Articles tagged with Cancer Screening
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A new study suggests that US cervical cancer incidence rates may be underestimated due to the inclusion of women who have undergone a hysterectomy in calculations. Rates were found to increase with age, particularly among older women and black women.
A review of 47 studies involving over 15,000 patients found that liver cancer screening using ultrasound scans and blood tests significantly improved three-year survival rates for people with cirrhosis. Cirrhosis patients who received screening were more likely to receive curative treatment rather than palliative care.
Recent guidelines on cervical cancer screening have left clinicians and patients with a question about the best approach. Experts recommend considering individual patient values and preferences when choosing between Pap testing alone and cotesting with HPV testing.
A large study of over 224,000 patients and 314,000 colonoscopies found that higher adenoma detection rates are associated with a decreased subsequent risk of colorectal cancer. The study confirms that adenoma detection rates are an accurate quality metric for clinicians performing colonoscopies.
Research from The Netherlands found that extending national breast cancer screening programs to women aged 70 and over does not decrease advanced stage cancer detection, but rather increases early-stage tumors. This leads to a large proportion of women being over-treated and at risk from the harmful effects of treatment.
A UK study found that approximately one third of women are at higher risk of developing breast cancer and may require more frequent mammograms. Women with dense breast tissue were 2.9-fold more likely to develop breast cancer, highlighting the importance of personalized screening frequency.
A new multi-target stool DNA test detects 92.3% of colon cancers, outperforming the current standard fecal immunochemical test. The test identified advanced precancerous polyps nearly 70% of the time compared to 45% for the existing method.
A recent study found that colon cancer incidence rates have dropped by 30 percent in the US among adults 50 and older due to widespread colonoscopy adoption. Colonoscopy use has almost tripled among adults ages 50-75, leading to significant declines in mortality rates as well.
The University of Texas Medical Branch (UTMB) has received $3.2 million from the Cancer Prevention and Research Institute of Texas (CPRIT) to continue its collaborative cancer research program in Texas. CERCIT researchers are studying cancer treatment outcomes, access to care, and patient survival rates.
A new study from Aarhus University suggests that screening for breast cancer primarily detects indolent cancer cases, which would otherwise have been fatal. Despite detecting more early-stage cases, the number of advanced stages has remained virtually unchanged.
Secondary thyroid cancer is more deadly for young individuals compared to primary thyroid cancer. This study highlights the importance of screening young cancer survivors to detect potentially life-threatening tumors.
A new study found that 3D mapping biopsies detect nearly three times as many cancerous zones in prostate cancer patients compared to ultrasound-guided biopsies. The study suggests that 3D mapping biopsies can accurately assess the location, stage, and risk of prostate cancer, leading to more targeted treatment options.
A new photon-counting technique improves cancer detection rates in digital mammography screening, particularly for ductal carcinoma in situ. The method reduces scattered radiation and noise, enabling lower doses and improved outcomes.
A study by Loyola University Medical Center researchers could lead to the development of a 'liquid biopsy' test for bladder cancer using microscopic droplets shed by cancer cells in urine. This non-invasive test would require only a simple urine sample, potentially informing treatment decisions.
A new analysis reveals steady progress against cancer's burden, despite underestimation due to other disease advancements. Researchers measured years of life lost to cancer and found increased longevity offsetting progress.
A new nomogram developed by Roman Gulati et al. estimates the likelihood of overdiagnosis for screen-detected prostate cancers, considering patient age, Gleason score, and PSA level at diagnosis. The model predicts risks ranging from 2.9% to 88.1% depending on individual characteristics.
Lynch syndrome increases the risk of colon and endometrial cancers. Screening all endometrial cancers for this genetic mutation can lead to early detection and improved patient outcomes for women at high risk.
A new study by SDSU researchers found that celebrity cancer diagnoses lead to a substantial rise in quitting smoking queries, even after media coverage subsides. The study analyzed Google News archives and public search activity surrounding former Brazilian President Lula da Silva's diagnosis, revealing a lasting impact on behavior.
New data from the NLST suggests that low-dose CT screening for lung cancer may overdiagnose up to 22% of non-small cell lung cancers. However, the rate is significantly lower than projected for other cancer screenings, supporting the implementation of lung cancer screening programs.
A computer model found that genetic screening for breast cancer risk in conjunction with MRI can reduce cancer deaths and identify a population at an intermediate risk. The study compared two tests to categorize patients by lifetime risk, finding the 7SNP test was most cost-effective for those with an intermediate risk.
The US Preventive Services Task Force found no evidence that screening for oral cancer by primary care physicians reduces morbidity or mortality. Oral cancer is often diagnosed at advanced stages, highlighting the importance of earlier diagnosis.
A new study published in Annals of Internal Medicine suggests that calculating comorbidity-adjusted life expectancy may help physicians determine whether to continue or stop cancer screening in elderly patients. The researchers found that patients with higher levels of comorbidity had shorter life expectancies than healthy patients of ...
A study of four European trials found that HPV-based screening provided greater protection against invasive cervical cancer than cytological screening. The analysis showed that HPV-based screening protected 60-70% more women from invasive cancers, with increased protection seen in women aged 30-35 years and those screened every 5 years.
A study by University of Manchester scientists found that less than 7% of cervical cancer patients in Kenya receive optimal treatment, leading to high mortality rates. The researchers are now seeking funding to implement simple changes in hospital procedures to improve cancer treatment in the country.
The Cell-CT platform detected lung cancer in patient sputum samples with a sensitivity of over 95% and specificity of 99.8%. The technology creates comprehensive 3D digital images of cells, making it possible to determine the presence or absence of cancer with great accuracy.
Research reveals South Asian-Canadians in Peel have a 15% lower rate of cancer screening, making them more vulnerable to cancer deaths. The study attributes this disparity to barriers such as long wait times and limited education on cancer risk factors.
Researchers at the University of Twente in the Netherlands have developed a new imaging tool called the photoacoustic mammoscope, which uses a combination of infrared light and ultrasound to create a 3-D map of the breast. The device has shown promise in detecting breast cancer early, when it is most treatable.
A survey of 317 U.S. men and women aged 50-69 found that most patients are not being told about the possibility of overdiagnosis and overtreatment due to cancer screenings. Nearly 59% would continue screening despite learning it results in 10 overtreated individuals per life saved from cancer death.
A study from University of Texas Medical Branch found that more than 40% of men over 75 undergo PSA screening, despite no medical organization recommending it for this age group. The researchers suggest that decision-making by primary care physicians is a major reason for the continued high PSA rate.
A study by Yale researchers found that Medicare spent $447 million annually on PSA-based screenings for prostate cancer, with most of it going to men over 75. The cost variation was mainly due to follow-up tests, not the use of the PSA itself.
A new study by NYU Steinhardt researcher Niyati Parekh suggests that disturbances in body insulin and glucose levels are associated with an increased risk of obesity-related cancers. The research, which analyzed data from the Framingham Heart Study, recommends lifestyle changes to alleviate these disturbances as a cancer control tool.
A new analysis reveals that regular mammograms before age 50 significantly reduce breast cancer deaths in younger women. The study analyzed data from invasive breast cancers diagnosed between 1990 and 1999, finding that only 13% of cases occurred in women aged 70 or older.
A new clinical risk calculator software has been developed to accurately classify benign and malignant spots on lung scans of smokers. The software uses a prediction model that considers several factors, including size, age, family history, and location of the nodule, to predict the probability of cancer.
A new screening strategy for ovarian cancer has shown high specificity in detecting the disease before it becomes lethal. The two-stage approach incorporates changes in a blood protein called CA125 and has been found to have a positive predictive value of 40% for invasive ovarian cancer.
A 12-year study found CA-125 to have a 99.9% specificity in detecting high-grade invasive ovarian cancers at curable stages, while the test failed to detect two borderline cases. The study's results suggest CA-125 as a promising first step in early disease detection.
Researchers develop a new microfluidic chip that can capture over 90% of circulating tumor cells from patient blood, providing potential applications for cancer screenings, treatment assessments, and disease progression determination. The technique shortens processing time and improves efficiency compared to existing methods.
A new study published in Radiology found that digital tomosynthesis reduces the recall rate in breast cancer screening, particularly in younger women and those with dense breast tissue. The addition of tomosynthesis resulted in a 30 percent reduction in overall recall rate, compared to conventional mammography alone.
A scientific panel recommends personalized strategies to reduce cancer overtreatment by classifying indolent tumors and improving screening strategies. The goal is to detect consequential cancer while avoiding inconsequential disease.
A study found that many family caregivers of older adults with dementia are willing to consider stopping cancer screening, which can reduce patient burden, healthcare costs, and family caregiver distress. Caregivers are most open to discussions when focusing on quality of life and burdens and benefits for the person with dementia.
A new study suggests that STD clinics can provide essential access to cervical cancer screenings for underscreened women. The majority of women participating in the study were eager to receive the screening, and most reported not having had a pap smear in at least three years.
A recent study found that many obstetrician-gynecologists continue to provide annual cervical-cancer screenings despite updated guidelines. The research suggests less frequent screening every three years can retain most benefits while reducing harms and costs. Experts recommend a more balanced approach to cervical cancer screening.
Researchers from the University of Liverpool and University of the West of England have developed a device that can detect bladder cancer through urine scent analysis. The ODOREADER device analyzes chemicals in gas emitted from urine to produce a 'profile' that can be used to diagnose cancer cells in the bladder.
Researchers at H. Lee Moffitt Cancer Center have developed a new method to rapidly identify genetic changes in small protein fragments unique to melanoma cancer cells. The approach harnesses tumor-infiltrating lymphocytes, which have been shown to reduce cancerous lesions and improve outcomes.
A new study found that virtual colonoscopy screenings can be safely delayed for women by 5-10 years compared to men, with minimal impact on cancer detection rates. The findings suggest that women under 55 may only need to undergo screening every 10 years, while those over 60 can wait up to 5 years longer.
Researchers found that 30% of people with colorectal cancer did not act on genetic screening results, missing the diagnosis of Lynch syndrome. This study assesses the impact of routine screening for Lynch syndrome and highlights the importance of individuals taking action on test results.
A novel transcriptome-based classification of colon cancer has been developed, improving disease stratification based on clinicopathological variables and common DNA markers. The analysis identified six molecular subtypes associated with distinct clinical and pathological characteristics.
A study of veterans at high risk for developing lung cancer shows that low-dose computed tomography (LDCT) can effectively spot tiny lung nodules indicating the earliest stages of disease. LDCT uses less than a quarter of the radiation of a conventional CT scan, resulting in a higher detection rate compared to chest x-rays.
A new study suggests that digital direct radiography (DR) is significantly more effective than computed radiography (CR) in detecting breast cancer. DR detected 4.9 cancers per 1,000 mammograms, while CR's detection rate was 21% lower, with 3.4 cancers per 1,000 mammograms.
A new analysis found a significant link between Agent Orange exposure and high-grade prostate cancer among US Veterans. Exposure to the herbicide was associated with a 52% increase in overall risk of prostate cancer detection by biopsy, as well as a 75% increase in risk of high-grade prostate cancer.
A University of Michigan study found that despite strong recommendations to use decision aids, there is a lack of evidence on whether they work effectively. The researchers reviewed 73 decision aids for breast, cervical, colon, and prostate cancers but only half were evaluated for subsequent screening behavior.
A study from Yale University found that two views are better than one in 3D breast screening to ensure optimal cancer detection. The CC view achieves better compression and shows lesions clearer due to its ability to compress the breast tissue.
A new study reveals that breast ultrasound screening after mammography can detect an additional 3.4 cancers per thousand women screened in those with greater than 50% breast density. The detection rate is comparable to that of screening mammography for women with less dense breasts.
A Moffitt Cancer Center study found that minority groups, including blacks, Asians, and Hispanics, hold differing beliefs about cancer prevention and feel they are less likely to get cancer. The researchers concluded that more culturally relevant information is needed to reach these populations.
A new study suggests that nearly half of all deaths from prostate cancer can be predicted before age 50, based on PSA levels. Focusing testing on men at highest risk may improve the benefits and harms of screening.
The American Cancer Society's report emphasizes the importance of reducing tobacco use, improving nutrition and physical activity, and expanding cancer screening tests. The report notes significant declines in cigarette smoking prevalence but highlights concerns about heavy smoking, indoor tanning, and HPV vaccination coverage.
A Penn Medicine study found that computed tomography colonography (CTC) was used appropriately in asymptomatic Medicare patients. The study suggests that CTC may have expanded colorectal cancer screening beyond the population screened with standard optical colonoscopy.
A new study has identified genetic alterations in the RGS pathway as key factors linked to bladder cancer risk, recurrence, disease progression, and patient survival. The research found that specific variants were associated with increased or decreased risks, providing potential molecular markers for screening and treatment.
A study by Regenstrief Institute and Indiana University Center for Aging Research found that many older adults resist stopping cancer screenings, even when they may not be beneficial. The researchers suggest developing specific messages for older adults to address concerns about screening and trust in physicians.
A new study confirms the effectiveness of colonoscopy in preventing advanced colorectal cancer diagnoses, particularly for tumors on the right side of the colon. The study found a 70 percent reduction in risk for average-risk adults, supporting current medical recommendations.
Researchers used electronic health records to identify patients overdue for colon cancer screening and encouraged them to be screened. The centralized approach doubled on-time screening rates and saved health costs over two years.