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A spring-loaded sensor for cholesterol in cells

Researchers discovered that an enzyme called squalene monooxygenase (SM) responds to increased cholesterol levels by being destroyed, reducing cholesterol production. This finding could lead to new treatments targeting SM, potentially decreasing cholesterol levels.

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Molecular guardian defends cells, organs against excess cholesterol

Researchers at Harvard T.H. Chan School of Public Health discovered Nrf1 protein's role in maintaining cholesterol balance within cells. The protein senses and responds to excess cholesterol, promoting protective countermeasures and potentially treating diseases where cholesterol metabolism is disrupted.

UC-led study could bring about strategies to increase 'good' cholesterol

A research team from the University of Cincinnati has developed a consensus model of human apolipoprotein A-I, a key component of HDL, which could lead to new strategies for increasing good cholesterol. This breakthrough was achieved through collaborative effort and innovative use of indirect experimental techniques.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

New way to treat cholesterol may be on the horizon

Researchers at Houston Methodist discovered a new pathway in cholesterol elimination, revealing that it is eliminated from the body in just two minutes, challenging the current 40-year model. This finding has significant implications for developing new drugs to lower cholesterol and improving cardiovascular health.

Cholesterol byproduct hijacks immune cells, lets breast cancer spread

Researchers discovered that high levels of cholesterol metabolism's byproduct 27HC facilitates breast cancer metastasis by hijacking specific immune cells. The study identifies 27HC as a potential drug target to inhibit its creation or actions, offering hope for effective therapies against this aggressive form of cancer.

Fight against top killer atherosclerosis garners acclaimed NIH award

A team of researchers, led by Tony Kim, has developed an innovative lab chip called the human-coronary-artery-on-a-chip to explore new treatments for atherosclerosis. The study aims to improve understanding of high-density lipoprotein (HDL) interactions with proinflammatory proteins and vascular tissues.

High rate of prescriptions for new cholesterol medications never filled

A study published in JAMA Cardiology found that only 30.9% of patients prescribed PCSK9 inhibitors ever received therapy, largely due to copay costs and prior authorization processes. Patients with governmental insurance and those filled at specialty pharmacies were more likely to be approved.

Alcohol use affects levels of cholesterol regulator through epigenetics

Researchers found that drinking alcohol induces changes to a cholesterol-regulating gene, PCSK9, leading to differences in how cholesterol is processed. Higher methylation and gene expression of PCSK9 were associated with chronic heavy alcohol use, which can lead to lower PCSK9 protein levels due to liver damage.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Study examines dietary fats' impact on healthy, obese adults

A new study suggests that metabolically healthy obese adults consuming a diet high in unsaturated fats may be able to decrease their total cholesterol by 10 points. However, replacing saturated fats with unsaturated fats does not aid in weight loss.

Revisiting dietary fat guidelines? (PURE)

A large study found that high carbohydrate intake is linked to increased total mortality and non-cardiovascular mortality outcomes, while high fat intake is associated with lower risk. The study suggests that limiting total fat consumption may not improve health in populations.

GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Japanese study questions benefit of treat-to-target statin therapy (EMPATHY)

A Japanese study questioned the benefit of treat-to-target intensive statin therapy in patients with diabetic retinopathy, finding no significant reduction in cardiovascular events. However, subanalysis showed that reaching an LDL cholesterol target of less than 70 mg/dL significantly reduced primary endpoint incidence.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

How low should LDL cholesterol go?

Researchers found that ultra-low LDL cholesterol levels (below 10 mg/dL) significantly reduced cardiovascular event risk by over 40%. No adverse effects on cognition or safety endpoints were reported. The study suggests achieving low LDL cholesterol levels beyond current treatment targets may further reduce cardiovascular risk.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Researchers link high levels of 'good' cholesterol with excessive mortality

Researchers found that extremely high HDL levels are associated with a higher mortality rate than normal levels. Men with extremely high levels had a 106% higher mortality rate, while women had a 68% higher mortality rate. The study suggests that the focus on HDL as an important health indicator may need to be revised.

Cholesterol-lowering drugs may fight infectious disease

Duke scientists discovered a gene variant linked to susceptibility to typhoid fever and found that cholesterol-lowering drug ezetimibe protected zebrafish against Salmonella Typhi. The study provides insight into human susceptibility to infectious disease and potential avenues for protection.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Almonds may help boost cholesterol clean-up crew

A recent study found that consuming almonds regularly can improve HDL cholesterol levels and function in people with elevated LDL cholesterol. The almond diet resulted in a 19% increase in large HDL particles and improved HDL function by 6.4%, suggesting potential benefits for heart health.

Quitting statins after stroke may raise risk of another stroke

Researchers found that stopping statin drugs after a first ischemic stroke increases the risk of having another stroke within a year and death. The study suggests that statins should be a lifelong therapy for ischemic stroke patients if needed to lower cholesterol levels.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Mechanism shown to reverse disease in arteries

A study published in the Journal of Clinical Investigation reveals a mechanism to reverse disease in arteries by targeting an immune reaction. Researchers at NYU Langone Health discovered that certain immune cells can switch from promoting inflammation to healing, which can lead to reduced plaque growth and improved cardiovascular health.

New clues in puzzle over pre-eclampsia and cholesterol regulation

A study led by the University of Nottingham has uncovered new clues on the connection between pre-eclampsia and an increased risk of heart disease in later life. The research suggests that the body's normal defence mechanism for flushing out cholesterol from the blood may be disrupted by the illness.

Cholesterol -- a key player at the lung surface

Researchers at Lund University found that cholesterol impacts the molecular structure of the alveoli's surfactant film, influencing its mechanical properties and substance transport. The study provides new insights into the significance of cholesterol for lung surface properties.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

A muffin a day might just keep the doctor away

Researchers developed a 'good heart' muffin to help reduce the risk of heart disease through soluble fibre, meeting food standard guidelines for cholesterol-lowering properties. The muffins contain three grams of beta glucans, a healthy ingredient found in oats and cereals.

More than half of eligible US travelers skip their pre-trip measles vaccine

More than half of eligible US travelers fail to receive a pre-trip measles vaccine, despite clinical recommendations. This increases the risk of endemic measles outbreaks in the US. Researchers urge improved provider and traveler knowledge of measles as a travel-related illness and increased vaccination rates.

Social smoking carries same heart-disease risks as everyday habit

A large study of over 39,000 participants found that social smokers face the same high blood pressure and cholesterol risks as everyday smokers. The researchers advise clinicians to ask about social smoking in different ways to identify and help these individuals quit.

Heart disease risks experienced in childhood impact cognition later in life

A new study found that childhood and adolescent cardiovascular risk factors are associated with worse midlife cognition, regardless of adulthood exposure. High blood pressure and high cholesterol in childhood, adolescence, and young adulthood, as well as smoking in adolescence and young adulthood, were linked to impaired cognitive perf...

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

'Bad' air may impact 'good' cholesterol increasing heart disease risk

Research suggests that high levels of traffic-related air pollution can lead to lower levels of high-density lipoprotein (HDL) cholesterol, also known as "good" cholesterol. This can increase the risk of cardiovascular disease by reducing the number and functionality of HDL particles.

Stem cell drug screen yields potential alternative to statins

Researchers found that cardiac glycosides, a class of heart failure drugs, can reduce LDL cholesterol levels in patients who don't respond to statins. The study used liver-like cells generated from patient stem cells and showed significant reductions in ApoB levels, indicating potential for a new treatment option.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Does boosting 'good' cholesterol really improve your health?

A new review suggests that augmenting the function of HDL cholesterol rather than increasing its concentration is crucial for protecting against cardiovascular disease. The study highlights the importance of addressing adipose tissue-associated inflammation to support the atheroprotective role of HDL.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

No benefit of synthetic HDL-C on arterial plaque

A Phase 2 trial found that synthetic high-density lipoprotein cholesterol (HDL-C) injections had no effect on reducing fatty deposits in arteries, despite being well-tolerated. The study's findings suggest that low-dose CER-001 may not be a promising agent for treating patients with acute coronary syndrome.

No evidence of cognitive issues when evolocumab added to statin therapy

The EBBINGHAUS study, the largest and most rigorous study on the topic, found no significant cognitive effects from adding evolocumab to statin therapy. The study enrolled 1,974 patients and used validated neurocognitive tests to assess executive function, working memory, and reaction time.