A new study from Ryerson University assesses the link between premature mortality and environmental, socioeconomic, and demographic characteristics in Toronto's 140 neighborhoods. Neighborhoods with fewer trees, lower cancer screening rates, higher pollution levels, and lower income tend to have higher premature mortality rates.
The USPSTF continues to recommend against routine screening for pancreatic cancer in asymptomatic adults due to its poor prognosis. This recommendation is based on the limited effectiveness and potential harms of screening in this population.
Tiny devices based on microfluidics can analyze bodily fluids to detect early signs of cancer, enabling widespread screening. They also help develop personalized treatments by predicting patient responses to drug candidates.
A new study reveals a significantly higher prevalence of anal cancer precursors in women living with HIV compared to previous reports. The researchers recommend developing cost-effective detection and management strategies for this population.
Researchers studied clinician and older adult perspectives on communicating cancer screening cessation. Key findings include framing discussions around risks and benefits, patient empowerment, and addressing life expectancy concerns. The study aims to personalize cancer screening for elderly patients.
Researchers propose evaluating genomic analyzes in cervical cytologies to detect endometrial cancer at an early stage. Molecular tests can refine diagnostic algorithms and benefit asymptomatic women with a high risk of cancer.
A study by Brigham Young University found that viewing images of skin cancer and UV damage visuals significantly increases people's likelihood to screen themselves for cancer. The study used a variety of methods, including visual stimulation with images of moles being removed, to demonstrate the impact on behavior
A new study found that states that expanded Medicaid saw larger increases in colorectal cancer screening, with an additional 236,573 people screened. The study suggests that Medicaid expansion can improve cancer screening rates among low-income adults.
The rate of bowel cancer is rising among adults aged 20-49 in Europe, with the youngest age group experiencing the fastest rise. Rates are higher in North America, Australia and China compared to older adults.
A study found that cancer screening rates decrease as the day goes on for patients seen later in the day. Decision fatigue and overwhelmed clinicians may contribute to this trend, leading to lower completion rates for screenings like mammograms and colonoscopies.
A study of 33 practices found that physicians ordered fewer cancer screenings as the clinic day progressed, and patients completed them less often. Screening test order rates were highest at 8 a.m. and lowest at 5 p.m., suggesting timing may influence physician and patient behavior.
The American Cancer Society aims to lower overall cancer mortality 40% between 2015 and 2035, primarily through reducing risk factors like smoking and excess body weight. The goal is based on applying favorable cancer mortality trends among college graduates to the entire population.
A recent study published in Cancer Epidemiology, Biomarkers & Prevention found that the prevalence of physician-patient discussions about lung cancer screening is very low and declining. In 2017, only 4.3% of the general population discussed lung cancer screening with their doctor, compared to 8.7% among current smokers in 2012.
A team of University of Wisconsin-Madison scientists has identified four blood-based fingerprints associated with pre-cancerous forms of colon cancer. The findings may lead to a minimally-invasive blood test to increase screening rates and reduce overtreatment.
A study published in The BMJ found that routine HPV vaccination in Scotland led to a significant reduction in cervical disease among young women. Vaccinated women showed an 89% reduction in CIN grade 3 or worse, while unvaccinated women also experienced a decrease in disease, possibly due to herd protection.
A new study found that 3D mammography improves breast cancer detection in older women, with lower false-positive rates and higher positive predictive values. The results suggest that guidelines for screening in this age group should be based on individual preferences and health status.
Starting colorectal cancer screening at age 45 rather than 50 would decrease U.S. cancer deaths by as much as 11,100 over five years and cases by up to 29,400. Screening a greater number of older adults would avert nearly three times as many diagnoses and deaths at a lower cost.
New state laws recommending supplemental screening tests for women with dense breast tissue resulted in modestly boosted cancer detection rates, specifically increased breast ultrasound and cancer detection rates
A pilot study published in PNAS detects early-stage liver cancer in HBV carriers with high accuracy, using cell-free DNA and protein biomarkers. The HCCscreen assay achieves a 17% positive predictive value, 100% sensitivity, and 94% specificity.
A nationally representative study found that teenagers and young adults are more likely to use fruit- and candy-flavored e-cigarettes than their adult counterparts. The study also revealed that adolescent vapers were more likely to experiment with multiple flavor types, which may be a key factor in their vaping habits.
A new report emphasizes the importance of transforming healthcare delivery in the US to reduce cancer burden. The study identifies goals for a high-performing healthcare system, including access to primary care, timely evidence-based treatment, and patient-centered care.
A new study published in Pediatric Blood and Cancer found that early cancer surveillance in patients with Li-Fraumeni Syndrome is cost-effective, resulting in additional years of life. The research showed a significant increase in life expectancy for high-risk patients, with healthcare costs estimated at $17,000 per year gained.
A highly sensitive method for detecting cancer biomarkers in exosomes has been developed using molecular imprinting technology. The device, created by Kobe University researchers, can detect about 150 exosomes in 10 microliters and achieves unprecedented high-sensitivity detection of 6 picograms per milliliter.
Americans with primary care receive more recommended cancer screenings, flu shots, and reported better patient experience compared to those without. Primary care also leads to better overall healthcare access.
A study by Brigham and Women's Hospital found that patients with primary care received more high-value care, such as cancer screening and diagnostic testing, and reported a better healthcare experience. Primary care was also associated with higher rates of recommended counseling services, including smoking cessation.
A study at St. Michael's Hospital found that transgender patients have lower odds of being screened for certain types of cancer, including breast, cervical, and colorectal cancer. Transgender patients had a 70% lower odds of being screened for breast cancer, with similar disparities seen in cervical and colorectal cancer screening.
A population health study from IUPUI and Regenstrief Institute identified socioeconomic and racial disparities in health behaviors and screening for cancer in 34 Indiana counties. Black residents have lower cancer incidence but higher mortality rates, while those with low income and education face poor access to healthcare.
A new study found that complication rates following invasive lung cancer diagnostic tests are twice as high in the community setting compared to clinical trials, with associated downstream costs of $6,320 to $56,845 on average. The researchers emphasize the need for sharing risks with patients considering lung cancer screening.
A study by the University of Colorado Anschutz Medical Campus found that Facebook advertising can effectively reach rural communities with information and reminders about cancer screening. The EndCancer initiative resulted in a high engagement rate, with 96% of participants staying enrolled.
Survivors of childhood Hodgkin lymphoma are at a significantly increased risk of developing various types of solid tumors over the long term. Certain subgroups of patients have an even higher risk, and these findings may help refine guidelines for cancer screening in Hodgkin lymphoma survivors.
A recent study published in the journal Radiology found that digital mammography significantly increased breast cancer detection by 14 percent compared to screen film mammography. The technology improved detection of early-stage cancers, including ductal carcinoma in situ, without increasing recall rates.
A program providing individually tailored lifestyle recommendations for patients undergoing colorectal cancer screening helped encourage healthy behavior, according to a study published in Cancer Epidemiology, Biomarkers & Prevention. Participants who received tailored feedback increased their cancer preventive behaviors by 0.11 compar...
A new report from the American Cancer Society proposes key areas to advance cancer screening's contribution to cancer control. Research is needed to improve existing screening modalities, quality and performance of current tests, and develop new strategies for cancers amendable to screening.
A new study from St. Michael's Hospital found that phone calls were more effective than mailed letters in encouraging patients overdue for cancer screening to receive tests. Phone calls resulted in a 25% increase in screening rates compared to letters, particularly among women and men.
Women carrying rare breast cancer variants are more likely to develop interval breast cancers, which are often aggressive and lethal. The study found that these women have a higher risk of death from breast cancer compared to those with common mutations.
A recent survey found that social vulnerability and medical skepticism are major barriers to cancer screening participation, particularly for colorectal and lung cancer screenings. Researchers call for a combined approach incorporating new technologies and personalized messaging to address inequalities in screening uptake.
A major clinical study in Sweden has shown that 3D mammography detects over 30% more cancers compared to traditional mammography. The method uses low-dose x-ray images from different angles, resulting in higher image quality and increased cancer detection rates.
A new study finds that baseline PSA levels in black men between 40 and 60 can strongly predict future development of prostate cancer and its most aggressive forms. Elevated PSA levels are associated with increased risk, even among those within the normal range.
A study of 50,000 people found that over 80% of those with identifiable genetic risk for breast, ovarian, prostate, and pancreatic cancer are unaware they carry the gene. The findings highlight the need for effective DNA-based screening to identify high-risk individuals before a cancer diagnosis.
A Danish-Norwegian study found that breast cancer mortality is declining due to better treatment, not screening. The study challenges the effectiveness of breast cancer screening programs, suggesting alternative methods like palpation.
Despite the risk of a 25% lower mortality rate, many people aged 60 and above are missing out on lifesaving bowel cancer screening. Inequalities in the system have widened, with those from deprived areas and ethnically diverse neighbourhoods being less likely to participate.
The ACCION program has increased screening rates in West Texas to around 50 percent, compared to a national average of about 70 percent. The program's success is attributed to its use of promotoras and partnerships with community organizations to make screenings more accessible.
A study by University of Colorado Anschutz Medical Campus found that doctors with personal cancer experience are 17% more likely to recommend ovarian cancer screening to low-risk women, despite guidelines against it. This bias may be due to overestimating a patient's risk and prioritizing their experience over evidence-based guidelines.
A study by researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found that doctor-patient discussions about lung cancer screening are often brief and one-sided, failing to address potential harms. The conversation quality was rated as poor, with only a few minutes spent discussing the issue on average.
At least 1% of the US population has an identifiable genetic risk for cancer or heart disease that can be detected through genomic screening. Implementing routine genomic screening could lead to significant benefits, but more work is needed to develop functioning models.
A recent study found that patients who smoke often misunderstand the benefits and limitations of lung cancer screenings. While LDCT scans can lower mortality rates, they do not reduce the risk of developing lung cancer. Quitting smoking remains the most effective way to prevent this disease.
The American Cancer Society and NFL have awarded $3.2 million in grant funding to address breast cancer disparities among women of color. The grants will support timely access to follow-up care and high-quality breast cancer screening for underserved women.
The American Cancer Society is outlining its vision for cancer control in the decades ahead, aiming to eliminate socioeconomic disparity to prevent one in four cancer deaths in the US. The blueprint identifies key areas such as prevention, screening, and early detection, and emphasizes the need to address disparities in cancer outcomes.
A new study found that younger patients (under 50) diagnosed with rectal cancer do not experience a survival benefit from chemotherapy, radiation, and surgery. The findings suggest early onset disease may differ in terms of biology and response to therapy.
Developing cancer was associated with an increased risk of new type 2 diabetes, even after accounting for precancer risk factors. The risk was highest in the first two years after diagnosis.
The American Cancer Society recommends earlier colorectal cancer screening for average-risk adults beginning at age 45, based on research showing an increased incidence of CRC in younger adults. Colorectal cancer incidence has declined steadily over the past two decades in people 55 and older due to screening.
Colorectal cancer screening may need to be started earlier than previously recommended, with a new study suggesting starting at age 45. Researchers estimate that cutting mortality from colorectal cancer could save up to 70% of lives if everyone followed the revised guidelines.
A recent study published in BMC Medicine found that the negative effects of screen time on cardiovascular disease, cancer incidence, and mortality are more pronounced in people with lower levels of fitness and physical activity. Increasing strength and fitness may offset these risks, suggesting a targeted approach to reducing screen ti...
A new study reveals declines in prostate cancer screening and diagnoses in the US between 2008-2014, with significant decreases in definitive treatments. The findings suggest that men are choosing active surveillance for low-risk prostate cancer, avoiding treatment-related harms.
A study by UCSF and Mayo Clinic found that automated breast-density evaluation is as accurate as subjective evaluation done by radiologists in predicting breast cancer risk. Women with dense breasts are more likely to be diagnosed with advanced-stage breast cancers.
Automated BI-RADS breast density measures have similar predictive ability to clinical assessments, but may be more reproducible and suitable for identifying women at high risk of interval cancer. Hospital readmissions within the first week are more likely preventable than those occurring later, suggesting a shift in accountability model.
Research suggests that individuals with false-positive cancer screening test results are more likely to participate in future recommended screenings. Women with previous false-positive mammograms were at least 43% more likely to obtain future breast cancer screenings, while men with false-positive prostate cancer screenings were at lea...
Researchers have developed primary pancreatic organoid tumor models using magnetic nanoparticle assembly, enabling high-throughput phenotypic drug screening. These 3D structures allow for the testing of drug-like molecules against patient-derived cancer cells, providing insights into potential patient outcomes.
Researchers have discovered a faster, more cost-effective way to determine which DNA mutations cause human bowel cancer. A new preclinical pipeline uses gene editing technology (CRISPR) to rapidly engineer normal colon cells with DNA changes, allowing for real-time monitoring of growing cancers.
A $15.5 million NCI grant creates a center at five health systems to improve lung cancer screening and address disparities in early diagnosis, treatment, and mortality. The center will develop a shared model data for research on optimizing precision lung cancer screening.