Articles tagged with Cancer Screening
A recent study reveals that sexual minority individuals are less likely to undergo cervical cancer screening, with Hispanic individuals facing the most significant disparities. The analysis of 2015–2018 data from the National Health Interview Survey found that white sexual minority participants and Hispanic sexual minority participants...
New research suggests that PSA screening has remarkably favorable tradeoffs, particularly for Black men, who disproportionately bear the burden of prostate cancer mortality and morbidity. The study's findings support the use of PSA screening for high-risk groups, including Black men, and highlight the need to revise clinical guidelines...
Research suggests that PSA screening can prevent a significant number of prostate cancer deaths, with lower numbers than previously estimated. The study's findings support the benefits of PSA screening, especially for young healthy men and Black men, who have historically been underrepresented in clinical trials.
Adults aged 45-64 experienced a nearly doubled rate of esophageal cancer and a 50% increase in Barrett's esophagus between 2012 and 2019. Researchers recommend more frequent screening for middle-aged patients with multiple risk factors.
Patients with stage II/III esophageal cancer who received delayed surgery had a relative survival rate that was almost half that of patients who underwent early surgery. Early-stage cancer patients did not experience significant differences in survival rates between those who received immediate versus delayed surgery.
Researchers developed an algorithm to quickly identify two cancer drugs that work well together, reducing testing time from three years to eight weeks. The new method uses gene expression data to prioritize potential combinations and has been confirmed in lab tests.
Cancer incidence is projected to double in SSA by 2040, with 1.4 million cases per year expected without rapid interventions. Women are more affected by cancer than men in the region, with breast and cervical cancers among the most common types.
A new study from Massachusetts General Hospital found that starting endoscopic screening at age 45 can significantly reduce the risk of colorectal cancer (CRC) in women. The study included 111,801 women and showed a 50-60% lower risk of CRC among those who started screening at this age.
Canada's cancer rates are declining overall, but new cases and deaths are on the rise due to an aging population and growing numbers. Despite this, efforts in cancer prevention, screening, early detection, and treatment have led to improved survival rates for those diagnosed with cancer.
A new study published in the Journal of Medical Screening found that over half of eligible women (51.4%) prefer self-sampling for cervical cancer screening, as it addresses concerns about embarrassment and provides more flexibility. The study also suggests that many regular screeners may switch to self-sampling if offered the option.
A new study published in Neurology found that women with multiple sclerosis (MS) are less likely to have breast cancer detected through routine screenings, despite being twice as likely to have colorectal cancer detected at an early stage. The researchers also found a higher rate of disability among MS patients, which may affect their ...
A new study suggests that while breast density knowledge may be increasing due to existing state laws, there is still room for improvement. The study found that most women with non-dense breasts did not correctly know their own density, and that lower education was associated with a lower chance of accurately knowing one's own density.
Research from Weill Cornell Medicine found that less prostate cancer screening has reduced overdiagnosis, but increased incidence of high-grade and metastatic disease. The study analyzed over 438,000 men with newly diagnosed prostate cancer between 2010 and 2018.
The ESMO Breast Cancer Congress 2022 event will present more than 200 studies on various aspects of breast cancer, including new treatments and innovative clinical practices. The congress will be held onsite in Berlin, Germany, and online, offering a platform for breast cancer specialists to share knowledge and improve patient outcomes.
A study published in Gastroenterology found that artificial intelligence reduced the rate of missed precancerous polyps in colorectal cancer screening by twofold compared to standard colonoscopy. The AI detection method identified smaller, flatter polyps and improved false negative rates.
A recent study by Cathy Bradley found that Medicaid patients with continuous coverage have better cancer survival rates compared to those without. Conversely, screening programs for low-income women may not be as effective as general insurance coverage.
Researchers identified rural Georgia counties with high mortality rates from breast, prostate, colorectal, and lung cancer. These hotspots were concentrated in the eastern Piedmont to southern Coastal Plain regions, as well as southwestern and northern rural areas.
Researchers identified clofarabine as a promising compound with inhibitory effects on bladder cancer cells, including urothelial carcinoma and sarcomatoid carcinoma. The study suggests potential for clinical trials to treat metastatic bladder cancer patients who cannot receive traditional cisplatin-based therapy.
A study suggests that accounting for genetic factors causing normal variations in PSA levels could improve the accuracy of prostate cancer detection. By analyzing data from over 95,000 men, researchers identified a polygenic score that accounted for 7.3-8.7% of variation in baseline PSA levels and was not associated with prostate cancer.
Patients with mild to moderate kidney disease and kidney transplant recipients had a higher risk of cancer. They also faced a higher risk of dying from cancer, particularly from cancers such as bladder, kidney, and multiple myeloma, compared to those with normal kidney function.
Researchers found a steady decline in annual mammography use by breast cancer survivors between 2009 and 2016, with the largest decrease seen among younger patients. The study highlights the importance of reinforcing the significance of annual mammograms for breast cancer survivors.
Researchers found that modeling studies have been assuming colonoscopies are more accurate than they really are, detecting fewer small adenomas. However, colonoscopy still appears effective in finding precursors of cancer.
Researchers discovered that a genetic mutation causing odd-shaped nuclei may lead to earlier diagnosis and treatment of certain leukemias. The study found that the loss of nuclear Lamin B1 induces defects in nuclear morphology and genome instability, setting the stage for cancer.
The American Association for Cancer Research (AACR) has announced the recipients of its 2022 Scientific Achievement Awards and Lectureships, recognizing Tony Hunter, Christina Curtis, John E. Dick, Kevan M. Shokat, and Lee M. Ellis for their groundbreaking contributions to cancer research.
The NCCN Annual Conference focuses on the cancer patient journey, featuring state-of-the-art practice algorithms, updates to clinical guidelines, and new therapies. Leading experts present treatment recommendations for various cancer types, including breast, colorectal, and lung cancer.
A new study finds that lung cancer screening is less common among those with poor health, with racial and ethnic disparities evident despite potential benefits. Non-Hispanic Black individuals are nearly half as likely to report lung cancer screening as non-Hispanic White individuals.
The Victoria's Secret Global Fund for Women's Cancers has awarded five female researchers for their groundbreaking work on breast and gynecologic cancers. The recipients will receive a $100,000 honorarium and be invited to participate in a broader women's cancers grant program.
The study reveals a narrowing gap between cancer profiles in China and the USA, with converging trends in lung, breast, and colorectal cancers. China's cancer burden is expected to rise, while the US has seen reduced rates since the 1990s due to effective prevention strategies.
Lung cancer screening in the US has been associated with increased early detection of non-small cell lung cancer and improved survival rates. However, disparities in access to screening remain, with economically deprived areas and racial/ethnic minority groups showing reduced benefits.
A machine-learning algorithm detected potential signs of colorectal cancer in high-risk patients who missed routine screenings. The algorithm identified patients as high-risk by analyzing age, gender, and recent CBC results, and subsequent screenings showed significant findings in 70% of the flagged group.
A new study reveals AI's potential in reducing workload for radiologists and improving breast cancer detection rates, with favorable histopathologic characteristics associated with better prognosis. The technology has shown encouraging results for cancer detection, but evidence related to its use in real screening settings is limited.
A study published in JAMA Network Open found that half of all women will experience at least one false positive mammogram over a decade of annual breast cancer screening with 3D mammography. The risk of false positives is lower for women screened every other year, and non-dense breasts also show a lower false positive risk.
A consensus reached by a lung clinical community highlighted international disparities in management and outcomes of patients with lung cancer. The roadmap provides key actions to homogenize practices, facilitate earlier diagnosis, and offer equitable access to care.
A new study reveals that the COVID-19 pandemic has led to significant declines in cancer screening rates across the US, particularly for colorectal, cervical, breast, and lung cancers. The American Cancer Society's National Consortium has announced nine recommendations to increase cancer screening rates and improve quality care.
A novel screening platform has successfully detected over 95% of stage 1 pancreatic cancers using artificial intelligence-enabled protein marker analysis, outperforming current liquid biopsy tests in accuracy. This technology holds promise for early cancer detection and reducing mortality from this deadly disease.
HPV vaccine approval led to increased screening and vaccination rates, resulting in a decrease in HPV-associated cancer cases. The study found significant declines in cervical, anal, and oropharyngeal cancers during this period.
The European Lung Cancer Congress 2022 focused on the latest advancements in lung cancer treatment, including personalized strategies for better patient care. The congress also explored emerging therapies and molecular sub-types to enhance precision medicine.
The Southeastern Consortium for Lung Cancer Health Equity aims to address disparities in lung cancer screening among racially and ethnically diverse populations. Researchers will develop more precise methods for identifying those at highest risk of lung cancer diagnoses.
A study from Keck Medicine of USC found a significant increase in metastatic prostate cancer cases among men 45 and older, coinciding with the end of routine screenings. The incidence rate rose by 41% in men 45-74 and 43% in men 75 and older.
Research found a significant drop in new cancer diagnoses during the COVID-19 pandemic, particularly for screening cancers like breast, cervical, and colorectal cancer. The study estimates around 12,600 cancers went undetected between March 2020 and September 2020.
A recent study by City of Hope researchers highlights the limitations of Signatera, a popular liquid biopsy test for detecting colorectal cancer recurrence. The study found that standard-of-care CT scan plus CEA blood draw test was more effective in identifying early disease recurrence.
A new study developed an algorithm estimating a person's risk of developing prostate cancer based on age and two prostate cancer markers. The approach was found to reduce the number of false positives by three quarters compared to a standard PSA test while catching the same proportion of cancers, making screening safer and more accurate.
A meta-analysis of 280,660 cases of colorectal cancer and 14,139 cases of adenoma found that taller individuals have a higher risk of developing colorectal cancer and precancerous colon polyps. The study suggests that adults over 4 inches (10 cm) above the average U.S. height may be at increased risk.
A new study found that cervical cancer incidence is increasing in low-income US counties, while plateauing in high-income counties. The study analyzed data from 2000 to 2018 and estimated trends by county-level household income and smoking prevalence.
The Cancer Prevention & Research Institute of Texas has awarded a grant extension to Dr. Rakhshanda Rahman, allowing her to provide no-cost mammograms and Pap smears to underinsured and uninsured women in the Permian Basin. The program aims to address high cervical cancer incidence and mortality rates in West Texas.
A modeling study suggests that breast cancer overdiagnosis may occur in about 15% of screen-detected cases, rather than the estimated 30%. This could spare around 25,000 women unnecessary treatment. Researchers used data from the Breast Cancer Surveillance Consortium to estimate the rate of overdiagnosis.
Scientists have discovered a new therapeutic approach to aid the immune system in fighting cancer, offering hope for better solutions for patients. Researchers found that blocking the EP4 molecule can 'free' the immune system and restore its cancer-fighting functions.
Researchers developed a new deep learning algorithm that allows for real-time reconstruction of images combining optical and magnetic resonance imaging data. The algorithm, Z-Net, enables faster image generation and can be trained with simulated data, improving breast cancer detection.
A regionwide, structured colorectal cancer screening program eliminated disparities in colorectal cancer death rates between Black and white Kaiser Permanente members. Organized screening outreach markedly increased screening rates and led to significant decreases in incidence and death rates.
Annual MRI screenings starting at ages 30-35 may reduce breast-cancer mortality by more than 50% among women who carry certain genetic changes in three genes. The predictions involve pathogenic variants in ATM, CHEK2 and PALB2 genes – which collectively are as prevalent as the much-reported BRCA1/2 gene mutations.
A recent study published in JAMA Network Open found that the COVID-19 pandemic led to fewer early-stage and more late-stage breast cancer diagnoses. Researchers at UC San Diego Health surveyed patients with breast and colorectal cancers in 2019 and 2020, finding a significant increase in stage IV diagnoses.
Researchers at Mayo Clinic Cancer Center developed a machine learning algorithm that integrates genetic data from over 5,000 patients to predict patient benefit from chemotherapy and immunotherapy. A 32-gene molecular signature was identified, providing prognostic information and predicting patient response to immunotherapy.
New studies from Michigan Medicine researchers aim to remove financial barriers for patients who receive abnormal test results, enabling them to complete the diagnostic process. The findings suggest that removing cost barriers could save lives by increasing screening uptake, particularly among women and underserved populations.
A comprehensive analysis of over 2,200 patients in Europe reveals the complexity of cholangiocarcinoma, a rare cancer often diagnosed at an advanced stage. The study highlights the need for education programs to raise awareness and improve early diagnosis, survival, and quality of life.
Researchers have designed a tiny and flat antenna for receiving and transmitting terahertz signals, enabling the miniaturization of THz devices. The new design integrates the antenna with the system, eliminating the need for bulky silicon lenses and reducing optical power required.
A study found that risks of preterm birth, infant sepsis, and other adverse outcomes associated with CIN-3 treatment have decreased over time. Pregnancies after CIN-3 treatment should be managed as 'high risk' to reduce these risks.
A culturally tailored patient navigation program improved the rate of colorectal cancer screening among Hispanic adults, reducing historical gender disparities. The program's colonoscopy completion rate was 85%, with no difference between males and females.
A new study found nearly 17% of cancer survivors experience moderate or increased housing insecurity, complicating disease management and healthcare navigation. Housing insecurity also correlates with lower household income, educational attainment, and being Black.
Researchers in Japan evaluated the cost-effectiveness of adding dipstick hematuria screening to a mass health check-up program. The study found that including routine testing for hematuria would promote early detection and treatment, leading to cost savings and improved patient outcomes. This cost-effective approach has the potential t...
The Purdue Research Foundation Office of Technology Commercialization has awarded more than $143,000 to three projects led by researchers in the College of Agriculture, Engineering and Veterinary Medicine. Guri Johal is developing a corn variant that could impact worldwide corn production with Trask funds supporting his project on clon...