NEJM Clinician curates highly relevant clinical insights from over 150 peer-reviewed journals to give physicians clear guidance without the noise. The weekly publication delivers summaries and commentary in a concise, 30-minute read, helping healthcare providers stay informed and confident in their decisions.
Dr. Langlois and his team will support large-scale scientific research, protect vulnerable communities, and strengthen Canada's ability to face future health emergencies. The High-Throughput Facility infrastructure will rapidly detect and track new infectious disease threats while protecting people and communities.
A new technology using microscopic beads marked with stable isotopes enables the simultaneous detection of dozens of different antibodies in hundreds of samples. This expands the capacity of serological analysis for biomedical research, vaccine development, and epidemiological studies.
The US Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus infection, even in symptomatic individuals. The lifelong nature of HSV infection means there is no cure, but antiviral medications can provide clinical benefits to those experiencing symptoms.
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Researchers found that elderly Japanese individuals show a low immune response to the third mRNA COVID-19 booster vaccine. The study revealed that nearly 10% of participants had negligible antibody production despite receiving an additional dose. The findings suggest that elderly people may require specialized serological testing proto...
A Tel Aviv University study challenges the widely-held assumption that COVID-19 originated from bats, instead highlighting their highly effective immune system. The researchers found that many reported findings on bat-borne viruses are based on antibody presence or PCR tests rather than actual virus isolation.
A French study of nearly 27,000 individuals found that persistent physical symptoms like fatigue and breathlessness after COVID-19 may be more closely tied to beliefs about having been infected than actual lab confirmation. The research suggests a possible psychological component to lingering symptoms.
A recent study published in JAMA Oncology found that the Pfizer-BioNTech vaccine appears to be safe and effective in patients with cancer, achieving satisfactory serologic status. Despite a lag in antibody production compared to non-cancer control groups, most patients experienced seroconversion after the second dose.
Estimating the severity of a flu epidemic can be done in real-time using serological data coupled with clinical surveillance data. This approach provides valuable insights for pandemic preparedness and response, making it useful not only for influenza pandemics but also for other emerging infectious diseases.
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A 26-year study found that 18 months of combined antibiotic therapy with doxycycline and hydroxychloroquine is sufficient to make infection undetectable in most patients, but six patients experienced serological relapse after 15-24 months. The optimal treatment duration may be longer for prosthetic valve patients.
Researchers have developed an in-vitro antibody production technique to detect HIV infection earlier, reducing the diagnostic window period. This method promotes the synthesis and release of antibodies against HIV-1 prior to detection in plasma samples, leading to safer blood supply and improved diagnosis.