USC researchers have identified a protein fragment, PEP, that can increase the effectiveness of chemotherapy drugs against tumors. By making tumor blood vessels more permeable, PEP allows for better drug uptake and increased chemotherapy efficacy.
Researchers at Vanderbilt University Medical Center have identified a new protein called Interleukin 24 (IL-24) that is expressed in colon cancer cells and promotes cell growth or prevents cell death. The discovery could lead to the development of molecules to interrupt an autocrine loop, potentially fueling tumor growth.
A new protein, IL 13-PE38QQR, has shown high specificity and sensitivity to kill cancer cells, including those with Kaposi's sarcoma. The compound targets receptor sites on cancer cells, gaining access through interleukin 13.