Articles tagged with Cancer Screening
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A comprehensive analysis of over 100,000 colorectal cancer cases identified 100 new genetic risk factors strongly linked with the disease. These findings could help clinicians determine who's at highest risk for early detection and potentially identify candidates for preventive treatments.
Despite decreases in some high-income countries, the global cervical cancer burden remains high due to inadequate screening and vaccination programs in low- and middle-income countries. The study highlights the need for scaling up HPV vaccination and screening efforts globally to achieve the WHO's 2030 elimination target.
Researchers found that lncRNA MVIH is overexpressed in cervical cancer tumors and associated with younger age, lymph node metastasis, tumor invasion depth, and squamous cell type. This suggests its potential as a diagnostic biomarker for cervical cancer.
A new diagnostic pathway for prostate cancer reduces the number of harmless tumors found during screening, halving the risk of overdiagnosis. This strategy involves using MRI to guide targeted tissue sampling, reducing the need for unnecessary biopsies and associated complications.
Researchers analyzed data from over 80,000 primary care physicians and found no clear connection between MIPS scores and clinical performance. Doctors with low MIPS scores performed worse on some process measures but better on others, suggesting that the system may prioritize paperwork over patient outcomes.
NUS researchers have developed a low-cost, non-invasive cancer testing method that sequences clinical samples heated to isolate cancer-specific signatures in patient blood. The Heatrich-BS assay has high sensitivity comparable to gold standard CT scans and costs around US$35 from start to finish.
A study found that concerns about colonoscopy, lack of opportunity to discuss next steps with a medical provider, and assumptions about personal risk are common reasons patients don't follow up after a positive at-home test. Researchers also developed two simple risk measurement tools to predict COVID-19 mortality rates, which could he...
A study found that high deductible health plans can lead to a decrease in the number of women undergoing indicated breast imaging, particularly those with lower incomes and education levels. The researchers hope their findings will inform efforts to remove financial barriers to care and improve health outcomes for vulnerable populations.
A nationwide questionnaire in Dutch colorectal cancer screening found that concerns about colonoscopy, lack of provider discussion, and personal risk perceptions are common reasons for not following up. Personalized screening counseling and family practitioner involvement may help increase follow-up rates.
A new study found that a three-year interval between screenings using non-invasive multi-target stool DNA testing is clinically appropriate for individuals with average risk of colorectal cancer. The study, led by Thomas F. Imperiale, M.D., identified no colorectal cancers in participants after an initial negative test.
A new machine learning fusion model has been developed to diagnose ovarian cancer more accurately by combining ultrasound and photoacoustic tomography imaging. The model achieved an accuracy of 90% in detecting ovarian lesions, outperforming previous methods.
Researchers developed a deep learning model that uses a single chest X-ray to predict the 10-year risk of death from cardiovascular disease. The model performed similarly to established clinical standards and provided incremental value in predicting major adverse cardiac events.
A new study published in JAMA Internal Medicine suggests that more public health data is needed on the utilization of cervical cancer screening-associated services among older women. The analysis showed that over 1.3 million women received cervical cancer screening-associated services after age 65, with costs exceeding $83 million.
A study led by Dr. Ashish Deshmukh finds a significant increase in anal cancer incidence among women and men over 50 years old in the Midwestern and Southeastern states, with HPV infections and smoking identified as key risk factors.
University of Copenhagen researchers made a groundbreaking discovery about the mammalian brain, finding that a vital enzyme that enables brain signals is switching on and off at random intervals. This challenges the long-held assumption that these enzymes are active at all times to convey essential signals continuously.
A large-scale international study found that patients diagnosed with lung cancer at an early stage via CT screening have a 20-year survival rate of 80 percent. This is compared to the average five-year survival rate for all lung cancer patients, which is 18.6 percent.
A large-scale study found that low-dose CT screening increases the long-term survival rate of lung cancer patients by identifying early-stage cancers. The 20-year survival rate for participants diagnosed with early-stage lung cancer was 80%, with higher rates for those with solid nodules and clinical Stage IA lung cancers.
Researchers found a 3% per year increase in cervical cancer incidence in women in their early 30s, starting from 2012, and an increase in both localized and regional disease. The study suggests that improved screening rates are needed to address the rising incidence.
Population-based cancer screening rates declined during the pandemic, only to recover rapidly in initial stages; however, long-term follow-up reveals ongoing gaps in preventive care. The study suggests that prolonged disruptions in screening can have lasting effects on public health.
The ESMO Asia Congress 2022 will focus on the latest scientific and clinical advances in oncology, with a special emphasis on the Asia-Pacific region. Media representatives can register for coverage through the official media registration form.
A large observational study found that women diagnosed with benign breast disease through screening are at a higher risk of developing breast cancer in the long term. The risk persisted for at least two decades and was found to be significantly higher among women with benign breast disease compared to those without.
A national quality improvement project led by the American College of Surgeons restored cancer screenings to pre-pandemic levels and increased additional screening tests. The initiative helped accredited programs increase screening rates by implementing evidence-based interventions and achieved a minimum of 10% growth in screening.
A study by Leiden University Medical Center found six proteins in blood samples that were altered one to two years before a breast cancer diagnosis. The researchers believe these proteins could be used to develop a blood test for early detection of breast cancer in high-risk women.
A new model predicts individual breast cancer risk based on ten known risk factors, allowing for tailored screening strategies. The study found that the risk of developing breast cancer ranges from 0.22% to 7.43%, with some factors, such as exercise, having a greater impact than previously thought.
A study of 11,945 people found that those with type 2 diabetes are more likely to be diagnosed with advanced cancer if the condition is not screened for routinely. Researchers identified a 26% increased risk of metastasis in patients with pre-existing type 2 diabetes.
USCF researchers have developed a new approach called CAR Pooling to compare different re-engineered T cells with varying molecular features. The screen revealed new and surprising receptors that make these therapeutic cells more powerful, promising a better treatment for blood cancers.
A study found that top YouTube and TikTok videos on prostate cancer screening recommendations have low to moderate quality consumer health information. Black and Hispanic representation was underrepresented in most videos, and high-risk racial groups were not discussed adequately.
A study analyzing 16,083 colorectal biopsies found that 2.65% of rectal adenocarcinoma patients have mismatch repair deficiency, challenging earlier estimates. The analysis also highlighted the importance of screening at all ages for this condition.
Researchers at Tokyo Medical and Dental University developed a new technique to detect breast cancer-related markers using transistors, offering a less invasive method for monitoring patients. The system successfully detected epidermal growth factor receptor expression on cancer cells.
Research at Linköping University suggests that dense breasts have unique biological characteristics that promote cancer growth, leading to a fivefold increased risk. The study used MRI and microdialysis techniques to measure proteins in breast tissue, finding elevated levels of inflammatory markers and growth factors.
Researchers from Brigham and Women's Hospital found that circulating tumor HPV DNA levels are linked to lymph node presence, making the test less effective for screening. This limits the use of ctHPV DNA testing for early diagnosis and treatment of oropharynx cancer.
The Institute of Human Virology has received $7.5 million in NCI grants to combat lung cancer and anal precancer in Botswana and Nigeria, respectively. The studies will utilize existing HIV treatment infrastructure to reach at-risk populations and contribute to global cancer control.
A recent investigation by The BMJ reveals dozens of UK companies offering private blood tests with misleading claims, contradicting official medical guidance and potentially harming individuals. Experts argue for regulation to protect consumers and prevent unnecessary costs for the NHS.
A new project aims to create more race-inclusive AI in medicine by developing a distributed, inclusive data collection and learning framework that relies on smartphone apps. The framework uses federated learning, which allows models to be trained on device data while protecting user privacy.
A large-scale analysis of VA medical centers found that facilities with lower yearly PSA screening rates had higher rates of metastatic prostate cancer in subsequent years. The study supports the benefits of prostate cancer screening in reducing metastatic prostate cancer risk, particularly for high-risk groups like Black patients.
USC Norris Comprehensive Cancer Center is partnering with the Chinatown Service Center to address disparities in cervical cancer screening and treatment. The partnership aims to optimize access, shorten diagnosis-to-treatment timeframes, and enhance quality of care for Chinese and Latina women in Los Angeles.
A study published in the Journal of Medical Screening found that pre-booked appointments increased breast cancer screening attendance by 53.1%, compared to 60.6% for timed appointments in London between September 2020 and March 2021.
A study of over 4 million claims found that Black women had less access to new mammography technology, even when receiving mammograms at the same institution. The disparities in digital breast tomosynthesis use among Black and white women began to subside after 2016.
The American College of Physicians recommends increasing funding for health services and prioritizing health promotion in Indigenous communities. Community-driven public policy is also necessary to address historical trauma, social determinants of health, and inadequate access to healthcare services.
Scientists at IRB Barcelona and the PCCB have created a genetically tractable model of Ewing sarcoma using Drosophila flies expressing a mutant version of the human oncogene EWS-FLI. This model allows for the identification of critical proteins required for EWS-FLI's oncogenic function and potential therapeutic targets.
A study published in the Journal of Thoracic Oncology suggests that expanding low-dose CT screening eligibility criteria can increase access to screening for women and Black persons. The research found that widening eligibility guidelines reduced smoking exposure criteria increased lung cancer diagnoses among these groups.
Researchers developed an AI algorithm to assess retinal vasculature, predicting cardiovascular disease and death. The model captured half to two-thirds of circulatory disease deaths in those most at risk, outperforming traditional risk frameworks.
Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed a novel, cost-effective approach to detect cancer at its early stages using cell-free DNA in blood samples. Their method, cfMethyl-seq, has shown high accuracy and potential for accurate early diagnosis of certain cancers from a single blood test.
The TTUHSC team will provide no-cost colorectal cancer screening and colonoscopies to underinsured and uninsured people living in South Plains region counties. The FIT-STOP program aims to find signs of early-stage colorectal cancer to prevent treatment needs, leveraging existing relationships with partners.
A UTHealth Houston study found regional disparities in cancer screening rates tied to social vulnerability, with lower rates in more vulnerable counties. The study analyzed 3,141 US counties and discovered significant differences in breast, cervical, and colorectal cancer screenings.
A study of 3,141 US counties found that counties with higher social vulnerability had lower rates of recommended breast, cervical, and colorectal cancer screenings. The findings suggest that addressing social determinants of health may be crucial for improving cancer screening rates.
A cohort study found that endoscopists performing colonoscopies in FIT-based screening programs should aim for markedly higher ADRs compared to primary colonoscopy screening. The study suggests that high ADRs are associated with lower colorectal cancer incidence and mortality. Researchers recommend using ADR targets, including differen...
A mortality prediction model for older adults with dementia can guide discussions about financial resources, treatment preferences, and reduce unnecessary medical interventions. The model considers factors such as age, sex, body mass index, chronic conditions, and ability to perform daily activities.
The author suggests that individuals at average risk between 45 and 49 years old should consider non-invasive screening alternatives, such as fecal immunochemical tests or stool DNA testing. This approach would benefit others who need more invasive screening resources and reduce the strain on colonoscopy services.
A study found that trained radiographers perform as well as radiologists in key areas of double reading mammograms, improving cancer detection rates. The results suggest that focused training and experience are key factors in reader performance, not just medical degree or broad radiology education.
Researchers at Duke University developed nanorattles that amplify signals from separate biomarkers, allowing for accurate detection of head and neck cancers without biopsies. The technology uses machine learning algorithms to tease apart multiple biomarker signals, making it possible to target multiple diseases simultaneously.
A new blood test has shown promising results for detecting multiple types of cancer from tumor DNA in the blood, enabling early detection and potentially changing cancer screening practices. The test's accuracy and effectiveness have been demonstrated in a recent study, with high sensitivity and specificity rates.
Late-breaking results at ESMO Congress 2022 reveal a strong association between air pollution and non-small cell lung cancer, with exposure to particulate matter linked to increased risk. The research underscores the need for environmental sustainability in oncology, particularly in cancer prevention and early detection.
A Cornell-led group of researchers has developed a search method that identifies terms similar to cancer screening tests in colloquial language, expanding conventional data-collection pipelines. The technique was applied to YouTube searches, retrieving relevant videos using words semantically close to the main term.
A large study found that obstructive sleep apnea is independently associated with an increased risk of cancer. Patients with more severe OSA were also at a greater risk of developing blood clots. Additionally, a second study linked OSA to a decline in mental processing powers, particularly in the elderly.
Advanced cervical cancer rates have been rising in the US, with a significant increase among White women and higher prevalence among Black women, particularly those in their mid-to-late 50s. The study found that obesity and older age at first birth may contribute to the rise in this type of cervical cancer.
Researchers at Queen Mary University of London have found that increasing the blood level at which faecal blood testing triggers a colonoscopy invitation can reduce lives lost from bowel cancer. This approach is more effective than changing the gap between screening invitations.
Scientists have developed a smart contact lens that can capture and detect exosomes, nanometer-sized vesicles found in bodily secretions, which hold promise for cancer diagnostics. The lens was designed to bind to antibodies capturing exosomes found in tears, offering a potential platform for non-invasive cancer screening.
Researchers found lower stages of breast cancer in women aged 40-49 compared to those aged 50-59, with a significant decrease in stage 4 cases. This suggests that early detection through regular mammograms can lead to better health outcomes and survival rates.
A new nomogram has been developed to assess lung cancer risk in female non-smokers in China, using data from 151,834 patients. The model identified five independent risk factors, including age, chronic respiratory disease, and menopause, and showed good predictive discrimination.