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Highly sensitive method to detect potential cancer biomarker

A highly sensitive method for detecting cancer biomarkers in exosomes has been developed using molecular imprinting technology. The device, created by Kobe University researchers, can detect about 150 exosomes in 10 microliters and achieves unprecedented high-sensitivity detection of 6 picograms per milliliter.

SourceKobe University·JournalAngewandte Chemie International Edition·DateJan 30, 2019

Patients who identify as transgender have lower odds of being screened for cancer: Study

A study at St. Michael's Hospital found that transgender patients have lower odds of being screened for certain types of cancer, including breast, cervical, and colorectal cancer. Transgender patients had a 70% lower odds of being screened for breast cancer, with similar disparities seen in cervical and colorectal cancer screening.

SourceSt. Michael's Hospital·JournalCanadian Family Physician·DateJan 23, 2019

Complication rates and costs of invasive lung cancer diagnostic tests may be higher than anticipated

A new study found that complication rates following invasive lung cancer diagnostic tests are twice as high in the community setting compared to clinical trials, with associated downstream costs of $6,320 to $56,845 on average. The researchers emphasize the need for sharing risks with patients considering lung cancer screening.

SourceUniversity of Texas M. D. Anderson Cancer Center·JournalJAMA Internal Medicine·DateJan 14, 2019

Social vulnerability and medical skepticism top factors limiting adherence to screening

A recent survey found that social vulnerability and medical skepticism are major barriers to cancer screening participation, particularly for colorectal and lung cancer screenings. Researchers call for a combined approach incorporating new technologies and personalized messaging to address inequalities in screening uptake.

SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateOct 19, 2018

Eight of 10 people with cancer risk genes don't know it

A study of 50,000 people found that over 80% of those with identifiable genetic risk for breast, ovarian, prostate, and pancreatic cancer are unaware they carry the gene. The findings highlight the need for effective DNA-based screening to identify high-risk individuals before a cancer diagnosis.

SourceYale University·JournalJAMA Network Open·DateSep 21, 2018

Doctor-patient discussions neglect potential harms of lung cancer screening, study finds

A study by researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found that doctor-patient discussions about lung cancer screening are often brief and one-sided, failing to address potential harms. The conversation quality was rated as poor, with only a few minutes spent discussing the issue on average.

SourceUNC Lineberger Comprehensive Cancer Center·JournalJAMA Internal Medicine·DateAug 13, 2018

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

Researchers have developed primary pancreatic organoid tumor models using magnetic nanoparticle assembly, enabling high-throughput phenotypic drug screening. These 3D structures allow for the testing of drug-like molecules against patient-derived cancer cells, providing insights into potential patient outcomes.