Articles tagged with Cancer Screening
The study highlights the efficacy of Bluestar Genomics' 5-hmC signal detection technology for detecting breast, lung, pancreatic, and prostate cancer from a single blood draw. The technology demonstrated high performance in classifying samples with high Area Under the Curve measures.
Bowel cancer screening tests can miss patients due to NHS staff shortages, particularly in England where lower haemoglobin levels warrant further investigation. Cancer Research UK calls for significant investment to train and recruit more staff to diagnose patients earlier.
A new study finds that Australians are increasingly being diagnosed with harmless cancers, exposing them to unnecessary surgeries and chemotherapy. Overdiagnosis rates have increased significantly since 1982, with 24% of prostate cancers, 73% of thyroid cancers, and 58% of melanomas overdiagnosed in men.
Researchers at OHSU assess barriers to care in 10 preventive services, finding enhanced services like patient navigation increase cancer screening rates. Additional research is needed to better understand patient and provider barriers and the role of health information technology.
Thyroid cancer rates in the US have stabilized since 2014, with a decline in new cases per 100,000 people from 14.7 to 14.1 between 2009 and 2016. The rise in thyroid cancer was largely due to increased screening and imaging over the past three decades.
The study validated the reproducibility of CRISPR-Cas9 functional genetic screens, creating the largest genetic screen resource for cancer research. This combined dataset will help narrow down the list of targets for the next generation of cancer treatments, speeding up the discovery and development of new drugs.
Recent colorectal cancer screening rates more than doubled among people ages 45 to 49, a trend unique to this age group. The increase in screening was attributed to the release of updated American Cancer Society guidelines recommending screening in that age range.
The Cancer Prevention and Control Research Network has published a supplemental issue of Preventive Medicine highlighting disparities in cancer prevention and control. The research findings report on factors contributing to rural disparities and strategies to improve equity in cancer screening rates.
A new book published by international cancer experts offers promising research findings on Latino cancer and strategies for reducing health disparities. The book provides recommendations for creating studies based on subgroups and moving towards precision medicine to address the projected 142% rise in Latino cancer cases by 2030.
A new study found that biennial mammography screening resulted in smaller and less advanced breast cancer tumors compared to annual screenings. The study also discovered that women receiving biennial screenings tended to have more aggressive treatment options, such as chemotherapy and axillary lymph node dissection.
A study on cancer trends in Canada from 1971 to 2015 found an increase in breast and colorectal cancers among younger adults, particularly women aged 30-39. In contrast, cancer incidence has decreased in older age groups, with declines seen in cervical, lung, bladder, and prostate cancers across most age categories.
Scientists at UCLA Jonsson Comprehensive Cancer Center developed a new high-throughput screening system that identifies selective inhibitors of metabolic pathways. The approach revealed multiple kinase inhibitors block nucleotide metabolism and its targets.
A new study from the University of Pennsylvania School of Medicine found that implementing an electronic health record nudge increased cancer screening orders by 22% and 14%, respectively. However, the study also showed that patients' follow-through on screenings remained largely unchanged. The researchers suggest that future intervent...
A study published in The BMJ found substantial variation in bowel cancer rates after colonoscopies in England, with lower rates seen at NHS providers. Reducing this variation could prevent or diagnose more cancers earlier, the researchers suggest.
Research found that colonoscopy accuracy has improved overall in England, but variation between providers remains. The study suggests that some independent providers have higher rates of missed cancers compared to NHS providers.
Researchers found a 75% reduction in gastric cancer risk after eliminating Helicobacter pylori infection. Higher rates of gastric cancer were observed among African American, Asian, and Hispanic populations, as well as men who smoke.
A study found that cervical cancer screening rates decline among women aged 45-65, particularly those with lower education, rural residency, or lack of insurance. The study highlights the need for increased awareness and access to screenings for vulnerable populations.
Researchers aim to increase colorectal cancer screening and follow-up care among underserved individuals in Appalachia through a multi-institutional $5.7 million grant. The goal is to improve guideline-recommended screenings and healthcare services, particularly in rural communities where trust is a barrier.
New research found that women with diabetes are up to a quarter less likely to undergo recommended cancer screenings, including cervical, breast, and colorectal cancer tests. The study suggests that the burden of diabetes care management in primary care may contribute to lower uptake of cancer screening.
A recent study comparing digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) found that DBT significantly increased cancer detection rates for invasive, minimal, estrogen receptor-positive invasive, and node-negative cancers. However, the difference was not significant for ductal carcinoma in situ.
A new study presented at the IASLC 2019 North America Conference on Lung Cancer found that lung cancer screening guidelines are inadequate to diagnose patients who contract lung cancer from occupational exposure, including first responders. Low-dose computed tomography was shown to detect disease earlier in this population.
A 40-year epidemiological study found that cancer incidence and mortality rates often move in concert for certain cancers, such as lung cancer, indicating a desirable trend. However, other cancers like thyroid, kidney, and melanoma show rising incidence rates with stagnant mortality rates, suggesting overdiagnosis may be at play
Experts advise against routine bowel cancer testing for everyone aged 50-79 due to small benefits and potential harms. However, men and women with a risk of 3% or more in the next 15 years should consider screening.
A study published in the American Journal of Roentgenology found that ultrasound screening after digital mammography and digital breast tomosynthesis yielded no significant difference in additional cancer detection rate. The findings suggest that DBT does not obviate additional US screening for women with dense breast tissue.
The closure of nearly 100 women's health clinics in the US was associated with fewer cervical cancer screenings, more advanced diagnoses, and increased mortality rates. States with clinic closures saw a 2% drop in screenings, particularly among uninsured women, Hispanic women, and young adults.
New research from the University of South Australia shows that bowel cancer screening significantly reduces deaths. A study of 12,906 patients found that faecal occult blood testing and colonoscopies can catch the disease early, preventing 45% of cancer deaths.
Research found that only 35% of eligible women took part in all three screening programmes, with 10% remaining unscreened. Women from areas of less deprivation and those with caring duties were more likely to take up screenings, while practices with higher proportions of unemployed patients and smokers had lower rates.
A new study by the American Cancer Society finds that colorectal cancer incidence is increasing exclusively in young adults in nine high-income countries. The rates are rising in contrast to stable or declining trends in older adults, suggesting changes in early-life exposures are increasing CRC risk.
The American Society for Gastrointestinal Endoscopy has released an updated guideline on screening and surveillance of Barrett's esophagus, aiming to improve patient outcomes. The guideline addresses various endoscopic procedures and technologies used in screening and surveillance, including advanced imaging and sampling modalities.
A recent study by Brigham researchers found that sociodemographic factors, such as income and race, predict differences in oral cancer screening (OCS) rates. The results show that minority and low-income individuals are less likely to receive recommended OCS exams at dental visits, highlighting disparities in access to quality care.
The USPSTF recommends assessing risk in women with a history of breast, ovarian, fallopian tube, or peritoneal cancer, as well as those with an ancestry associated with BRCA1/2 mutations. Genetic counseling and testing are offered to those with a positive result after counseling.
A new study from Ryerson University assesses the link between premature mortality and environmental, socioeconomic, and demographic characteristics in Toronto's 140 neighborhoods. Neighborhoods with fewer trees, lower cancer screening rates, higher pollution levels, and lower income tend to have higher premature mortality rates.
The USPSTF continues to recommend against routine screening for pancreatic cancer in asymptomatic adults due to its poor prognosis. This recommendation is based on the limited effectiveness and potential harms of screening in this population.
Tiny devices based on microfluidics can analyze bodily fluids to detect early signs of cancer, enabling widespread screening. They also help develop personalized treatments by predicting patient responses to drug candidates.
A new study reveals a significantly higher prevalence of anal cancer precursors in women living with HIV compared to previous reports. The researchers recommend developing cost-effective detection and management strategies for this population.
Researchers studied clinician and older adult perspectives on communicating cancer screening cessation. Key findings include framing discussions around risks and benefits, patient empowerment, and addressing life expectancy concerns. The study aims to personalize cancer screening for elderly patients.
Researchers propose evaluating genomic analyzes in cervical cytologies to detect endometrial cancer at an early stage. Molecular tests can refine diagnostic algorithms and benefit asymptomatic women with a high risk of cancer.
A study by Brigham Young University found that viewing images of skin cancer and UV damage visuals significantly increases people's likelihood to screen themselves for cancer. The study used a variety of methods, including visual stimulation with images of moles being removed, to demonstrate the impact on behavior
A new study found that states that expanded Medicaid saw larger increases in colorectal cancer screening, with an additional 236,573 people screened. The study suggests that Medicaid expansion can improve cancer screening rates among low-income adults.
The rate of bowel cancer is rising among adults aged 20-49 in Europe, with the youngest age group experiencing the fastest rise. Rates are higher in North America, Australia and China compared to older adults.
A study found that cancer screening rates decrease as the day goes on for patients seen later in the day. Decision fatigue and overwhelmed clinicians may contribute to this trend, leading to lower completion rates for screenings like mammograms and colonoscopies.
A study of 33 practices found that physicians ordered fewer cancer screenings as the clinic day progressed, and patients completed them less often. Screening test order rates were highest at 8 a.m. and lowest at 5 p.m., suggesting timing may influence physician and patient behavior.
The American Cancer Society aims to lower overall cancer mortality 40% between 2015 and 2035, primarily through reducing risk factors like smoking and excess body weight. The goal is based on applying favorable cancer mortality trends among college graduates to the entire population.
A recent study published in Cancer Epidemiology, Biomarkers & Prevention found that the prevalence of physician-patient discussions about lung cancer screening is very low and declining. In 2017, only 4.3% of the general population discussed lung cancer screening with their doctor, compared to 8.7% among current smokers in 2012.
A team of University of Wisconsin-Madison scientists has identified four blood-based fingerprints associated with pre-cancerous forms of colon cancer. The findings may lead to a minimally-invasive blood test to increase screening rates and reduce overtreatment.
A study published in The BMJ found that routine HPV vaccination in Scotland led to a significant reduction in cervical disease among young women. Vaccinated women showed an 89% reduction in CIN grade 3 or worse, while unvaccinated women also experienced a decrease in disease, possibly due to herd protection.
A new study found that 3D mammography improves breast cancer detection in older women, with lower false-positive rates and higher positive predictive values. The results suggest that guidelines for screening in this age group should be based on individual preferences and health status.
Starting colorectal cancer screening at age 45 rather than 50 would decrease U.S. cancer deaths by as much as 11,100 over five years and cases by up to 29,400. Screening a greater number of older adults would avert nearly three times as many diagnoses and deaths at a lower cost.
New state laws recommending supplemental screening tests for women with dense breast tissue resulted in modestly boosted cancer detection rates, specifically increased breast ultrasound and cancer detection rates
A pilot study published in PNAS detects early-stage liver cancer in HBV carriers with high accuracy, using cell-free DNA and protein biomarkers. The HCCscreen assay achieves a 17% positive predictive value, 100% sensitivity, and 94% specificity.
A nationally representative study found that teenagers and young adults are more likely to use fruit- and candy-flavored e-cigarettes than their adult counterparts. The study also revealed that adolescent vapers were more likely to experiment with multiple flavor types, which may be a key factor in their vaping habits.
A new report emphasizes the importance of transforming healthcare delivery in the US to reduce cancer burden. The study identifies goals for a high-performing healthcare system, including access to primary care, timely evidence-based treatment, and patient-centered care.
A new study published in Pediatric Blood and Cancer found that early cancer surveillance in patients with Li-Fraumeni Syndrome is cost-effective, resulting in additional years of life. The research showed a significant increase in life expectancy for high-risk patients, with healthcare costs estimated at $17,000 per year gained.
A highly sensitive method for detecting cancer biomarkers in exosomes has been developed using molecular imprinting technology. The device, created by Kobe University researchers, can detect about 150 exosomes in 10 microliters and achieves unprecedented high-sensitivity detection of 6 picograms per milliliter.
A study by Brigham and Women's Hospital found that patients with primary care received more high-value care, such as cancer screening and diagnostic testing, and reported a better healthcare experience. Primary care was also associated with higher rates of recommended counseling services, including smoking cessation.
Americans with primary care receive more recommended cancer screenings, flu shots, and reported better patient experience compared to those without. Primary care also leads to better overall healthcare access.
A study at St. Michael's Hospital found that transgender patients have lower odds of being screened for certain types of cancer, including breast, cervical, and colorectal cancer. Transgender patients had a 70% lower odds of being screened for breast cancer, with similar disparities seen in cervical and colorectal cancer screening.
A population health study from IUPUI and Regenstrief Institute identified socioeconomic and racial disparities in health behaviors and screening for cancer in 34 Indiana counties. Black residents have lower cancer incidence but higher mortality rates, while those with low income and education face poor access to healthcare.
A new study found that complication rates following invasive lung cancer diagnostic tests are twice as high in the community setting compared to clinical trials, with associated downstream costs of $6,320 to $56,845 on average. The researchers emphasize the need for sharing risks with patients considering lung cancer screening.
A study by the University of Colorado Anschutz Medical Campus found that Facebook advertising can effectively reach rural communities with information and reminders about cancer screening. The EndCancer initiative resulted in a high engagement rate, with 96% of participants staying enrolled.