Researchers at UTMB have developed a promising drug that significantly increases muscle size, strength and metabolic state in aged mice. The study found that the drug resets muscle stem cells to a more youthful state, rejuvenating them to effectively repair muscle tissues.
A study published in JAMA Network Open reveals a slight increase in readmission rates among patients discharged from Swiss hospitals under flat-rate payment structures. The researchers found that the rate of 30-day readmissions rose from 14.4% to 15.0%, raising concerns about early discharges and potential impact on hospital quality.
Adults with moderate to severe OSA who experience excessive daytime sleepiness are at greater risk for cardiovascular diseases than those without it. They are more likely to have been diagnosed with heart failure and experience cardiovascular events.
Astronomers have discovered evidence of a gigantic remnant surrounding an exploding star, indicating that it erupts regularly on a massive scale for millions of years. The team found a super-remnant measuring almost 400 light years across, which is unusually large compared to other known nova systems.
A new study measures the effectiveness of underground passageways that let fauna cross highways safely, finding higher road mortality at fence ends. Fencing and underpasses can reduce roadkill numbers by discouraging animals from crossing busy lanes.
A study found that Chilean food regulations targeting obesity have a positive impact on mothers' understanding, perceptions, and spending habits. Mothers recognized healthier choices and perceived a cultural shift toward healthier eating.
Researchers at NIHR Guy's and St Thomas' Biomedical Research Centre develop a treatment involving patients' modified cells, restoring healthy levels of integrin α4β7, effective in treating Crohn's disease. The proposed Tribute Trial will test the treatment's safety and effectiveness.
Researchers discuss the potential of brain-computer interfaces to aid and restore communication for people with severe speech and physical impairments. The talk highlights the importance of choosing the right technology that maximizes reliability and minimizes fatigue and frustration.
The article reviews the challenges, needs, and opportunities of strawberry growers across the US, highlighting increasing use of protected culture strawberry production. Key findings also discuss pest control, labor availability, and consumer demand for year-round availability.
A new study uses cellular barcoding to pinpoint cells responsible for breast cancer's spread, shedding light on how chemotherapy works and identifying targets for new treatments. Researchers hope to develop targeted therapies by understanding the molecular basis of cancer cell behavior.
A new study found that genetic diversity is key to helping frogs survive the deadly Ranavirus disease. The research showed that a specific combination of immune genes can help tadpoles limit the severity of the virus. This finding has implications for frog species in Florida, which are threatened by the disease.
Genevera Allen, a Rice University statistician, emphasizes the need for machine learning systems to question their predictions and assess uncertainty. She argues that current ML techniques often rely on uncorroborated data-driven discoveries, leading to reproducibility issues in fields like precision medicine.
Researchers have developed a novel PET/CT tracer that detects and characterizes blood clots in the legs, where conventional imaging has limitations. The new imaging agent may provide more accurate diagnoses and information on clot growth or embolization, leading to changes in clinical intervention.
Archaeologists found evidence of household items, tools, and ceremonies that suggest Native communities in Marin County persisted outside of missions. These findings challenge the dominant narrative of cultural extinction and highlight the resilience of Coast Miwok communities.
Researchers found that androsterone, a steroid hormone produced by the placenta, plays a crucial role in male genital development. The study also suggests that placental dysfunction can lead to disorders of male genital development.
A pooled analysis of 41 studies found that interval training reduced overall weight and percentage body fat, with a 28.5% greater reduction in weight compared to continuous moderate intensity exercise.
The researchers used electrostatic force microscopy with synchronized laser pulses to create a movie of recombination as it occurred, allowing them to spot speedy electrons and holes in motion. This new method may improve the efficiency of solar panels by reducing energy losses due to recombination.
A study by University of Birmingham researchers found lower brain connectivity in 'night owls' compared to morning larks, leading to poorer attention, slower reactions and increased sleepiness. This can be particularly problematic for those forced to fit into a societal 9-5 working day that doesn't align with their natural rhythms.
A new study suggests that coeliac disease permanently replaces 'tissue-healing' T cells with 'pro-inflammatory' T cells in the bowel, causing chronic inflammation and potentially contributing to other intestinal disorders. The research has implications for gut health in affected patients.
A recent special issue published in Risk Analysis examines how attitudes and perceptions of risk affect the acceptance of autonomous vehicles. Studies found that most people prefer defaults to staying in their lane when faced with a collision, and social trust plays a significant role in public acceptance.
The COMET Project aims to create a low-carbon special powertrain research center at TU Graz, focusing on CO2-neutral fuels, hybrid drive technology, and electric powertrain components. The four-year project is funded by six million euros and strengthens Austria's research and production location.
Scientists have discovered biologically active compounds in marine invertebrates that exhibit strong antitumor and antimicrobial properties. These compounds show potential as new treatments for cancer and can also be used to develop effective insecticides.
A simple blood test can now identify women at high risk of stillbirth due to a liver disorder, allowing targeted interventions and reducing unnecessary early deliveries. For most women with the condition, regular bile acid testing will suffice, reassuring them that their pregnancy is not at increased risk.
A study by German scientists uses AI to enhance climate and Earth system models, improving predictions for extreme events and seasonal changes. By combining physical modeling with machine learning techniques, researchers aim to create more accurate models that capture complex dynamic processes.
The study predicts three plausible future scenarios for the research ecosystem, driven by technology advancements and changing funding models. Researchers can expect benefits from faster publication, improved reproducibility, and greater career flexibility.
A new study from Ohio State University finds that women in relationships with men who regularly watch pornography are more likely to report symptoms of an eating disorder. Perceived pressure to be thin is also a significant concern, with some women feeling pressured by their partners to lose weight and have a thin body.
A Kent State University study reveals that students multitask more frequently in online courses than in traditional face-to-face courses. Students who prefer multitasking do so more often in online courses, while those who believe they can self-regulate exhibit less multitasking.
Researchers have developed a new live-imaging technique that detects short-lived leaks in epithelial tissues and reveals an active repair mechanism involving the protein Rho. This discovery could provide insights into diseases targeting the epithelial barrier, such as those caused by microbes, allergens, and cancers.
Two Clemson University bioengineers, Will Richardson and Naren Vyavahare, have received NIH grants for new research related to the heart, totaling $4.1 million. They are working on projects aimed at treating cardiac fibrosis and reversing vascular calcification, which could impact millions of patients with cardiovascular disease.
Researchers discovered a link between Escherichia coli and colorectal cancer risk through colibactin, a genotoxic warhead that damages DNA. The study identified potential biomarkers for assessing colorectal cancer risk and provides significant mechanistic insights into the carcinogenic activities of colibactin.
Researchers found that social threat learning, such as watching a video or receiving oral instructions, can influence decision-making just as strongly as first-hand experience. Participants who learned a certain image was dangerous continued to avoid it, even when it led to more shocks, indicating irrational behavior.
The report highlights the expanding role of interventional inflammatory bowel disease (IBD) endoscopy in managing complex conditions, such as strictures, fistulas, and colitis-associated neoplasia. This approach can help reduce or postpone surgical resection and treat postoperative adverse events.
Researchers discovered a rare tumor type that can't synthesize cholesterol, leading to its dependence on external nutrients. This vulnerability can be exploited with therapies blocking cholesterol uptake, offering a potential treatment for drug-resistant ALCL cells.
A recent study published in the Journal of Lipid Research found that the protein makeup of HDL particles plays a crucial role in their ability to predict heart health. The research, led by Nathalie Pamir, identified genetic variants linked to cholesterol efflux capacity and proteins associated with HDL's activity.
A recent survey by Michigan State University found that the oldest Americans are most focused on reducing food waste, with 88% of all respondents taking steps to reduce it. Among those who make efforts, 71% try not to purchase excess food and 71% often consume food before it spoils.
A study from the University of Virginia Health System suggests that an antidepressant drug could stop deadly sepsis by regulating inflammation. The researchers tested the drug in a mouse model and found it to be effective, paving the way for potential human trials.
Researchers studied how colibactin damages DNA and created a novel technique to identify DNA adducts. They isolated and characterized the products of the reaction with DNA, revealing a cyclopropane ring structure that forms the colibactin warhead.
Scientists at IST Austria found a new mechanism for lateral inhibition in zebrafish ovarian follicles, where the most rapidly growing cell inhibits its neighbors through mechanical compression. This process leads to the formation of a micropyle precursor cell critical for fertilization.
Rice University researchers have developed a method to capture 4D data using 2D microscopes, enabling scientists to visualize molecules' locations and movements in living cells. The technique uses custom phase masks to manipulate light and separate spatial and temporal information.
A decolonization protocol, including antiseptic soap, mouthwash, and nose ointment, was found to reduce MRSA infections by 30% compared to hygiene education alone. Patients who adhered to the regimen had significantly fewer MRSA infections, with a 44% reduction in those who missed no doses.
A study published in Genes & Development sheds light on the damage caused by senescence, a vital cell process that plays a key role in aging. The research reveals that manipulating tiny parts of cells can prevent certain forms of cellular damage.
A recent study published in The FASEB Journal revealed that Static Magnetic Field treatment can significantly enhance osteogenesis in human bone-derived mesenchymal stem cells. The researchers observed improved bone formation potential and better osteogenic markers in the SMF-treated cells compared to the control group.
A child with multiple siblings is more likely to be a victim of sibling bullying than those with only one sibling. Researchers found that firstborn children and older brothers tend to be the perpetrators, while female children and younger children are often targeted.
A UCLA-led team has developed a highly durable aerogel that can withstand intense heat and severe temperature changes, making it an ideal material for insulating spacecraft. The new ceramic aerogel is ultra-lightweight, flexible, and resistant to fire and corrosion.
A global study analyzing thousands of case studies found that eight out of ten total knee replacements and six out of ten total hip replacements will last 25 years. The study provides reliable data on the long-term outcomes of joint replacement surgery, giving patients and clinicians a better understanding of what to expect.
A new electronic decision support tool has shown promise in improving asthma care, with a 45% increase in patients receiving asthma action plans and a 59% increase in asthma control assessments. The system uses data from patient questionnaires to provide personalized recommendations for clinicians.
Researchers used small satellites to observe changes in 85,000 North American lakes over summer 2017, finding significant shoreline fluctuations that add up to hundreds of square kilometers. These findings could impact calculations of natural greenhouse gas emissions from these northern lakes.
Researchers found that caring contacts reduced suicidal ideation and risk by lowering odds from 15% to 9%. Simple text messages can provide support during stress and transition, improving mental health outcomes.
Researchers at St. Jude Children's Research Hospital have identified genetic variations in ERG associated with an increased risk of acute lymphoblastic leukemia in Hispanic children. These variations were more common and had a stronger effect in Hispanic children than in other ethnic groups.
A simulation training study found that blindfolding pediatric team leaders improved their leadership skills ratings by 11% compared to non-blindfolded leaders. The technique may help save lives by enhancing communication and reducing distractions during resuscitation scenarios.
A new method called FIt-SNE has been developed to speed up the analysis of single-cell gene expression data, reducing rendering time from over three hours to just fifteen minutes. This innovation allows researchers to capture rare cell populations and visualize thousands of genes at the level of single cells simultaneously.
New research from the European Society of Cardiology shows that physiological health, as measured by exercise stress testing performance, is a better predictor of survival than chronological age. This finding suggests that individuals who are physically fit may live longer than those who are not.
A collection of 27 papers has been compiled to better understand the pathophysiology of endocrinopathic laminitis in horses. The research highlights the key role of insulin dysregulation and equine metabolic syndrome in driving the condition.
A team of ETH Zurich researchers used single-molecule force spectroscopy to investigate how membrane proteins become embedded in cell membranes. They discovered the role of two helper proteins, insertase and translocase, which enable membrane proteins to embed themselves in the membrane. The study sheds light on the folding pathways of...
A new study published in The Lancet found that one brief exposure to general anesthesia does not result in measurable neurodevelopmental or behavioral problems up to the age of 5 years. However, more research is needed to confirm the findings in girls and children with multiple and prolonged exposure to anesthesia.
A new study by UCSF researchers found that the majority of triggers for atrial fibrillation (AF), an irregular heartbeat, are easily modifiable lifestyle choices. Nearly 74% of patients reported experiencing AF triggered by common factors such as alcohol, caffeine, exercise, and lack of sleep.
Tropical Cyclone Gelena is being weakened by strong northerly wind shear. The satellite imagery shows clouds pushed south of the center, reducing the storm's power.
A new study suggests that a program providing bridge care between hospital and home can reduce readmissions and deaths after a heart attack. The Heart Care Navigation Team's program assigns a health advocate and nurse navigator to help patients with timely access to follow-up care.
A precise definition of a black hole's singularity proves elusive, with diverse definitions among physicists and different physical approaches to understanding the phenomenon.
Measurements of gravitational waves from binary neutron stars will definitively resolve the debate on the universe's expansion rate. By observing 50 binary neutron stars over the next decade, scientists can calculate the Hubble constant accurately, resolving the conflict between conflicting measurements.