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New antibodies developed that can inhibit inflammation in autoimmune diseases

Two first-in-class antibodies, C01 and C04, have been developed to inhibit inflammation in autoimmune diseases by blocking the high-affinity IgG receptor FcγRI. The antibodies were discovered using a unique immunization method and exhibit higher affinity for FcγRI than human IgG.

SourceUniversity Medical Center Utrecht·JournalNature Communications·TypeExperimental study·DateNov 19, 2025
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Study suggests no link between antibiotic exposure and autoimmune diseases in children

A large-scale study published in PLOS Medicine found no association between early life antibiotic exposure and the development of autoimmune diseases in children. Researchers analyzed data from over 4 million Korean children and discovered no increased risk of Type 1 diabetes, Juvenile idiopathic arthritis, or other autoimmune conditions.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateAug 21, 2025

Thyroidectomy more effective than medication for Hashimoto disease

Complete surgical removal of the thyroid gland improved symptoms in patients with Hashimoto thyroiditis, including profound fatigue, poor sleep quality, and muscle tenderness. Thyroidectomy also normalized serum antithyroid peroxidase (anti-TPO) antibodies, providing a more effective treatment option for these patients.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateMar 11, 2019
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Hashimoto's thyroiditis can affect quality of life

Researchers found that Hashimoto's thyroiditis symptoms persist even when thyroid function is normal, affecting quality of life. Women with higher levels of anti-thyroid antibodies experienced more symptoms.

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalThyroid·DateFeb 25, 2011