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Science News for May 20, 2003


Better end-of-life care in the ICU

A national survey of ICU directors found that over 85% identified at least one large barrier to end-of-life care, including unrealistic expectations and insufficient training in communication. The survey also revealed that widely endorsed strategies such as training and symptom management are not always available in institutions.

Major government study: Surgery is a good option for selected emphysema patients

A major government study found that surgery provides significant improvements in pulmonary function, exercise tolerance, and quality of life for selected emphysema patients. The study identified specific criteria, including CT scan patterns and exercise capacity, to determine which patients are best suited for surgical therapy.

SourceCedars-Sinai Medical Center·JournalNew England Journal of Medicine·DateMay 20, 2003

Landmark cooperative study defines the role of lung surgery in the treatment of severe emphysema

A landmark cooperative study found that patients with upper lobe emphysema and low exercise capacity benefit more from lung volume reduction surgeries (LVRS), while those without these characteristics experience decreased survival and functional levels. LVRS improved lung function and exercise capacity, but had no long-term benefits.

SourceNIH/National Heart, Lung and Blood Institute·JournalNew England Journal of Medicine·DateMay 20, 2003

National emphysema results confirm Washington University findings

A national multicenter trial confirms that lung volume reduction surgery (LVRS) significantly improves the quality of life and life expectancy for patients with severe emphysema. The procedure, which involves removing diseased sections of lung tissue, allows patients to resume routine activities without breathing difficulties.

SourceWashU Medicine·JournalNew England Journal of Medicine·DateMay 20, 2003

Tea fights bad breath

A laboratory study found that tea polyphenols inhibited the growth of oral bacteria, reducing volatile sulfur compounds. The study also showed that low concentrations of polyphenols hindered the enzyme catalyzing hydrogen sulfide formation, cutting its production by 30%.

Other highlights of the May 21 JNCI

Researchers have discovered a second mechanism by which LPA promotes ovarian tumor growth through increased cyclin D1 protein levels. Additionally, the identification of PEP, a peptide fragment with vasopermeability activity, may help reduce toxicity in cancer immunotherapy. A new study also suggests that p16 inhibitors play a role in ...

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateMay 20, 2003

$2.96 million for nuclear research center at Rutgers

The new center will conduct basic nuclear science research and partner with the Oak Ridge National Laboratory to acquire specific data for the DOE's scientific and engineering effort to maintain the nation's nuclear weapons. The partnership aims to engage faculty, postdoctoral researchers, and students in nuclear science research.

Partners seek city's footprint

A partnership between Cardiff University and the city council aims to determine the Welsh capital's ecological footprint, providing valuable data for planners to link economic growth and environmental protection. The study will help reduce the city's footprint in areas such as transport, energy, waste, and resource use.