Articles tagged with Cancer Screening
Colorectal cancer screening may need to be started earlier than previously recommended, with a new study suggesting starting at age 45. Researchers estimate that cutting mortality from colorectal cancer could save up to 70% of lives if everyone followed the revised guidelines.
A recent study published in BMC Medicine found that the negative effects of screen time on cardiovascular disease, cancer incidence, and mortality are more pronounced in people with lower levels of fitness and physical activity. Increasing strength and fitness may offset these risks, suggesting a targeted approach to reducing screen ti...
A new study reveals declines in prostate cancer screening and diagnoses in the US between 2008-2014, with significant decreases in definitive treatments. The findings suggest that men are choosing active surveillance for low-risk prostate cancer, avoiding treatment-related harms.
Automated BI-RADS breast density measures have similar predictive ability to clinical assessments, but may be more reproducible and suitable for identifying women at high risk of interval cancer. Hospital readmissions within the first week are more likely preventable than those occurring later, suggesting a shift in accountability model.
A study by UCSF and Mayo Clinic found that automated breast-density evaluation is as accurate as subjective evaluation done by radiologists in predicting breast cancer risk. Women with dense breasts are more likely to be diagnosed with advanced-stage breast cancers.
Research suggests that individuals with false-positive cancer screening test results are more likely to participate in future recommended screenings. Women with previous false-positive mammograms were at least 43% more likely to obtain future breast cancer screenings, while men with false-positive prostate cancer screenings were at lea...
Researchers have developed primary pancreatic organoid tumor models using magnetic nanoparticle assembly, enabling high-throughput phenotypic drug screening. These 3D structures allow for the testing of drug-like molecules against patient-derived cancer cells, providing insights into potential patient outcomes.
A $15.5 million NCI grant creates a center at five health systems to improve lung cancer screening and address disparities in early diagnosis, treatment, and mortality. The center will develop a shared model data for research on optimizing precision lung cancer screening.
Researchers have discovered a faster, more cost-effective way to determine which DNA mutations cause human bowel cancer. A new preclinical pipeline uses gene editing technology (CRISPR) to rapidly engineer normal colon cells with DNA changes, allowing for real-time monitoring of growing cancers.
Priya Prasad, MD, has received the David L. Rimoin Inspiring Excellence Award for her platform presentation on population-based hereditary cancer risk assessment during screening mammography. The award recognizes her commitment to enhancing the appropriate utilization of screening for hereditary cancers.
A study of 30,352 US adults found that indoor tanning is associated with a higher risk of melanoma and keratinocyte skin cancers. The results highlight the need for regular skin cancer screening among indoor tanners, who are at increased risk due to their exposure to UV radiation.
A new study finds that establishing a minimum recall rate for breast cancer screening programs can help balance the risk of missing invasive cancers and the cost of additional testing. The study analyzed data from the UK Breast Cancer Service Screening Program, finding that lower recall rates correlate with higher interval cancer rates.
Researchers developed a new screening test for endometrial and ovarian cancers using cervical fluid samples from routine Pap tests. The test, called PapSEEK, detected cancer cells in 81% of endometrial and 33% of ovarian cancers, with improved sensitivity when using different sampling methods.
A new study by Dartmouth Health suggests that e-cigarette use may be more harmful than beneficial, particularly among adolescents and young adults. The research found that e-cigarettes could lead to over 1.5 million years of life lost due to increased smoking rates among youth.
A study presented at the ARRS 2018 Annual Meeting found that screening mammography in women aged 40-49 detects 19.3% more cancers than in older age groups, but also increases callbacks and biopsies by 1.5% and 0.1%, respectively.
A new iPad app, mPATH-CRC, was developed to improve colon cancer screening rates. The app simplified the process of ordering a screening test, increasing screenings from 15% to 30% among participants. While the app showed promise, it is not intended to replace doctors' care, but rather to augment it and encourage patient participation.
A new clinical trial using a tailored intervention may minimize lung cancer occurrence and mortality rates for those at higher risk. The study will compare the effectiveness of counseling, nicotine replacement therapy, and gain-framed text messaging in supporting high-risk smokers who want to quit.
The US Preventive Services Task Force recommends against screening for ovarian cancer in women without symptoms and at low risk. The task force found that the harms of screening, including unnecessary surgery, outweigh its benefits.
A study found that screening the general population for cancer genes is cost-effective, preventing more breast and ovarian cancers. This approach could lead to thousands fewer cases of these cancers, particularly among women over 30.
The CancerSEEK test is a noninvasive, multianalyte test that evaluates levels of eight cancer proteins and the presence of cancer gene mutations in the blood. The test has greater than 99% specificity for cancer and can identify the location of tumors with high accuracy.
The NHS bowel scope screening programme saw a significant increase in uptake when patients were sent additional reminders addressing common concerns, highlighting the importance of patient information and support., Bowel cancer is the 4th most common cancer in the UK, with over half of cases diagnosed at a late stage.
A new study from the University of Gothenburg suggests that higher education and income are key factors determining whether women participate in cervical screening. The study, which analyzed data from over 581,000 women, found that country of birth was not a significant factor in participation rates.
A research team at Rush University Medical Center is working on a simple blood test to detect non-small cell lung cancer with 90% accuracy. The goal is to identify biomarkers that can detect the disease earlier and reduce late-stage diagnoses, improving treatment outcomes.
A study found that bi-annual dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) exams were more effective in detecting breast cancer in younger women with a high-risk genetic profile than an annual mammogram. The intensive surveillance strategy reduced anxiety levels and improved quality of life for participants.
A study published by Springer found that many women with high breast cancer risk are not receiving MRI scans, while those at lower risk are being screened too frequently. This highlights a missed opportunity to use technology that can help detect breast cancer early in high-risk groups.
A new study suggests that an American Cancer Society program has been effective in promoting improvements in colorectal cancer screening rates in federally qualified health centers. Funded FQHCs increased their CRC screening rates significantly more than nonfunded FQHCs, with increases of 8.7% and 12.7% over three years.
Researchers found that abbreviated breast MRI (AB-MR) detected five additional cancers in asymptomatic women with dense breast tissue after a negative mammogram. AB-MR may be a better option than whole breast ultrasound for supplemental screening.
A study found that only 20% of Indonesian women are aware of cervical smears, with even lower rates for mammography. Higher education, household expenditure, and health insurance were associated with increased awareness and participation. Experts call for improved education and access to resources to increase cancer screening rates.
A new study finds that HPV testing is more sensitive than the Pap test for detecting precancerous cells. Cotesting, which combines both methods, identified more cases of treatable cancer but only affected a small number of women.
A new study found significant disparities in survival rates for patients with different types of human papillomavirus (HPV)-associated cancers. The findings highlight the need for improved HPV vaccination, cancer screening, and treatment access to address these disparities.
Gender disparities are identified in lung cancer screening and care, with more female patients meeting high-risk criteria but not completing low-dose CT scans. Language barriers do not delay initiation of lung cancer care, according to a second study.
The Terry Fox Research Institute study found that the Pan Can Lung Cancer Risk Prediction Model outperformed comparable models in detecting early-stage lung cancer. The model identified high-risk individuals and detected cancer early, saving lives.
A study published in Annals of Oncology found that men who smoke and have multiple oral sex partners are at higher risk of developing oropharyngeal cancer. Despite the risk, the likelihood is still relatively low, making screening a challenge.
A community-based intervention called c-CARE improved cancer literacy and reduced disparate lung cancer outcomes among minority communities. The study found that participants showed increased knowledge and self-efficacy for lung cancer screening, but not perceived susceptibility.
A new study by American Cancer Society investigators finds workers at organizations with fewer than 25 employees are less likely to have been screened for three cancers. After adjusting for socioeconomic factors and insurance status, most of the difference in screening rates disappears.
A new study found that women with disabilities are less likely to participate in breast and bowel cancer screenings due to practical barriers. Women with multiple disabilities or those without access to a car were particularly affected.
Experts from United European Gastroenterology call on European governments to develop early detection techniques for digestive cancers, including faecal microbiota screening and gastric cancer screening. The aim is to improve outcomes and save thousands of European lives.
A re-analysis of USPSTF evidence suggests flexible sigmoidoscopy may reduce all-cause mortality, contrary to previous guidelines. Researchers found that looking at cohorts as separate trials, rather than aggregating them, strengthened the evidence supporting screening with flexible sigmoidoscopy.
A new report reveals a significant increase in colorectal cancer mortality rates among adults under 55, with the rise confined to white individuals. Despite declining CRC incidence rates in other age groups, the authors suggest that rising mortality may be due to true disease occurrence rather than earlier detection.
Researchers found a higher prevalence of cancer at baseline screening in individuals with Li-Fraumeni syndrome, highlighting the feasibility of a comprehensive cancer screening protocol. The study demonstrated that whole body MRI screening can detect new primary cancers in up to 7 percent of patients.
A collection of articles on hereditary cancer syndromes, including Li-Fraumeni and Lynch syndromes, has been published in JAMA Oncology. The studies focus on the effectiveness of intensive cancer surveillance programs for individuals with these rare syndromes.
Researchers at Dartmouth Health have received a five-year, $12.1 million NIH grant to study and improve the precision of lung cancer risk and screening. The team aims to enhance understanding of gene-environment interactions in lung cancer etiology and translate observations into improved screening eligibility criteria.
A study of nearly 10,000 women with BRCA1 and BRCA2 mutations found age-specific breast and ovarian cancer risks that vary by mutation location and family history. The findings indicate a need for individualized counseling incorporating both family history profiles and mutation location to inform preventive strategies.
Researchers have developed new breast cancer risk prediction models to identify patients at higher risk of developing occult cancers not visible on mammography. The clinical trial, funded by the National Institutes of Health/National Cancer Institute, aims to significantly increase cancer detection rates through MRI screenings.
A study has identified eight new genetic locations associated with an increased risk of testicular germ cell tumors. The findings, published in Nature Genetics, could help doctors understand which men are at the highest risk of developing the disease and signal them to screen those patients.
Research confirms a positive correlation between HPV vaccination and increased cervical screening rates, contradicting concerns about reduced screening due to reassurance. However, vaccine cost and provider recommendations remain significant barriers to widespread adoption in the US.
The American Association for Cancer Research has published its first set of consensus screening recommendations for children with common cancer predisposition syndromes. The guidelines provide standardized approaches to surveillance and facilitate appropriate monitoring of children affected by these conditions.
The study found a 31% higher risk for African-Americans compared to whites, even after adjusting for polyp detection rate and other factors. Blacks were more likely to receive colonoscopies from physicians with lower polyp detection rates, indicating lower quality care.
Researchers at the University of Gothenburg have developed a new method for early cancer diagnosis that uses DNA barcoding to detect tumor cells in blood. The technique has been shown to increase sensitivity by thousand-fold, making it possible to screen at-risk patient groups and spot relapsing patients more effectively.
A new study found that people with organ transplants are at higher risk of developing and dying from cancer than the general population, yet their rates of cancer screening do not meet existing guidelines. The study examined 6,392 patients who had organ transplants in Ontario between 1997 and 2010.
Black men in the US are at a higher risk of developing preclinical prostate cancer and having it progress quickly to advanced stages. Screening policies may need to be tailored to their higher-risk status.
Analyzing four initial diagnostic protocols for asymptomatic microscopic hematuria, researchers found that combining renal ultrasound and cystoscopy was the most cost-effective approach. This method reduced incremental cancer detection costs by $53,810 per case.
Researchers found a genetic variant associated with reduced HPV infection and cervical cancer risk in Saudi Arabia. This variant may be more common in populations with lower cervical cancer incidence rates.
Colorectal cancer rates in New Zealand are increasing, particularly among younger adults. The study found a significant rise in rectal cancer incidence in men and women under 50, while older adults saw an increase in proximal cancer incidence.
A study of over 3,000 childhood cancer survivors found that 12% carry germline mutations associated with increased cancer risk. Genetic screening is recommended for these patients to prevent future cancers and design personalized therapeutic approaches.
The article reviews current screening practice for melanoma in the US, highlighting risk groups and proposing full screening recommendations. The authors critically assess the USPSTF's 2016 Draft Recommendation Statement and propose evidence-based guidelines for screenings.
A free lung cancer screening in the Augusta area found more than double the cancer rate of previous screenings, with 3% of participants diagnosed with lung cancer. The majority of cases were caught early, with a 90% overall survival rate for those detected before symptoms appeared.
Researchers found that cytology was very sensitive and consistent for detecting invasive cervical cancer even in low-resource settings. Cytology may be used to diagnose cervical cancer earlier in women at high risk, leading to improved overall survival from the disease.
A recent study found a significant increase in colorectal cancer incidence rates among young adults, including those in their early 50s. Rectal cancer rates are rising even faster, with three in ten diagnoses now in patients under 55.
Maunil Bhatt, a Boston University School of Medicine resident, received a Global Surgery Research Fellowship Award for his project on screening esophageal squamous cell cancers in rural India using the EsophaCap device. He plans to train and teach in low-income countries to address disparities in access to surgical care.