A Europe-wide study aims to identify the key factors contributing to asthma development, with a long-term goal of prevention. The GABRIEL project will analyze genetic and environmental interactions, including the role of urbanization and industrial agents, to better understand this complex disease.
A Université de Montréal study found that boys identified as hyperactive, fearless, and not prosocial at age six are 6 times more likely to join a deviant peer group. Family adversity also increases the risk of early gang affiliation.
A whole-genome study at Johns Hopkins reveals a new gene, NOS1AP, associated with abnormal heart rhythm and increased risk of sudden cardiac death. Approximately 60% of European descent individuals carry a variant of this gene linked to QT interval length.
Data from the National Health Interview Survey show a significant link between obesity and increasing diabetes incidence. Lifestyle interventions, including moderate weight loss and exercise, can prevent or delay diabetes onset in high-risk adults.
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The study found that patients' lung volumes are lower following surgery and general anesthesia, increasing the risk of developing pneumonia, respiratory failure, or worsening existing lung disease. The guidelines provide patient-related risk factors and surgery-related risk factors to assess pulmonary complications.
A study found that nearly half of elderly Beijing residents have metabolic syndrome, a cluster of five risk factors for cardiovascular disease. The prevalence of metabolic syndrome in China is on par with Western populations, posing a significant burden on the healthcare system.
A study has found that taller people are more likely to develop atrial fibrillation, with the risk increasing by 32% for those in the tallest quartile compared to the shortest. The researchers suggest that tall individuals may need more aggressive risk factor attenuation strategies.
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A study of 37,692 DCIS and 4,490 LCIS patients found LCIS patients were at greater risk for invasive lobular carcinoma ILC and ipsilateral invasive breast cancer. The research suggests LCIS may be a precursor lesion to ILC and warrants localized treatment.
Women who consumed up to two drinks per day scored higher on the Mini Mental State Exam compared to non-drinkers or occasional drinkers. The study suggests moderate drinking is protective for women's cognition, contradicting previous research on large vessel atherosclerosis as a mediating factor.
Research identifies three estrogen-related gene variants associated with an increased risk of Parkinson's disease in women. The study found that these genetic variations affect 10-20% of the female population and could be used to predict disease risk using a simple blood test.
This study compares pregnancy risks and outcomes among babies born to foreign-born Asian-Indian, U.S.-born Asian-Indian, foreign-born Mexican, and U.S.-born Mexican mothers. Foreign-born Asian-Indian women face higher rates of low birth weight and small for gestational age babies despite a low-risk socio-demographic profile.
A new study published in Obesity Research suggests that visceral fat is strongly correlated with waist circumference and independently predicts mortality risk. The researchers recommend measuring waist circumference as a routine measure in clinical practice to predict the risk of future disease and mortality.
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A study of 186 cognitively normal adults aged 70+ found that performance on cognitive tests of executive control and memory predicted walking speed without interference. Gait velocity with interference was also affected by executive control and memory, highlighting the importance of these functions in navigating busy environments.
Children born preterm show cognitive and motor deficits, while early social environment plays a significant role in development. fMRI scans reveal distinct brain activation patterns related to medical and environmental risks.
The Fairbanks Institute will conduct a long-term predictive health study using biologics and medical informatics to identify risk factors for cardiovascular disease. Researchers will monitor participants over years to understand biological compensation and gene-environment interactions.
A study found that owning alcohol-branded items increased the likelihood of initiating alcohol use in teens. Students who owned these items were 1.5 times more likely to start drinking than those who didn't, according to researchers.
A new study is recruiting over 3,500 rugby union players aged 16-35 to gather data on head injuries and recovery. The research will inform the development of evidence-based guidelines to manage player return to sport after concussion.
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A new analysis by Duke Clinical Research Institute researchers reveals that Lumbees have a significantly higher burden of cardiovascular risk factors. The study found that Lumbees who came to the hospital for heart treatment had higher rates of diabetes, hypertension, and prior history of coronary artery disease.
Researchers found increased clotting marker concentrations during flights compared to sitting and daily activities, suggesting additional mechanisms underlying air travel-related thrombosis. The study included 71 healthy volunteers with varying risk factors for thrombosis, including genetic mutations and oral contraceptives.
Women's heart health is underestimated due to differing risk factors compared to men. The European Society of Cardiology recommends considering age as a significant factor in diagnosis and treatment planning for women.
Researchers have identified two genes, Factor H and Factor B, that explain nearly three out of four AMD cases. The study suggests a specific immune response pathway plays a central role in the disease's development.
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A new study by Johns Hopkins Medicine found that men with low-grade prostate cancer who receive active surveillance may not be at increased risk of noncurable prostate cancer. The study compared outcomes in men who delayed surgery for two years to those who underwent immediate treatment, finding no significant difference in risk.
A study assessing H-pylori status in patients with gastric adenocarcinoma found that positive individuals had improved survival rates compared to those negative for the bacteria. The results suggest that H-pylori status can be a useful tool in clinical practice to distinguish between high and low risk patients.
Scientists have identified two blood clotting genes associated with an increased risk of coronary disease, finding that genetic variants of factor V and prothrombin increase thrombin production. The study suggests the need for bigger studies to identify other genetic causes of heart attacks.
Research suggests a connection between periodontal disease and atherosclerosis, which may be driven by bacteria from gum infections entering the bloodstream. This study emphasizes the importance of managing both oral health and cardiovascular risk factors to reduce overall disease risk.
The incidence of breast cancer in Korea is increasing, with a significant rise in the proportion of asymptomatic patients detected by mammography. This trend reflects the country's westernization and lower breastfeeding rates, leading to higher risk factors such as early menarche and obesity.
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Current support systems for men with breast cancer are rudimentary, highlighting the need for national protocols that provide information and emotional support. Risk factors include occupational exposure to high temperatures, genetic abnormalities, and excess alcohol, which increase the risk of the disease.
Researchers developed an index to predict mortality risk in older adults, based on demographics, illnesses, and ability to perform daily activities. The 12-question form can be completed quickly by patients or medical office staff, providing valuable prognostic information for healthcare providers.
A midriff bulge roughly doubles a woman's chances of needing gallstone surgery, according to a comprehensive study. The study, which monitored over 42,000 women for two years, found that women with larger waist sizes were more likely to develop gallstones.
A worldwide study is screening 220,800 healthy babies for genes that increase risk of developing type 1 diabetes. The researchers aim to identify environmental triggers that determine the risks for the disease.
A large twin study found that genetic factors are highly influential in Alzheimer's disease development, with identical twins showing similar age at onset. The study suggests genes play a key role in disease timing, with concordance rates higher in women due to their greater longevity.
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Research finds that women's heart disease has distinct characteristics, including cellular and microvascular dysfunction. The study highlights the importance of considering gender-specific risk factors and diagnostic tools to improve detection and treatment.
A recent study published in the Canadian Medical Association Journal found a strong correlation between height and the risk of amputation among patients with diabetes mellitus. The research showed that every 10-cm increase in height was associated with a 16% higher risk of amputation, even among those with well-controlled diabetes.
A new prediction rule identifies patients with pulmonary embolism who are at low risk of short-term mortality and other adverse medical outcomes, making them eligible for outpatient treatment. The model accurately predicted low-risk patients in two studies, resulting in very low mortality rates within 30 days.
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Studies found that erectile dysfunction is common among men and associated with various chronic diseases, including heart disease. The condition was also linked to increased risk of future cardiovascular events, diabetes, and hypertension.
Fecal incontinence affects 7.2% of US women aged 30-90, often accompanied by urinary incontinence and other medical conditions like diabetes or major depression. Treatment options include diet changes, medications, surgery, and biofeedback exercises.
Researchers analyzed data from the REACH Registry to determine the prevalence and treatment of atherosclerosis risk factors in 67,888 patients from 44 countries. The study found that high proportions of patients had hypertension, hypercholesterolemia, and diabetes.
A study published in the American Journal of Human Genetics has identified a genetic region on chromosome 10 strongly associated with late-onset Alzheimer's disease. The researchers scanned over 1,400 single-nucleotide polymorphisms and found six genes within this region that may be involved in the development of the disease.
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A study of over 6,600 children found that those raised in Steiner schools had lower rates of allergic symptoms and diagnoses compared to non-Steiner peers. Early antibiotic use and vaccinations were linked to increased allergy risks.
Researchers found that obese individuals had significantly higher risks of hospitalization and mortality from cardiovascular disease and diabetes in older age compared to those with normal weight. The study's findings support the importance of primary prevention of overweight and obesity to combat the worsening epidemic.
A study by Washington University researchers found a single base variation in the TAS2R16 receptor gene that increases the risk of alcohol dependence, with higher incidence in African Americans and lower sensitivity to bitter tastes among those with this variant.
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Researchers found that childhood sexual abuse, poor parent-child relationships, and low social support were common risk factors for depression in both men and women. However, the study revealed that childhood parental loss and low self-esteem were more potent variables in men than in women.
A study by UCSF researchers found that medical students with early warning signs of unprofessional behavior were nearly nine times more likely to be disciplined as practicing physicians. The study recommends reviewing medical school admissions and graduation standards to include explicit language about professional behavior.
A study of over 9,400 men found a strong association between erectile dysfunction and subsequent cardiovascular disease, including angina, myocardial infarction, stroke, and transient ischemic attack. Men with erectile dysfunction were found to have a 25-45% increased risk of cardiovascular events compared to those without the condition.
Researchers analyzed data from over 41,000 adults and found a significant association between tooth loss and heart disease, even among those who had never smoked. The study highlights the importance of promoting good oral health to prevent cardiovascular disease.
Research reveals that nearly 20% of U.S. adolescents and adults under 50 have low cardiorespiratory fitness, associated with higher risks of heart disease and other chronic conditions. Low fitness is more common in females, non-Hispanic blacks, and those with higher body mass index and waist circumference.
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A novel partnership between Indian institutions and the government aims to document the causes of death in rural and urban areas. The Verbal Autopsy method has already demonstrated reliable measurement of deaths in young and middle-aged individuals, and will be expanded to collect physical measurements and blood samples.
Researchers found a significant association between women who have experienced recurrent SIDS and complications in future pregnancies, including smaller gestational age infants and preterm deliveries. The study suggests a possible mechanism for recurrent SIDS that may be linked to previous infant death.
Research published in The Lancet suggests that light to moderate alcohol consumption may have little to no health benefits, outweighing the potential harms. Professor Rod Jackson's findings emphasize that there is no 'safe' window for drinking, and individuals should avoid consuming alcohol altogether.
A gene variant in Complement Factor H is associated with an increased risk of soft drusen, a precursor to advanced age-related macular degeneration. The study found that the CFH variant contributes to the development of soft drusen but does not determine who will progress to advanced AMD.
Researchers found that higher levels of inflammatory markers Lp-PLA2 and CRP were associated with increased risk of ischemic stroke. The study included 12,762 middle-aged men and women, and found that individuals with high levels of both markers were at the highest risk.
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A large cohort study found that octogenarians undergoing open heart surgery have a 72% higher risk of death, longer hospital stays, and increased neurologic complications compared to younger patients. Age is an independent risk factor for morbidity and mortality after controlling for other variables.
Nine behavioral and environmental risk factors contribute to a third of global cancer deaths. Lifestyle changes and environment modifications can prevent many types of cancer.
Researchers found that nine modifiable risk factors contribute significantly to cancer mortality worldwide. These include low fruit and vegetable intake, physical inactivity, and exposure to urban air pollution. Implementing lifestyle and environmental interventions can prevent a substantial proportion of cancer-related deaths.
Researchers found that replacing carbohydrates with protein and unsaturated fat can lower blood pressure, improve cholesterol levels, and reduce the risk of heart disease. The OmniHeart study suggests that these modifications can be effective in reducing some risk factors and estimated risk for heart disease.
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The NHLBI research presented at the American Heart Association's scientific sessions highlights important findings on women and heart disease, including a link between high levels of male sex hormones and coronary artery disease in postmenopausal women. The study also explores the impact of socioeconomic status on cardiovascular diseas...
Researchers found a significant negative correlation between urine albumin levels and adiponectin hormone in obese mice. In humans, low adiponectin levels were associated with albuminuria, an indicator of kidney disease.
The study found that children who ate out more frequently had higher systolic and diastolic blood pressure, lower levels of good cholesterol, and smaller LDL particle size. They also consumed more starch, sugar, sodium, fat, and cholesterol than their peers who ate at home.
A recent study suggests that current medical research methods are flawed and may miss signs of harm or benefit in subgroups of patients. Risk-stratified analysis, which considers multiple factors, can help detect these issues and provide more accurate information for doctors to discuss with patients.
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A three-year study by the University of Manchester found that people migrating from India to Britain are at greater risk of cardiovascular disease due to higher body mass, blood pressure, and cholesterol levels. The research highlights the importance of adopting a healthy lifestyle with a balanced diet and regular exercise.