Articles tagged with Pediatrics
Researchers found that two HIV vaccine trials stimulated a critical immune response in infants, which has been linked to reduced HIV infection. The findings suggest that infant vaccination can elicit a robust anti-HIV envelope IgG immune response and highlight the importance of including pediatric populations in vaccine studies.
Pediatric atrial fibrillation is a rare but serious condition with substantial symptoms and a high recurrence rate. Researchers found that nearly 40% of patients experienced recurrence, with significant complications in three cases.
A study published by University at Buffalo found that early-term infants (born at 37-38 weeks) are more likely to experience low blood sugar, difficulty breathing, or require antibiotics, necessitating NICU admission. The risk is further increased if born via cesarean section.
A study by Tel Aviv University researchers reveals that nearly all pediatricians in Israel strongly support the vaccination of infants, with 92% agreeing it is in their best interest. However, 37% also agree that parents have a right to decide on medical care for their children.
A study found that bed sharing increased among black and Hispanic families, with black infants sharing beds most often. The percentage of black infants usually sharing a bed increased from 21.2% in 1993 to 38.7% in 2010.
A study published in Journal of Neurotrauma found that traumatic brain injury during childhood can cause significant deficits in working memory. The authors propose identifying neuroanatomical biomarkers to detect early signs of impaired working memory.
The National Institute of Allergy and Infectious Diseases has renewed a 10-year contract with the University of Maryland School of Medicine's Center for Vaccine Development, providing up to $135 million in annual funding. The center will conduct basic research, clinical studies, and vaccine development to combat existing and emerging i...
A new study uses a computer-based decision support system to deliver personalized evidence-based recommendations for pediatricians, increasing the likelihood of accurate ADHD diagnoses. The system, CHICA, also prompts physicians to screen for anxiety and depression.
Researchers at Johns Hopkins Children's Center found that blood transfusions were needed in less than 3% of pediatric non-cardiac surgeries. In many cases, unnecessary testing and supply waste occurred due to precautionary measures. The study suggests that surgeons should assess each patient's specific needs for blood screening instead...
The new guidelines provide standardized guidance and educate staff and volunteers on the principles of infection prevention to reduce the risk of infection for children and families in pediatric residential settings. The guidelines include practices such as standard precautions, health screening, and mandatory vaccination practices.
A new study by UC San Diego researchers reveals that the pancreatic protein Nkx6.1 is crucial for regulating insulin biosynthesis and secretion in beta cells. The study found that impaired Nkx6.1 levels contribute to the pathogenesis of type 2 diabetes, leading to rapid onset of diabetes in mice.
A large study found that 4% of head-trauma scans have unexpected results, ranging from benign to life-threatening cancers. Doctors should weigh patient rights against financial costs and anxiety when dealing with incidental findings.
A multi-institutional study found that a unique quality improvement methodology can effectively evaluate chest pain in children using minimal resources. The Standardized Clinical Assessment and Management Plans (SCAMPs) algorithm identified cardiac causes of chest pain while reducing testing utilization, with only 1% of patients having...
Children's National Hospital has received a five-year NIH grant to identify reliable early signs of prenatal brain injury in congenital heart disease. The study aims to develop non-invasive methods to detect high-risk cases before birth, opening windows for new treatments to prevent impaired brain development.
Children's Mercy Hospital will assess the benefits of rapid genome sequencing in diagnosing acutely ill babies, with a focus on improving speed and cost-effectiveness. The grant aims to evaluate the use of STAT-Seq technology to help physicians make timely diagnoses and provide families with answers quickly.
A recent study at Le Bonheur Children's Hospital found that Pedi-Flite improved outcomes for pediatric diabetic patients, reducing the need for hospital admissions. The system also saved over $760,000 by avoiding 439 ED visits and 115 admissions.
A study found significant variability in pediatric DNR orders, with most clinicians limiting resuscitation to cardiopulmonary arrest, but actually varying their approach. Clinician attitudes and behaviors regarding DNR orders can impact patient care.
A new study published in Pediatrics found that pediatric readmission and revisit rates are limited in their usefulness as a quality indicator for pediatric hospital care. The study suggests that grouping patients with similar diagnoses could improve the accuracy of readmission rates as a quality measurement.
A new paper aims to educate pediatricians on recognizing and responding to caregiver-fabricated illness in children, which can include physical and psychiatric symptoms, and carries significant mortality rates.
Researchers at Johns Hopkins Medicine developed a 3D computer model that analyzes a child's unique anatomy and pinpoints the best location for a defibrillator before implantation. The virtual heart model predicts optimal device placement in children with tiny or malformed hearts, reducing repeat procedures.
Recent studies suggest that HB-EGF can protect the intestines from various types of injury, including those caused by radiation therapy. The protein's ability to decrease harmful substance production and promote cell growth makes it a promising therapeutic option for treating necrotizing enterocolitis in newborns.
A recent study found that children with amplified chromosome 21 are at higher risk of treatment failure, but not worse outcomes, than those without the genetic abnormality. Recognizing this amplification could lead to improved cure rates in low-risk patients treated aggressively.
New study published in Journal of Hospital Medicine outlines top recommendations for improving healthcare value, including reducing unnecessary tests and procedures. The recommendations aim to lower costs and lead to better care for patients, particularly children and adults hospitalized with respiratory illnesses.
A new study from the University of Michigan researchers found that children with higher BPA levels had a higher odds of obesity and adverse levels of body fat. The study measured BPA levels in children's urine and found an association between high BPA levels and abnormal waist circumference-to-height ratio.
The study found that the proportion of patients on antiretroviral therapy (ART) has increased, with virologic suppression rising from 35.5% to 63%, among perinatally infected HIV patients now approaching adulthood. However, older patients are more likely to experience higher viremia and advanced immunosuppression.
Researchers at the University of California, San Diego, have decoded the genetic basis of chronic mountain sickness, a disease affecting Andean highlanders. They found two genes, ANP32D and SENP1, that are overexpressed in CMS individuals and may hold key to treating the condition.
A study published in Critical Care Medicine found that telemedicine consultations significantly improve the quality of care for seriously ill and injured children treated in remote rural emergency rooms. The research showed that patients' satisfaction and perception of their child's care are also improved when consultations are provide...
Cases of children ingesting magnets led to a quintupling of incidents between 2002 and 2011. Ingestion of multiple magnets resulted in more severe outcomes, including emergency surgery.
A new statistical model designed for children can accurately discriminate performance among hospitals and adjust for patient risk factors. The program has been tested with data from 46,281 patients under 18 at 43 institutions in 2011 and shows promise for improving surgical outcomes.
Children's perceptions of living with asthma may differ significantly from those of their caregivers, a new study shows. The study found that both children and caregivers should be interviewed during doctor visits to ensure accurate understanding of the child's condition.
A new study reveals that pressure ulcers in children are more common than previously thought, with medical devices such as facemasks and pulse oximeters identified as major contributors. Cincinnati Children's researchers developed a quality improvement initiative that reduced pressure ulcers by 50 percent.
A new study found that pediatric cancer patients who have central lines at home develop nearly three times as many bloodstream infections as those treated in the hospital. The research highlights the need for better understanding and designing infection-prevention strategies for at-home central line care.
A new review highlights recent advances in the scientific understanding of bitter taste to improve drug acceptance and compliance in pediatric populations. The paper focuses on applying this knowledge to formulate pediatric medications that are more palatable for children.
A study found that parents with established relationships with pediatricians often choose retail clinics for minor illnesses due to convenient hours and lack of office appointments. The most common reasons for using retail clinics were acute upper respiratory tract illnesses, such as sore throats and ear infections.
A study published in PNAS found that dampening a feedback loop between a DNA repair checkpoint and its controlling pathways may promote tumor growth in pediatric solid tumors. This discovery provides new insights into the cause of childhood cancers and offers a potential target for future therapies.
A new study published in Pediatrics reveals that over 25% of children with cerebral palsy suffer from moderate to severe chronic pain, limiting their activity. Pediatricians should focus on identifying and treating the underlying causes of pain to improve health and quality of life for these children.
The Damon Runyon Cancer Research Foundation has named four outstanding young scientists to tackle cancers in children and young adults. The award provides funding for basic scientists and clinicians conducting research with the potential to significantly impact pediatric cancer prevention, diagnosis, or treatment.
A Vanderbilt research program trains community pediatricians to diagnose autism, leading to a significant increase in diagnoses within their practices. The training improved diagnostic accuracy and shifted the comfort level of discussing ASD diagnoses with caregivers.
A study of 9,000 preschoolers found that those with shorter than average sleep times had higher rates of 'externalizing' behavior problems. The researchers recommend discussing steps to improve sleep habits for children with behavior problems.
Researchers from LSUHSC report that children sedated with meperidine and hydroxyzine experienced vomiting, prolonged sleep, and irritability, while those sedated with midazolam had fewer side effects. The study recommends educating parents on safe medication use and post-procedure care to improve child safety and comfort.
Dr. Gary Mathern, a pediatric neurosurgeon at UCLA, was honored with the Ambassador for Epilepsy Award for his significant work in improving clinical care for children with medically refractory epilepsy. His research has led to breakthrough discoveries on mechanisms of the disease process and how seizures develop in the brain.
The American Thoracic Society has released a statement on adult and pediatric controlled organ donation after circulatory determination of death (DCDD), aiming to guide stakeholders involved in the process. The statement emphasizes respect for dying patients and their families, while promoting the recovery of viable organs.
The World Health Organization's new guidelines call for immediate antiretroviral therapy (ART) for all HIV-infected children under five years of age. DNDi and Cipla are expediting the development of urgently needed 4-in-1 ARVs adapted for babies and toddlers with HIV, to be delivered by 2015.
Researchers found a 65% increase in IBD hospital discharges from 2000 to 2009, with specific increases seen in Crohn's disease and ulcerative colitis. The study suggests an unclear reason behind the trend, with potential contributors including increased disease severity and co-existing conditions.
A study by MassGeneral Hospital for Children found that pediatric practices can effectively implement a smoking cessation program for parents, reaching nearly half of smoking parents. The program, CEASE, was trained in 20 practices and resulted in significant increases in tobacco control assistance and physician referrals.
Researchers aim to improve treatment and rehabilitation strategies for children with spinal cord injuries using diffusion tensor imaging (DTI). The study plans to enroll 100 children, including those with spinal cord injuries and healthy controls.
A large clinical trial shows that clopidogrel does not effectively reduce shunt-related blood flow issues in infants with congenital heart diseases. Aspirin alone may be effective in reducing the risk of clot formation, while switching to Plavix is not recommended.
Research by Dr. Robert Wyatt and his team provides insights into the molecular mechanism of IgA nephropathy, a common kidney disease in North America. The study's findings suggest noninvasive tests for diagnosis and monitoring, potentially leading to improved treatment outcomes for patients.
A multidisciplinary approach combining preventive measures and regular monitoring significantly reduced ventilator-associated tracheobronchitis (VAT) infections in pediatric intensive care patients. The initiative, implemented at Nationwide Children's Hospital, resulted in a 53% drop in VAT cases compared to pre-intervention rates.
Hyundai Hope on Wheels has awarded a $75,000 Hyundai Scholar Grant to Dr. Vivian Chang at UCLA's Children's Discovery and Innovation Institute to support her research on DNA sequencing technology for identifying cancerous genes in children. The grant will enable oncologists to design personalized surveillance programs using advanced to...
A study by The Children's Hospital of Philadelphia found that educating pediatricians about appropriate antibiotics for common respiratory infections led to a significant decrease in broad-spectrum prescribing. This intervention improvedRx guideline compliance, resulting in better antibiotic use and potentially reduced resistance.
The use of CT scans in pediatrics has significantly increased over the last two decades, exposing children to higher doses of ionizing radiation linked to an increased risk of cancer. The study estimates that 4,870 future cancers could be caused by pediatric CT scans performed annually.
A new study reveals that medical devices contribute to complications in children with complex medical conditions. The research found that vascular access devices and nervous system devices were the most common types of devices associated with adverse events, which often affected young children under the age of 2.
A new study published in The Journal of Pediatrics found that most youth football player concussions occur during games, not practice sessions. Players aged 11-12 years were almost three times more likely to suffer a concussion than those aged 8-10 years.
A new study found that 9% of pediatric and adolescent heart transplant recipients experience non-adherence within two years of receiving their transplant. The risk of mortality among non-adhering patients is significantly higher, with a 26% chance of death within one year and 33% within two years.
A new study from the University of California - San Francisco found that African-American and Latino children are increasing their consumption of 100 percent fruit juice, which often has just as much sugar as soda. The study suggests that parents need more education on healthy beverages to replace sugary drinks with water or milk.
A new international study found that prolonged, intense initial treatment in children with multi-system Langerhans cell histiocytosis (MS-LCH) can achieve survival rates as high as 84 percent. The study also showed a significant reduction in disease reactivation rate compared to shorter treatment periods.
UCLA will study the use of videoconferencing technology to deliver integrated behavioral and mental health services to children in community primary care settings. The project aims to provide effective, efficient, and family-centered care to children in low-income communities.
A study found an increase in unintentional marijuana ingestions among children following Colorado's new drug laws, with most cases involving medical marijuana products. The authors recommend public health interventions and increased awareness among healthcare providers to mitigate this issue.
A study analyzing top box-office movies found that tobacco brand producer placements decreased significantly after the Master Settlement Agreement, but alcohol brand placements increased in movies rated for youth audiences. This trend has implications for teen drinking and substance use behaviors during adolescence.