A review of randomised trials on cancer screening finds that mammographic screening may not reduce breast cancer mortality as expected. The study suggests that the benefits of mammography screening are likely to have been overestimated due to an unconventional statistical method used in earlier trials.
A study found that increased screening mammography was associated with more diagnoses of small breast cancers, but not significant changes in mortality or larger cancer incidence, suggesting overdiagnosis
Researchers at MD Anderson Cancer Center have identified a potential non-invasive diagnostic tool for early pancreatic cancer detection. Glypican-1-enriched circulating exosomes were found to be present in small amounts of serum from patients with pancreatic cancer, showing high specificity and sensitivity. Early detection of pancreati...
A new study published in Radiology found that annual low-dose computed tomography (CT) screening can safely monitor people with nonsolid lung nodules, reducing the need for unnecessary surgery and additional imaging. Nonsolid nodules are visible on CT scans of the chest and management is challenging.
A new study found annual low-dose CT screening to be safe and effective for identifying pre-cancerous lung nodules. The study identified cases of cancer in participants with nonsolid lung nodules, which can progress to invasive cancer.
A large clinical trial led by The Ottawa Hospital and the University of Ottawa found that CT scans do not improve cancer detection in people with unexplained blood clots. Approximately four percent of patients from each group were diagnosed with cancer within the next year, with no difference in cancer-associated deaths.
The Harvard Medical School Cancer Biology and Therapeutics Training Program will provide specialized education and training in cancer research and treatment. The one-year, nonclinical blended-learning certificate program is designed to promote a deeper understanding of cancer biology, diagnosis, and personalized treatments.
A national survey found that only one in ten Australians report being told about the risk of overdiagnosis by their doctors, while over 90% believe people should be informed. Overdiagnosis occurs when someone is diagnosed with a disease that will never cause harm due to unnecessary labelling and treatment.
The American College of Physicians recommends screening for five common cancers: breast, colorectal, ovarian, prostate, and cervical. High-intensity screening may do more harm than good due to over-diagnosis and overtreatment. ACP advises focusing on tests that improve health and avoid harms.
A study published in Annals of Internal Medicine suggests that women with extremely dense breasts do not necessarily need additional imaging after a normal mammogram. However, those with high-risk dense breasts should discuss supplemental screening strategies with their doctors. The American College of Physicians advises 'smarter' canc...
Researchers at University Hospitals Cleveland Medical Center found a new non-invasive stool DNA testing method comparable to colonoscopy for detecting large polyps in African Americans. The study suggests this technology may improve colon cancer screening rates and decrease mortality.
A five-month media campaign in Florida's poorest counties increased black men's awareness of mouth and throat cancer, leading to a 13% rise in first-time screenings. The campaign, designed by UF Health researchers, aimed to reverse the health inequity faced by black men, who have lower survival rates due to delayed diagnosis.
A recent study found that women in states without Medicaid expansion are less likely to receive breast and cervical cancer screenings compared to those in expanding states. The disparity is significant, with uninsured women facing a 7.9% lower rate of mammograms and a 4.9% lower rate of Pap tests.
Digital breast tomosynthesis (DBT) increases cancer detection rates among women with dense breasts, with a significant improvement seen in those with dense breasts called back for mass and asymmetry. The study found a striking increase in detection among these groups, offering new insights into DBT's effectiveness.
Researchers have identified methylated DNA markers in blood samples with 80% accuracy, enabling potential non-invasive screening for cancer. The discovery could lead to earlier diagnosis and improved patient outcomes for rare cancers like pancreatic cancer.
Most breast and general surgeons still advocate for annual mammography starting at age 40, despite a 2009 USPSTF recommendation to screen biennially from 50 to 74. Researchers found 88% of breast surgeons and 82% of general surgeons recommend annual screenings.
A magnetic resonance imaging (MRI)-based screening program identified pancreatic lesions in 40% of high-risk patients, with 5 requiring surgery. The study suggests that MRI can detect cancer or premalignant lesions with good accuracy, reducing costs and increasing availability compared to more aggressive methods.
A new test developed by University of Central Florida scientist Qun Huo uses gold nanoparticles to detect cancer biomarkers, providing more accurate and earlier detection of prostate cancer. The test is cost-effective and has shown promising results in pilot studies, outperforming the current PSA screen.
The American Cancer Society's new report highlights disparities in cancer prevention and early detection efforts, including underutilized screening for colorectal and cervical cancers. Meanwhile, tobacco use remains a major cause of preventable disease and premature death, with wide variation by education and race/ethnicity.
The Global Cancer Project Map is an online resource connecting the global cancer community, enabling access to cancer projects and expertise. The map covers a range of projects, from prevention to palliative care, and aims to reduce health disparities and strengthen human capital in underserved areas.
A new study estimates that increasing screening rates to 80% in the US by 2018 would prevent 21,000 colorectal cancer deaths annually by 2030. The initiative aims to boost screening from 58% in 2013 to 80% in 2018.
A UK survey found that people's willingness to accept overdetection in cancer screening varies greatly, depending on the level of benefit and perceived harms. The study revealed that up to 14% would accept overdetection in the entire population, with median acceptability ranging from 113 to 150 cases.
Research highlights psychology's contributions to cancer risk reduction, treatment adherence, quality of life, and survivorship. Psychological science helps individuals modify unhealthy behaviors that can lead to disease, and enhances the lives of people who have survived or are living with cancer.
Research reveals that adults in Ontario with IDD are nearly twice as likely not to be up-to-date on colorectal tests compared to their non-IDD counterparts. The study highlights the need for targeted interventions to make cancer screening more equitable in this population, where chronic conditions like cancer increase with age.
Experts suggest that targeted screening programs for middle-aged and older patients using newer diagnostic tools could significantly reduce melanoma mortality rates. Studies in Australia and Germany have shown a substantial decrease in melanoma-related deaths after implementing comprehensive skin cancer screening programs.
Research presented at the American Stroke Association's International Stroke Conference 2015 found that stroke survivors have a higher annual rate of age-adjusted cancer incidence compared to the general population. Additionally, stroke survivors who develop cancer are more than three times likely to die compared to those without cancer.
A Cancer Research UK study found that nine in 10 people think cancer screening is 'almost always a good idea', despite low uptake. The researchers highlight the need for clearer information on risks and benefits to encourage informed decision-making.
A recent retrospective study found that Lung-RADS guidelines generated fewer false-positives than the National Lung Screening Trial, reducing unnecessary follow-up testing. The guidelines provide structured reporting tools for practices to benchmark performance and improve lung cancer screening's cost-effectiveness.
Researchers used the mortality-to-incidence ratio to identify global disparities in colorectal cancer screening and treatment. Countries with lower-than-expected ratios have strong national health systems with formal screening programs.
A Cancer Research UK study found that nearly 40% of people with abnormal test results ignore their next screening invitation, while just 13% of those with normal results do the same. The study highlights a small but high-risk group failing to continue with bowel cancer screening tests.
A study by Cancer Research UK found that individuals with low numeracy skills are more likely to feel negative about bowel cancer screening, including fearing abnormal results. They also tend to think the test is disgusting or embarrassing.
A recent UTMB study found that Hispanic women in the US were significantly less likely to survive endometrial uterine cancer compared to non-Hispanic white women. The study analyzed data from 69,764 women diagnosed between 2000 and 2010 and found that minority patients tend to be diagnosed with more aggressive cancer.
A new study by University of Michigan researchers suggests that using war metaphors to describe cancer can have a negative impact on prevention behaviors. Participants who were exposed to such language were less likely to consider limiting unhealthy habits like smoking and excessive alcohol consumption.
A new study suggests that supplementing breast cancer screening for women with dense breasts may not be the most effective approach. Instead, it could lead to an increase in unnecessary biopsies, highlighting the need for alternative methods to screen these high-risk individuals.
A new technique has uncovered large sets of previously unknown pancreatic cancer genes by introducing DNA transposons into mouse genomes. The study found that the Foxp1 gene drives cancer progression and is highly expressed in human cancers that have metastasised.
A new study found that digital breast tomosynthesis significantly increases cancer detection in women with dense breasts. In a population-based mammography screening program, tomosynthesis improved cancer detection rates by 30-40%, particularly for invasive cancers and those with fatty breasts.
A new lung cancer risk model, PLCOm2012, refines decisions to screen individuals for annual CT scans, identifying a risk threshold for selecting high-risk smokers. The study found that this threshold resulted in higher sensitivity and specificity than the USPSTF criteria.
A national study by St. Jude Children's Research Hospital found that telephone counseling from advanced-practice nurses more than doubled the likelihood of adult childhood cancer survivors receiving recommended heart screenings. The study showed a significant increase in cardiomyopathy screening rates among participants who received bo...
A comprehensive review of 19,000 scientific papers identified more than 800 cancer-specific biomarkers that could lead to a single blood test for early detection of many types of cancer. The study aims to develop a screening test from a single blood sample for multiple cancer types.
Research shows that primary care providers who know guideline recommendations for low-dose computed tomography (LDCT) screening are more likely to order LDCT for high-risk individuals. This knowledge gap is highlighted by a survey of over 200 primary care providers, which found that 48% knew three or more guideline components.
A new study found that two-thirds of health websites recommending prostate cancer screening aligns with medical organizations' stance. Many online resources advocate for patient-individualized approaches, while some sites advise against screening due to potential risks.
Research by University of Exeter Medical School reveals that systematic testing for Lynch Syndrome in younger bowel cancer patients would identify two-thirds with the condition, avoiding 40 further cases. The test is expected to save lives, money and resources by identifying those at higher risk of developing cancer.
A genetic test for Lynch Syndrome could help reduce the risk of bowel, womb, and ovarian cancers in families. The test would identify individuals who are at higher risk and provide them with risk-reducing measures such as more intensive surveillance to spot recurrences and new cancers early.
The study found a sharp increase in early-stage breast cancer cases among 70-75 year olds after national screening was introduced, suggesting overdiagnosis. The researchers argue that personalized screening decisions based on remaining life expectancy and individual risk factors are necessary to avoid unnecessary overtreatment.
Researchers in Guangdong, China have developed a new non-invasive method to screen for prostate cancer using surface-enhanced Raman scattering (SERS) spectroscopy combined with support vector machine (SVM) analysis. The technique achieved an accuracy of 98.1 percent in identifying cases of cancer.
A third of women in the UK breast screening program do not fully understand the risks of 'overdiagnosis', despite being informed about the concept. Research found that intentions to attend screening remained high despite uncertainty about the information provided.
The pilot program aims to increase colorectal cancer screening rates and follow-up care for patients served by community health centers. Nine national medical professional societies will join forces with the National Association of Community Health Centers and other organizations to support the effort.
A recent study found that states with higher Medicaid payments for office visits have more likely recipients to receive breast, cervical and colorectal cancer screenings. Eliminating asset tests can also increase the likelihood of receiving cancer screenings by helping low-income individuals remain enrolled in Medicaid.
A study examining cancer screening rates in older patients found that those with limited life expectancy still received routine screenings, often without benefit. Screening was more common among married individuals, those with higher education or insurance, and those with a usual place for care.
A UK psychologist has developed a patient tool to assist with lung cancer screening decision-making, aiming to empower individuals to make informed choices about their health. The tool will provide accurate information and calculate personalized feedback, allowing patients to discuss the decision with their healthcare provider.
The American College of Radiology (ACR) disputes systemic patient anxiety concerns related to inconclusive cancer screening test results from computed tomography (CT) lung cancer exams. A study by Gareen et al suggests that anxiety effects are minimal, and the lifesaving benefits outweigh any downsides.
Researchers developed a predictive model to identify carcinogenic chemicals using gene expression response in the liver, improving cancer screening and evaluation processes. The new approach enables accurate and cost-effective screening for over 80,000 chemicals currently in commercial use.
A recent study found that HPV testing alone provides similar reassurance against cervical cancer as cotesting and even more so than a negative Pap test. This suggests that primary HPV testing every 3 years could be an effective screening strategy.
A new study published in JNCI: Journal of the National Cancer Institute found that breast cancer screening costs increased substantially among older women between 2001 and 2009, despite unchanged detection rates of early-stage tumors. The study analyzed data from the SEER-Medicare linked database and found a significant increase in scr...
Researchers analyzed data from over 112 women diagnosed with endometrial cancer, finding no association between soy food or isoflavone intake and the risk of endometrial cancer. The study's findings contradict previous research suggesting potential protective properties of soy foods against endometrial cancer.
A study of over 59,000 patients found that 3D digital breast tomosynthesis increased overall cancer detection by 28.6% and invasive cancer detection by 43.8%. The technology also reduced recall rates in community-based radiology practice.
A recent study found that a 5-year low-dose computed tomography (LDCT) screening protocol can detect lung cancer effectively, with a high proportion of cancers being treated and good long-term survival rates. The results show improved diagnostic performance compared to other studies, including the National Lung Cancer Screening Trial.
The American Cancer Society has released guidelines to support primary care of estimated 2.8 million men with a history of prostate cancer in the US. The guidelines outline posttreatment clinical follow-up care for long-term and late effects, including health promotion, surveillance for recurrence, and management of physical and psycho...
A study found that colorectal cancer rates declined significantly after increasing cancer screening tests. The incidence of late-stage and early-stage cancers decreased, resulting in a reduction of 550,000 cancers during the period.
A study found that smokers are more likely to quit after receiving a serious lung cancer screening result. The effect appeared to be durable, lasting up to 5 years after the last screening.