Researchers at Tokyo Metropolitan University have created a neutral molecule that can carry DNA into biological cells using a process called annealing. This breakthrough promises more effective therapies by reducing inflammation and improving delivery efficiency.
A new study found that only a quarter of reproductive health experts prescribe self-administered injectable contraceptives, despite its safety and effectiveness. The study identified barriers such as concerns about patient ability, medication availability, and lack of standardized counseling approaches.
A new UCF study found that insurance coverage of extended-release buprenorphine injections is lacking, with only 46% of commercial plans and 19% of Medicare Advantage plans covering it. Prior-authorization requirements also pose a barrier to access, particularly for Medicaid plans.
Researchers from the London School of Hygiene & Tropical Medicine found that intramuscular administration of tranexamic acid (TXA) is safe and quickly reaches therapeutic concentrations in pregnant women. Oral TXA was also well-tolerated but took an hour to reach therapeutic blood concentrations.
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In a phase III trial, elacestrant showed significant benefits in decreasing death or disease progression and increasing progression-free survival compared to standard of care. The treatment was well-tolerated with manageable side effects, offering hope for patients with ER-positive/HER2-negative metastatic breast cancer.
Intramuscular tranexamic acid injection can rapidly absorb and reach lifesaving levels within 15 minutes, expanding access to urgent treatment for trauma victims. The new method requires less training and takes less time than traditional intravenous injections.
A PATH study in Uganda found that self-administration of subcutaneous DMPA enables women to continue using injectable contraception longer than those receiving traditional injections. The study showed a 46% reduced risk of discontinuation among self-injecting women, with younger women benefiting most.
A Canadian study found that most nurses (71%) prefer using the dorsogluteal site for intramuscular injections, despite potential risks of sciatic nerve injury. Younger nurses were more likely to follow recommended best practices.
Researchers found that sucrose reduces overall pain in newborns during painful medical procedures, but not for intramuscular injections or heel-lancing. The study's results will help update pain management guidelines to better reduce pain responses in newborns.
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Researchers have found that tattooing is a more effective way of delivering DNA vaccines than intramuscular injection, producing stronger humoral and cellular immune responses. This method could have a role in routine vaccination of cattle or delivering therapeutic vaccines to humans.
Researchers at St. Jude Children's Research Hospital found that intramuscular injections of peramivir for 8 days protected mice from lethal H5N1 influenza virus infection and inhibited virus replication. This study supports the use of peramivir to control influenza during a pandemic.
Research by Victoria O. Chan reveals that 68% of intramuscular injections do not reach the muscle due to excessive fat tissue. The study suggests a longer needle length may improve success rates for patients with obesity.
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A new study found that an oral-solution form of Risperdal is just as effective as intramuscular injections in reducing symptoms of psychotic agitation. The oral solution may be a more acceptable alternative for both caregivers and patients, promoting patient choice and compliance.