Articles tagged with Metabolic Networks
Researchers have created a virtual human metabolic network that allows them to quickly discover the effects of changing metabolic reactions on cell behavior. The tool can be used to study hundreds of human disorders and potentially tailor diets for weight control, as well as develop new cholesterol-lowering drugs.
The BIDMC research team is studying the hormones and brain pathways regulating body weight and glucose metabolism, with a goal of advancing diabetes treatment and prevention. Jointly funded by the Smith Family Foundation and the American Diabetes Association, this award supports scientists conducting research on type 2 diabetes.
Researchers discovered a promising drug, benfotiamine, that completely blocked three biochemical pathways damaging blood vessels in diabetic rats. The study found that benfotiamine successfully normalized retinal tissue and prevented diabetic retinopathy in the animals.
Research reveals women fatigue less than men under aerobic conditions, but equally when deprived of oxygen. Efficient utilization of aerobic pathways results in reduced by-product production, leading to decreased muscle fatigue. Further study is needed to explain the mechanism behind this difference.
A study has found that methylotrophic bacteria and methanogenic archaea share common central carbon metabolism pathways involving C1 transfer reactions. These findings have implications for understanding the evolutionary history of these pathways in all organisms.
Researchers discovered a plant-like metabolic pathway essential for survival of certain parasites, including those causing malaria, toxoplasmosis, and cryptosporidiosis. The finding provides new targets for anti-parasitic medications, including the possibility of medicines related to herbicides.