Articles tagged with Cancer Patients
A study published in the Journal of the National Cancer Institute found that only 38 percent of U.S. hospitals were compliant with the guideline to examine 12 or more lymph nodes in colon cancer patients by 2004-2005, despite being recommended since 1997. Compliance increased from 15% to 38% over the eight-year period.
Researchers found that IKKalpha acts as a sentry to monitor and regulate keratinocyte proliferation, preventing the development of squamous cell carcinomas. Deleting IKKalpha induced cancer in mouse models by activating the epidermal growth factor receptor pathway.
A new analysis reveals that fewer than half of older patients with colorectal cancer receive the recommended screening schedule to detect any recurrence. The study found that some patients may not meet guideline standards due to other procedures, while others receive testing that goes beyond guidelines.
Debra DeMella, a brain tumor survivor, received the 2008 Survivor Circle Award from the American Society for Radiation Oncology (ASTRO) for her dedication to helping others living with cancer. She founded Brainstormers, a brain tumor support group, and served on various boards to improve quality of life for patients.
Researchers at M.D. Anderson Cancer Center discovered that 50% of HER2-positive breast cancer patients showed no signs of disease after surgery treated with Herceptin. However, some patients developed tumors that converted from HER2 positive to negative status, suggesting potential resistance to the therapy.
The VCU Massey Cancer Center is spearheading a phase II clinical study for certain sub-types of non-Hodgkin's lymphoma, combining the novel drugs bortezomib and vorinostat. The study aims to assess the effectiveness and side effects of this drug regimen in patients whose disease has progressed following treatment with other regimens.
The World Cancer Declaration aims to tackle the growing cancer crisis in developing countries with 11 cancer-busting targets for 2020. The plan focuses on significant drops in tobacco consumption, obesity and alcohol intake, as well as universal vaccination programs and proper pain medication.
Researchers at TGen and Washington University School of Medicine have discovered a new approach to treating endometrial cancer using a commercially available inhibitor drug. The study found that the drug can stop tumor growth and kill cancer cells, even in cases where the tumors contain a commonly occurring mutant gene.
A prospective cohort study of 6107 Chinese patients with type 2 diabetes found a V-shaped risk relation between LDL cholesterol and cancer. Patients with low LDL cholesterol (below 2.80 mmol/L) or high levels (above 3.90 mmol/L) had significantly elevated risks of various cancers.
Research led by Beth Israel Deaconess Medical Center identifies a previously unrecognized problem faced by mTORC1 inhibitors: activating the MAPK pathway, which encourages cancer cell survival. Scientists found that combining mTORC1 and MAPK inhibitors may offer a new treatment option for cancer patients.
A UK-led team of scientists has developed a more accurate way of identifying aggressive forms of bowel cancer, which should lead to better treatment and survival rates. The study found that patients with a stem cell marker protein called Lamin A present in their tissue are more likely to have an aggressive form of the disease.
Researchers have developed a more accurate way to identify aggressive bowel cancer forms, suggesting patients with the Lamin A marker should receive chemotherapy in addition to surgery for improved recovery and survival. The study aims to develop a robust prognostic tool for widespread use in bowel cancer treatment.
Despite five years of systemic therapy, breast cancer patients remain at risk for disease recurrence. Women with hormone receptor-positive cancer have a higher risk of relapse, highlighting an unmet clinical need for new strategies to reduce this risk.
Researchers identified specific HBV genotypes and mutations associated with increased liver cancer risk, including genotype C and basal core promoter mutation A1762T/G1764A. A combination of doxorubicin and zoledronic acid was found to reduce tumor size substantially in a mouse model of breast cancer.
A study led by M. D. Anderson Cancer Center found that risk assessment can help determine the probability of breast cancer recurrence, allowing clinicians to make informed decisions about extended therapy. The research analyzed data from 2,838 women diagnosed with Stage I-III breast cancers and treated with adjuvant systemic therapy.
Researchers at the University of Chicago Medical Center found that targeted radiation therapy can eradicate all signs of disease in up to 21% of patients with stage-IV cancer who have only a few sites of metastasis. The treatment was well-tolerated, with limited side effects, and showed promising results in controlling tumor growth.
A recent American Cancer Society study found that nearly half of cancer survivors used complementary methods such as prayer and meditation to cope with their condition. The study also revealed that women, younger survivors, and those with higher incomes were more likely to use these methods.
Researchers found that standard flu vaccine boosted immune function in patients with recurrent or metastatic Ewing's sarcoma and alveolar rhabdomyosarcoma, leading to higher five-year overall survival rates. The study suggests immunotherapy could be beneficial for high-risk pediatric sarcomas.
The Kenneth B. Schwartz Center and ASTRO are partnering to raise awareness of cancer survivorship through the Survivor Circle exhibit at ASTRO's Annual Meeting. The center supports compassionate healthcare and education, and will participate in the exhibit to promote its mission.
A randomized controlled trial found that removing H. pylori bacteria from stomachs of post-operative stomach cancer patients can significantly reduce the risk of stomach cancer redeveloping. The study showed a two-thirds reduction in metachronous gastric cancer development between eradication and control groups.
A recent review of the literature found that hormone deprivation therapy can have subtle adverse effects on cognition in prostate cancer patients. Studies indicate that between 47% and 69% of men treated with androgen depletion therapy decline in at least one cognitive area, primarily in spatial ability and high-order capacities.
The report found that paediatric-oncology care varied substantially between countries, with access to care or management extremely poor in seven out of ten nations. The five-year survival rate was as low as 5% in some countries, while higher rates were observed in those with greater health expenditure and infrastructure.
A recent review of literature found that hormone deprivation therapy can have subtle adverse effects on cognition in prostate cancer patients, affecting recall, concentration, and high-order capacities. Between 47% and 69% of men treated with androgen depletion therapy decline in cognitive function.
The presence of an impurity called ethyl methanesulfonate (EMS) in Roche's Viracept HIV medication did not increase patients' risk of developing cancer, according to new research confirmed by the European Committee for Human Medicinal Products (CHMP).
A new study from Saint Louis University has identified the PET-CT scanner as a reliable tool for detecting secondary cancers in head and neck cancer patients. The research suggests that this technology can replace traditional tests, allowing patients to begin treatment earlier and potentially improving outcomes.
A new study from Northwestern University found that cancer patients treated at high-volume hospitals have more lymph nodes examined for cancer spread, leading to improved long-term outcomes. This increased nodal evaluation can accurately diagnose stage disease and predict patient prognosis.
Researchers developed an injectable vaccine grown in genetically engineered plants to treat follicular B-cell lymphoma, a chronic and incurable disease. The plant-grown vaccines lack side effects and could allow earlier, more aggressive management of the cancer.
Patients with gastric or pancreatic cancer treated at high-volume hospitals or comprehensive cancer centers receive more thorough lymph node evaluations. This practice is associated with better prognosis and treatment decisions for these patients.
A gene expression test could help determine which patients need more aggressive treatment, improving lung cancer survival rates. The study used a large dataset of lung cancer tissue samples to analyze hundreds of genes and predict patient outcomes.
A recent study found that immunosuppressive drugs like cyclosporine increase the expression of vascular endothelial growth factor (VEGF), which can signal tumor growth after organ transplantation. The researchers suggest that targeting VEGF with anti-VEGF therapies may reduce cancer risk in transplant patients.
Multidetector CT with virtual gastroscopy and post-contrast enhanced multiplanar reformation images help differentiate cancerous lesions from benign ulcer lesions. The study found high specificity in diagnosing malignant gastric ulcers, potentially improving survival rates.
A worldwide study found significant differences in cancer survival rates between rich and poor countries, as well as between black and white men and women in the US. Cancer survival varies widely across regions, with some countries having much higher or lower survival rates than others.
A new study from the University of Michigan Comprehensive Cancer Center finds that more than three-quarters of bladder cancer patients are unaware of the link between smoking and bladder cancer. Quitting smoking can decrease the risk of developing bladder cancer by 40% within four years.
Researchers identified resveratrol as a substance with anti-breast cancer properties by blocking estrogen DNA adducts. The study suggests that resveratrol may play a crucial role in preventing breast cancer.
A new nurse-delivered complex care package has been shown to reduce levels of depression in cancer patients and improve their quality of life. The intervention, known as Depression Care for People with Cancer, was found to be cost-effective, with a median cost per quality-adjusted life-year gained of £10,000.
A clinical trial found that motesanib diphosphate, a VEGF inhibitor, slowed disease progression in some patients with metastatic thyroid cancer. The study also identified a genetic mutation associated with better response rates, offering potential for personalized therapy.
Scientists are testing a new cancer treatment that uses transfused white blood cells to combat advanced forms of cancer. The treatment, called Leukocyte InFusion Therapy (LIFT), has shown promising results in lab mice and aims to replicate those findings in human patients.
A study showed that Caphosol use led to lower OM rates and severity, as well as low pain medication use and high patient satisfaction among cancer patients. High efficacy ratings were also reported by physicians.
A panel of seven biomarkers can predict prostate cancer risk with high accuracy, offering a major step forward in patient care. Elevated levels of these biomarkers were associated with increased risk of relapse, and the combination of all seven variables accurately predicted risk 86.6 percent of the time.
A new study by the American Cancer Society finds that individuals with low socioeconomic status have more advanced cancers at diagnosis, receive less aggressive treatment, and have a higher risk of dying in the five years following cancer diagnosis. The study supports the need to focus on socioeconomic status as an important underlying...
A synthetic cocoa chemical slowed growth and accelerated destruction of human tumors in laboratory studies, suggesting it may be used for cancer chemoprevention or treatment. The strongest response was seen in colon cancer cells, with growth cut in half and most tumor cells damaged.
The medical profession and national governments must develop strategies to meet the challenge of caring for survivors of teenage and young adult cancers. Cancer patients face a double whammy: the burden of the disease and the burden of treatment, leading to increased risk of second cancers, infertility, and long-term health issues.
The cost of cancer care for elderly patients in the US increased significantly between 1991 and 2002 due to rising costs of radiation therapy and chemotherapy. The average cost per patient for lung, colorectal, and breast cancers rose substantially during this period.
A new mobile phone system allows young cancer patients to record and send their symptoms to medical professionals, providing valuable information on a day-to-day basis. This can transform the way young people with cancer are cared for, giving them independence and confidence in managing their symptoms.
Delays in diagnosis of teenagers and young adults (TYAs) with cancer can range from four to 184 weeks, with the average time being 15.2 weeks. A study found that out of 207 young people with cancer, four out of five sought medical help quickly, while only seven per cent delayed for months.
A young patient was diagnosed with Hodgkin lymphoma after a 10-month delay due to referral pathway and hospital system errors. The delay resulted from incorrect referrals to non-cancer specialists, leading to prolonged delays in diagnosis and treatment.
A substantial proportion of rectal cancer patients receive inappropriate surgical care due to wide variations in practice. The use of abdominoperineal excision (APE) rates have declined, but disparities persist among different regions and surgeon experience levels.
A family history of colorectal cancer is associated with a significant reduction in cancer recurrence and death, especially among patients receiving chemotherapy treatment. The study found that having more affected first-degree relatives further increased the protective effect, suggesting a distinct underlying molecular mechanism.
Researchers at UPMC Cancer Institute have developed a new treatment combination that combines chemotherapy, biotherapy, and radiotherapy to treat pancreatic cancer. The study found that this regimen is safe and may be beneficial for patients, with significant tumor shrinkage before surgery.
A new nomogram model predicts the probability of renal cancer recurrence 12 years after initial treatment, using tumor and patient characteristics to maximize predictive accuracy. The model helps clinicians counsel patients and customize treatment recommendations for individual patients.
A randomized, controlled trial found acupuncture significantly reduced pain, dysfunction, and dry mouth in head and neck cancer patients after neck dissection. The study also showed improvements in xerostomia, a common problem among cancer patients following radiotherapy.
A study by OHSU Cancer Institute researchers found that nearly 67% of stomach cancer patients are not getting the best therapy, despite compelling clinical data available since 2001. The study also showed a five-month survival advantage for patients who received chemotherapy and radiation therapy.
A study led by Dana-Farber Cancer Institute researchers found that black patients with advanced cancer were more likely to die in a hospital intensive care unit than white patients. The findings suggest that black patients may have a stronger preference for life-extending treatment, despite having a terminal prognosis.
A U-M study found that patients with poor physical quality of life, particularly those experiencing pain, eating, and speech difficulties, are significantly less likely to survive. The researchers recommend routine quality of life assessments for head and neck cancer patients to identify potentially aggressive tumors.
A gene therapy called Advexin has shown significant improvement in survival rates for patients with end-stage head and neck cancer by restoring tumor-suppressor gene p53 expression. Patients with a favorable p53 profile experienced a median survival of 7.2 months, compared to 2.7 months for those with an unfavorable profile.
Long-term cancer survivors are experiencing unmet needs for symptom management, leading to a poor quality of life. The European CanCer Organisation is working to bridge the gap between oncology and palliative care to provide comprehensive care for all stages of disease.
A genetic disorder previously associated with lung disease may also increase lung cancer risk, according to a study. Researchers found that carriers of the disorder had a 70-100% increased risk of lung cancer compared to non-carriers.
A new method of chemosensitivity testing was found to provide predictive information that could lead to better treatment outcomes for gastric cancer patients. The study's results showed a longer overall 5-year survival time in the sensitive group compared to the control group.
Researchers developed a blood test that can detect lung cancer in its earliest stages with high accuracy, potentially eliminating the need for invasive biopsies. The test uses gene expression analysis of circulating white blood cells and showed an 87% accuracy rate.
A new study published in the Annals of Internal Medicine has found that sequential therapy is superior to standard treatment for eradicating H. pylori, with potential implications for future treatments. Additionally, the study reveals a higher risk of certain cancers among HIV-infected patients and suggests a possible association betwe...