Articles tagged with Risk Factors
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that one spouse's excess drinking can help protect the other from developing alcohol dependence. The study analyzed twins and their spouses to determine if non-random mating (choosing a mate similar in personality and behaviors) contributes to higher rates of alcoholism among partners.
Researchers at University of Texas M. D. Anderson Cancer Center developed a lung cancer risk assessment tool using standard clinical and epidemiological data. The model assigns a score assessing a person's risk for the disease, with a prediction level of about 60 percent.
A study found that exercise can improve aerobic fitness and reduce cardiovascular disease risk in people with mild to moderate multiple sclerosis. After an eight-week aerobic cycling regimen, participants showed significant improvements in aerobic fitness, triglyceride levels, and resting blood pressure.
The Healthy Heart Handbook for Women provides practical suggestions for reducing heart-related problems and includes warning signs of a heart attack. The handbook offers tips on following a nutritious eating plan, physical activity program, and quitting smoking to reduce risk factors.
A scoring system based on weight, gender, age, blood pressure and clot risk accurately predicts patient mortality after gastric bypass surgery. The system categorizes patients as low-risk, medium-risk or high-risk, with those in the high-risk group facing a six times higher mortality rate.
A U of M-led study has identified 10 new genetic risk factors for type 2 diabetes, which could lead to the development of new drugs and more effective treatments. The findings also improve our understanding of how these genetic factors interact with lifestyle factors.
Researchers have identified at least four new genetic variants associated with increased risk of diabetes and confirmed the existence of six more, boosting the number of known genetic variants to 10. These findings may lead to personalized medicine approaches by exploring how these genetic factors interact with lifestyle factors.
A study found that specific genetic variants in genes CFH and LOC387715 are associated with an increased risk of progressing to advanced age-related macular degeneration. Smoking and high body mass index further increase the risk, but healthy lifestyle habits can reduce it.
Researchers found HIV-infected patients had a higher incidence of heart attacks and major cardiovascular risk factors compared to noninfected patients. The study's findings indicate that HIV-infected individuals should be assessed for cardiovascular risks and that strategies to modify those risks are urgently needed.
A new study from Cornell University finds that adolescents exposed to chronic risk factors experience stress-induced physiological strain, but with responsive mothers, this toll is significantly reduced. The study also reveals that cardiovascular systems of youths are compromised regardless of their mothers' responsiveness.
A consortium of Canadian and American researchers have identified three major genetic risk factors for Crohn's disease: PHOX2B, NCF4, and ATG16L1. These findings highlight biological pathways not previously thought to play a role in the disease, including altered reactive oxygen species production and autophagic processes.
A new study by NHLBI found that elevated risk factors in young adulthood significantly increase the risk of developing coronary calcium, a predictor of heart disease. Young adults with above-optimal levels of risk factors are two to three times more likely to develop coronary calcium than those with lower levels.
A large cross-sectional survey found that frequent consumption of cured meats is associated with lower lung function test scores and increased odds of developing chronic obstructive pulmonary disease (COPD). The study suggests that high dietary nitrite intake may be a novel risk factor for COPD.
A USC study found that patients with later stage cancer diagnoses were more likely to live in unsafe neighborhoods, use public transportation, and travel long distances to receive medical care. The study suggests that addressing neighborhood conditions and prioritizing health care can help reduce late-stage cancer diagnoses.
A research team has identified several novel genetic variations associated with the risk of Crohn's disease, which could improve understanding of the disease process and lead to new therapies. The study found that one of the newly identified genes, ATG16L1, plays a crucial role in autophagy, a biological pathway involved in inflammation.
A recent study failed to validate the association of 85 genetic variants with increased risk for acute coronary syndromes (ACS), including heart attack and angina. The research included 811 patients with ACS, but found no conclusive evidence supporting the use of these gene variants as risk factors in clinical care.
Research suggests individuals with diabetes may have a higher risk of developing mild cognitive impairment, which affects thinking and learning abilities. The study found that diabetes was associated with a significantly increased risk of amnestic mild cognitive impairment, particularly in African-American and Hispanic populations.
A detectable PSA level is first indicator of recurrent prostate cancer after radical prostatectomy, with a doubling time of less than three months indicating imminent death from prostate cancer. Patients with longer doubling times are at significant risk for disease recurrence and cancer-specific death.
A study found that individuals without health insurance are more likely to forego routine physical exams and have a higher risk of unawareness of high blood pressure, diabetes, or high cholesterol levels. Hypertension is the most powerful risk factor for stroke, and those without insurance had poorly controlled hypertension.
A recent study by Johns Hopkins Medicine found that African Americans have weaker muscle contraction in three main regions of the heart, increasing their risk of heart failure. In contrast, Chinese Americans' hearts had a stronger squeezing function and contracted more quickly than other ethnic groups.
Research on silent myocardial ischemia shows that anti-anginal therapy, combined with risk factor control, improves outcomes and preserves left ventricular function. Additionally, faster door-to-balloon time for STEMI patients leads to reduced healthcare costs, heart attack rates, and hospital stays.
A large study found that patients with established arterial disease have significantly higher cardiovascular event rates than those with multiple risk factors only. The rates increased directly with the number of symptomatic arterial disease locations, emphasizing the need for improved secondary prevention and clinical outcomes.
Researchers at the University of Pennsylvania's School of Medicine identified key risk factors associated with increased hospital admission rates following outpatient surgery. These risk factors include age, operating time, cardiac diagnoses, and certain medical conditions.
Research reveals that nearly one in three women experience painful sex a year after childbirth and over half have at least one sex-related health problem. Asian women were more likely to report health problems than white women, while Afro-Caribbean women displayed similar levels of ill health.
Research from the Framingham Heart Study found that people with long-lived parents are more likely to avoid high blood pressure, cholesterol, and other cardiovascular risk factors in middle age. Long-lived parents also conferred a lower risk of cardiovascular disease over time.
A comprehensive review highlights clinically relevant differences in women and men's heart disease prevalence, presentation, management, and outcomes. Young women with acute coronary syndrome face higher mortality rates than young men.
A study by researchers at the University at Buffalo's Research Institute on Addictions found that 18% of young women experienced sexual victimization over a two-year period. The majority (66%) of these cases involved intimate partners, highlighting the need for tailored prevention strategies to address both types of victimization.
Individuals with one or more long-lived parents may have fewer risk factors for heart disease in middle age, according to a study. Those whose parents survived to age 85 or older tend to have optimal blood pressure, cholesterol levels, and lower cardiovascular risk scores.
A study by Duke University Medical Center found that having both type 2 diabetes and depression significantly increases the risk of death for heart patients. This is because individuals with diabetes who also experience depression may be less motivated to follow their self-care regimen, thereby putting them at a higher risk.
A study found that white adolescents with high exposure to R-rated movies and unsupervised television viewing are more likely to start smoking. However, this association was not seen in black adolescents, who were equally likely to initiate smoking regardless of media exposure. The reasons for these racial differences are unclear.
A new study by the American Heart Association found that Hispanic women have a similar heart disease risk to Caucasian women who are about a decade older. This challenges the long-held belief that Hispanic women have less heart disease than Caucasian women.
Researchers discovered a rare genetic mutation that causes early onset coronary artery disease in an Iranian family. The mutation, in the LRP6 gene, leads to high blood pressure, high cholesterol, and diabetes, all risk factors for heart disease.
Primary graft dysfunction is a significant risk factor for bronchiolitis obliterans syndrome (BOS), a chronic scarring process that affects lung function years after transplantation. The study found that all grades of primary graft dysfunction were associated with an increased risk of BOS.
Researchers found that adult participants who met with pharmacists during a community outreach project showed significant reductions in metabolic syndrome risk factors and heart disease risk after four months. The study suggests that pharmacist-driven education and lifestyle recommendations can help combat metabolic syndrome.
A study of 110,599 women found that long-term strenuous physical activity reduced the risk of invasive and in situ breast cancer by 20% and 31%, respectively. Moderate physical activity did not show a significant impact on breast cancer risk.
A study identified pulse pressure as an important predictor of atrial fibrillation development, with increased stiffness associated with higher risk. The research found that a 20 mm Hg increase in pulse pressure was linked to a 34% increased risk of developing AF.
Researchers found that women with pre-diabetic markers are at higher risk of cardiovascular disease and may benefit from more intense screening. The study suggests that the 'diabetes clock' starts ticking sooner for women than men, contributing to sex differences in heart disease mortality.
A new risk-factor list for postmenopausal women could help reduce cardiovascular disease deaths by incorporating family history and C-reactive protein. The updated criteria may change the risk scores for at least 20% of studied women.
Researchers developed and validated two clinical algorithms to predict global cardiovascular risk in women, showing improved accuracy and reclassification of 40-50% of those at intermediate risk. The Reynolds Risk Score calculator is freely accessible online.
Taking regular midday naps is linked to a lower risk of death from heart disease in Greek adults. Among working men, systematic napping for 30 minutes or more three times a week reduces the risk by 64%.
Pregnant women over 40 years old are at higher risk of stillbirth due to various pregnancy complications. Fetal testing at 38 weeks gestation is most effective in reducing stillbirth rates among older women.
Research links depressive symptoms to early signs of artery disease, including thickening of carotid arteries. The study suggests that physical symptoms of depression, such as fatigue and appetite disturbance, may play a role in the development of coronary artery disease.
A European study reviews various studies on risk reduction attributed to fiber and antioxidants in 100% fruit juices and whole fruits/vegetables. It concludes that pure fruit and vegetable juices are comparable in reducing risk factors for certain diseases like cancer and cardiovascular disease.
A study of 5,008 adults found that daily use of selective serotonin reuptake inhibitors (SSRIs) is associated with a doubled risk of certain fractures. The use of SSRIs was also linked to an increased risk of falls and decreased bone mineral density.
A study published in JAMA found that South Asians have higher levels of heart attack risk factors, such as smoking and diabetes, at younger ages. The research suggests that lifestyle changes implemented early in life can reduce the risk of heart attacks in South Asians.
A new study reveals that women who outwardly express anger may be at increased risk of heart disease if they also have certain risk factors such as diabetes, unhealthy levels of fats in the blood, or age. The researchers found that only expressed anger, not just cynicism or hostility, was predictive of coronary artery disease in women.
The American Journal of Lifestyle Medicine is exploring how lifestyle choices impact heart disease. The journal focuses on recognizing and addressing the impact that lifestyle decisions have on health, emphasizing traditional therapies and lifestyle modalities to achieve superior outcomes in disease treatment.
A recent study published in Archives of Ophthalmology found that genetic predisposition and exposure to modifiable risk factors significantly multiply the risk for age-related macular degeneration (AMD). Individuals with two mutated alleles of genes CFH and LOC387715 were 50 times more likely to develop AMD.
A comprehensive review published in the journal SLEEP found that environmental exposures before the age of onset in genetically susceptible individuals may contribute to the development of narcolepsy. The study suggests intensifying the search for these exposures and focusing on the first two decades of life to prevent the disease.
A study of Finnish working-aged adults found that pet ownership is associated with a higher risk of illness and lower physical activity levels. Dog owners did exhibit increased physical activity compared to non-dog owners, however this was not enough to offset the negative health effects of pet ownership.
The study found a significant decline in stroke incidence over the past 50 years, with lifetime risk decreasing from 19.5% to 14.5%. However, age-adjusted stroke severity remained unchanged, and mortality rates only decreased in men, highlighting the need for greater primary prevention efforts.
A study published in Neurology found that a gene variation linked to longevity also protects brain function in individuals over 90. Researchers analyzed 158 centenarians and found they had twice the likelihood of good brain function compared to those without the variant.
A study found that prostate cancer treatment costs are substantial and sustained, with cumulative costs averaging $42,570 over five years. The cost of treatments varies by type, age, and disease risk, with watchful waiting being the least expensive option.
A study suggests that even commonly used biomarkers are limited in their ability to predict cardiovascular risk. BNP and urinary albumin content were found to be the most useful in predicting future events, but only slightly improved predictions based on conventional risk factors.
Scientists found that persons with high multimarker scores had a risk of death four times as great and a risk of major cardiovascular events almost two times as great as those with low scores. The study used 3209 participants for 10 years, measuring 10 novel biomarkers in addition to established risk factors.
A study found that children who received light therapy (phototherapy) for jaundice as infants had an increased risk of developing skin moles in childhood. The study, published in Archives of Dermatology, examined 58 French children and found a significant association between phototherapy and the number of moles
A study found that TV viewing and low physical activity are associated with increased risk of metabolic diseases in children. However, physical activity was inversely related to blood pressure, glucose, insulin, triglycerides, and overall risk score. Preventive action may need to target both TV viewing and physical activity separately.
A University of Cincinnati-led study aims to identify specific genes associated with metabolic syndrome. Researchers will collect data from a genetically isolated population in Croatia to understand the complex relationship between genetics and lifestyle choices that contribute to the condition.
Researchers found a strong association between child and parent cardiovascular risk factors, including body mass index, waist circumference, and lipid profiles. Screening children can lead to interventions in both children and their parents to reduce disease risk.
A large survey of male Marine Corps recruits aged 18-20 found that young men who started drinking at a young age were more likely to be risky drinkers. Risk factors also included tobacco use, rural hometown, and childhood abuse.