Articles tagged with Cancer Patients
Researchers found that Apple Watch activity data correlated with standard patient-reported outcome measures, including physical function and quality of life. The study used emojis to measure quality of life, which showed significant associations with traditional scales.
A study by Lancaster University researchers suggests that spontaneous humour is used and appreciated by people with cancer as a way to deal with taboo or embarrassing situations. The research found that using humorous metaphors can empower patients by undermining their illness, mocking it, and distancing themselves from it.
A recent study published in Annals of Behavioral Medicine found that higher Fitbit step counts during inpatient recovery were associated with lower risk of readmission after metastatic peritoneal cancer surgery. The researchers monitored patients using Fitbits and found that more activity was linked to better patient outcomes.
A University of Houston researcher is developing a new approach to prevent esophageal cancer by targeting precursor lesions like Barrett's esophagus. By cloning stem cells from these lesions, the researcher hopes to identify drugs that can selectively kill them before they progress to cancer.
Differences in gene expression between non-small cell lung cancers from African-Americans and European-Americans suggest racial disparities in NSCLC biology. The study identified distinct patterns of gene expression involved in stem cell biology and invasive behavior in African-American NSCLCs.
Researchers at the University of Cincinnati have developed a targeted treatment that can prevent the spread of pancreatic cancer and protect the heart from damage. The treatment, which involves using an mTOR kinase inhibitor, has shown promise in reducing disease progression and cardiac impairment in patients with certain types of tumors.
Research reveals that cancer survivors experience difficulty conceiving and increased embryo loss, while their children's health remains unaffected. The study highlights the need for continued monitoring across multiple generations to understand the long-term effects of chemotherapy.
A new study analyzed breast cancer tumor samples over time, revealing common characteristics among treatment-resistant tumors. The research aims to understand tumor changes in real-time to adjust treatment accordingly.
A study found that 11% of younger cancer patients and 25% of older adults developed new cancers between 2009-2013. This prevalence highlights the need for better research representation and outcomes among survivors.
The Cure Brain Cancer Foundation has awarded a $345,000 fellowship to Dr Ryan Cross to develop cancer-fighting immune T cells for brain cancer treatment. The research aims to improve patient survival rates and develop personalised treatments for children and adults with brain cancer.
A recent study found that approximately one-fifth of cancer patients develop PTSD several months after diagnosis. Researchers emphasize the need for early identification and treatment to improve psychological well-being and quality of life.
Researchers at Ohio State University Wexner Medical Center identified a substance called Gdf-15, released by pancreatic cancer cells, that protects them from immune cell macrophages. GDF-15 inhibits nitric oxide and tumor necrosis factor production in macrophages, allowing tumor cells to survive and grow.
A study by UNC Lineberger Comprehensive Cancer Center led to the development of a new approach for identifying therapeutic options for cancer patients based on their tumor's genetics. Cognitive computing was used to analyze large volumes of data and identify potentially relevant clinical trials or treatment options.
A national cooperative group trial is making a handful of experts in rare leukemia available around the clock to reduce high mortality rates. The goal is to decrease induction mortality from 30% to 6.7% by providing timely management and care for patients with acute promyelocytic leukemia.
A study in Myanmar found that all mouth cancer patients use smokeless tobacco, with betel quid chewing being a common habit among the population. The study highlights the importance of increasing awareness about the risks of betel quid chewing to prevent head and neck cancer.
The ESMO International Consortium Study found dramatic disparities in access to anti-cancer medications, even among essential medicines recommended by the World Health Organization. In Lower Middle- and Low-Income countries, many essential medications are available only at full cost, limiting accessibility.
A recent study reveals that over a quarter of cancer survivors experience poor quality of life post-treatment, with significant unmet needs in eight out of ten countries. The study highlights the need for comprehensive survivorship care and coordinated resources to support cancer patients.
A new project led by Queen Mary University of London aims to develop and test a talking-based therapy for cancer survivors, addressing issues such as fatigue, fear of recurrence, and concerns about returning to work. The therapy, Acceptance and Commitment Therapy (ACT), will be assessed in a full trial involving 344 participants.
A new study published in Gastroenterology found that health insurance coverage differences account for nearly half of the black-white survival disparity in colorectal cancer patients. The study analyzed data from 199,098 CRC patients aged 18-64 and found a significant impact of insurance status on treatment outcomes.
A new study from Dartmouth College finds that patients with depression and advanced cancer live longer when exposed to palliative care interventions designed to improve quality of life. The intervention showed improved survival rates for those higher in depression compared to the usual care group.
Researchers developed a hybrid Th1/17 T cell that combines the strong effector traits of Th1 cells with the durability of Th17 cells, providing a potent and durable anti-tumor response in preclinical models. The hybrid cells maintained their effectiveness even after long-term persistence in the body.
Women with ER-positive breast cancer still face a substantial risk of cancer returning or spreading even 20 years after diagnosis, according to a new analysis. The risk is directly tied to the original cancer's size and characteristics, as well as the number of lymph nodes involved.
Researchers at German Cancer Research Center discovered a link between energy metabolism and epigenetic code in leukemias and brain cancer. The enzyme BCAT1 plays a key role in the development of malignant tumors, including acute myeloid leukemia and breast cancer.
Scientists at Mount Sinai developed a mathematical model that accurately predicts how tumors will respond to immunotherapies. The model also identifies key neoantigens that can stimulate an immune response, offering new insights for developing personalized cancer treatments.
A new category of immunotherapies called checkpoint inhibitors shows promise in treating cancers in HIV patients, who were previously excluded from clinical trials. The ongoing study suggests that these drugs can be safely used to manage cancer in people with HIV, providing a new hope for this population.
Researchers at FAU have identified two mechanisms by which H. pylori destroys the stomach's protective layer, allowing bacteria to access deeper tissue layers and inflict further damage. The team also discovered that the injected bacterial toxin reprograms host cells, making them potentially cancerous.
A new HCI study reveals that a two-drug combination significantly reduces precancerous polyps in FAP patients, leading to near-complete blockade of cancer growth pathways. The treatment also activates immune responses aimed at destroying pre-cancerous polyps.
Current RECIST guidelines face challenges in measuring cancer response with emerging targeted therapies. Researchers propose a new baseline approach to track stability and separate tumor burden from treated areas.
A study of 1,678 RA patients found no increased risk of second malignancy among those treated with biologics after a primary cancer diagnosis. Hazard ratios showed a slightly higher mortality rate among RA patients who received biologics before their cancer diagnosis.
Two studies reveal that gut bacteria play a crucial role in cancer treatment response, with certain beneficial microbes linked to improved survival and efficacy of immunotherapy. Patients with healthier gut flora tend to have more immune cells that can target tumors.
Researchers identified four genes - KRAS, CDKN2A, SMAD4, and TP53 - that influence pancreatic cancer survival. Patients with three or four altered genes had poorer disease-free and overall survival rates compared to those with single or dual alterations.
Preclinical studies demonstrate onalespib's effectiveness in inhibiting HSP90, reducing cell-survival proteins and tumor growth. The agent shows promise as a single treatment or in combination with temozolomide for glioblastoma patients.
Scientists at the University of Birmingham are pioneering a new approach to bowel cancer treatment using mini tumor models. The study, funded by Cancer Research UK, aims to identify new treatments and improve existing ones for this common yet deadly disease.
Researchers found that a diet low in glutamine can enhance chemotherapy's effectiveness and increase life span in mice with medulloblastoma. The study offers hope for improved treatments for childhood brain tumors, which are often associated with significant side effects.
Researchers found that PARP inhibitor talazoparib caused regression of patient-derived xenografts (PDXs) of triple-negative breast cancers (TNBC) lacking BRCA mutations. The study suggests that PARP inhibitors may be effective in selected patients with other alterations in DNA damage repair genes.
The Lancet Oncology Commission recommends prioritizing key areas for US$2 billion funding to advance cancer research and treatment, focusing on prevention, targeted interventions, and patient-centered data sharing. The report aims to improve cancer care for underserved groups and reduce health disparities.
A nationwide population-based study found that death rates from lupus remain high compared to the general population, with significant disparities observed among older persons, females, blacks, and Hispanics. The study suggests that targeted research and public health programs may help address these disparities.
CancerLinQ is a big-data, real-world health information technology system that enables near real-time access to individual patient data for informed decision-making. The platform allows practitioners and researchers to tap into longitudinal, de-identified data and analytics.
The American Cancer Society has awarded Boston University School of Medicine with a three-year, $270,000 Institutional Research Grants program award to support early-stage cancer research by junior faculty. This funding will provide grants per year and is valued for its opportunity to establish proof-of-concept.
A researcher has discovered a protein that drives tumor growth in gallbladder cancer, providing an important prognostic marker for improved patient outcomes. The findings may lead to more effective treatment options and new drug therapies.
Researchers have successfully tested a new molecule capable of preventing peripheral neuropathy induced by chemotherapy in cancer patients. The molecule has shown positive results in reducing the appearance of disorders associated with nerve dysfunction.
Two studies comparing robotic-assisted to laparoscopic surgical procedures found no significant differences in postoperative complications or quality of life for patients with renal mass or rectal cancer. Robotic-assisted surgery was associated with prolonged operating times and higher hospital costs, but not increased risk of major co...
Patients with advanced cancer who experience high levels of physical and psychological symptoms have longer hospital stays and higher risk of unplanned readmissions. Researchers found that symptom management is crucial for improving patient outcomes and quality of life.
Patients with advanced cancer experience frequent and prolonged hospitalizations, often due to moderate to severe fatigue, poor well-being, and depression. These symptoms are linked to longer hospital stays and a higher risk of unplanned hospital readmissions.
A new clinical trial found that a brief in-person intervention, PRISM, can improve psychosocial health and quality of life in adolescents and young adults living with cancer. The intervention cultivated internal and existential resources to strengthen stress management and goal-setting.
A study of nine women suggests that ovarian tumors may originate in the fallopian tubes, providing insights into cancer origin and potential prevention strategies. The researchers found identical genetic errors in chromosome 17 and BRCA genes in all patients, supporting the fallopian tube theory.
A new study found that patients with advanced cancer prefer face-to-face interaction with their doctors, with better communication skills and professionalism. After watching both videos, 72% of participants favored the face-to-face interaction, highlighting the importance of human connection in healthcare.
The study found that the uninsured rate for adults with new cancer diagnoses decreased from 5.73% to 3.81% in 2014, a gain of 1.92 percentage points across multiple cancers and demographic groups. Coverage gains were particularly significant for Hispanic individuals and those with early- or late-stage disease.
A national cancer survey found 23% of childhood cancer survivors experienced job lock, staying at jobs for health insurance coverage. Female survivors and those with chronic conditions were more likely to report job lock. The study highlights the need for education and literacy about insurance options to support employed cancer survivors.
A study found that young non-Hispanic white women who tan indoors are more likely to be dependent on indoor tanning due to beliefs about physical appearance and depressive symptoms. The research, published in Cancer Epidemiology, Biomarkers & Prevention, suggests a need for targeted interventions to address this behavior change.
A study published in JAMA Oncology found that the number of newly diagnosed cancer patients who were uninsured fell by one-third in the first year of the Affordable Care Act's implementation. Significant gains were seen among various demographic groups and stages of diagnosis, with declines in uninsured rates among Hispanics and those ...
Researchers found that on average, one to ten driver mutations are required for cancer to emerge. The study also reveals the number of mutations driving cancer varies considerably across different cancer types. By using an evolutionary approach, scientists can identify key genes and mutations involved in cancer evolution.
Researchers found that arsenic trioxide can be a powerful therapy for glioblastoma multiforme, extending patient survival by three to four times. The treatment targets specific genomic signatures of brain tumor cells, allowing for precision medicine and matching the right drug to the right patient.
Researchers identified effective treatments for patients with rare cancers through genomic analysis, resulting in stabilization, shrinkage, or remission for half the patients. Precision medicine offers new hope for managing these uncommon but significant cancers.
Scientists at Mount Sinai & Sema4 validated a biomarker indicative of glioblastoma patient prognosis and likely response to therapies. BUB1B-sensitive tumors had significantly worse prognosis but were more likely to respond to many drugs already in clinical use.
A new clinical trial, led by TGen's Dr. Von Hoff, will pair an immunotherapy drug with a Vitamin D Receptor agonist to treat pancreatic cancer. The study aims to remodel the tumor microenvironment and improve the delivery of immunotherapy.
The University of Texas M.D. Anderson Cancer Center has been selected as one of four national Cancer Immune Monitoring and Analysis Centers (CIMACs) under the Partnership for Accelerating Cancer Therapies (PACT). CIMACs will provide expertise in systematic collection, processing, and analysis of blood and tumor samples to improve immun...
The inaugural SU2C Catalyst projects aim to explore new uses for powerful medicines in combination with other pharmaceutical company medicines, devices, and therapies. This program supports the selection of proposals by industry-specific sub-committees and significantly expedites the process of going from ideas to contracts to trials.
A study published in JNCI Journal of the National Cancer Institute found that cryotherapy can prevent symptoms of chemotherapy-induced peripheral neuropathy, improving quality of life for cancer patients. Cryotherapy involves wearing frozen gloves and socks during chemotherapy to reduce pain, numbness, and tingling.
Researchers from SingHealth, Duke-NUS Medical School, and NCCS have sequenced the complete genetic blueprint of durian, a tropical fruit known for its unique smell. The study reveals that durian has approximately 46,000 genes, nearly double those found in humans.