Articles tagged with Cancer Screening
A recent study found that only 19% of women in sub-Saharan Africa underwent cervical cancer screenings between 2011 and 2018. The rates varied greatly by country, with some countries having nearly 46% of women screened versus less than 1%. Increasing screenings is crucial to detect the disease early and improve treatment outcomes.
The USPSTF now recommends starting colorectal cancer screening at age 45 for most adults, with selective offers for those aged 76-85. Nearly one-third of eligible adults were not up to date with screening in 2018.
A new study found a link between drinking sugar-sweetened beverages and an increased risk of developing colorectal cancer in women under age 50. Heavy consumption during adolescence and young adulthood can increase disease risk, suggesting public health efforts to reduce sugar intake may be beneficial.
The COVID-19 pandemic led to a significant decline in cancer screenings for breast, colorectal, and prostate cancers. According to the study, screening rates dropped by an estimated 22% during the pandemic.
Geisinger Health System has been awarded a $3.6 million contract from the National Cancer Institute to analyze genetic data from its MyCode Community Health Initiative. The study aims to identify specific gene variants linked to cancer risk, expanding the list of genes used for genetic cancer screening.
The NCCN Foundation has awarded $150,000 in funding to six young investigators advancing research on cancer prevention, racial disparities in screening, and CAR T-cell therapy. The recipients will present their research at the NCCN 2023 Annual Conference.
A recent study published in Radiology found that 3D-mammography reduces the number of breast cancer cases diagnosed between routine screenings. The study included almost 15,000 women who received both 3D-mammography and traditional mammography, and compared cancers detected in between screenings.
A study published in Radiology found that digital breast tomosynthesis (DBT) reduces the rate of interval cancers, which are more aggressive than screen-detected cancers. The study suggests that DBT may contribute to lower breast cancer mortality by detecting rapidly growing cancers with poorer prognosis.
A new technique called GETMap can trace the source of circulating DNA in the blood, which could be used to monitor organ transplant rejection, detect hidden cancers, and even screen for early asymptomatic cancers. The test identifies genetic and epigenetic markers to determine whether DNA comes from a specific tissue or organ.
Screenings for breast cancer and colon cancer dropped dramatically during the pandemic but returned to near-normal levels by July 2020. Researchers analyzed insurance claims from over 6 million Americans and found that mammography rates among women aged 45-64 declined by 96% in March and April 2020.
Researchers found that people searching for objects in 3D image stacks are less successful than those searching for the same in single 2D images. This is due to a bottleneck in human vision and cognition, where humans under-explore 3D search areas and rely on peripheral visual processing.
A new UCF study found that Chinese adults seldom ask about cancer screenings despite family history or caregiver roles. Age was a factor, with older participants being reluctant to discuss screenings due to traditional culture.
A recent study reveals an increase in cancer incidence and mortality rates in China, with rising rates seen in colorectal, pancreatic, and breast cancers. The study highlights the importance of implementing cost-effective approaches for primary prevention and collaborative efforts to reduce the cancer burden.
The study demonstrates MEK inhibitors as a promising targeted therapy for basal subtype bladder cancer, highlighting the importance of 3D cell culture drug screening. Established genomic and transcriptomic data are correlated with drug response to identify novel groups of tumors vulnerable to specific drugs.
Researchers analyzed 751 pediatric patients treated for solid tumors and found germline genomic sequencing details for inherited gene mutations. This information can help guide treatment, family screening, and prevent future cancers.
A new technique using deep mutational scanning has identified important mutations in the MSH2 gene associated with Lynch Syndrome, a major cause of hereditary non-polyposis colorectal cancer. This approach could improve predictive value of genetic screening for individuals at risk of developing colorectal cancer.
Research highlights barriers to lung cancer care for marginalized communities, including racial and ethnic minorities, LGBTQ+ individuals, and low-income patients. Key findings also show sex disparities in lung cancer incidence rates across countries.
The COVID-19 pandemic significantly affected cancer screening test utilization and subsequent cancer diagnoses in the largest US healthcare system. Researchers analyzed data to understand the impact of the pandemic on cancer care.
During the first COVID-19 surge, cancer screenings and diagnoses declined by 70% due to reduced testing. However, screening levels largely recovered in the months following the peak period. The study urges patients who delayed screenings to contact their provider to discuss rescheduling.
Radiologists question the status quo to spark positive dialog and improve patient care. Featured articles debate the use of physician extenders and incorporation of AI algorithms into daily practice.
A recent study by University of Cincinnati Cancer Center researchers shows that the pandemic had a negative impact on both preventive screening and patient outcomes for lung cancer. The team found that total monthly CT scans and new patient scans significantly decreased during the COVID-19 period, leading to increased proportion of sus...
The Stand Up To Cancer initiative will fund a 'Dream Team' of researchers and public awareness campaigns to increase screenings in medically underserved communities. The goal is to develop better approaches to colorectal cancer interception and make the disease preventable with simple tests, while addressing health disparities.
A study published in Radiology found that digital breast tomosynthesis (DBT) improved cancer detection and reduced false negative rates compared to digital mammography. DBT also showed advantages in imaging women with dense breasts, leading to lower recall rates and more effective cancer screening.
Residents of Southwest Virginia have set priorities for cancer prevention and early detection, focusing on tobacco cessation, HPV vaccination, lung and colorectal cancer screenings. The region's partnership with the UVA Cancer Center Without Walls aims to improve health outcomes through a collaborative effort.
A meta-analysis of eight randomized clinical trials found that low-dose CT screening reduces lung cancer-caused death by 0.4%, translating to one preventable death per 250 at-risk adults. The study suggests the benefits may outweigh potential harms from overdiagnosis, aligning with US Preventive Services Task Force recommendations.
A study published in Radiology found that digital breast tomosynthesis (DBT) with synthetic mammography improved cancer detection rates compared to traditional digital mammography. The technique reduced radiation exposure and detected a higher proportion of early-stage cancers, particularly among women with dense breasts.
A new study from the American Cancer Society found that active older adults have better overall physical and mental health. Higher amounts of regular moderate- to vigorous-intensity physical activity and lower duration of sedentary time are associated with higher global mental and physical health.
Research at the European Breast Cancer Conference highlights a significant difference in survival rates between breast cancers detected during screening and those detected in the interval between screenings. Screen-detected cancers have higher eight-year distant metastasis-free interval rates, even among high-risk tumours.
A study by Spanish researchers found that women with incident, proliferative benign breast disease are at a nearly four-fold increased risk of developing breast cancer compared to those with no BBD. The study analyzed data from over 629,000 women and recommends personalized screening strategies based on individual risk factors.
A repeated testing protocol for COVID-19 among patients with cancer was examined in a quality improvement study. The study found that asymptomatic cancer patients can be safely screened for COVID-19 without increasing the risk of infection.
Drs. Dennis Lo, Karen Mann and Ronald Przygodzki are recognized for their pioneering work in non-invasive prenatal testing and cancer detection using circulating nucleic acids. Their innovations have created a paradigm in prenatal medicine and advanced the field of molecular diagnostics.
A program using mail-in stool samples is shown to be an effective and cost-effective alternative to in-person colonoscopies for detecting colon cancer. The study identified nine best practices for implementing such programs, including patient navigation and high-quality testing kits.
Research finds strong association between smoking and reduced cancer screening services use among postmenopausal women, leading to advanced disease diagnosis. Current smokers are nearly 3 times as likely to be diagnosed with late stage breast cancer, and over twice as likely to be diagnosed with late stage bowel cancer.
A new study reveals that non-white Americans, especially Asian Americans, are at a higher risk of gastric cancer compared to non-Hispanic whites. The risk is highest among Korean Americans age 50 and older, who have a 12-fold to 14.5-fold higher risk of developing stomach cancer.
Researchers found that 59.3% of men and 56.2% of women over 75 received unnecessary colorectal cancer screenings, while 45.8% of women under 65 received unnecessary cervical cancer screenings. The study highlights the need for targeted screening recommendations to balance risks with benefits.
Research from the Sidney Kimmel Cancer Center found significant decreases nationwide in cancer-related care, including a -56.9% decline in any neoplasm encounters and a 74% drop in new incidence neoplasms. Mammograms declined by 89.2% and colorectal cancer screenings fell by 84.5% during the pandemic.
Starting at age 25 prevented marginally more deaths, but with more testing and emotional stress. All annual screening approaches save lives, with a combined approach of both breast MRI and mammography beginning at age 25 preventing the most deaths.
A study published in CANCER found that Medicaid expansion significantly reduced the likelihood of being diagnosed with deadly metastatic cancer among Americans with low income. The research analyzed data from 12,760 individuals and showed a 15% lower odds of having metastatic cancer after Medicaid expansion.
A systematic review and meta-analysis found that digital mammography did not improve health outcomes for women screened with the technology. The study analyzed 24 studies and found a small increase in cancer detection rates, but this was largely due to more detection of non-invasive DCIS and no significant difference in invasive cancer...
Key recommendations from the Philadelphia Prostate Cancer Consensus Conference include performing genetic testing for all men with metastatic prostate cancer and those with a family history of hereditary cancers. Recommended genes for testing include BRCA2, BRCA1, and DNA mismatch repair genes. Genetic testing is also recommended to in...
A new study by the American Cancer Society finds that racial disparities in cancer mortality result in significant economic losses, with $3.2 billion in lost earnings avoided in 2015 if non-Hispanic black cancer deaths and earning rates had been equal to those of non-Hispanic white cancer patients. The study highlights the importance o...
A new study found that personalized ovarian cancer risk prediction reduces cancer worry and anxiety in women. Participants who received the personalized risk estimate were more likely to take preventative action and reduce their risk of developing ovarian cancer.
A new saliva test has detected early throat cancer in a person with no symptoms, highlighting a potential breakthrough in cancer screening. The test identified HPV-DNA in the saliva of an infected individual, allowing for early removal of the affected tonsil through surgery.
A multicancer blood test safely detected 26 undiagnosed cancers and enabled potentially curative treatment in a study of over 9,900 women. The test was found to be complementary and additive to standard screening methods for detecting breast, colon, and lung tumors.
Researchers developed a multi-cancer blood test that detected some cancers, including ovarian cancers, and successfully screened for non-cancer causes before diagnostic tests. The test showed promise as a minimally invasive option to increase cancer detection rates in populations already following standard screening approaches.
A blood test developed by Thrive Earlier Detection Corp. has identified multiple cancers in over 10,000 women without a prior history of cancer. The study found that the test more than doubled the number of 'screen-detected' cancers, increasing from 25% to 52%.
A study found that using family history-based guidelines to identify individuals for early screening could help detect young-onset colorectal cancer. Researchers analyzed data from adults with and without colorectal cancer and estimated the potential impact of these guidelines on early detection and prevention.
A team of researchers used genome-wide CRISPR technology to identify RNA-binding proteins, including Staufen2, that sustain and protect drug-resistant leukemia stem cells. Loss of Staufen2 led to a reduction in leukemia growth and improved survival in mouse models.
A large observational study compared radiologists' recall rates and cancer detection in breast cancer screenings using digital breast tomosynthesis (DBT) and digital mammography. The study found that DBT had higher cancer detection rates but lower recall rates than digital mammography.
The blood test uses methylation patterns to detect cancer and identify its origin, achieving a 93% accuracy rate. It can detect over 50 cancer types, including the most deadly ones, with a low false positive rate of 0.7%, often before symptoms show up.
Researchers found that personalized cancer outreach using machine learning and targeted interventions can improve return on investment by 74-96%. The study used a randomized field experiment to analyze the effectiveness of different outreach programs, which varied in their impact depending on patient demographics and characteristics.
Researchers identified 15 potent tumor suppressor genes that, when mutated, triggered rapid growth of HNSCC in mice. These genes include ADAM10 and AJUBA, which are also mutated in human HNSCC. The study reveals the identity of rare driver mutations in tumor-suppressing genes using a mouse-based CRISPR screen.
A collaborative research team from Dartmouth and Honduras found a high level of participation in rural cancer screening events, resulting in over 88% of identified individuals seeking follow-up care. The 'multiphasic' approach involved multiple cancer screenings in one event, which was well-received by local communities.
A new study published in Radiology found that digital breast tomosynthesis (DBT) improved cancer detection rates and reduced false positives compared to digital mammography (DM). DBT screening detected a higher proportion of poor prognosis cancers than DM, with better visualization of lesions and reduced tissue superimposition.
A new study suggests that lengthening the time between prostate cancer screenings can significantly reduce overdiagnosis and improve outcomes. The research found that discontinuing screening at age 60 would greatly reduce overdiagnoses by 79-82%, but save fewer lives compared to screening until age 69.
Researchers found no association between opioid use and cancer screening, despite higher healthcare utilization among opioid users. Key cancer screenings were more common in women with frequent doctor visits regardless of opioid status.
Cancer survivors diagnosed between ages 15-20 have an increased risk of premature death and severe health conditions compared to siblings. The study highlights the need for long-term screening of young cancer survivors throughout their lives.
A study published in BMJ Sexual & Reproductive Health found that having 10 or more lifetime sexual partners is associated with a heightened risk of cancer diagnosis in both men and women. Women who reported this number were 91% more likely to be diagnosed, while those with limiting chronic conditions were 64% more likely. The study sug...
A new study from UNM Comprehensive Cancer Center scientists reveals that cervical cancer screening every three years is protective against cervical cancer. Most cancers are caught before spreading, making treatment easier. Screening was found to reduce localized and distant cancers.
Researchers found a significant spike in new colorectal cancer diagnoses between ages 49 and 50, indicating many latent cases were likely going undiagnosed until screening began. The majority of these cases (93%) were invasive, requiring aggressive treatment, including surgery.