Articles tagged with Cancer Patients
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A new guide from Northwestern University helps doctors navigate fertility preservation strategies for cancer patients. The guide aims to increase awareness and improve treatment options for adolescents and younger adults facing cancer diagnosis.
Daniela Trani, a postdoctoral fellow at Georgetown University Medical Center, has been selected as an NSBRI Postdoc Fellow to investigate the effects of space radiation exposure on human health. Her research aims to understand injury responses to space radiation-induced inflammatory signaling in cells.
The City College of New York and Memorial Sloan-Kettering Cancer Center will receive funding to develop a unique partnership in cancer research, training, and community outreach. The grant aims to address cancer disparities in underserved minority communities through translational research, education, and outreach programs.
A study published by the American Cancer Society found that patients seeking health information online are more likely to be aware of and receive the latest cancer treatments. Patients who search for information on targeted therapies like Avastin and Erbitux are up to 3.22 times more likely to receive these treatments.
A new study reveals liver cancer incidence has tripled in the US since 1975, with African-Americans and Hispanics experiencing significant increases. Survival rates have improved significantly, with one-year rates rising from 25% to 47%, thanks to earlier diagnosis and treatment.
A randomised trial of 1590 cancer patients found no benefit of warfarin in reducing catheter-related thrombosis. However, dose-adjusted warfarin showed a reduced risk of thromboses compared to fixed-dose warfarin. The study concludes that warfarin is not a viable option for thromboprophylaxis in cancer patients.
Researchers have generated altered immune cells that target mesothelin, a protein highly expressed on cancer cells, shrinking and sometimes eradicating large tumors in mice. The approach shows promise for immunotherapies against certain tumors.
A study published in the Journal of the American Geriatrics Society found that black and Asian patients with terminal cancer use hospice care services less frequently than white and Hispanic patients, despite comparable levels of physical health and income.
A new test can predict which women with breast cancer are likely to respond to chemotherapy and which type of chemotherapy will work best for them. The test, known as the Breast Bioclassifier, has been validated on thousands of women and can help doctors prescribe targeted treatments that may not require chemotherapy.
Researchers found immunological tests to be more accurate in detecting precancerous lesions, identifying over twice as many lesions as HaemOccult test. However, some tests yielded too many false positives, emphasizing the need for high detection rates and reliable all-clears.
A study by Michigan State University found that higher medical mistrust among minority women led to late breast cancer screening. The AACR is working to address these issues through research and education. Recruiting diverse patients into clinical trials also poses challenges, with incentives often not effective.
More than a million cancer survivors in the US are forgoing necessary medical care due to financial constraints. Minority groups, particularly Hispanics and African-Americans, face significant barriers to accessing affordable care, affecting dental care, prescription medication, and mental health services.
A study published in the Journal of Clinical Oncology found that leaving the ovaries intact during surgery for early-stage endometrial cancer has no survival benefit compared to removing them. This approach could spare women from surgery-induced early menopause, hot flashes, and increased risk of heart disease and osteoporosis.
A new study has identified certain patient and tumor characteristics that may indicate which breast cancer patients are at high risk of developing contralateral breast cancer. These include histologic invasive characteristics, multiple quadrants affected, and a high Gail risk score or age over 50 at diagnosis.
Researchers discovered how anthracycline chemotherapy drugs block cancer cell growth by inhibiting HIF-1 protein. The findings suggest that these drugs may benefit a subgroup of cancer patients with high HIF-1 levels, leading to reduced tumor size and fewer blood vessels in mice.
A new study found that breast cancer survivors are unsatisfied with the post-cancer care they receive from their primary care physicians, highlighting the need for more coordinated care. Patients advocate for educational interventions and specialized clinics to address late effects of treatments and prevent disease recurrences.
Research from Thomas Jefferson University reveals that African-American patients with colorectal cancer are more likely to present with advanced disease and have a worse five-year survival rate. Socioeconomic factors, including access to healthcare screening, may contribute to these disparities.
Researchers at M.D. Anderson Cancer Center identified genetic variants in seven DNA repair genes associated with an increased risk of pancreatic cancer. The LIG3 G-39A AA variant was found to lower pancreatic cancer risk, while the ATM D1853N AA variant increased risk by over twice as much.
Research reveals bladder cancer is more lethal in women and African-Americans, with mortality rates up to 114% higher than their white male counterparts. The study found that traditional factors accounting for only part of the difference, suggesting other important factors are at play.
Researchers identified anthocyanins in black raspberries as effective in preventing esophageal cancer in rats. The study demonstrates the importance of anthocyanins as preventive agents in black raspberries and validates similar in vitro findings.
A study led by St. Jude Children's Research Hospital identified mutations in the IKZF1 gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL). The findings suggest that this genetic marker could be used to tailor treatment intensity and improve patient outcomes.
Researchers have discovered two enzymes involved in DNA demethylation, which could lead to targeted therapies aimed at slowing or preventing cancer. The enzymes control an 'on-and-off switch' for critical genes that trigger cancer and other diseases.
Researchers at UC Davis Cancer Center have identified three compounds that can help make chemotherapy for kidney cancer more effective by blocking the repair mechanism of a key cancer gene. These findings offer hope for patients who currently face limited treatment options and many side effects.
A new study at Ohio State University Medical Center has successfully grown human blood platelets in a laboratory for transfusion. The three-dimensional bioreactor produced up to 1.2 million platelets per day, continuing production for over 32 days.
A combination of prophylactic antibiotics, barrier isolation, and air quality control measures significantly reduces mortality risk in immunocompromised cancer patients. The intervention shows a 40% reduction in all-cause mortality at 30 days post-treatment, with improved survival only seen when antibiotic and anti-fungal prophylaxis a...
A recent study by the University of Alberta found that individuals with sarcopenic obesity, a condition characterized by low lean muscle mass, had significantly reduced survival rates and poorer physical function compared to those with only obesity. This suggests that body composition may play a crucial role in cancer treatment outcomes.
A meta-analysis of studies found that patients with diabetes diagnosed with cancer have a higher risk of death compared to those without diabetes. The study, published in JAMA, suggests that pre-existing diabetes is associated with an increased risk of all-cause death following cancer diagnosis across various cancer types.
A recent study published in The Journal of Urology found that low-income men are diagnosed with more advanced prostate cancer due to inadequate access to screening services. This disparity is significant, as the study reveals that 19% of these men were diagnosed with metastatic cancer, compared to 4% in the general population.
GUMC researchers discovered PTPRD gene inactivation in melanoma and glioblastoma, a potential tumor suppressor role. The findings suggest a wide applicability of PTPRD in various cancers, paving the way for novel therapy.
A planned safety analysis of a breast cancer prevention study using exemestane found an acceptable level of bone loss in postmenopausal women. The study also suggests that the long-term clinical impact of this decrease is not yet known, and further research is needed.
A large study found that early-stage HER2-positive breast cancer patients with tumors one centimeter or smaller have a 23% chance of recurrence, highlighting the need for additional therapy. The study's findings suggest that physicians should consider offering Herceptin-based therapy to these patients.
The majority of oral cancers are found late, causing high mortality rates, but early diagnosis improves survivability to 95% and reduces morbidity. Prosthodontists must change their practice paradigm by performing regular oral cancer screening examinations on all patients.
Researchers at the University of Texas M. D. Anderson Cancer Center have developed a new three-drug combination therapy that spares patients from prolonged myelosuppression, a potentially lethal side effect of traditional treatments. The treatment achieved a remission rate of 96% in patients with indolent B cell lymphoma.
A study published in Cancer Prevention Research suggests that selenium may aid in the prevention of high-risk bladder cancer. Women, moderate smokers, and those with p53 positive bladder cancer had significant reductions in bladder cancer with higher rates of selenium.
A lack of clear-cut scientific evidence has created controversy over breast cancer screening for women over 80. Researchers recommend investing in clinical trials to assess cancer screening and treatment for older individuals, strengthening empirical data for medical recommendations.
A long-term study found that high insulin-like growth factor binding protein-1 (IGFBP-1) levels reduced overall death risk by over 50%, while high C-peptide levels doubled the risk of death. Lifestyle factors like obesity and physical inactivity are associated with high insulin levels, which can fuel colon cancer growth.
A clinical trial at Ohio State University found that older AML patients responded well to a less toxic therapy, achieving complete remission in 42% of cases. The treatment involved decitabine and showed promising results for this 'silent majority' of patients who previously were told they had no chance of treatment.
Researchers at M. D. Anderson Cancer Center have developed a new risk model for myelodysplastic syndrome (MDS) that applies to patients at any stage of the disease. The model provides improved survival projections and treatment guidance, offering hope for better patient outcomes.
A previously dismissed leukemia drug, flavopiridol, has shown promising results in treating CLL patients with advanced chromosomal abnormalities. In a two-phase trial involving 116 patients, approximately half responded to treatment.
In a phase II clinical trial, lenalidomide demonstrated activity against chronic lymphocytic leukemia in elderly patients. The drug showed a favorable toxicity profile and achieved significant responses, including partial response in 54% of patients.
Researchers at M.D. Anderson Cancer Center analyzed over 1,100 blood stem cell transplantations and found that older patients (65+) do not have poorer outcomes compared to younger patients. The study also showed that disease type and status at transplant are key prognostic variables for survival.
The University of Texas M. D. Anderson Cancer Center is hosting its first international conference on inflammatory breast cancer to bring together clinicians and scientists to share new clinical discoveries and educational workshops. The conference aims to improve diagnosis and management of this rare but deadly disease through joint i...
Lapatinib shows improved progression-free survival for women with HER2-positive metastatic breast cancer compared to chemotherapy alone. However, high-volume laboratories misclassify some patients, preventing them from receiving optimal therapy.
Researchers found blood transfusions in hospitalized cancer patients increased venous thromboembolism (VTE) and arterial thromboembolism (ATE) rates, comparable to erythropoiesis-stimulating agents (ESAs). This study highlights the need for cautious use of transfusions and exploration of ways to reduce clot risk in cancer patients.
Head and neck cancer patients with comorbidities have a significantly higher risk of death, with some cases increasing by up to seven-fold. The study highlights the importance of considering co-existing conditions in estimating cancer survival statistics.
A study published by the American Association for Cancer Research found that cruciferous vegetables like broccoli may lower lung cancer risk in smokers. The study showed a significant protective effect, with risks ranging from 20% to 55% depending on the type and duration of smoking.
A meta-analysis published by the American Association for Cancer Research found that individuals with HIV have a higher risk of non-AIDS cancers compared to the general population. The risk is significantly higher for men than women, and incidence rates are similar between those with AIDS and without.
Researchers found that home-based diet and exercise interventions improved physical functioning in older, long-term cancer survivors. Participants in the intervention group demonstrated significant improvements in their diet and exercise behaviors, as well as measures of basic and advanced lower extremity functioning.
GUMC researchers will present several scientific findings on black women's health, including the importance of colonoscopy utilization and BRCA1/2 genetic testing. Studies reveal predictors of genetic testing among newly diagnosed breast cancer patients, highlighting the need for clinical practice to identify patients at risk.
Researchers found associations between lifestyle, behavioral, and demographic variables on cancer risk among the elderly, including moderate physical activities decreasing cancer risk. Tobacco consumption was also linked to lung cancer, while comorbidities increased breast and prostate cancer risk.
A landmark trial is underway to assess whether COLD-FX reduces infections in chronic lymphocytic leukemia patients, who are vulnerable to respiratory infections due to weakened immune systems. The study aims to evaluate the effectiveness of COLD-FX in preventing and treating viral respiratory infections.
The study found that CAPHOSOL results in a low incidence of oral mucositis, moderate to severe pain, and dysphagia. Patient satisfaction rates were high, with 79% describing themselves as satisfied or very satisfied with the treatment.
A randomized clinical trial found that breast cancer patients who participate in psychological intervention sessions experience reduced stress, improved mood, and altered health behaviors. This led to a significant decrease in cancer recurrence and death from breast cancer, as well as overall mortality.
Researchers found that DFMO treatment reduced dysplasia progression in patients with Barrett's esophagus, while also lowering putrescine levels and KLF5 expression. The study suggests a potential mechanism for the chemopreventive effects of DFMO.
A large-scale clinical trial found no significant protection against cancer from long-term vitamin E or C supplements. Researchers followed over 14,000 physicians for up to 10 years without detecting a link between these supplements and reduced cancer rates.
Researchers at Medical University of South Carolina present a new theory that may lead to effective heart failure treatments by identifying the role of matrix metalloproteinases (MMPs) in the disease. The study suggests that MMPs, similar to those found in cancerous tumors, contribute to the progression of heart failure, leading to the...
The report aims to improve cancer clinical trial participation, particularly among racial and ethnic minorities and low-income groups. It recommends integrating community representatives into the research development process and disseminating results in ways that patients can understand.
Researchers found that the use of predictive biomarkers and targeted therapies significantly delayed the need for conventional chemotherapy in patients with early-stage but high-risk chronic lymphoid leukemia (CLL). The study resulted in a four-year delay in treatment compared to two years, showing promising results for personalized care.
A study of over 200 cancer patients found that age was not a significant factor in survival rates. Instead, factors like physical quality of life and metastatic dissemination played a crucial role. The findings suggest that older patients should not be excluded from clinical trials due to their age.
Researchers at Washington University sequenced a cancer patient's genome to discover 10 unique genetic mutations relevant to her acute myelogenous leukemia. The study sets the stage for using comprehensive genome-wide approaches to diagnose and treat cancer.