve communication with newly diagnosed patients.
Researchers at Johns Hopkins Kimmel Cancer Center have identified a genetic signature associated with aggressive melanomas. The study found that certain genes are linked to an aggressive profile, which could be used to predict patient outcomes and develop tailored therapies.
A leading epidemiologist attacks a Swedish research report on cancer drug access, citing flawed methods, incorrect conclusions, and potential industry influence. The Karolinska report aimed to link national cancer survival rates with access to cancer drugs, but its methodology has been disputed.
A study of 13,001 RA patients reveals that biologic treatment increases the risk of skin cancers, including melanoma, but not other types of cancer. The research suggests that current biologic therapy may be safe for RA patients, providing reassurance for those considering treatment.
Researchers at the University of North Carolina analyzed data from nine studies and found that patients with a specific gene variation had a greater risk of side effects when taking medium or high doses of irinotecan. The study suggests that the FDA should modify its guidelines to reflect this finding.
Researchers find that HSP 90 inhibitors can degrade proteins perpetuating inflammation, restoring lung function and reducing blood vessel leakage in ICU patients. The study suggests a potential new treatment for sepsis using these cancer-fighting compounds.
Patients with Medicaid and those lacking insurance have a higher risk of being diagnosed with advanced-stage laryngeal cancer at diagnosis. This association holds true across various demographic groups, emphasizing the importance of access to healthcare for cancer screening and treatment.
Researchers found that dense breasts and high hormone levels increase breast cancer risk by 400% and 200%, respectively. The study also showed additive effects, where women with both dense breasts and excess hormones face a 600% increased risk.
Researchers identified an unusually high rate of severe allergic reactions to cetuximab among patients living in the middle South, with a 22% rate compared to 2% nationwide. The strongest predictor of a reaction was a history of other hypersensitivities.
Researchers identified a new strategy that KSHV uses to replicate its viral genome, allowing it to evade the immune system. By eliminating viral protein production, they found that KSHV DNA can autonomously recruit cellular replication machinery proteins.
Prophylactic cranial irradiation reduces the risk of symptomatic brain metastases and prolongs survival in small-cell lung cancer patients with extensive disease. The EORTC trial results show a significant increase in one-year survival, from 13.3% to 27.1%, after receiving prophylactic cranial irradiation.
Researchers discovered B7-H3, an immune molecule that predicts prostate cancer progression and recurrence after surgery. The biomarker can help individualize treatment plans for patients.
A study found that patients with a diet high in meat, fat and refined grains had an increased risk of cancer recurrence and death compared to those with a diet rich in fruits and vegetables. The researchers identified two dietary patterns: prudent and Western, and found that the Western pattern was associated with a significant increas...
Researchers found that metformin slows tumor growth in mice with colon cancer lacking the regulatory gene p53. The study's findings may lead to new therapies for aggressive and resistant human cancers.
A recent study reveals radiologists can diagnose clinically unseen venous thromboembolic disease in cancer patients earlier by closely examining CT scans of the thorax, abdomen, and pelvis. The study identified 23 unsuspected iliofemoral DVTs and four common iliac vein involvements among 736 patients.
A recent study published in Immunity reveals that the presence of pro-death proteins Bax and Bak is necessary for healthy immune function, specifically in T-cell cells. The absence of these proteins disrupts calcium signaling pathways, leading to reduced energy production and impaired cell division.
Researchers at Duke University found that high-intensity focused ultrasound can activate the immune system to attack cancer cells, including those that have spread through the bloodstream. The treatment uses mechanical vibration to break apart tumor cells, releasing toxic substances that alert the immune system to cancer threats.
Researchers found that taking vitamins and minerals did not reduce liver cancer death rates in a study conducted by the National Cancer Institute. However, some vitamin-mineral combinations reduced risk in subgroups defined by age, sex, and alcohol consumption. In contrast, gene expression patterns identified 11 genes in noncancerous l...
Researchers found that nimesulide, a COX-2 inhibitor, delayed the development of precancerous pancreatic lesions in mice by 90%, potentially offering a new approach to preventing pancreatic cancer in high-risk populations. The study suggests that inhibiting COX-2 may help slow or prevent the progression of pancreatic cancer.
A study of long-term female cancer survivors found that they valued sexuality but were not adequately prepared for the sexual issues introduced by their cancer or treatment. Discussing sexual consequences with physicians matters greatly to these patients, yet infrequent conversations occur.
Testicular cancer patients with metastatic disease can be cured with high-dose chemotherapy and a stem cell transplant, as shown in an Indiana University School of Medicine report. The treatment, which involves carboplatin chemotherapy at five times the standard dosage, has a success rate of over 90%.