Articles tagged with Cancer Screening
A new study by Brown researchers found that 33.8% of patients with low-dose computed tomography (LDCT) screening had significant incidental findings, many of which were clinically important. The study suggests that standardizing reporting of these findings could improve patient care and reduce unnecessary medical interventions.
Researchers developed a virtual framework to investigate the effectiveness of optoacoustic tomography for breast cancer screening in people with darker skin. The results confirmed that tumors can be harder to locate in individuals with darker skin, highlighting the need to optimize imaging systems to mitigate racial bias.
Researchers found that solriamfetol, armodafinil–modafinil, and pitolisant reduce excessive daytime sleepiness in patients with obstructive sleep apnea already using conventional therapy. However, patients may be more likely to discontinue the use of these medications due to adverse events including headache, anxiety, and insomnia.
Researchers created organoids from patient tissues to test chemotherapy drugs and identified genetic signatures that predict treatment response, offering high accuracy in personalized drug screening. This breakthrough may help select effective drugs for individual patients, reducing trial and error.
The American College of Radiology (ACR) has introduced new guidelines recommending earlier and more intensive breast cancer screening for high-risk women, including Black women. According to the ACR, risk assessment by age 25 is necessary to determine if screening should start before age 40.
Researchers have found four key red flags for early-onset colorectal cancer, including abdominal pain and rectal bleeding, which can indicate an increased risk in younger adults. Early detection through timely endoscopy and follow-up is crucial to improve survival rates.
A new study suggests combining digital cancer risk assessment with point-of-care genetic testing can help overcome clinical workflow challenges that prevent at-risk patients from accessing genetic testing. The approach more than doubled the average uptake of genetic testing, showing promise for cancer prevention and detection.
A study found that people with severe mental illness have lower attendance rates at cancer screenings, particularly for bowel, breast, and cervical cancers. This disparity is widest among those living in more deprived parts of the country and from ethnic minority backgrounds.
A study published in Radiology found that AI can analyze breast mass images from low-cost portable ultrasound machines and accurately identify cancer. The technology showed great promise for improving breast health care in low-resource settings, reducing delays in diagnosis and potentially saving lives.
While smoking rates, physical inactivity, and heavy alcohol consumption declined, obesity prevalence increased, and cervical cancer screening declined between 2019 and 2021. Disparities by racial/ethnic and socioeconomic status persisted, highlighting the need for targeted interventions.
A first-of-its-kind study has estimated that transgender women taking estrogen are at a higher risk for prostate cancer, with 14 cases per 10,000 people. The study found disparities in diagnosis rates among different racial groups.
A new study found that remote outreach involving interactive education and follow-up support via telephone increased breast, cervical, and colorectal cancer screening rates among rural women. The combination of a remotely delivered interactive DVD and patient navigation services resulted in a six-fold increase in screenings.
A University of Houston team has discovered new biomarkers for early detection of bladder cancer, including D-dimer and IL-8, which may identify disease progression. The study's findings could lead to a simple urine test as the new standard for bladder cancer diagnosis.
Researchers at ETH Zurich have developed a new method called pharmacoscopy to test treatment options for multiple myeloma patients. This high-throughput screening platform analyzes the reactions of cancer cells to various treatments, offering personalized therapeutic strategies.
A study of 415,000 US female breast cancer deaths from 2011 to 2020 found that Black women should start screening earlier than previously recommended. Health policy makers and clinicians may consider an alternative approach with race- and ethnicity-adapted age recommendations for breast cancer screening.
The USPSTF finds the current evidence is insufficient to assess the balance of benefits and harms of visual skin examination by a clinician to screen for skin cancer. Skin cancer is the most commonly diagnosed cancer in the U.S., with melanomas causing the most skin cancer deaths.
Despite the decline in most services, FQHCs reported an increase in patient visits for substance use disorder, depression, anxiety, and sexually transmitted infections. Quality-of-care measures also plummeted, with only one measure returning to pre-pandemic levels.
Researchers found a 14.4% decline in new cancer diagnoses in 2020 compared to prior years, correlating with stay-at-home orders during the COVID-19 pandemic. The study estimates that around 200,000 people may have had undiagnosed or untreated cancer cases during this time.
The NCCN 2023 Annual Conference emphasized the importance of fostering welcoming environments for patients and staff, ensuring care meets latest standards, and rejecting a one-size-fits-all approach. Key findings included the need to address systemic bias, social determinants of health, and staffing issues in cancer care.
A study published in Radiology found that digital breast tomosynthesis improved breast cancer screening performance and increased radiologists' interpretive accuracy compared to digital mammography. The results showed higher detection rates, sensitivity, and specificity for DBT, with 97.6% of assessed radiologists meeting recommended p...
Researchers analyzed Hispanic adults' cancer knowledge, beliefs, and behaviors in Indiana, finding unexpected trends. The study provides guidance for targeted public health outreach and future research.
Researchers at St. Jude Children's Research Hospital developed a novel combination therapy approach that uses both BET and GSK3 inhibitors against KMT2A mutated leukemia, overcoming drug resistance without increasing toxicity. The approach was confirmed in cell lines and xenograft mouse models, and holds promise for further development.
Researchers at the University of Chicago have found that adding small molecules called immunomodulators to vaccine adjuvants can regulate the body's response to vaccines, reducing negative side effects. The study increased antibody response in flu vaccine models and reduced inflammation in typhoid vaccine models.
A new study by the University of Maryland School of Medicine found that ChatGPT provides correct information on breast cancer screening for most questions. However, inconsistencies and outdated information were detected in some responses. The researchers recommend relying on doctors for advice due to the limitations of ChatGPT.
A recent study identified novel genes that influence PARP inhibitor response in prostate cancer, including MMS22L and RNASEH2B. The research found that loss of CHEK2, a previously approved biomarker, confers resistance to PARP inhibition, highlighting the need for comprehensive genomic analysis to improve treatment decisions.
A study found that high deductible health plans may lead women to skip additional testing after an abnormal mammogram finding, particularly those with lower incomes and education levels. This can result in delays in diagnosis and treatment, worsening breast cancer outcomes.
The COVID-19 pandemic had a substantial and diverse impact on cancer care, with changes to screening, diagnosis, and treatment reported. However, the available evidence on how this affected cancer prognosis is limited.
Researchers investigated perspectives of Black patients on shared decision making (SDM) during medical appointments. They identified preferences for humanistic communication, the need for doctors to account for family members' roles in decision-making, and a growing mistrust in doctors. The study's findings offer insights for adapting ...
Research outlines actionable steps to address longstanding health disparities in breast cancer screening and treatment options. Surgeons can drive change by maintaining awareness of existing disparities and providing additional resources to patients.
A proactive patient education/recruitment program, administered with a nurse navigator, identified 37.3% more eligible patients for low-dose computed tomography (LDCT) screenings for lung cancer. The program led to a 42% increase in LDCT prescriptions among willing and eligible patients.
Researchers have found that valosin-containing protein (VCP) is essential for KRAS-mutant pancreatic ductal adenocarcinoma cell growth and survival. Inhibiting VCP, combined with autophagy inhibition, enhances efficacy in preclinical studies.
A study published in The Lancet Public Health found that women with mental illness are twice as likely to develop cervical cancer due to low screening rates and increased incidence of precancerous lesions. Researchers highlight the need for proactive measures to address inequality in care.
Researchers developed an AI-based diagnostic screening system called DeepGlioma to analyze tumor specimens and detect genetic mutations rapidly. The system identified molecular subgroups with high accuracy and has the potential to improve access and speed of diagnosis for patients with deadly brain tumors.
A new study from PetDx shows OncoK9 performs similarly to its landmark clinical validation study in real-world settings, detecting 26 types of cancer in high-risk dogs. The test also provides peace of mind for veterinarians and families by detecting cancer in over 94% of negative cases.
A study of 19,000 female participants found mailing HPV self-sampling kits to be an efficient way to increase screening rates among eligible women. This cost-effective approach supports the use of mailed HPV kits as an outreach strategy for U.S. healthcare systems.
Researchers from Dana-Farber Cancer Institute have outlined a path toward understanding, preventing, and treating young-onset colorectal cancer. The study highlights the need for multidisciplinary research involving diverse populations to account for the complexity of the disease.
A national US study found trust in government cancer information plummeted by 53% among non-Hispanic Black people during the pandemic. Meanwhile, trust in doctors remained high, highlighting the need for effective communication and access to healthcare services.
A study of US newspaper articles found that lung cancer screening was generally positively covered between 2010 and 2022. However, crucial aspects such as enrollment criteria and cost issues were frequently omitted, highlighting a need for radiologists to take an active role in media coverage.
A large study of over 1 million women found DBT had a higher breast cancer detection rate and lower false positive rates compared to 2D digital mammography. The results suggest that DBT may be the more effective screening method for early breast cancer detection.
A systematic review of 33 randomized controlled trials found that yoga improved gait speed and lower extremity strength in inactive older people. However, it did not offer a benefit for frailty markers compared to exercise or tai chi.
Axillary lymphadenopathy after a COVID-19 vaccine booster dose resolves at a mean of 102 days. Findings support follow-up intervals of at least 12 weeks to avoid delaying screening mammography for suspected vaccine-related lymphadenopathy.
A new study suggests that digital rectal examination (DRE) is not a reliable screening tool for early prostate cancer detection. Researchers found that DRE missed many cancers in their early stages, with only 3 out of 57 suspicious cases detected. This method was compared to PSA testing, which detected four times more prostate cancers.
A recent study has identified nine new genetic variants that increase the risk of prostate cancer in men of African descent, including a variant linked to aggressive forms. The findings can be used to refine polygenic risk scores and identify high-risk patients for earlier screenings.
A Tulane University study found that areas with paid sick leave mandates experienced significant increases in breast cancer (4%) and colorectal cancer (6-8%) screenings among private sector employees. The findings suggest that non-monetary barriers to healthcare access can have a meaningful impact on health outcomes.
A new study found that women with BRCA1 or BRCA2 mutations have a cumulative risk of 49% developing any type of cancer after age 50. Risk-reducing surgeries like mastectomies and BSOs can lower this risk, but many women opt out despite elevated risk. Genetic testing is crucial for accurate risk assessment and personalized care.
Researchers have identified three novel pathogenic variants of the ATR gene as predisposing to male breast cancer. These variants were found in a cohort of individuals with early onset and familial breast cancers, using a combination of exome sequencing and functional investigations. The study suggests that extended genetic analysis ca...
Researchers found that a combination of symptom and high-level viral rebound after untreated COVID-19 infection is rare, occurring in only 3 percent of study participants. This suggests that accounting for underlying rates of symptom relapse is crucial when evaluating antiviral treatment effects.
Researchers examined three epigenetic age acceleration measurements and found inverse associations with lung cancer risk in men and younger participants. However, these findings did not support a positive association between epigenetic age measures and lung cancer risk in the study.
The ESMO Gynaecological Cancers Congress 2023 will present the latest treatments and insights for ovarian, uterine, cervical, and rare gynaecological cancers. Around 80 studies will be presented on strategies to overcome PARP inhibitors mechanisms of resistance in ovarian cancer.
Researchers at the University of East Anglia have developed a new blood test to detect prostate cancer with 94% accuracy. The Prostate Screening EpiSwitch (PSE) blood test significantly enhances overall detection accuracy for at-risk men, offering a rapid and minimally invasive diagnosis.
A new study highlights the dramatic impact of the COVID-19 pandemic on cancer-screening delays, with significant delays observed among younger individuals and diverse populations. The study found that 11%-36% of planned cancer screenings were postponed due to COVID-19, with the greatest delays seen for Pap tests and colonoscopies.
Researchers found that AI significantly improved the detection of lung nodules on chest X-rays, detecting actionable nodules at a rate of 0.59% compared to 0.25% without AI assistance. The study suggests that AI may work consistently across different populations.
A systematic review found that higher vitamin D intake was associated with a 15% decreased likelihood of developing type 2 diabetes in adults with prediabetes. Inexpensive vitamin D supplementation could delay the development of diabetes in over 10 million people worldwide.
A study published in CANCER found that people's defensive beliefs can prevent them from taking at-home stool tests for colorectal cancer screening. Individuals who reacted defensively were more likely to believe that a healthy lifestyle or regular bowel movements mean they don't need to be screened.
Cancer screening rates for breast and lung cancers persisted despite initial pandemic surges, highlighting the need for targeted interventions. The study found that successful strategies to improve screening rates must address pandemic-related barriers.
Awareness of breast density increases perceived risk and uncertainties about screening choices in Spanish-speaking women. However, these effects are short-term and do not persist over time, suggesting that educational outreach may help clarify implications for personal risk and screening decisions.
A new study analyzed 3,452 dogs with cancer to determine median ages of diagnosis based on characteristics such as weight, breed, and sex. The findings suggest that giant breeds, males, and purebred dogs tend to receive a cancer diagnosis at relatively younger ages.
Patients living in Southern states with expanded Medicaid were more likely to receive early treatment for invasive breast cancer. Despite this, the proportion of patients undergoing treatments actually decreased across all states.
A meta-analysis of 22 studies found that breast MRI was superior to other supplemental screening methods in detecting breast cancer in women with dense breasts. This is because breast MRI can detect even the smallest of cancers, making it a valuable tool for identifying high-risk patients.
The institutions will develop trials to screen cervical cancer patients in low-resource countries, aiming to prevent advanced cancer. The collaboration aims to achieve the World Health Organization's goal of eliminating cervical cancer by adapting and innovating prevention strategies.