Articles tagged with Ophthalmology
A study published in the Journal of AAPOS found no therapeutic effect of stem cell therapy on children with optic nerve hypoplasia. The research highlights the need for scientifically testing these procedures to validate their effectiveness and ensure safety.
African-American individuals are disproportionately affected by glaucoma, with a four to five times higher risk of occurrence and up to 15 times greater likelihood of significant visual impairment compared to European descent.
Researchers at UCL Institute of Ophthalmology identify LRG1 as a protein responsible for abnormal blood vessel growth in diseases like cancer, macular degeneration, and rheumatoid arthritis. Inhibition of LRG1 may be a promising target for future therapy.
Researchers at the University of Iowa have found that Eylea can effectively treat wet AMD patients who were previously unresponsive to Avastin and Lucentis. After three monthly injections, half of the eyes treated with Eylea showed reduced fluid accumulation, while one in five experienced improved vision.
Researchers at University of Nottingham have identified a previously undetected layer in the human cornea, known as Dua's Layer. This breakthrough discovery could lead to safer and simpler surgical procedures for patients undergoing corneal grafts and transplants.
Rates of childhood squint surgery in England have declined significantly over the past 50 years, with a threefold decrease in admission rates. However, there remains a significant geographical variation in the procedure's use, with areas having the highest and lowest rates showing a fivefold difference.
Researchers found that blocking VEGF-A can decrease intraocular pressure but impair the ciliary body's function. This raises concerns about the long-term effects of aggressive anti-VEGF therapies on eye diseases like wet macular degeneration and diabetic macular edema.
A new study found that up to 40-50% of older adults with eye disease limit their activities due to a fear of falling. This fear leads to social isolation and disability in seniors, emphasizing the need for interventions to help them feel more confident about their abilities.
A new study published in Investigative Ophthalmology & Visual Science found that glaucoma patients read slower when reading silently for long periods, with a 16% decrease in reading speed. The research suggests technological solutions like e-readers could help alleviate reading difficulties, paving the way for potential app development.
Dr. Jonathan Lass will receive the 2012 Paton Award for his outstanding contributions to corneal preservation and clinical eye care. The award recognizes his 30-plus-year career as an ophthalmologist and medical educator at Case Western Reserve University.
Researchers have found that abnormal eye movements in amblyopia are caused by changes in the brain's subcortical regions. The study, published in Restorative Neurology and Neuroscience, suggests that these changes may be an attempt to enhance contrast sensitivity in visually impaired eyes.
A meta-analysis conducted by researchers from China found a strong association between smoking and the risk of age-related cataracts. Current smokers were found to have a higher risk of incidence compared to non-smokers, while former smokers also showed an increased risk of certain subtypes of cataract.
A new Hopkins study found that monthly injections of ranibizumab improve eye chart test results, build driver confidence, and keep those with wet AMD driving longer. This treatment may help elderly individuals maintain their independence by continuing to drive despite vision loss.
Balint's syndrome is a rare neurological disorder that badly impairs a patient's ability to make sense of what they see. Patients experience difficulties with eye movements, arm pointing, and visual field constriction.
Researchers at the Singapore Eye Research Institute and Genome Institute of Singapore have identified three new genes linked to PACG, a leading cause of blindness worldwide. The study used genome-wide association analysis and validation experiments to uncover genetic risk factors for the disease.
Dr. Joseph Ciolino, a Mass. Eye and Ear ophthalmologist, has received the Research to Prevent Blindness (RPB) Career Development Award to support his translational projects in keratoprosthesis and ocular drug delivery. The award aims to attract young physicians and scientists to eye research.
Research suggests women require higher power reading glasses than men of equivalent age due to preferred reading distances or arm length. The study found no significant gender-related difference in the eye's focusing ability.
The Mass. Eye and Ear Cataract Master uses computer-based simulation to provide a realistic interactive experience for ophthalmology residents and practicing surgeons. The program aims to minimize clinical risk while boosting skills and confidence, ultimately raising the quality of patient care.
A study by Loyola University Chicago Stritch School of Medicine found that only 15% of patients with low vision reported being recommended smartphones for their accessibility features. However, 24% of participants used smartphones, which can offer features like font size increase and GPS navigation to enhance quality of life.
Researchers have identified a genetic factor called a trinucleotide repeat as a strong predictor of Fuchs' dystrophy. The study found that unusually long segments of repeated DNA nucleotides in the TCF4 gene cause havoc, impacting the coding of the protein.
A case study highlights the need for ophthalmologists to be vigilant for signs of child abuse in patients with chronic or recurrent keratoconjunctivitis. The patient's symptoms improved but persisted despite treatment, leading to a diagnosis of child abuse.
The Association for Research in Vision and Ophthalmology (ARVO) has announced its 2012 ARVO Award recipients, honoring vision researchers who have made significant contributions to the field of ophthalmology. This year's award winners include Peter Sterling, John V. Forrester, Jeffrey L. Goldberg, and Josh Wallman, who will be recogniz...
A new study by Dr. Chaim Bell at St. Michael's Hospital has revealed huge variations in the charges ophthalmologists impose on specialty lenses used in cataract surgery. Most surgeons charge less than the maximum recommended rate, while others charge significantly more, potentially representing predatory pricing.
Researchers developed a computational technique to correct aberrations in optical tomography, enabling faster, less expensive and higher resolution tissue imaging. The technique was demonstrated using gel-based phantoms and rat lung tissue, resulting in sharp points and clearer tissue structures.
Scientists at University College London have successfully transplanted photoreceptors into adult mice with degenerate retinas, restoring their vision. The study suggests that this approach could lead to effective treatments for thousands of people affected by degenerative eye disorders.
A randomized controlled trial found that bevacizumab treatment improved visual acuity and reduced symptoms of diabetic macular edema compared to traditional macular laser therapy. The study suggests a potential long-term benefit of bevacizumab in managing persistent DME.
Researchers found that corneal thickening occurs in FECD patients before swelling is observed, necessitating regular monitoring and potential surgical intervention. The study's findings have the potential to improve patient care for Fuchs corneal dystrophy.
Patients taking oral fluoroquinolones had a higher risk of developing retinal detachment compared to non-users, with an average number of days from first prescription to event being 4.8 days. The absolute risk increase was small, with 2,500 patients needed to be harmed for every user
The number of ophthalmologists worldwide is insufficient to meet the growing demands of ageing populations and developing countries. The global shortfall of trained eye doctors is a pressing concern, particularly in low-income countries where capacity is increasing faster than the population.
Researchers developed a low-cost digital head posture measuring device using Nintendo Wiimotes to help diagnose ocular torticollis in children. The system demonstrated high accuracy and reliability in measuring head posture, showing promise as a diagnostic tool for ophthalmic patients.
Researchers have made a breakthrough in cultivating stem cells on human corneas, a potential game-changer for patients awaiting corneal transplants. The successful cultivation of stem cells on human corneas could eventually eliminate the shortage of donated corneas, allowing for more people to receive life-changing transplants.
Researchers in British Journal of Ophthalmology reveal that self-inflicted blinding is a rare complication of severe psychosis, such as schizophrenia. The phenomenon has been mistakenly attributed to sexual guilt and the Oedipus complex, but cultural beliefs are not a plausible explanation for this behavior.
Age-related macular degeneration (AMD) cases in the UK are projected to increase by a third by 2020, with 679,000 individuals affected. The majority of these cases will be in women, and prevalence rates will rise sharply with age.
The ARVO Foundation for Eye Research has awarded $40,000 fellowships to Balamurali K. Ambati and Stephen H. Tsang to conduct age-related macular degeneration (AMD) research. The fellowships aim to develop therapeutics and personalized medicine approaches for AMD.
A study published in Archives of Ophthalmology found that commercial insurance was the most frequent payer of emergency department outpatient services in Florida, followed by self-pay and Medicaid. The data suggest a shift towards Medicaid as patients move into eligible categories, which may impact eye care delivery models in the state.
A new UCSF study shows a popular antibiotic treatment for trachoma can be administered every six months, reducing treatment costs and potentially treating twice as many patients. Researchers found a significant decrease in trachoma prevalence, even elimination in some villages, regardless of treatment frequency.
A recent study published in Ophthalmology found that astronauts who spent long durations in space experienced swollen optic nerves, distorted eyeball shapes, and retinal changes. The study also revealed that many astronauts experienced worsening of distance or near visual acuity after flight.
Researchers identified a specific rare mutation, CFH R1210C, associated with advanced AMD and visual loss in patients. This discovery suggests that loss of CFH function drives AMD risk, pointing to new treatments for high-risk individuals.
A recent British study published in Investigative Ophthalmology & Visual Science may revolutionize the way healthcare professionals assess glaucoma risk. The study used a new method to measure intraocular pressure, correcting for corneal biomechanics, and found accurate measurements of eye pressure with improved accuracy.
A recent study published in Investigative Ophthalmology & Visual Science found a strong association between physical fitness and reduced glaucoma risk. The research discovered that moderate physical activity can lower the risk of low ocular perfusion pressure, a key factor in glaucoma development.
A UCSF study found significant vision improvement in patients with severe bacterial corneal ulcers who received steroid therapy. Researchers tested 500 participants from the US and India, and results showed no harm but a benefit for those with more serious forms of ulcers.
New research by University of Kentucky investigators found that short-interfering RNAs can induce retinal degeneration via TLR3 and IRF3. This discovery highlights the need for caution when designing or using siRNAs intended for eye treatment.
The Massachusetts Eye and Ear Infirmary has received a $11 million grant from the National Institute of Allergy and Infectious Disease to coordinate a Harvard-wide project on antibiotic resistance. The goal is to develop new antibiotics to treat highly resistant infections caused by staph and other related bacteria.
A new device called myVisionTrack has been developed to monitor degenerative eye diseases such as age-related macular degeneration and diabetic retinopathy. The hand-held device allows patients to track changes in their vision over time with high accuracy, enabling timely treatment and preventing preventable vision loss.
Researchers found that African-Americans with glaucoma have significantly higher oxygen levels in their eyes compared to Caucasians. This suggests that excess oxygen may damage the drainage system and lead to elevated pressure, causing optic nerve damage and vision loss. Further study is needed to confirm this association.
A recent study by Schepens Eye Research Institute found that a bioptic telescope on one lens of glasses used for low vision driving may not prevent the wider view of the road with the second eye. The study, published in May 2011 Archives of Ophthalmology, suggests that individuals wearing such telescopes can detect targets in the area ...
The Association for Research in Vision and Ophthalmology (ARVO) honored its 2011 Award recipients, including Robert E. Anderson, Paulus de Jong, James T. Rosenbaum, Andrew J. Fischer, and Gullapalli N. Rao, for their groundbreaking research on photoreceptors, retinal diseases, intraocular inflammation, myopia, and vision-guided ocular ...
This year's class of distinguished fellows recognizes outstanding leadership and service in vision research. The ARVO Fellows will be officially inducted at the Association's Annual Meeting, May 1, 2023.
Researchers from University of Granada successfully created the first bioartificial organ in Spain by replacing pig corneal cells with human stem cells. The new organ maintains the basic structure of the cornea while replacing its cellular components.
A global consensus report defines meibomian gland dysfunction as a chronic, diffuse abnormality affecting the tear film. The report proposes a universal classification system and diagnostic tests to aid clinicians in diagnosing and managing MGD-related disorders.
Karl Deisseroth, a Stanford University associate professor, is being recognized for his pioneering work in developing and using optogenetic approaches to study neuronal function. His technique has had far-reaching impact on ophthalmology and vision science.
A retrospective cohort study found that patients with retinal vein occlusion (RVO) had an almost two-fold higher incidence of stroke compared to age- and sex-matched controls. The study suggests that RVO may be associated with an increased risk of cerebrovascular accidents but not myocardial infarctions.
A recent study published in Investigative Ophthalmology & Visual Science found that a drop in temperature below 30 degrees Celsius can cause the meibum to become too thick and stiff, leading to dry eye suffering. This effect is exacerbated by wind, which accelerates the drop in temperature of the ocular surface and eyelids.
A survey of UK medical schools found that most do not fully comply with the International Council of Ophthalmologists' recommended curriculum for ophthalmology. Only four schools taught all 13 formal teaching topics, and no school taught all 10 recommended clinical skills.
Dr. Douglas A. Jabs has been recognized by the American Academy of Ophthalmology with the Jackson Memorial Lecture for his decades-long study on cytomegalovirus retinitis and its interaction with HIV. His research aims to improve clinical outcomes in patients with AIDS and CMV retinitis.
A recent study in the Journal of AAPOS found that feeding premature infants one hour before their retinopathy of prematurity (ROP) examination unexpectedly reduced stress levels. The researchers also discovered that this practice did not increase vomiting or gastric aspirates, contrary to current practice.
Research published in the British Journal of Ophthalmology found that children aged 6 and older are significantly less likely to invite peers with a visible squint to their birthday party. This discrimination may have lasting psychological impacts on individuals concerned.
Researchers at UMass Medical School have found valproic acid to halt vision loss in patients with retinitis pigmentosa, a severe neurodegenerative disease that causes blindness. The study suggests that low-dose valproic acid could be an effective treatment for photoreceptor loss associated with RP.
Researchers have developed a non-invasive imaging tool to study the retina of live birds of prey, producing detailed images for the first time in history. The new spectral-domain optical coherence tomography (SD-OCT) system shows unprecedented three-dimensional information about the retina's layers and structure.
Dr. Hui Shao has received a grant from the Research to Prevent Blindness organization to study Sjogren's syndrome, a chronic autoimmune disease affecting millions of Americans. Her team has discovered a protein called Klk22, which may play a role in the development of the disease.