Survivors of childhood Hodgkin lymphoma are at a significantly increased risk of developing various types of solid tumors over the long term. Certain subgroups of patients have an even higher risk, and these findings may help refine guidelines for cancer screening in Hodgkin lymphoma survivors.
A recent study published in the journal Radiology found that digital mammography significantly increased breast cancer detection by 14 percent compared to screen film mammography. The technology improved detection of early-stage cancers, including ductal carcinoma in situ, without increasing recall rates.
A program providing individually tailored lifestyle recommendations for patients undergoing colorectal cancer screening helped encourage healthy behavior, according to a study published in Cancer Epidemiology, Biomarkers & Prevention. Participants who received tailored feedback increased their cancer preventive behaviors by 0.11 compar...
A new report from the American Cancer Society proposes key areas to advance cancer screening's contribution to cancer control. Research is needed to improve existing screening modalities, quality and performance of current tests, and develop new strategies for cancers amendable to screening.
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A new study from St. Michael's Hospital found that phone calls were more effective than mailed letters in encouraging patients overdue for cancer screening to receive tests. Phone calls resulted in a 25% increase in screening rates compared to letters, particularly among women and men.
Women carrying rare breast cancer variants are more likely to develop interval breast cancers, which are often aggressive and lethal. The study found that these women have a higher risk of death from breast cancer compared to those with common mutations.
A recent survey found that social vulnerability and medical skepticism are major barriers to cancer screening participation, particularly for colorectal and lung cancer screenings. Researchers call for a combined approach incorporating new technologies and personalized messaging to address inequalities in screening uptake.
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A major clinical study in Sweden has shown that 3D mammography detects over 30% more cancers compared to traditional mammography. The method uses low-dose x-ray images from different angles, resulting in higher image quality and increased cancer detection rates.
A new study finds that baseline PSA levels in black men between 40 and 60 can strongly predict future development of prostate cancer and its most aggressive forms. Elevated PSA levels are associated with increased risk, even among those within the normal range.
A study of 50,000 people found that over 80% of those with identifiable genetic risk for breast, ovarian, prostate, and pancreatic cancer are unaware they carry the gene. The findings highlight the need for effective DNA-based screening to identify high-risk individuals before a cancer diagnosis.
A Danish-Norwegian study found that breast cancer mortality is declining due to better treatment, not screening. The study challenges the effectiveness of breast cancer screening programs, suggesting alternative methods like palpation.
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Despite the risk of a 25% lower mortality rate, many people aged 60 and above are missing out on lifesaving bowel cancer screening. Inequalities in the system have widened, with those from deprived areas and ethnically diverse neighbourhoods being less likely to participate.
The ACCION program has increased screening rates in West Texas to around 50 percent, compared to a national average of about 70 percent. The program's success is attributed to its use of promotoras and partnerships with community organizations to make screenings more accessible.
A study by University of Colorado Anschutz Medical Campus found that doctors with personal cancer experience are 17% more likely to recommend ovarian cancer screening to low-risk women, despite guidelines against it. This bias may be due to overestimating a patient's risk and prioritizing their experience over evidence-based guidelines.
A study by researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found that doctor-patient discussions about lung cancer screening are often brief and one-sided, failing to address potential harms. The conversation quality was rated as poor, with only a few minutes spent discussing the issue on average.
At least 1% of the US population has an identifiable genetic risk for cancer or heart disease that can be detected through genomic screening. Implementing routine genomic screening could lead to significant benefits, but more work is needed to develop functioning models.
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A recent study found that patients who smoke often misunderstand the benefits and limitations of lung cancer screenings. While LDCT scans can lower mortality rates, they do not reduce the risk of developing lung cancer. Quitting smoking remains the most effective way to prevent this disease.
The American Cancer Society and NFL have awarded $3.2 million in grant funding to address breast cancer disparities among women of color. The grants will support timely access to follow-up care and high-quality breast cancer screening for underserved women.
The American Cancer Society is outlining its vision for cancer control in the decades ahead, aiming to eliminate socioeconomic disparity to prevent one in four cancer deaths in the US. The blueprint identifies key areas such as prevention, screening, and early detection, and emphasizes the need to address disparities in cancer outcomes.
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A new study found that younger patients (under 50) diagnosed with rectal cancer do not experience a survival benefit from chemotherapy, radiation, and surgery. The findings suggest early onset disease may differ in terms of biology and response to therapy.
Developing cancer was associated with an increased risk of new type 2 diabetes, even after accounting for precancer risk factors. The risk was highest in the first two years after diagnosis.
The American Cancer Society recommends earlier colorectal cancer screening for average-risk adults beginning at age 45, based on research showing an increased incidence of CRC in younger adults. Colorectal cancer incidence has declined steadily over the past two decades in people 55 and older due to screening.
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Colorectal cancer screening may need to be started earlier than previously recommended, with a new study suggesting starting at age 45. Researchers estimate that cutting mortality from colorectal cancer could save up to 70% of lives if everyone followed the revised guidelines.
A recent study published in BMC Medicine found that the negative effects of screen time on cardiovascular disease, cancer incidence, and mortality are more pronounced in people with lower levels of fitness and physical activity. Increasing strength and fitness may offset these risks, suggesting a targeted approach to reducing screen ti...
A new study reveals declines in prostate cancer screening and diagnoses in the US between 2008-2014, with significant decreases in definitive treatments. The findings suggest that men are choosing active surveillance for low-risk prostate cancer, avoiding treatment-related harms.
A study by UCSF and Mayo Clinic found that automated breast-density evaluation is as accurate as subjective evaluation done by radiologists in predicting breast cancer risk. Women with dense breasts are more likely to be diagnosed with advanced-stage breast cancers.
Automated BI-RADS breast density measures have similar predictive ability to clinical assessments, but may be more reproducible and suitable for identifying women at high risk of interval cancer. Hospital readmissions within the first week are more likely preventable than those occurring later, suggesting a shift in accountability model.
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Research suggests that individuals with false-positive cancer screening test results are more likely to participate in future recommended screenings. Women with previous false-positive mammograms were at least 43% more likely to obtain future breast cancer screenings, while men with false-positive prostate cancer screenings were at lea...
Researchers have developed primary pancreatic organoid tumor models using magnetic nanoparticle assembly, enabling high-throughput phenotypic drug screening. These 3D structures allow for the testing of drug-like molecules against patient-derived cancer cells, providing insights into potential patient outcomes.
A $15.5 million NCI grant creates a center at five health systems to improve lung cancer screening and address disparities in early diagnosis, treatment, and mortality. The center will develop a shared model data for research on optimizing precision lung cancer screening.
Researchers have discovered a faster, more cost-effective way to determine which DNA mutations cause human bowel cancer. A new preclinical pipeline uses gene editing technology (CRISPR) to rapidly engineer normal colon cells with DNA changes, allowing for real-time monitoring of growing cancers.
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Priya Prasad, MD, has received the David L. Rimoin Inspiring Excellence Award for her platform presentation on population-based hereditary cancer risk assessment during screening mammography. The award recognizes her commitment to enhancing the appropriate utilization of screening for hereditary cancers.
A study of 30,352 US adults found that indoor tanning is associated with a higher risk of melanoma and keratinocyte skin cancers. The results highlight the need for regular skin cancer screening among indoor tanners, who are at increased risk due to their exposure to UV radiation.
A new study finds that establishing a minimum recall rate for breast cancer screening programs can help balance the risk of missing invasive cancers and the cost of additional testing. The study analyzed data from the UK Breast Cancer Service Screening Program, finding that lower recall rates correlate with higher interval cancer rates.
Researchers developed a new screening test for endometrial and ovarian cancers using cervical fluid samples from routine Pap tests. The test, called PapSEEK, detected cancer cells in 81% of endometrial and 33% of ovarian cancers, with improved sensitivity when using different sampling methods.
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A new study by Dartmouth Health suggests that e-cigarette use may be more harmful than beneficial, particularly among adolescents and young adults. The research found that e-cigarettes could lead to over 1.5 million years of life lost due to increased smoking rates among youth.
A study presented at the ARRS 2018 Annual Meeting found that screening mammography in women aged 40-49 detects 19.3% more cancers than in older age groups, but also increases callbacks and biopsies by 1.5% and 0.1%, respectively.
A new iPad app, mPATH-CRC, was developed to improve colon cancer screening rates. The app simplified the process of ordering a screening test, increasing screenings from 15% to 30% among participants. While the app showed promise, it is not intended to replace doctors' care, but rather to augment it and encourage patient participation.
A new clinical trial using a tailored intervention may minimize lung cancer occurrence and mortality rates for those at higher risk. The study will compare the effectiveness of counseling, nicotine replacement therapy, and gain-framed text messaging in supporting high-risk smokers who want to quit.
The US Preventive Services Task Force recommends against screening for ovarian cancer in women without symptoms and at low risk. The task force found that the harms of screening, including unnecessary surgery, outweigh its benefits.
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A study found that screening the general population for cancer genes is cost-effective, preventing more breast and ovarian cancers. This approach could lead to thousands fewer cases of these cancers, particularly among women over 30.
The CancerSEEK test is a noninvasive, multianalyte test that evaluates levels of eight cancer proteins and the presence of cancer gene mutations in the blood. The test has greater than 99% specificity for cancer and can identify the location of tumors with high accuracy.
The NHS bowel scope screening programme saw a significant increase in uptake when patients were sent additional reminders addressing common concerns, highlighting the importance of patient information and support., Bowel cancer is the 4th most common cancer in the UK, with over half of cases diagnosed at a late stage.
A new study from the University of Gothenburg suggests that higher education and income are key factors determining whether women participate in cervical screening. The study, which analyzed data from over 581,000 women, found that country of birth was not a significant factor in participation rates.
A research team at Rush University Medical Center is working on a simple blood test to detect non-small cell lung cancer with 90% accuracy. The goal is to identify biomarkers that can detect the disease earlier and reduce late-stage diagnoses, improving treatment outcomes.
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A study found that bi-annual dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) exams were more effective in detecting breast cancer in younger women with a high-risk genetic profile than an annual mammogram. The intensive surveillance strategy reduced anxiety levels and improved quality of life for participants.
A study published by Springer found that many women with high breast cancer risk are not receiving MRI scans, while those at lower risk are being screened too frequently. This highlights a missed opportunity to use technology that can help detect breast cancer early in high-risk groups.
A new study suggests that an American Cancer Society program has been effective in promoting improvements in colorectal cancer screening rates in federally qualified health centers. Funded FQHCs increased their CRC screening rates significantly more than nonfunded FQHCs, with increases of 8.7% and 12.7% over three years.
Researchers found that abbreviated breast MRI (AB-MR) detected five additional cancers in asymptomatic women with dense breast tissue after a negative mammogram. AB-MR may be a better option than whole breast ultrasound for supplemental screening.
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A study found that only 20% of Indonesian women are aware of cervical smears, with even lower rates for mammography. Higher education, household expenditure, and health insurance were associated with increased awareness and participation. Experts call for improved education and access to resources to increase cancer screening rates.
A new study finds that HPV testing is more sensitive than the Pap test for detecting precancerous cells. Cotesting, which combines both methods, identified more cases of treatable cancer but only affected a small number of women.
A new study found significant disparities in survival rates for patients with different types of human papillomavirus (HPV)-associated cancers. The findings highlight the need for improved HPV vaccination, cancer screening, and treatment access to address these disparities.
Gender disparities are identified in lung cancer screening and care, with more female patients meeting high-risk criteria but not completing low-dose CT scans. Language barriers do not delay initiation of lung cancer care, according to a second study.
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A study published in Annals of Oncology found that men who smoke and have multiple oral sex partners are at higher risk of developing oropharyngeal cancer. Despite the risk, the likelihood is still relatively low, making screening a challenge.
The Terry Fox Research Institute study found that the Pan Can Lung Cancer Risk Prediction Model outperformed comparable models in detecting early-stage lung cancer. The model identified high-risk individuals and detected cancer early, saving lives.
A community-based intervention called c-CARE improved cancer literacy and reduced disparate lung cancer outcomes among minority communities. The study found that participants showed increased knowledge and self-efficacy for lung cancer screening, but not perceived susceptibility.
A new study by American Cancer Society investigators finds workers at organizations with fewer than 25 employees are less likely to have been screened for three cancers. After adjusting for socioeconomic factors and insurance status, most of the difference in screening rates disappears.
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A new study found that women with disabilities are less likely to participate in breast and bowel cancer screenings due to practical barriers. Women with multiple disabilities or those without access to a car were particularly affected.
Experts from United European Gastroenterology call on European governments to develop early detection techniques for digestive cancers, including faecal microbiota screening and gastric cancer screening. The aim is to improve outcomes and save thousands of European lives.
A re-analysis of USPSTF evidence suggests flexible sigmoidoscopy may reduce all-cause mortality, contrary to previous guidelines. Researchers found that looking at cohorts as separate trials, rather than aggregating them, strengthened the evidence supporting screening with flexible sigmoidoscopy.