Articles tagged with Cancer Screening
A new report reveals a significant increase in colorectal cancer mortality rates among adults under 55, with the rise confined to white individuals. Despite declining CRC incidence rates in other age groups, the authors suggest that rising mortality may be due to true disease occurrence rather than earlier detection.
Researchers found a higher prevalence of cancer at baseline screening in individuals with Li-Fraumeni syndrome, highlighting the feasibility of a comprehensive cancer screening protocol. The study demonstrated that whole body MRI screening can detect new primary cancers in up to 7 percent of patients.
A collection of articles on hereditary cancer syndromes, including Li-Fraumeni and Lynch syndromes, has been published in JAMA Oncology. The studies focus on the effectiveness of intensive cancer surveillance programs for individuals with these rare syndromes.
Researchers at Dartmouth Health have received a five-year, $12.1 million NIH grant to study and improve the precision of lung cancer risk and screening. The team aims to enhance understanding of gene-environment interactions in lung cancer etiology and translate observations into improved screening eligibility criteria.
A study of nearly 10,000 women with BRCA1 and BRCA2 mutations found age-specific breast and ovarian cancer risks that vary by mutation location and family history. The findings indicate a need for individualized counseling incorporating both family history profiles and mutation location to inform preventive strategies.
Researchers have developed new breast cancer risk prediction models to identify patients at higher risk of developing occult cancers not visible on mammography. The clinical trial, funded by the National Institutes of Health/National Cancer Institute, aims to significantly increase cancer detection rates through MRI screenings.
A study has identified eight new genetic locations associated with an increased risk of testicular germ cell tumors. The findings, published in Nature Genetics, could help doctors understand which men are at the highest risk of developing the disease and signal them to screen those patients.
Research confirms a positive correlation between HPV vaccination and increased cervical screening rates, contradicting concerns about reduced screening due to reassurance. However, vaccine cost and provider recommendations remain significant barriers to widespread adoption in the US.
The American Association for Cancer Research has published its first set of consensus screening recommendations for children with common cancer predisposition syndromes. The guidelines provide standardized approaches to surveillance and facilitate appropriate monitoring of children affected by these conditions.
The study found a 31% higher risk for African-Americans compared to whites, even after adjusting for polyp detection rate and other factors. Blacks were more likely to receive colonoscopies from physicians with lower polyp detection rates, indicating lower quality care.
Researchers at the University of Gothenburg have developed a new method for early cancer diagnosis that uses DNA barcoding to detect tumor cells in blood. The technique has been shown to increase sensitivity by thousand-fold, making it possible to screen at-risk patient groups and spot relapsing patients more effectively.
A new study found that people with organ transplants are at higher risk of developing and dying from cancer than the general population, yet their rates of cancer screening do not meet existing guidelines. The study examined 6,392 patients who had organ transplants in Ontario between 1997 and 2010.
Black men in the US are at a higher risk of developing preclinical prostate cancer and having it progress quickly to advanced stages. Screening policies may need to be tailored to their higher-risk status.
Analyzing four initial diagnostic protocols for asymptomatic microscopic hematuria, researchers found that combining renal ultrasound and cystoscopy was the most cost-effective approach. This method reduced incremental cancer detection costs by $53,810 per case.
Researchers found a genetic variant associated with reduced HPV infection and cervical cancer risk in Saudi Arabia. This variant may be more common in populations with lower cervical cancer incidence rates.
Colorectal cancer rates in New Zealand are increasing, particularly among younger adults. The study found a significant rise in rectal cancer incidence in men and women under 50, while older adults saw an increase in proximal cancer incidence.
A study of over 3,000 childhood cancer survivors found that 12% carry germline mutations associated with increased cancer risk. Genetic screening is recommended for these patients to prevent future cancers and design personalized therapeutic approaches.
The article reviews current screening practice for melanoma in the US, highlighting risk groups and proposing full screening recommendations. The authors critically assess the USPSTF's 2016 Draft Recommendation Statement and propose evidence-based guidelines for screenings.
A free lung cancer screening in the Augusta area found more than double the cancer rate of previous screenings, with 3% of participants diagnosed with lung cancer. The majority of cases were caught early, with a 90% overall survival rate for those detected before symptoms appeared.
Researchers found that cytology was very sensitive and consistent for detecting invasive cervical cancer even in low-resource settings. Cytology may be used to diagnose cervical cancer earlier in women at high risk, leading to improved overall survival from the disease.
A recent study found a significant increase in colorectal cancer incidence rates among young adults, including those in their early 50s. Rectal cancer rates are rising even faster, with three in ten diagnoses now in patients under 55.
Maunil Bhatt, a Boston University School of Medicine resident, received a Global Surgery Research Fellowship Award for his project on screening esophageal squamous cell cancers in rural India using the EsophaCap device. He plans to train and teach in low-income countries to address disparities in access to surgical care.
A one-off bowel screening test can prevent more than half of potential bowel cancers from developing and reduce deaths by two-thirds. The test is effective in reducing cancer deaths for at least 17 years, according to a study published in The Lancet.
A new study from Germany found that MRI screening improved early diagnosis of breast cancer in women with an average risk of developing the disease. The study detected 60 additional cancers, including 40 invasive cancers, for an overall supplemental cancer detection rate of 15.5 per 1,000 women.
Early cancer diagnosis doesn't always result in longer life, as screenings come with built-in risks like false positives and missed diagnoses. Research suggests that frequent screening may not extend quality of life, but rather just delays the inevitable. The study's findings challenge the conventional notion that early detection is al...
A Danish cohort study found that breast cancer screening was not associated with a reduction in advanced tumors, but rather an increase in nonadvanced tumors and ductal carcinoma in situ (DCIS). The study estimates that approximately 1 in 3 invasive tumors diagnosed in screened women represent overdiagnosis.
A new study found that the Affordable Care Act (ACA) increased mammography use among all economic subgroups, including those with lower incomes. However, colonoscopy screening rates remained unchanged despite eliminating out-of-pocket expenses under the ACA. The findings suggest that other barriers to colonoscopy access may still exist.
A new study reveals that women with advanced kidney disease are at a higher risk of developing cancer, highlighting the importance of targeted screening strategies.
A special issue of Cancer Epidemiology shows that cancer registries in Kenya, Uganda, Colombia, India, and Barbados can provide valuable data for policy-making on cancer prevention, early detection, and treatment. The low cost of registration per person and economies of scale make them a viable option for resource-constrained countries.
A special issue of Cancer Epidemiology highlights the importance of cancer registration in resource-constrained settings, demonstrating cost savings through economies of scale. The study reviews cancer registries in Kenya, Uganda, Colombia, India, and Barbados, offering lessons for other countries with similar constraints.
A large-scale prospective study has generated new insights into patient perceptions and experiences with direct-to-consumer genetic testing. Despite modest cancer risks, most customers did not change their diet, exercise, or screening habits. However, men who received elevated prostate cancer risk estimates changed their supplement use...
A 15-year study of prostate cancer patients found little difference in mortality between those screened annually and those not screened. However, the data suggest that personalized screening strategies could identify men at higher risk of death from other diseases.
A new series published in The Lancet highlights the need for international efforts to end preventable deaths from breast and cervical cancer, particularly in low- and middle-income countries. Cost-effective interventions, such as routine HPV vaccination and cervical screening, can significantly reduce mortality rates if implemented.
A new study from Harvard T.H. Chan School of Public Health suggests that less-intensive cervical cancer screening is needed among women who have been vaccinated against human papillomavirus (HPV), as these women face a substantially lower risk of developing cervical cancer.
The study found improvements in some quality measures, such as recommended medical treatment and cancer screening, but worsened in others, like antibiotic use. Patient experience ratings also showed significant gains. However, deficits in care continue to pose serious health risks.
A new study reveals low rates of pregnancy screening among adolescent females with acute leukemia before receiving chemotherapy that can cause birth defects. The analysis found that adolescents with ALL had the lowest rates of pregnancy testing, and there was substantial variation in screening patterns across hospitals.
A study by Dr. Aisha Lofters and her team found that Muslim women were more likely to be up-to-date on breast cancer screening, despite living in low-income neighborhoods. This suggests that religious beliefs may play a role in health behaviors like cancer screening.
Studies suggest that population commitment, physician implication, and reassurance in screening can improve participation rates. A patient-centred approach in Australia improved screening participation by offering a combined cancer screening service. Additionally, nurse-led clinics can provide effective early diagnosis and prevention o...
A new report from UC Davis Institute for Population Health Improvement highlights areas where increased cancer screening and control efforts can save lives. Effective screening tests exist for several cancers, yet many Californians remain under-screened, leading to late-stage diagnoses and reduced treatment success.
A new study found that cancer screening guidelines for organ transplant recipients are inconsistent, varying in recommendations for skin and other types of cancer. Researchers highlight the need for more studies to inform guidelines involving transplant patients, oncologists, and cancer specialists.
A recent study by the University of California - Davis Health found that Hispanic men in California have lower rates of screening for colorectal cancer compared to white men. The study suggests that increased screening can help reduce the incidence and mortality rates of the disease among this population.
A team of researchers from the University of Sheffield has identified 788 biomarkers in blood that could be used to develop an early stage cancer screening test. The comprehensive list of relevant cancer blood biomarkers has been compiled through a systematic review of 4,000 studies published over the last five years.
A study of childhood cancer survivors found that most had no reported psychological symptoms, but those who did often experienced multiple symptoms and distinct profiles. The researchers emphasize the need for robust screening efforts and identification of appropriate treatments to help prevent behavioral, emotional, and social problems.
A study involving UT Southwestern researchers found that primary care visits lead to higher rates of colon cancer screening and better follow-up care, even in health systems promoting mail-in stool blood tests. This result underscores the importance of primary care physician visits in a virtual care era.
A clinical trial found that patient navigators increased the likelihood of low-income and ethnic minority patients receiving cancer screenings. The study showed that 32% of patients connected with navigators completed at least one overdue screening, compared to 18% in the control group.
A recent survey found that less than half of family physicians believe that lung cancer screening using low-dose computed tomography (LDCT) reduces lung cancer-related deaths. Despite the American Cancer Society's support for LDCT screening, many physicians are unsure about current recommendations.
Researchers are developing imaging biomarkers and optical imaging tools to screen for ovarian cancer, a 'silent killer' of women. The goal is to enable early detection and save lives.
A study of nearly 35,000 women found that those developing new-onset atrial fibrillation had an increased risk of cancer over a 20-year period. The risk was highest for colon cancer and persisted even after adjusting for other factors.
Researchers found a significant increase in colorectal cancer cases under 50 years old, with advanced stages at diagnosis. The study suggests healthcare providers need to be more vigilant in detecting symptoms in younger patients.
A study published in JAMA found that longer periods of film readers interpreting screening mammograms did not result in a reduced rate of breast cancer detection. The researchers investigated the impact of changing the order in which two experts examined digital mammograms on cancer detection rates, but found no significant difference.
A study by Nancy R. Kressin and colleagues found that dense breast notifications sent to women after mammography contain poor readability and understandability, potentially exacerbating disparities in breast cancer screening. Only three states' notifications met the recommended readability level of grades 7-8 or above.
A study published in JAMA found that adding tomosynthesis to digital mammography significantly increased cancer detection rates and reduced recall rates for women with dense breasts. The findings suggest that supplemental breast cancer screening using tomosynthesis may improve outcomes for women with varying levels of breast density.
A recent U.S. Preventive Services Task Force recommendation suggests pairing smoking cessation with lung cancer screening to maximize benefits and reduce risk. This guideline aims to provide tobacco treatment in conjunction with lung screening to encourage smokers to quit.
Researchers found that high-risk lung cancer patients who are cleared of disease in their initial test do not need annual low-dose computed tomography (LDCT) screenings. The study suggests that reducing the frequency of screening could save millions in healthcare costs and spare patients from radiation exposure and false positive results.
A Cancer Research UK study found that ethnic minority women in the UK are more likely to believe cancer is incurable and down to fate, which may explain lower attendance at cancer screenings. The study also found that fear of cancer and language barriers can affect attitudes towards cancer.
A new study finds that most cancer screening guidelines do not adequately explain the risks and benefits of recommended actions, leading to unclear tradeoffs. Guidelines are often presented in a way that gives a false picture of the benefits and harms.
A recent study has found that most US cancer prevention guidelines do not provide sufficient information on benefits and harms, making it difficult for clinicians and patients to make informed decisions. The researchers analyzed data from various guidelines and found that 39% of recommendations were given comparable ratings, while 14.5...
A study published in JAMA Oncology found that 3D mammography improved cancer detection and reduced call backs over three years. Regularly scheduled 3D mammography imaging maintained these benefits, even after a patient's first screening.
A new study found significant reductions in breast cancer screening outcomes after implementing digital breast tomosynthesis (DBT), including lower patient recall rates and a decline in interval cancers. The study suggests DBT can be sustained over time with improved outcomes.
The report highlights the need for increased data collection and research on cancer risk, incidence, and prevalence in LGBT communities. It recommends collecting sexual orientation and gender identity (SOGI) information to support targeted cancer prevention and treatment strategies.