Articles tagged with Cancer Patients
A study highlights the need for better training and education in the dental community to discuss HPV prevention methods with patients. Most dentists don't address HPV-related oropharyngeal cancers due to lack of knowledge and communication skills.
A clinical trial investigates whether dietary and exercise interventions can decrease AGEs, which have been linked to cancer, in prostate cancer survivors. Preliminary data suggest that AGEs may be a better biomarker for lifestyle changes than previously used markers.
A recent study has found that cancer patients given fluids at the end-of-life stage live significantly longer than those who don't receive such treatment. This results in an average of one-and-a-half more days of life, as well as better symptom control and minimal side effects.
A retrospective analysis of 73 lung squamous cell carcinoma patients found that higher body mass index and younger age were linked with longer progression-free survival. Patients with a better response to treatment also had longer overall survival.
Researchers found that DNA repair-related biomarkers, including BRF1, BRCA1/2, and MPO, can predict outcomes in gastric cancer patients who abuse alcohol. These biomarkers were associated with disease recurrence, survival rates, and response to chemotherapy.
A new study reveals significant healthcare disparities among patients aged 80 and older with advanced lung cancer. African Americans and those from lower-income areas are more likely to not receive standard care therapy, leading to poorer outcomes. In contrast, patients receiving standard treatment live longer.
New research identifies characteristics of women who need extra support to self-manage their lymphedema, highlighting the importance of a 'stepped-care' approach. Advances in imaging techniques and technologies offer opportunities for improved patient monitoring and control.
Researchers found that germline variations in the tumor suppressor gene TP53 predispose children to develop leukemia and increase their chances of developing a second cancer. The variants are associated with reduced gene activity and were five times more frequent in pediatric ALL patients than those without the disease.
A team of researchers is developing complex computer models to predict how cancer will progress in individual patients. They use advanced computing resources, including those at the Texas Advanced Computing Center, to analyze patient-specific data from imaging tests and biopsies, as well as other factors.
A recent study found that smokers who use e-cigarettes tend to smoke less and have increased quit attempts, making them a potentially valuable tool for quitting smoking. The study also showed that higher-dose e-cigarettes had stronger outcomes, with participants smoking an average of 37% fewer cigarettes.
A study published in the American Journal of Public Health found that Medicaid expansion led to a significant increase in early-stage cancer diagnoses, particularly among those aged 35-54. The research suggests that public health insurance may increase cancer detection, resulting in fewer cancer deaths and better patient outcomes.
A study by the University of Houston found that over half of young cancer patients reported problems with sexual function. The probability of reporting sexual dysfunction increased over time, affecting 53% of participants two years after diagnosis. Relationships and psychological distress also played a role in sexual health.
Researchers developed an algorithm using smartphone data to detect worsening symptoms in cancer patients, allowing for early intervention and improved quality of life. The study enrolled 14 patients undergoing chemotherapy treatment, showing 88% accuracy in identifying high-symptom days.
Researchers have discovered that T cells with a protein called CD26 on their surface are highly effective against aggressive solid tumors. These cells, previously overlooked in cancer immunotherapy, can resist apoptosis and repopulate after infusion, making them ideal for adoptive cell transfer therapy.
A new study found that factors such as persistent symptoms, comorbidities, leisure-time physical activity, and financial challenges affect health-related quality of life in older adults with cancer. The research highlights the importance of comprehensive care that addresses these factors to improve outcomes for this vulnerable population.
The ESMO Position Paper emphasizes the need for patient-centered care in cancer treatment, addressing physical, psychological, social, and spiritual needs. It calls for increased awareness, research, education, and resources for supportive and palliative care.
Researchers present promising results from clinical trials suggesting patients with blood disorders and several types of cancer will soon have expanded treatment options. The studies show significant breakthroughs in reducing risks during rare blood disorders, such as thrombotic thrombocytopenic purpura, and improving treatment for mul...
Researchers have invented a method to detect tiny tumors and track their spread using light-emitting nanoprobes, potentially leading to earlier cancer detection and more precise treatment. The technology has shown better results than magnetic resonance imaging (MRI) in detecting small cancerous lesions.
Researchers developed a simple MRI technique to analyze brain tumors, finding that immune reactive cells around the tumor are associated with longer patient survival. This non-invasive method could provide an easier way for doctors to prescribe the most appropriate cancer treatment.
Researchers propose a revised cancer staging approach that incorporates liquid biopsy to improve diagnosis and treatment accuracy. The new system has shown promising results in guiding cancer care, particularly in detecting early-stage cancer and tracking treatment response.
Researchers found that Apple Watch activity data correlated with standard patient-reported outcome measures, including physical function and quality of life. The study used emojis to measure quality of life, which showed significant associations with traditional scales.
A study by Lancaster University researchers suggests that spontaneous humour is used and appreciated by people with cancer as a way to deal with taboo or embarrassing situations. The research found that using humorous metaphors can empower patients by undermining their illness, mocking it, and distancing themselves from it.
A recent study published in Annals of Behavioral Medicine found that higher Fitbit step counts during inpatient recovery were associated with lower risk of readmission after metastatic peritoneal cancer surgery. The researchers monitored patients using Fitbits and found that more activity was linked to better patient outcomes.
A University of Houston researcher is developing a new approach to prevent esophageal cancer by targeting precursor lesions like Barrett's esophagus. By cloning stem cells from these lesions, the researcher hopes to identify drugs that can selectively kill them before they progress to cancer.
Differences in gene expression between non-small cell lung cancers from African-Americans and European-Americans suggest racial disparities in NSCLC biology. The study identified distinct patterns of gene expression involved in stem cell biology and invasive behavior in African-American NSCLCs.
Researchers at the University of Cincinnati have developed a targeted treatment that can prevent the spread of pancreatic cancer and protect the heart from damage. The treatment, which involves using an mTOR kinase inhibitor, has shown promise in reducing disease progression and cardiac impairment in patients with certain types of tumors.
Research reveals that cancer survivors experience difficulty conceiving and increased embryo loss, while their children's health remains unaffected. The study highlights the need for continued monitoring across multiple generations to understand the long-term effects of chemotherapy.
A new study analyzed breast cancer tumor samples over time, revealing common characteristics among treatment-resistant tumors. The research aims to understand tumor changes in real-time to adjust treatment accordingly.
A study found that 11% of younger cancer patients and 25% of older adults developed new cancers between 2009-2013. This prevalence highlights the need for better research representation and outcomes among survivors.
The Cure Brain Cancer Foundation has awarded a $345,000 fellowship to Dr Ryan Cross to develop cancer-fighting immune T cells for brain cancer treatment. The research aims to improve patient survival rates and develop personalised treatments for children and adults with brain cancer.
A recent study found that approximately one-fifth of cancer patients develop PTSD several months after diagnosis. Researchers emphasize the need for early identification and treatment to improve psychological well-being and quality of life.
Researchers at Ohio State University Wexner Medical Center identified a substance called Gdf-15, released by pancreatic cancer cells, that protects them from immune cell macrophages. GDF-15 inhibits nitric oxide and tumor necrosis factor production in macrophages, allowing tumor cells to survive and grow.
A study by UNC Lineberger Comprehensive Cancer Center led to the development of a new approach for identifying therapeutic options for cancer patients based on their tumor's genetics. Cognitive computing was used to analyze large volumes of data and identify potentially relevant clinical trials or treatment options.
A national cooperative group trial is making a handful of experts in rare leukemia available around the clock to reduce high mortality rates. The goal is to decrease induction mortality from 30% to 6.7% by providing timely management and care for patients with acute promyelocytic leukemia.
A study in Myanmar found that all mouth cancer patients use smokeless tobacco, with betel quid chewing being a common habit among the population. The study highlights the importance of increasing awareness about the risks of betel quid chewing to prevent head and neck cancer.
The ESMO International Consortium Study found dramatic disparities in access to anti-cancer medications, even among essential medicines recommended by the World Health Organization. In Lower Middle- and Low-Income countries, many essential medications are available only at full cost, limiting accessibility.
A recent study reveals that over a quarter of cancer survivors experience poor quality of life post-treatment, with significant unmet needs in eight out of ten countries. The study highlights the need for comprehensive survivorship care and coordinated resources to support cancer patients.
A new project led by Queen Mary University of London aims to develop and test a talking-based therapy for cancer survivors, addressing issues such as fatigue, fear of recurrence, and concerns about returning to work. The therapy, Acceptance and Commitment Therapy (ACT), will be assessed in a full trial involving 344 participants.
A new study published in Gastroenterology found that health insurance coverage differences account for nearly half of the black-white survival disparity in colorectal cancer patients. The study analyzed data from 199,098 CRC patients aged 18-64 and found a significant impact of insurance status on treatment outcomes.
A new study from Dartmouth College finds that patients with depression and advanced cancer live longer when exposed to palliative care interventions designed to improve quality of life. The intervention showed improved survival rates for those higher in depression compared to the usual care group.
Researchers developed a hybrid Th1/17 T cell that combines the strong effector traits of Th1 cells with the durability of Th17 cells, providing a potent and durable anti-tumor response in preclinical models. The hybrid cells maintained their effectiveness even after long-term persistence in the body.
Women with ER-positive breast cancer still face a substantial risk of cancer returning or spreading even 20 years after diagnosis, according to a new analysis. The risk is directly tied to the original cancer's size and characteristics, as well as the number of lymph nodes involved.
Researchers at German Cancer Research Center discovered a link between energy metabolism and epigenetic code in leukemias and brain cancer. The enzyme BCAT1 plays a key role in the development of malignant tumors, including acute myeloid leukemia and breast cancer.
Scientists at Mount Sinai developed a mathematical model that accurately predicts how tumors will respond to immunotherapies. The model also identifies key neoantigens that can stimulate an immune response, offering new insights for developing personalized cancer treatments.
A new category of immunotherapies called checkpoint inhibitors shows promise in treating cancers in HIV patients, who were previously excluded from clinical trials. The ongoing study suggests that these drugs can be safely used to manage cancer in people with HIV, providing a new hope for this population.
Researchers at FAU have identified two mechanisms by which H. pylori destroys the stomach's protective layer, allowing bacteria to access deeper tissue layers and inflict further damage. The team also discovered that the injected bacterial toxin reprograms host cells, making them potentially cancerous.
A new HCI study reveals that a two-drug combination significantly reduces precancerous polyps in FAP patients, leading to near-complete blockade of cancer growth pathways. The treatment also activates immune responses aimed at destroying pre-cancerous polyps.
Current RECIST guidelines face challenges in measuring cancer response with emerging targeted therapies. Researchers propose a new baseline approach to track stability and separate tumor burden from treated areas.
A study of 1,678 RA patients found no increased risk of second malignancy among those treated with biologics after a primary cancer diagnosis. Hazard ratios showed a slightly higher mortality rate among RA patients who received biologics before their cancer diagnosis.
Two studies reveal that gut bacteria play a crucial role in cancer treatment response, with certain beneficial microbes linked to improved survival and efficacy of immunotherapy. Patients with healthier gut flora tend to have more immune cells that can target tumors.
Researchers identified four genes - KRAS, CDKN2A, SMAD4, and TP53 - that influence pancreatic cancer survival. Patients with three or four altered genes had poorer disease-free and overall survival rates compared to those with single or dual alterations.
Preclinical studies demonstrate onalespib's effectiveness in inhibiting HSP90, reducing cell-survival proteins and tumor growth. The agent shows promise as a single treatment or in combination with temozolomide for glioblastoma patients.
Scientists at the University of Birmingham are pioneering a new approach to bowel cancer treatment using mini tumor models. The study, funded by Cancer Research UK, aims to identify new treatments and improve existing ones for this common yet deadly disease.
Researchers found that a diet low in glutamine can enhance chemotherapy's effectiveness and increase life span in mice with medulloblastoma. The study offers hope for improved treatments for childhood brain tumors, which are often associated with significant side effects.
Researchers found that PARP inhibitor talazoparib caused regression of patient-derived xenografts (PDXs) of triple-negative breast cancers (TNBC) lacking BRCA mutations. The study suggests that PARP inhibitors may be effective in selected patients with other alterations in DNA damage repair genes.
The Lancet Oncology Commission recommends prioritizing key areas for US$2 billion funding to advance cancer research and treatment, focusing on prevention, targeted interventions, and patient-centered data sharing. The report aims to improve cancer care for underserved groups and reduce health disparities.
A nationwide population-based study found that death rates from lupus remain high compared to the general population, with significant disparities observed among older persons, females, blacks, and Hispanics. The study suggests that targeted research and public health programs may help address these disparities.
CancerLinQ is a big-data, real-world health information technology system that enables near real-time access to individual patient data for informed decision-making. The platform allows practitioners and researchers to tap into longitudinal, de-identified data and analytics.
The American Cancer Society has awarded Boston University School of Medicine with a three-year, $270,000 Institutional Research Grants program award to support early-stage cancer research by junior faculty. This funding will provide grants per year and is valued for its opportunity to establish proof-of-concept.
A researcher has discovered a protein that drives tumor growth in gallbladder cancer, providing an important prognostic marker for improved patient outcomes. The findings may lead to more effective treatment options and new drug therapies.