The St. Jude Children's Research Hospital has released the world's largest comprehensive human cancer genome data, exceeding volume of all other sources combined. This valuable information is available for free access by researchers, accelerating disease research and potentially leading to new treatment options for childhood cancers.
A new study suggests that a significant proportion of children with asthma failing Step 4 or greater therapy may have severe asthma with fungal sensitization. Children with this condition were found to be older, have higher serum IgE levels, and perform worse on pulmonary function tests compared to those without the condition.
Researchers found that clots are extremely rare in otherwise healthy children who suffer traumatic fractures. The study suggests that preemptive anti-coagulant medications should be reserved for children with underlying conditions that increase clotting risk.
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Dr. Yael Mosse will be honored with the first James B. Nachman ASCO Junior Faculty Award in Pediatric Oncology at the ASCO Annual Meeting. Her groundbreaking research on neuroblastoma has led to major advances in treatment, including a national clinical trial of a new drug treatment.
Researchers discovered that underweight babies are more likely to become obese due to a disrupted hypothalamus, which leads to an increased appetite for calories. This results in the child consuming more calories to catch up on lost nutrition in utero, potentially leading to childhood obesity.
A study by Wake Forest Baptist Medical Center found limited use of family theories in pediatric obesity research, but suggests that increased use could lead to better treatments. The researchers propose a new approach that incorporates the entire family into treatment, rather than just focusing on individual patients.
The study found that dedicated pediatric imaging departments significantly reduce radiation doses in pediatric CT scans, with compliance rates improving and patient doses decreasing. The use of specialized technologists and protocols tailored to child size and organ system scanned contribute to these benefits.
A study found that 53% of children with asthma were exposed to secondhand smoke, resulting in higher odds of healthcare visits and sleep disturbances. This highlights the need for improved education and tools to help families reduce exposure and promote better health outcomes.
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A study by Oregon Health & Science University found that restricting pacifiers in a hospital setting decreased exclusive breastfeeding rates and increased formula consumption in breastfed infants. The researchers argue that the effect of pacifier use on breastfeeding has not been well-established, warranting further scientific inquiry.
A new study shows that MR enterography outperforms CT enterography in diagnosing fibrosis and detecting active inflammation in pediatric Crohn's patients. The imaging modality offers a radiation-free alternative to traditional CT scans.
Researchers found a link between compulsive cell phone use and increased risk of motor vehicle crashes. A study showed that anticipating calls or messages can be an additional source of distraction contributing to crashes.
A recent study by the American Academy of Pediatrics reveals that youths with special health care needs are more likely to experience symptoms of anxiety or depression if they feel left out or bullied by their peers. The study found that ostracism was the strongest predictor of increased symptoms, highlighting the need for clear polici...
Research suggests that maternal stress during the first trimester of pregnancy can lead to lower iron levels in newborns, which may result in physical and mental delays. The study found a significant correlation between mothers' stress levels and their babies' cord-blood ferritin concentrations.
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A new study finds that adolescents and young adults who recognize TV ads for quick-service restaurants are more likely to be overweight. The researchers surveyed 3,342 youths ages 15 to 23 years and found that those who recognized more ads were over twice as likely to be obese compared to those who recognized few ads.
A teen-led study using simulators found that texting while driving poses significant risks, with drivers making more mistakes when their phones are in view or hidden. The research suggests that there is no 'safe' way to text and drive, emphasizing the need for stronger laws and education.
A recent study presented at the Pediatric Academic Societies annual meeting found a significant link between recognition of TV alcohol advertisements and underage drinking. The study showed that 59% of underage youths previously drank alcohol, with those familiar with TV ads more likely to engage in binge drinking.
A recent study by the American Academy of Pediatrics found that adolescent violence can be attributed to parental attitudes and behaviors. Teens who fight often model what they see adult relatives do, highlighting the importance of involving parents in prevention programs.
Research shows that nearly one-third of apartment dwellers report smelling tobacco smoke in their buildings, with children being more vulnerable. A smoke-free building is crucial to protect shared indoor air, and residents receiving government housing subsidies are more likely to experience exposure.
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A study found that 24% of low-income mothers add cereal to bottles, increasing their children's risk of obesity. Mothers with depressive symptoms are more likely to engage in unhealthy feeding practices.
A study presented at the Pediatric Academic Societies annual meeting found that nearly one-third of parents have low reading skills and 83% have poor numeracy skills. Parents who scored below the third grade level on a math test were five times more likely to make dosing errors.
A computerized system helped identify adolescents in need of Chlamydia and N. gonorrhea testing in a pediatric emergency department, nearly doubling testing rates. Patients found the electronic survey quick and easy to use, with high satisfaction rates.
A study of low-income mothers with infants found a connection between food insecurity and restrictive feeding practices, which can disrupt hunger regulation and lead to obesity. Mothers experiencing food insecurity were more concerned about their child becoming overweight than those who weren't struggling with food access.
A study published at the Pediatric Academic Societies annual meeting found that family presence did not hinder trauma teams' ability to treat injured children. The research evaluated the effect of family presence on the trauma teams' ability to identify and treat injuries during the initial phase of care.
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A study by the American Academy of Pediatrics found racial differences in the care of children in emergency departments. Black children are less likely to receive pain medication for severe abdominal pain compared to white patients. This disparity has significant implications for equal access to high-quality healthcare.
A study found a large discrepancy between global disease burden in children and the amount of clinical trial research devoted to this population. Only 12% of clinical drug trials are pediatric trials, despite children bearing nearly 60% of the disease burden for high-priority conditions.
A study found that CT exams increased among pediatric patients with non-traumatic abdominal pain in emergency departments from 1999 to 2007, while ultrasound use remained stable. This trend is concerning due to the potential risks of radiation exposure on children.
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A recent Vanderbilt University Medical Center study found little vertical transmission of MRSA from mother to child, but babies closely matched their mother's carrier status within six weeks after birth. The study suggests that close contact may lead to horizontal transmission of the bacteria.
A study of preschoolers reveals parents of both healthy-weight and overweight children are aware of dietary risk factors but undervalue physical activity. The researchers emphasize the need for pediatricians to provide tailored guidance on how to apply this knowledge in daily practice.
A study published in Journal of Hospital Medicine reveals that 82% of PICU bed-time is used for value-added purposes, while 75% of full PICUs have at least one non-value-added bed. The research provides an understanding of opportunities for improvement to optimize patient flow and resource utilization.
Researchers at IU School of Medicine and Regenstrief Institute created an automated system called CHICA to streamline pediatric care. CHICA uses risk factor data to alert physicians to potential issues, allowing them to focus on individual children's needs.
The American Society of Pediatric Otolaryngology (ASPO) annual meeting featured new research on pediatric ear, nose & throat health. The Presidential Keynote Lecture focused on personalized medicine, highlighting the importance of variation in practice and unwarranted interference. Innovative treatments for laryngotracheal stenosis (LT...
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A new study from Johns Hopkins Children's Center found that children with cerebral palsy experienced the highest blood loss during corrective spine surgery, while those with idiopathic scoliosis had the least. The study analyzed 617 cases of children aged 10-18 and revealed a link between underlying conditions and blood loss.
R. Rodney Howell, a prominent pediatrician and geneticist, has been honored with the 2012 American College of Medical Genetics Foundation Lifetime Achievement Award for his work in newborn screening and genetic research. He is recognized for his leadership role in developing and advancing the program.
A new study found that nearly half of U.S. preschoolers do not have a single parent-supervised outdoor play opportunity per day. Parents are the greatest influence on children's behavior, and research highlights the importance of promoting active healthy living through outdoor play.
Researchers found that moderately regulated calorie intake during infancy reduced the likelihood of becoming obese, contrary to previous studies. Early dietary interventions may have long-lasting effects into childhood and adult life.
A study published by the JAMA Network found that about half of preschoolers lack daily parent-supervised outdoor playtime, with significant disparities among racial and ethnic groups. Regular outdoor play was associated with improved physical health and development outcomes, as well as reduced TV viewing time.
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Dr. Harry Dietz has been recognized for his groundbreaking work on Marfan syndrome, an inherited connective tissue disorder that affects approximately 1 in 5,000 people worldwide. His research has identified the genetic cause of the disease and a potential treatment using an FDA-approved high blood pressure medication.
A new diagnostic criteria for Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) has been proposed, expanding on existing criteria for Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus (PANDAS). A clinical trial testing an immune-based treatment is currently underway, aiming to provide appropriate care fo...
A University at Buffalo study found that parents of pediatric cancer patients distrust online sources of health information and fear what they might encounter. Despite the accessibility of online medical information, caregivers preferred to receive information from trusted healthcare providers rather than the internet.
The number of ADHD diagnoses among American children has increased by 66% over the past decade, according to a new study published in Academic Pediatrics. Specialists are now treating an increasing proportion of these young patients, shifting away from primary care physicians.
A recent University of Washington study found that pediatricians who exhibit unconscious racial bias tend to prescribe better pain-management for white patients than they do for African-American patients. The study suggests that incorporating awareness of personal bias into medical education and training is necessary to avoid unintende...
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Researchers call for ob-gyns to evaluate patients' exposure to environmental chemicals, provide education, and advocate for policy change to reduce toxic exposures. The human reproductive system is vulnerable to biological changes caused by chemicals during critical periods of development.
A network approach improved outcomes for children with inflammatory bowel disease (IBD), increasing remission rates from 55% to 68%. The ImproveCareNow network implemented quality improvement efforts, leading to improvements in care processes and patient outcomes.
Researchers have developed an early warning algorithm to detect children's early cardiac deterioration before inpatient arrest. Additionally, studies suggest that patients with conotruncal defects should be screened for chromosome 22q11.2 deletion syndrome, which can improve treatment outcomes.
A study of Latina mothers found that their primary concern is a strong relationship with their pediatrician, rather than language ability. Mothers valued warm and caring providers who take the time to examine and care for their children.
A Kaiser Permanente study found that computer-assisted decision tools in electronic health records substantially improve the identification and diagnosis of overweight and obesity among children and adolescents. The prevalence of childhood obesity has increased sharply, with at least 18 percent of 12- to 19-year-olds now considered obese.
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A study by Nationwide Children's Hospital found that children with inflammatory bowel disease (IBD) experience more school difficulty than healthy children, mainly in regard to school absences. Internalizing problems are a significant predictor of absences and school-related quality of life.
A new study identifies African-American background, longer NICU stay, and poor access to healthcare as increased risks of death in preterm infants after being discharged from the NICU. Maternal exposure to antibiotics during pregnancy decreases infant mortality risk.
According to a Yale University study published in Pediatrics, over 4,500 US children were hospitalized due to child abuse in 2006, resulting in 300 deaths. Children under one year old were at highest risk of hospitalization, and those on Medicaid had rates six times higher than non-Medicaid patients.
The study advances understanding of bruise composition and age through spectroscopic measurement and Monte Carlo modeling. Researchers developed a multilayered model simulating seven skin layers, providing clearer spectroscopic pictures of bruise composition and age.
The Pediatric Emergency Research of Canada team has made significant advances in treating childhood conditions like croup, bronchiolitis, and mild head injuries. Their research has led to substantial improvements in treatment outcomes and reduced healthcare costs.
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Researchers tested ice hockey, alpine ski, and bicycling helmets to protect young children's heads during winter sports. The study found that no helmet provided adequate protection for all types of impacts, highlighting the need for a new type of winter play helmet.
A study by Boston Children's Hospital reveals that neurologically impaired children account for increasing hospital resources in children's hospitals, with 25% of bed days and 29% of hospital charges attributed to them. This highlights the need for improved care coordination and better patient outcomes.
US study finds that nearly three-quarters of headphone-wearing pedestrian injuries are fatal, mostly among young adult males and under 30 years old. Headphones can mask warning sounds, leading to distraction and sensory deprivation, increasing the risk of accidents.
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A pediatric research project aims to collect long-term clinical data on children with conditions detected in newborn screening, enabling researchers to develop new tests and interventions. The project has the potential to transform treatments for rare childhood diseases.
A new study by the Johns Hopkins Center for Injury Research and Policy found a significant decline in pediatric drowning hospitalizations, with rates decreasing 51% from 1993 to 2008. The study suggests that public efforts to reduce drowning risk, such as pool fencing and swim lessons, may have contributed to this decrease.
A simulation model suggests that implementing latest WHO guidelines requires improving access to care and medications, increasing retention of women in care, and supporting adherence to drugs to eliminate pediatric HIV in Zimbabwe.
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The article highlights the importance of justification and optimization of pediatric CT protocols to reduce radiation dose. Experts recommend using lower tube current, restricting scan length, and employing image post-processing techniques to minimize radiation exposure while maintaining diagnostic quality.
The Damon Runyon Cancer Research Foundation and the Sohn Conference Foundation have partnered to support young scientists tackling childhood cancers, with a focus on preventing devastating illnesses in children and young adults. The partnership aims to recruit top young minds to research childhood cancers, leveraging the success of exi...
A new study recommends using the body mass index (BMI) method to calculate expected body weights in children with eating disorders. The research found that this method is more accurate than others and can account for varying heights and weights, making it a valuable tool for clinicians and researchers.