Articles tagged with Cancer Screening
The study found a decreasing trend in the global TBL cancer burden from 1990 to 2019, but regional variations persisted. The burden was highest in upper-middle-income countries and lowest in high-income countries.
The study found that lung cancer screening rates among eligible adults in Maine, Michigan, New Jersey, and Rhode Island increased in 2021 compared to 2019. Consistent with prior studies, the likelihood of lung cancer screening was higher among individuals with a primary health professional
Recent studies in the New Journal of Pharmaceutical Analysis feature novel diagnostic tools, RNA sequencing-based workflows, and mechanical property evaluations to enhance cancer and cardiovascular disease treatment outcomes. These innovations aim to improve the therapeutic effect of drugs and promote personalized medicine.
Rice University engineers developed a low-cost, point-of-care DNA test for HPV infections that can be used to screen for cervical cancer. The test, which requires just two pieces of equipment and delivers results in 45 minutes, has the potential to make cervical cancer screening more accessible in low- and middle-income countries.
A recent study reveals lower lung cancer screening rates among Black veterans, underscoring the need for further research into barriers to screening and evidence-based interventions. The findings suggest that demographics alone do not fully explain these disparities.
A new study published in the Journal of the American College of Surgeons found that people who live in historically redlined areas are less likely to be screened for breast, colorectal, and cervical cancer. The legacy of redlining continues to contribute to significant disparities in cancer screening rates.
A new study found significant reductions in breast, colorectal and prostate cancers as well as melanoma diagnoses in Alberta during the COVID-19 pandemic. Diagnoses dropped by 43% for melanoma, 36% for colorectal and prostate, and 33% for breast cancer during the 'state of emergency' phase.
A study found that even insured patients with diabetes use crowdfunding platforms like GoFundMe to cover excess medical expenses, including uncovered co-pays and life-saving care. Researchers urge policymakers to consider these needs when developing affordable diabetes care policies.
A recent study published in the journal CANCER found that supplemental ultrasound screening can detect breast cancers missed by mammography, but it requires careful targeting of high-risk groups. Women with dense breasts are at higher risk of interval invasive breast cancer, and clinicians should consider other breast cancer risk facto...
Researchers have developed a polygenic risk score for colorectal cancer, which can estimate an individual's likely disease risk and identify those who may benefit from earlier screening. The score can also help determine more appropriate ages to start screening based on genetic risk.
A recent study published in Radiology found that AI algorithms performed better than the standard Breast Cancer Surveillance Consortium (BCSC) risk model for predicting five-year breast cancer risk. The AI models extracted hundreds of additional mammographic features, leading to improved predictive performance.
Researchers at UCLA have developed a new method to bioprint miniature tumor organoids that can mimic the function and architecture of real tumors. This allows for the accurate measurement of individual organoids, enabling the identification of personalized treatments for people with rare or hard-to-treat cancers.
A recent study found that American Indian and Alaska Native men are significantly less likely to receive prostate-specific antigen (PSA) testing and digital rectal exams from primary care providers compared to White men. This disparity results in poorer prostate cancer outcomes, particularly for men between 50-59 years old.
A large genome-wide association study identified novel PSA-associated variants and developed a polygenic score to correct for genetic variations in PSA levels. This approach improved biopsy referral decisions, reducing unnecessary procedures while detecting more aggressive tumors.
Researchers at UCLA Health highlight the impact of test results on lung cancer screening adherence and the potential unnecessary use of axillary ultrasound in breast cancer diagnostics. Meanwhile, a new AI system helps check endotracheal tube placement with high accuracy and user satisfaction.
A new study published in the Journal of the American College of Surgeons predicts a significant increase in cancer cases due to COVID-19 screening delays, with lung, breast, and colorectal cancers most affected. The study found that missed diagnoses during the pandemic may lead to delays in treatment and upstaging of disease.
Researchers have found a compound that can prevent cisplatin-induced renal toxicity and improve the outcomes of cancer treatment. The aromatic ketone 2',4',6'-trihydroxyacetophenone (THA) inhibits the CCBL1-mediated metabolism of cisplatin, reducing its toxic effects without affecting its potency.
A Phase 3 trial found that mailing HPV self-collection kits and scheduling assistance increased cervical cancer screenings among under-screened, underserved women. The study demonstrated the effectiveness of this approach in breaking down access barriers to screening.
Researchers found mailing HPV self-collection tests and offering assistance improved cervical cancer screening nearly two-fold among low-income women. Screening uptake increased to 72% among women who received mailed HPV kits, compared to 37% for those with scheduling assistance alone.
A US-based clinical trial found that mailing high-risk human papillomavirus (hrHPV) sampling kits to low-income, under-screened women increased cervical cancer screening uptake by nearly double. The study used intensive community outreach campaigns and mailed HPV kits with effective help scheduling in-person appointments.
A new study found that being overweight or obese during early and middle adulthood increases the risk of gastrointestinal cancers in later life. The research also suggests that frequent aspirin use does not modify this increased risk.
A new study by Brown researchers found that 33.8% of patients with low-dose computed tomography (LDCT) screening had significant incidental findings, many of which were clinically important. The study suggests that standardizing reporting of these findings could improve patient care and reduce unnecessary medical interventions.
Researchers developed a virtual framework to investigate the effectiveness of optoacoustic tomography for breast cancer screening in people with darker skin. The results confirmed that tumors can be harder to locate in individuals with darker skin, highlighting the need to optimize imaging systems to mitigate racial bias.
Researchers found that women with denser breasts who developed cancer had slower declining density over time. The study suggests using past history of density in addition to current estimates to better understand risk levels and potentially identify which breast is at risk.
Researchers found that solriamfetol, armodafinil–modafinil, and pitolisant reduce excessive daytime sleepiness in patients with obstructive sleep apnea already using conventional therapy. However, patients may be more likely to discontinue the use of these medications due to adverse events including headache, anxiety, and insomnia.
Researchers created organoids from patient tissues to test chemotherapy drugs and identified genetic signatures that predict treatment response, offering high accuracy in personalized drug screening. This breakthrough may help select effective drugs for individual patients, reducing trial and error.
The American College of Radiology (ACR) has introduced new guidelines recommending earlier and more intensive breast cancer screening for high-risk women, including Black women. According to the ACR, risk assessment by age 25 is necessary to determine if screening should start before age 40.
Researchers have found four key red flags for early-onset colorectal cancer, including abdominal pain and rectal bleeding, which can indicate an increased risk in younger adults. Early detection through timely endoscopy and follow-up is crucial to improve survival rates.
A new study suggests combining digital cancer risk assessment with point-of-care genetic testing can help overcome clinical workflow challenges that prevent at-risk patients from accessing genetic testing. The approach more than doubled the average uptake of genetic testing, showing promise for cancer prevention and detection.
A study found that people with severe mental illness have lower attendance rates at cancer screenings, particularly for bowel, breast, and cervical cancers. This disparity is widest among those living in more deprived parts of the country and from ethnic minority backgrounds.
A study published in Radiology found that AI can analyze breast mass images from low-cost portable ultrasound machines and accurately identify cancer. The technology showed great promise for improving breast health care in low-resource settings, reducing delays in diagnosis and potentially saving lives.
While smoking rates, physical inactivity, and heavy alcohol consumption declined, obesity prevalence increased, and cervical cancer screening declined between 2019 and 2021. Disparities by racial/ethnic and socioeconomic status persisted, highlighting the need for targeted interventions.
A first-of-its-kind study has estimated that transgender women taking estrogen are at a higher risk for prostate cancer, with 14 cases per 10,000 people. The study found disparities in diagnosis rates among different racial groups.
A new study found that remote outreach involving interactive education and follow-up support via telephone increased breast, cervical, and colorectal cancer screening rates among rural women. The combination of a remotely delivered interactive DVD and patient navigation services resulted in a six-fold increase in screenings.
A University of Houston team has discovered new biomarkers for early detection of bladder cancer, including D-dimer and IL-8, which may identify disease progression. The study's findings could lead to a simple urine test as the new standard for bladder cancer diagnosis.
Researchers at ETH Zurich have developed a new method called pharmacoscopy to test treatment options for multiple myeloma patients. This high-throughput screening platform analyzes the reactions of cancer cells to various treatments, offering personalized therapeutic strategies.
A study of 415,000 US female breast cancer deaths from 2011 to 2020 found that Black women should start screening earlier than previously recommended. Health policy makers and clinicians may consider an alternative approach with race- and ethnicity-adapted age recommendations for breast cancer screening.
The USPSTF finds the current evidence is insufficient to assess the balance of benefits and harms of visual skin examination by a clinician to screen for skin cancer. Skin cancer is the most commonly diagnosed cancer in the U.S., with melanomas causing the most skin cancer deaths.
Despite the decline in most services, FQHCs reported an increase in patient visits for substance use disorder, depression, anxiety, and sexually transmitted infections. Quality-of-care measures also plummeted, with only one measure returning to pre-pandemic levels.
Researchers found a 14.4% decline in new cancer diagnoses in 2020 compared to prior years, correlating with stay-at-home orders during the COVID-19 pandemic. The study estimates that around 200,000 people may have had undiagnosed or untreated cancer cases during this time.
The NCCN 2023 Annual Conference emphasized the importance of fostering welcoming environments for patients and staff, ensuring care meets latest standards, and rejecting a one-size-fits-all approach. Key findings included the need to address systemic bias, social determinants of health, and staffing issues in cancer care.
A study published in Radiology found that digital breast tomosynthesis improved breast cancer screening performance and increased radiologists' interpretive accuracy compared to digital mammography. The results showed higher detection rates, sensitivity, and specificity for DBT, with 97.6% of assessed radiologists meeting recommended p...
Researchers analyzed Hispanic adults' cancer knowledge, beliefs, and behaviors in Indiana, finding unexpected trends. The study provides guidance for targeted public health outreach and future research.
Researchers at St. Jude Children's Research Hospital developed a novel combination therapy approach that uses both BET and GSK3 inhibitors against KMT2A mutated leukemia, overcoming drug resistance without increasing toxicity. The approach was confirmed in cell lines and xenograft mouse models, and holds promise for further development.
Researchers at the University of Chicago have found that adding small molecules called immunomodulators to vaccine adjuvants can regulate the body's response to vaccines, reducing negative side effects. The study increased antibody response in flu vaccine models and reduced inflammation in typhoid vaccine models.
A recent study identified novel genes that influence PARP inhibitor response in prostate cancer, including MMS22L and RNASEH2B. The research found that loss of CHEK2, a previously approved biomarker, confers resistance to PARP inhibition, highlighting the need for comprehensive genomic analysis to improve treatment decisions.
A study found that high deductible health plans may lead women to skip additional testing after an abnormal mammogram finding, particularly those with lower incomes and education levels. This can result in delays in diagnosis and treatment, worsening breast cancer outcomes.
The COVID-19 pandemic had a substantial and diverse impact on cancer care, with changes to screening, diagnosis, and treatment reported. However, the available evidence on how this affected cancer prognosis is limited.
A new study by the University of Maryland School of Medicine found that ChatGPT provides correct information on breast cancer screening for most questions. However, inconsistencies and outdated information were detected in some responses. The researchers recommend relying on doctors for advice due to the limitations of ChatGPT.
Research outlines actionable steps to address longstanding health disparities in breast cancer screening and treatment options. Surgeons can drive change by maintaining awareness of existing disparities and providing additional resources to patients.
A proactive patient education/recruitment program, administered with a nurse navigator, identified 37.3% more eligible patients for low-dose computed tomography (LDCT) screenings for lung cancer. The program led to a 42% increase in LDCT prescriptions among willing and eligible patients.
Researchers investigated perspectives of Black patients on shared decision making (SDM) during medical appointments. They identified preferences for humanistic communication, the need for doctors to account for family members' roles in decision-making, and a growing mistrust in doctors. The study's findings offer insights for adapting ...
Researchers have found that valosin-containing protein (VCP) is essential for KRAS-mutant pancreatic ductal adenocarcinoma cell growth and survival. Inhibiting VCP, combined with autophagy inhibition, enhances efficacy in preclinical studies.
Researchers developed an AI-based diagnostic screening system called DeepGlioma to analyze tumor specimens and detect genetic mutations rapidly. The system identified molecular subgroups with high accuracy and has the potential to improve access and speed of diagnosis for patients with deadly brain tumors.
A study published in The Lancet Public Health found that women with mental illness are twice as likely to develop cervical cancer due to low screening rates and increased incidence of precancerous lesions. Researchers highlight the need for proactive measures to address inequality in care.
A new study from PetDx shows OncoK9 performs similarly to its landmark clinical validation study in real-world settings, detecting 26 types of cancer in high-risk dogs. The test also provides peace of mind for veterinarians and families by detecting cancer in over 94% of negative cases.
A study of 19,000 female participants found mailing HPV self-sampling kits to be an efficient way to increase screening rates among eligible women. This cost-effective approach supports the use of mailed HPV kits as an outreach strategy for U.S. healthcare systems.
Researchers from Dana-Farber Cancer Institute have outlined a path toward understanding, preventing, and treating young-onset colorectal cancer. The study highlights the need for multidisciplinary research involving diverse populations to account for the complexity of the disease.
A national US study found trust in government cancer information plummeted by 53% among non-Hispanic Black people during the pandemic. Meanwhile, trust in doctors remained high, highlighting the need for effective communication and access to healthcare services.
A study of US newspaper articles found that lung cancer screening was generally positively covered between 2010 and 2022. However, crucial aspects such as enrollment criteria and cost issues were frequently omitted, highlighting a need for radiologists to take an active role in media coverage.