Articles tagged with Cancer Screening
A study published in Radiology found that digital breast tomosynthesis (DBT) improved cancer detection and reduced false negative rates compared to digital mammography. DBT also showed advantages in imaging women with dense breasts, leading to lower recall rates and more effective cancer screening.
Residents of Southwest Virginia have set priorities for cancer prevention and early detection, focusing on tobacco cessation, HPV vaccination, lung and colorectal cancer screenings. The region's partnership with the UVA Cancer Center Without Walls aims to improve health outcomes through a collaborative effort.
A study published in Radiology found that digital breast tomosynthesis (DBT) with synthetic mammography improved cancer detection rates compared to traditional digital mammography. The technique reduced radiation exposure and detected a higher proportion of early-stage cancers, particularly among women with dense breasts.
A meta-analysis of eight randomized clinical trials found that low-dose CT screening reduces lung cancer-caused death by 0.4%, translating to one preventable death per 250 at-risk adults. The study suggests the benefits may outweigh potential harms from overdiagnosis, aligning with US Preventive Services Task Force recommendations.
A new study from the American Cancer Society found that active older adults have better overall physical and mental health. Higher amounts of regular moderate- to vigorous-intensity physical activity and lower duration of sedentary time are associated with higher global mental and physical health.
Research at the European Breast Cancer Conference highlights a significant difference in survival rates between breast cancers detected during screening and those detected in the interval between screenings. Screen-detected cancers have higher eight-year distant metastasis-free interval rates, even among high-risk tumours.
A study by Spanish researchers found that women with incident, proliferative benign breast disease are at a nearly four-fold increased risk of developing breast cancer compared to those with no BBD. The study analyzed data from over 629,000 women and recommends personalized screening strategies based on individual risk factors.
A repeated testing protocol for COVID-19 among patients with cancer was examined in a quality improvement study. The study found that asymptomatic cancer patients can be safely screened for COVID-19 without increasing the risk of infection.
Drs. Dennis Lo, Karen Mann and Ronald Przygodzki are recognized for their pioneering work in non-invasive prenatal testing and cancer detection using circulating nucleic acids. Their innovations have created a paradigm in prenatal medicine and advanced the field of molecular diagnostics.
A program using mail-in stool samples is shown to be an effective and cost-effective alternative to in-person colonoscopies for detecting colon cancer. The study identified nine best practices for implementing such programs, including patient navigation and high-quality testing kits.
Research finds strong association between smoking and reduced cancer screening services use among postmenopausal women, leading to advanced disease diagnosis. Current smokers are nearly 3 times as likely to be diagnosed with late stage breast cancer, and over twice as likely to be diagnosed with late stage bowel cancer.
A new study reveals that non-white Americans, especially Asian Americans, are at a higher risk of gastric cancer compared to non-Hispanic whites. The risk is highest among Korean Americans age 50 and older, who have a 12-fold to 14.5-fold higher risk of developing stomach cancer.
Researchers found that 59.3% of men and 56.2% of women over 75 received unnecessary colorectal cancer screenings, while 45.8% of women under 65 received unnecessary cervical cancer screenings. The study highlights the need for targeted screening recommendations to balance risks with benefits.
Research from the Sidney Kimmel Cancer Center found significant decreases nationwide in cancer-related care, including a -56.9% decline in any neoplasm encounters and a 74% drop in new incidence neoplasms. Mammograms declined by 89.2% and colorectal cancer screenings fell by 84.5% during the pandemic.
Starting at age 25 prevented marginally more deaths, but with more testing and emotional stress. All annual screening approaches save lives, with a combined approach of both breast MRI and mammography beginning at age 25 preventing the most deaths.
A study published in CANCER found that Medicaid expansion significantly reduced the likelihood of being diagnosed with deadly metastatic cancer among Americans with low income. The research analyzed data from 12,760 individuals and showed a 15% lower odds of having metastatic cancer after Medicaid expansion.
A systematic review and meta-analysis found that digital mammography did not improve health outcomes for women screened with the technology. The study analyzed 24 studies and found a small increase in cancer detection rates, but this was largely due to more detection of non-invasive DCIS and no significant difference in invasive cancer...
Key recommendations from the Philadelphia Prostate Cancer Consensus Conference include performing genetic testing for all men with metastatic prostate cancer and those with a family history of hereditary cancers. Recommended genes for testing include BRCA2, BRCA1, and DNA mismatch repair genes. Genetic testing is also recommended to in...
A new study by the American Cancer Society finds that racial disparities in cancer mortality result in significant economic losses, with $3.2 billion in lost earnings avoided in 2015 if non-Hispanic black cancer deaths and earning rates had been equal to those of non-Hispanic white cancer patients. The study highlights the importance o...
A new study found that personalized ovarian cancer risk prediction reduces cancer worry and anxiety in women. Participants who received the personalized risk estimate were more likely to take preventative action and reduce their risk of developing ovarian cancer.
A new saliva test has detected early throat cancer in a person with no symptoms, highlighting a potential breakthrough in cancer screening. The test identified HPV-DNA in the saliva of an infected individual, allowing for early removal of the affected tonsil through surgery.
A multicancer blood test safely detected 26 undiagnosed cancers and enabled potentially curative treatment in a study of over 9,900 women. The test was found to be complementary and additive to standard screening methods for detecting breast, colon, and lung tumors.
Researchers developed a multi-cancer blood test that detected some cancers, including ovarian cancers, and successfully screened for non-cancer causes before diagnostic tests. The test showed promise as a minimally invasive option to increase cancer detection rates in populations already following standard screening approaches.
A blood test developed by Thrive Earlier Detection Corp. has identified multiple cancers in over 10,000 women without a prior history of cancer. The study found that the test more than doubled the number of 'screen-detected' cancers, increasing from 25% to 52%.
A team of researchers used genome-wide CRISPR technology to identify RNA-binding proteins, including Staufen2, that sustain and protect drug-resistant leukemia stem cells. Loss of Staufen2 led to a reduction in leukemia growth and improved survival in mouse models.
A study found that using family history-based guidelines to identify individuals for early screening could help detect young-onset colorectal cancer. Researchers analyzed data from adults with and without colorectal cancer and estimated the potential impact of these guidelines on early detection and prevention.
The blood test uses methylation patterns to detect cancer and identify its origin, achieving a 93% accuracy rate. It can detect over 50 cancer types, including the most deadly ones, with a low false positive rate of 0.7%, often before symptoms show up.
A large observational study compared radiologists' recall rates and cancer detection in breast cancer screenings using digital breast tomosynthesis (DBT) and digital mammography. The study found that DBT had higher cancer detection rates but lower recall rates than digital mammography.
Researchers found that personalized cancer outreach using machine learning and targeted interventions can improve return on investment by 74-96%. The study used a randomized field experiment to analyze the effectiveness of different outreach programs, which varied in their impact depending on patient demographics and characteristics.
Researchers identified 15 potent tumor suppressor genes that, when mutated, triggered rapid growth of HNSCC in mice. These genes include ADAM10 and AJUBA, which are also mutated in human HNSCC. The study reveals the identity of rare driver mutations in tumor-suppressing genes using a mouse-based CRISPR screen.
A collaborative research team from Dartmouth and Honduras found a high level of participation in rural cancer screening events, resulting in over 88% of identified individuals seeking follow-up care. The 'multiphasic' approach involved multiple cancer screenings in one event, which was well-received by local communities.
A new study published in Radiology found that digital breast tomosynthesis (DBT) improved cancer detection rates and reduced false positives compared to digital mammography (DM). DBT screening detected a higher proportion of poor prognosis cancers than DM, with better visualization of lesions and reduced tissue superimposition.
A new study suggests that lengthening the time between prostate cancer screenings can significantly reduce overdiagnosis and improve outcomes. The research found that discontinuing screening at age 60 would greatly reduce overdiagnoses by 79-82%, but save fewer lives compared to screening until age 69.
Researchers found no association between opioid use and cancer screening, despite higher healthcare utilization among opioid users. Key cancer screenings were more common in women with frequent doctor visits regardless of opioid status.
Cancer survivors diagnosed between ages 15-20 have an increased risk of premature death and severe health conditions compared to siblings. The study highlights the need for long-term screening of young cancer survivors throughout their lives.
A study published in BMJ Sexual & Reproductive Health found that having 10 or more lifetime sexual partners is associated with a heightened risk of cancer diagnosis in both men and women. Women who reported this number were 91% more likely to be diagnosed, while those with limiting chronic conditions were 64% more likely. The study sug...
A new study from UNM Comprehensive Cancer Center scientists reveals that cervical cancer screening every three years is protective against cervical cancer. Most cancers are caught before spreading, making treatment easier. Screening was found to reduce localized and distant cancers.
Researchers found a significant spike in new colorectal cancer diagnoses between ages 49 and 50, indicating many latent cases were likely going undiagnosed until screening began. The majority of these cases (93%) were invasive, requiring aggressive treatment, including surgery.
The study highlights the efficacy of Bluestar Genomics' 5-hmC signal detection technology for detecting breast, lung, pancreatic, and prostate cancer from a single blood draw. The technology demonstrated high performance in classifying samples with high Area Under the Curve measures.
Bowel cancer screening tests can miss patients due to NHS staff shortages, particularly in England where lower haemoglobin levels warrant further investigation. Cancer Research UK calls for significant investment to train and recruit more staff to diagnose patients earlier.
A new study finds that Australians are increasingly being diagnosed with harmless cancers, exposing them to unnecessary surgeries and chemotherapy. Overdiagnosis rates have increased significantly since 1982, with 24% of prostate cancers, 73% of thyroid cancers, and 58% of melanomas overdiagnosed in men.
Researchers at OHSU assess barriers to care in 10 preventive services, finding enhanced services like patient navigation increase cancer screening rates. Additional research is needed to better understand patient and provider barriers and the role of health information technology.
Thyroid cancer rates in the US have stabilized since 2014, with a decline in new cases per 100,000 people from 14.7 to 14.1 between 2009 and 2016. The rise in thyroid cancer was largely due to increased screening and imaging over the past three decades.
The study validated the reproducibility of CRISPR-Cas9 functional genetic screens, creating the largest genetic screen resource for cancer research. This combined dataset will help narrow down the list of targets for the next generation of cancer treatments, speeding up the discovery and development of new drugs.
Recent colorectal cancer screening rates more than doubled among people ages 45 to 49, a trend unique to this age group. The increase in screening was attributed to the release of updated American Cancer Society guidelines recommending screening in that age range.
The Cancer Prevention and Control Research Network has published a supplemental issue of Preventive Medicine highlighting disparities in cancer prevention and control. The research findings report on factors contributing to rural disparities and strategies to improve equity in cancer screening rates.
A new book published by international cancer experts offers promising research findings on Latino cancer and strategies for reducing health disparities. The book provides recommendations for creating studies based on subgroups and moving towards precision medicine to address the projected 142% rise in Latino cancer cases by 2030.
A new study found that biennial mammography screening resulted in smaller and less advanced breast cancer tumors compared to annual screenings. The study also discovered that women receiving biennial screenings tended to have more aggressive treatment options, such as chemotherapy and axillary lymph node dissection.
A study on cancer trends in Canada from 1971 to 2015 found an increase in breast and colorectal cancers among younger adults, particularly women aged 30-39. In contrast, cancer incidence has decreased in older age groups, with declines seen in cervical, lung, bladder, and prostate cancers across most age categories.
Scientists at UCLA Jonsson Comprehensive Cancer Center developed a new high-throughput screening system that identifies selective inhibitors of metabolic pathways. The approach revealed multiple kinase inhibitors block nucleotide metabolism and its targets.
A new study from the University of Pennsylvania School of Medicine found that implementing an electronic health record nudge increased cancer screening orders by 22% and 14%, respectively. However, the study also showed that patients' follow-through on screenings remained largely unchanged. The researchers suggest that future intervent...
A study published in The BMJ found substantial variation in bowel cancer rates after colonoscopies in England, with lower rates seen at NHS providers. Reducing this variation could prevent or diagnose more cancers earlier, the researchers suggest.
Researchers found a 75% reduction in gastric cancer risk after eliminating Helicobacter pylori infection. Higher rates of gastric cancer were observed among African American, Asian, and Hispanic populations, as well as men who smoke.
Research found that colonoscopy accuracy has improved overall in England, but variation between providers remains. The study suggests that some independent providers have higher rates of missed cancers compared to NHS providers.
A study found that cervical cancer screening rates decline among women aged 45-65, particularly those with lower education, rural residency, or lack of insurance. The study highlights the need for increased awareness and access to screenings for vulnerable populations.
Researchers aim to increase colorectal cancer screening and follow-up care among underserved individuals in Appalachia through a multi-institutional $5.7 million grant. The goal is to improve guideline-recommended screenings and healthcare services, particularly in rural communities where trust is a barrier.
New research found that women with diabetes are up to a quarter less likely to undergo recommended cancer screenings, including cervical, breast, and colorectal cancer tests. The study suggests that the burden of diabetes care management in primary care may contribute to lower uptake of cancer screening.
A recent study comparing digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) found that DBT significantly increased cancer detection rates for invasive, minimal, estrogen receptor-positive invasive, and node-negative cancers. However, the difference was not significant for ductal carcinoma in situ.
A new study presented at the IASLC 2019 North America Conference on Lung Cancer found that lung cancer screening guidelines are inadequate to diagnose patients who contract lung cancer from occupational exposure, including first responders. Low-dose computed tomography was shown to detect disease earlier in this population.
Experts advise against routine bowel cancer testing for everyone aged 50-79 due to small benefits and potential harms. However, men and women with a risk of 3% or more in the next 15 years should consider screening.