Articles tagged with Cancer Screening
USCF researchers have developed a new approach called CAR Pooling to compare different re-engineered T cells with varying molecular features. The screen revealed new and surprising receptors that make these therapeutic cells more powerful, promising a better treatment for blood cancers.
A study found that top YouTube and TikTok videos on prostate cancer screening recommendations have low to moderate quality consumer health information. Black and Hispanic representation was underrepresented in most videos, and high-risk racial groups were not discussed adequately.
A study analyzing 16,083 colorectal biopsies found that 2.65% of rectal adenocarcinoma patients have mismatch repair deficiency, challenging earlier estimates. The analysis also highlighted the importance of screening at all ages for this condition.
Research at Linköping University suggests that dense breasts have unique biological characteristics that promote cancer growth, leading to a fivefold increased risk. The study used MRI and microdialysis techniques to measure proteins in breast tissue, finding elevated levels of inflammatory markers and growth factors.
Researchers from Brigham and Women's Hospital found that circulating tumor HPV DNA levels are linked to lymph node presence, making the test less effective for screening. This limits the use of ctHPV DNA testing for early diagnosis and treatment of oropharynx cancer.
The Institute of Human Virology has received $7.5 million in NCI grants to combat lung cancer and anal precancer in Botswana and Nigeria, respectively. The studies will utilize existing HIV treatment infrastructure to reach at-risk populations and contribute to global cancer control.
Researchers at Tokyo Medical and Dental University developed a new technique to detect breast cancer-related markers using transistors, offering a less invasive method for monitoring patients. The system successfully detected epidermal growth factor receptor expression on cancer cells.
A recent investigation by The BMJ reveals dozens of UK companies offering private blood tests with misleading claims, contradicting official medical guidance and potentially harming individuals. Experts argue for regulation to protect consumers and prevent unnecessary costs for the NHS.
A new project aims to create more race-inclusive AI in medicine by developing a distributed, inclusive data collection and learning framework that relies on smartphone apps. The framework uses federated learning, which allows models to be trained on device data while protecting user privacy.
A large-scale analysis of VA medical centers found that facilities with lower yearly PSA screening rates had higher rates of metastatic prostate cancer in subsequent years. The study supports the benefits of prostate cancer screening in reducing metastatic prostate cancer risk, particularly for high-risk groups like Black patients.
USC Norris Comprehensive Cancer Center is partnering with the Chinatown Service Center to address disparities in cervical cancer screening and treatment. The partnership aims to optimize access, shorten diagnosis-to-treatment timeframes, and enhance quality of care for Chinese and Latina women in Los Angeles.
A study of over 4 million claims found that Black women had less access to new mammography technology, even when receiving mammograms at the same institution. The disparities in digital breast tomosynthesis use among Black and white women began to subside after 2016.
A study published in the Journal of Medical Screening found that pre-booked appointments increased breast cancer screening attendance by 53.1%, compared to 60.6% for timed appointments in London between September 2020 and March 2021.
The American College of Physicians recommends increasing funding for health services and prioritizing health promotion in Indigenous communities. Community-driven public policy is also necessary to address historical trauma, social determinants of health, and inadequate access to healthcare services.
Scientists at IRB Barcelona and the PCCB have created a genetically tractable model of Ewing sarcoma using Drosophila flies expressing a mutant version of the human oncogene EWS-FLI. This model allows for the identification of critical proteins required for EWS-FLI's oncogenic function and potential therapeutic targets.
A study published in the Journal of Thoracic Oncology suggests that expanding low-dose CT screening eligibility criteria can increase access to screening for women and Black persons. The research found that widening eligibility guidelines reduced smoking exposure criteria increased lung cancer diagnoses among these groups.
Researchers developed an AI algorithm to assess retinal vasculature, predicting cardiovascular disease and death. The model captured half to two-thirds of circulatory disease deaths in those most at risk, outperforming traditional risk frameworks.
Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed a novel, cost-effective approach to detect cancer at its early stages using cell-free DNA in blood samples. Their method, cfMethyl-seq, has shown high accuracy and potential for accurate early diagnosis of certain cancers from a single blood test.
The TTUHSC team will provide no-cost colorectal cancer screening and colonoscopies to underinsured and uninsured people living in South Plains region counties. The FIT-STOP program aims to find signs of early-stage colorectal cancer to prevent treatment needs, leveraging existing relationships with partners.
A UTHealth Houston study found regional disparities in cancer screening rates tied to social vulnerability, with lower rates in more vulnerable counties. The study analyzed 3,141 US counties and discovered significant differences in breast, cervical, and colorectal cancer screenings.
A study of 3,141 US counties found that counties with higher social vulnerability had lower rates of recommended breast, cervical, and colorectal cancer screenings. The findings suggest that addressing social determinants of health may be crucial for improving cancer screening rates.
A cohort study found that endoscopists performing colonoscopies in FIT-based screening programs should aim for markedly higher ADRs compared to primary colonoscopy screening. The study suggests that high ADRs are associated with lower colorectal cancer incidence and mortality. Researchers recommend using ADR targets, including differen...
A mortality prediction model for older adults with dementia can guide discussions about financial resources, treatment preferences, and reduce unnecessary medical interventions. The model considers factors such as age, sex, body mass index, chronic conditions, and ability to perform daily activities.
The author suggests that individuals at average risk between 45 and 49 years old should consider non-invasive screening alternatives, such as fecal immunochemical tests or stool DNA testing. This approach would benefit others who need more invasive screening resources and reduce the strain on colonoscopy services.
A study found that trained radiographers perform as well as radiologists in key areas of double reading mammograms, improving cancer detection rates. The results suggest that focused training and experience are key factors in reader performance, not just medical degree or broad radiology education.
Researchers at Duke University developed nanorattles that amplify signals from separate biomarkers, allowing for accurate detection of head and neck cancers without biopsies. The technology uses machine learning algorithms to tease apart multiple biomarker signals, making it possible to target multiple diseases simultaneously.
A new blood test has shown promising results for detecting multiple types of cancer from tumor DNA in the blood, enabling early detection and potentially changing cancer screening practices. The test's accuracy and effectiveness have been demonstrated in a recent study, with high sensitivity and specificity rates.
Late-breaking results at ESMO Congress 2022 reveal a strong association between air pollution and non-small cell lung cancer, with exposure to particulate matter linked to increased risk. The research underscores the need for environmental sustainability in oncology, particularly in cancer prevention and early detection.
A Cornell-led group of researchers has developed a search method that identifies terms similar to cancer screening tests in colloquial language, expanding conventional data-collection pipelines. The technique was applied to YouTube searches, retrieving relevant videos using words semantically close to the main term.
A large study found that obstructive sleep apnea is independently associated with an increased risk of cancer. Patients with more severe OSA were also at a greater risk of developing blood clots. Additionally, a second study linked OSA to a decline in mental processing powers, particularly in the elderly.
Advanced cervical cancer rates have been rising in the US, with a significant increase among White women and higher prevalence among Black women, particularly those in their mid-to-late 50s. The study found that obesity and older age at first birth may contribute to the rise in this type of cervical cancer.
Researchers at Queen Mary University of London have found that increasing the blood level at which faecal blood testing triggers a colonoscopy invitation can reduce lives lost from bowel cancer. This approach is more effective than changing the gap between screening invitations.
Scientists have developed a smart contact lens that can capture and detect exosomes, nanometer-sized vesicles found in bodily secretions, which hold promise for cancer diagnostics. The lens was designed to bind to antibodies capturing exosomes found in tears, offering a potential platform for non-invasive cancer screening.
Researchers found lower stages of breast cancer in women aged 40-49 compared to those aged 50-59, with a significant decrease in stage 4 cases. This suggests that early detection through regular mammograms can lead to better health outcomes and survival rates.
A new nomogram has been developed to assess lung cancer risk in female non-smokers in China, using data from 151,834 patients. The model identified five independent risk factors, including age, chronic respiratory disease, and menopause, and showed good predictive discrimination.
A recent study published by Wiley suggests that biological sex differences are the primary reason for higher cancer rates in men compared to women. The study analyzed data from 171,274 males and 122,826 females aged 50-71 years and found that incidence was lower in men only for thyroid and gallbladder cancers.
A recent clinical trial led by Massachusetts General Hospital validated a strategy for increasing shared decision-making about colorectal cancer screening in older patients. Brief physician training plus reminders resulted in patients reporting higher quality conversations, with more discussing their preferences and having more options...
Annual PSA screening associated with reduced risk of prostate cancer-specific mortality among non-Hispanic Black men. The study suggests that annual screening may be particularly important for Black men, reducing their risk compared to less frequent screening.
A new study by the American Cancer Society found that older age and smoking are the most important risk factors associated with a higher relative and absolute five-year risk of developing any cancer. The study analyzed data from two large cohort studies and identified excess body fatness, family history of cancer, and other factors as ...
The NHS Breast Screening Programme is associated with modest overdiagnosis of breast cancer, estimated at 3.7% of screen detected cancers. However, the benefits of screening in preventing deaths from breast cancer outweigh this risk, according to a recent study.
Researchers used radiomics-based machine learning models to detect pancreatic cancer on prediagnostic CT scans, identifying it up to 386 days before clinical diagnosis. The AI model showed high accuracy and specificity, with a range of 94-98%, and was unaffected by image variations.
A new study found that most patients with pancreatic cancer diagnosed through regular screenings had early-stage disease, leading to long-term survival. The study suggests that surveillance programs can help detect precancerous conditions and cancers early, when they are most treatable.
A national, randomized trial found that intensive telephone-based cessation counseling resulted in a two-fold greater cigarette quit rate than minimal counseling and nicotine replacement. The study also showed significant benefits for people with higher nicotine dependence and those who engaged more with the counseling.
A systematic review and meta-analysis of 39 publications found a global association between COVID-19 measures and reduced breast, colorectal, and cervical cancer screenings. This could lead to an increase in avoidable cancer deaths.
Researchers developed a nomogram to predict anal cancer risk in persons with HIV infection, highlighting increased risk among those living with the virus. The model estimates quantitative risk based on patient characteristics, informing screening decisions.
A study found that younger U.S. adults are less likely to be screened for colorectal cancer despite being eligible under new guidelines, with greater disparities observed across race, ethnicity, income, education, and insurance coverage. Screening participation increased over time but was smallest among individuals age 50-54.
A large clinical trial found treating anal precancerous lesions reduces the risk of developing anal cancer in people with HIV by 57%. The study highlights the need for screening and treating high-grade squamous intraepithelial lesions (HSIL) as the standard of care for older HIV+ individuals.
Researchers found eligible younger Americans (45-54) are less likely to meet recommended colorectal cancer screening guidelines due to work, family, insurance, and healthcare barriers. These disparities may worsen as the age group is expanded under new USPSTF recommendations.
A recent survey revealed significant gaps in cancer screening among women aged 50-64, with rates as low as 50% for colorectal cancer and 46.5% for both cancers. The study found that patient-centered approaches to screening can facilitate timely testing and management of abnormal results.
A study published in JAMA Oncology found significant disparities in breast biopsy delays among non-white women, with Black women experiencing the longest delays. Structural racism within healthcare facilities and screening site-specific factors contribute to these disparities.
The US Preventive Task Force's revised guidelines have increased the proportion of African Americans screened for lung cancer, a move expected to lead to more lives saved. The study, published in JAMA Network Open, analyzed data from over 800 patients and found that those eligible under the new criteria had a significantly higher rate ...
A recent study found that certain bacteria species in the gut are associated with a higher risk of colorectal cancer in younger populations. The research suggests that dietary patterns high in processed meats, low-calorie drinks, and liquor may contribute to this increased risk.
The American Gastroenterological Association has released a series of evidence-based position statements guiding the creation of a national colorectal cancer screening approach. The goal is to eliminate barriers and reduce mortality by ensuring equitable access to CRC screening programs for all individuals.
A study found that the COVID-19 pandemic led to a significant drop in cancer screenings for breast, cervical, and colorectal cancers in 2020. The number of women who reported having recent breast cancer or cervical cancer screenings dropped by 6% and 11%, respectively.
A national survey study found that colorectal cancer screening increased via stool testing while colonoscopy decreased during the pandemic. Breast and cervical cancer screenings also saw modest declines.
The new guidelines expand indication for screening to all with BRCA 1/2 gene variations, increasing chances of early detection and treatment. The guidelines also acknowledge potential downsides of screening, including false-positive results and encourage careful patient counseling.
A study of 1.3 million women in England found that screening every five years is as effective as three-year intervals for those with a negative HPV screen, and may even prevent more cancers. The study provides reassurance to women aged 24-49 who test negative for HPV.
A minimally invasive device combined with molecular biomarkers has shown a 90% success rate in detecting esophageal squamous cell carcinoma, the predominant subtype of esophageal cancer. Early detection is crucial to improve survival rates, as symptoms often become apparent too late for effective treatment.
According to a study published at the ATS 2022 international conference, nearly half of patients with abnormal findings in lung cancer screening experienced delays in following up. The median delay time was 91 days, with current smokers having longer delays than former smokers.
A recent study reveals that sexual minority individuals are less likely to undergo cervical cancer screening, with Hispanic individuals facing the most significant disparities. The analysis of 2015–2018 data from the National Health Interview Survey found that white sexual minority participants and Hispanic sexual minority participants...